*
The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities,
and for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.
The information required in the remainder of this cover page shall not be
deemed to be "filed" for the purpose of Section 18 of the Securities Exchange
Act of 1934 (the "Act") or otherwise subject to the liabilities of that section
of the Act, but shall be subject to all other provisions of the Act (however,
see the Notes.)
Item 1.
|
|
(a)
|
Name of Issuer
Ionis Pharmaceuticals, Inc.
|
|
(b)
|
Address of Issuer's Principal Executive Offices
2855 Gazelle Court
Carlsbad, CA
92010
|
Item 2.
|
|
(a)
|
Name of Person Filing
Wellington Management Group LLP
Wellington Group Holdings LLP
Wellington Investment Advisors Holdings LLP
Wellington Management Company LLP
|
|
(b)
|
Address of Principal Business Office or, if None, Residence
c/o Wellington Management Company LLP
280 Congress Street
Boston, MA
02210
|
|
(c)
|
Citizenship
Wellington Management Group LLP -
Massachusetts
Wellington Group Holdings LLP -
Delaware
Wellington Investment Advisors Holdings LLP -
Delaware
Wellington Management Company LLP -
Delaware
|
|
(d)
|
Title of Class of Securities
Common Stock
|
|
(e)
|
CUSIP Number
462222100
|
Item 3.
|
If This Statement is Filed Pursuant to
Rule 13d-1(b), or 13d-2(b) or (c),
Check Whether the Person Filing is a:
|
|
(a)
|
[ ]
|
Broker or dealer registered under Section 15 of the Act (15 U.S.C. 78o).
|
|
(b)
|
[ ]
|
Bank as defined in Section 3(a)(6) of the Act (15 U.S.C. 78c).
|
|
(c)
|
[ ]
|
Insurance Company as defined in Section 3(a)(19) of the Act (15 U.S.C. 78c).
|
|
(d)
|
[ ]
|
Investment Company registered under
Section 8 of the Investment Company Act of 1940
(15 U.S.C. 80a-8).
|
|
(e)
|
[X]
|
An investment adviser in accordance with
Rule 240.13d-1(b)(1)(ii)(E);
*
|
|
(f)
|
[ ]
|
An employee benefit plan or endowment fund in accordance with
Rule 240.13d-1(b)(1)(ii)(F);
|
|
(g)
|
[X]
|
A parent holding company or control person in accordance with
Rule 240.13d-1(b)(1)(ii)(G);
|
|
(h)
|
[ ]
|
A savings association as defined in
Section 3(b) of the Federal Deposit Insurance Act
(12 U.S.C. 1813);
|
|
(i)
|
[ ]
|
A church plan that is excluded from the
definition of an investment company under
Section 3(c)(14) of the Investment Company Act
of 1940 (15 U.S.C. 80a-3);
|
|
(j)
|
[ ]
|
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(J).
|
|
|
If this statement is filed pursuant to Rule 13d-1(c),
check this box [ ]
|
|
Wellington Management Group LLP -
HC
Wellington Group Holdings LLP -
HC
Wellington Investment Advisors Holdings LLP -
HC
Wellington Management Company LLP -
IA
|
Item 4.
|
Ownership.
|
Provide the following information regarding the aggregate number and
percentage of the class of securities of the issuer identified in Item 1.
|
|
(a)
|
Amount Beneficially Owned:
|
|
See the responses to Item 9 on the attached cover pages.
|
|
(b)
|
Percent of Class:
|
|
See the responses to Item 11 on the attached cover pages.
|
|
(c)
|
Number of shares as to which such person has:
|
|
(i)
|
sole power to vote or to direct the vote
|
0
|
|
(ii)
|
shared power to vote or to direct the vote
|
See the responses to Item 6 on the attached cover pages.
|
|
(iii)
|
sole power to dispose or to direct the disposition of
|
0
|
|
(iv)
|
shared power to dispose or to direct the disposition of
|
See the responses to Item 8 on the attached cover pages.
|
Item 5.
|
Ownership of Five Percent or Less of Class.
|
|
If this statement is being filed to report the fact that
as of the date hereof the reporting person has ceased to
be the beneficial owner of more than five percent of the
class of securities, check the following:
[ ]
|
Item 6.
|
Ownership of More than Five Percent on Behalf of Another Person.
|
|
The securities as to which this Schedule is filed
are owned of record by clients of one or more investment advisers identified
in Item 7 directly or indirectly owned by
Wellington Management Group LLP.
Those clients have the right to receive, or the power to direct the
receipt of, dividends from, or the proceeds from the sale of, such
securities. No such client is known to have such right or
power with respect to more than five percent of this class of
securities, except as follows:
Not Applicable.
|
Item 7.
|
Identification and Classification of the Subsidiary Which Acquired
the Security Being Reported on by the Parent Holding Company.
|
|
Pursuant to the instructions in Item 7 of Schedule 13G,
the following lists the identity and Item 3 classification
of each relevant entity that beneficially owns shares of the
security class being reported on this Schedule 13G.
|
|
Wellington Group Holdings LLP – HC
|
|
Wellington Investment Advisors LLP – HC
|
|
Wellington Management Global Holdings, Ltd. - HC
|
|
One or more of the following investment advisers (the “Wellington Investment Advisers”):
|
|
Wellington Management Company LLP – IA
|
|
Wellington Management Canada LLC – IA
|
|
Wellington Management Singapore Pte Ltd – IA
|
|
Wellington Management Hong Kong Ltd – IA
|
|
Wellington Management International Ltd – IA
|
|
Wellington Management Japan Pte Ltd – IA
|
|
Wellington Management Australia Pty Ltd - IA
|
|
The securities as to which this Schedule is filed by
Wellington Management Group LLP,
as parent holding company of certain holding companies and
the Wellington Investment Advisers, are owned of record by
clients of the Wellington Investment Advisers.
Wellington Investment Advisors Holdings LLP controls directly,
or indirectly through Wellington Management Global Holdings, Ltd.,
the Wellington Investment Advisers.
Wellington Investment Advisors Holdings LLP is owned by
Wellington Group Holdings LLP. Wellington Group Holdings LLP
is owned by Wellington Management Group LLP.
|
Item 8.
|
Identification and Classification of Members of the Group.
Not Applicable.
|
Item 9.
|
Notice of Dissolution of Group.
Not Applicable.
|
Item 10.
|
Certification.
By signing below I certify that, to the best
of my knowledge and belief, the securities
referred to above
were acquired and are held
in the ordinary course of business and
were not acquired and are not held for the purpose
of or with the effect of changing or
influencing the control of the issuer of the
securities and were not acquired and are not held
in connection with or as a participant in any
transaction having that purpose or effect.
|