OXIS INTERNATIONAL, INC. (OTCBB: OXIS, Paris: OXI), a Company with significant intellectual property and patents in the field of oxidative stress and developer of products for nutraceutical, cosmeceutical and disease prevention caused by oxidative stress/inflammation, announced that OXIS’ application to re-list on the bulletin board has been approved and the Company’s shares are now available for trading on the OTC bulletin board with the symbol: OXIS.OB. OXIS common stock was previously quoted on the Pink Sheets.

Mr. Tony Cataldo, Chairman and CEO of OXIS, stated, “We are very pleased that OXIS’ shares are now trading on the OTC bulletin board. This is another critical step as we continue to evolve to a listing on a major exchange such as NASDAQ and reflects the progress that OXIS has made over the last several months. The move to the bulletin board will increase OXIS’ exposure to investors and improve liquidity in the trading of its shares, leading, we believe, to increased shareholder value.”

Contact the Company at: 310-860-5184 for additional information about OXIS, or visit our web site: www.oxis.com

About OXIS International, Inc.

OXIS International, Inc. develops technologies and products to research, diagnose, treat and prevent diseases of oxidative stress/inflammation associated with damage from free radical and reactive oxygen species (ROS). The company holds the rights to several therapeutic classes of compounds in the area of oxidative stress, and has focused commercialization programs that include SOD (superoxide dismutase), MPO (myeloperoxidase), GPx (glutathione peroxidase), as well as a highly potent antioxidant, Ergothioneine, that may be sold over-the-counter (OTC) as a dietary supplement.

Forward-Looking Statement

This press release contains forward-looking statements that involve numerous risks and uncertainties. Actual results, performance or achievements could differ materially from those anticipated in such forward-looking statements as a result of certain factors, including those set forth in the Company’s filings with the Securities and Exchange Commission.

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