TIDMETX

RNS Number : 5745O

e-Therapeutics plc

11 October 2021

e-therapeutics plc

("e-therapeutics" or the "Company")

Patent Filing Applications

Further advancement in the Company's RNAi Platform Development

Oxford, UK, 11 October 2021 - e-therapeutics plc (AIM: ETX; OTCQX; ETXPF), a specialist in computational drug discovery with a focus on developing RNA interference ("RNAi") therapeutics, is pleased to announce new patent filings to protect the Company's proprietary RNAi platform technology for liver gene silencing.

The Company has recently filed five new patent applications relating to its innovative GalNAc-conjugated siRNA (short interfering RNA) construct designs, including around stabilising chemical modifications enabling specific hepatocyte (liver cell) targeting.

Ali Mortazavi, Chief Executive Officer of e-therapeutics, commented: "Since our capital raise in May, we have made excellent progress in all areas of the Company. We expect to present data from our RNAi platform in our Interim Results announcement on Tuesday 26 October, when the in vivo characterisation studies will have been completed."

Enquiries :

 
 e-therapeutics plc                            Tel: +44 (0)1993 883 
                                                                125 
 Ali Mortazavi, CEO                         www.etherapeutics.co.uk 
 Karl Keegan, CFO 
  Laura Roca-Alonso, CBO 
 
 
   SP Angel Corporate Finance LLP                Tel: +44(0)20 3470 
                                                               0470 
 Nominated Adviser and Broker 
 Matthew Johnson/Caroline Rowe (Corporate 
  Finance) 
 Vadim Alexandre/Rob Rees (Corporate 
  Broking)

About e-therapeutics plc

e-therapeutics plc is an Oxford, UK-based company integrating computational power and biology to accelerate the discovery of life-transforming medicines. The Company has developed and validated a powerful, disease and modality agnostic computational approach to drug discovery, leveraging its industry-leading expertise in network biology to fully capture and interrogate human disease complexity.

The Company's multi-disciplinary team builds computational models of biological functions to transform the search for new medicines, interventions, mechanisms and genetic support. Its biology-led in silico laboratory enables rapid hypothesis generation and phenotypic screening of millions of compounds leading to 100-1,000x higher hit rates in the wet lab and successful mode of action elucidation. Novel targets can also be identified, prioritised and assessed. Harnessing internal target gene discoveries, e-therapeutics is currently building an in-house pipeline of RNAi based medicines, using its proprietary GalNAc-siRNA technology.

e-therapeutics has deployed and validated its disease-agnostic computational drug discovery platform both in house and with partners, including Novo Nordisk, Galapagos NV and a US-based, top five pharmaceutical company.

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October 11, 2021 02:05 ET (06:05 GMT)

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