Silence Therapeutics PLC Director/PDMR Shareholding (4344H)
December 03 2020 - 03:44AM
UK Regulatory
TIDMSLN
RNS Number : 4344H
Silence Therapeutics PLC
03 December 2020
Director Dealing
3(rd) December 2020
LONDON, Silence Therapeutics plc, AIM:SLN and Nasdaq: SLN
("Silence" or "the Company"), a leader in the discovery,
development and delivery of novel short interfering ribonucleic
acid (siRNA) therapeutics for the treatment of diseases with
significant unmet medical need, today announces that, on the 30th
November 2020 and 1(st) December 2020, 4,700 and 1,000 American
Depositary Shares ("ADSs") respectively were purchased by Mark
Rothera, Chief Executive Officer of the Company, at $18.20 per ADS.
Each ADS is a tradeable security representing 3 of the Company's
Ordinary Shares
Following this purchase, Mark Rothera is interested in 5,700
ADSs representing 17,100 ordinary shares (0.02%) of the issued
share capital of the Company.
Notification and public disclosure of transactions by persons
discharging managerial responsibilities and persons closely
associated with them
1. Details of the person discharging managerial responsibilities
(PDMR) / person closely associated
a) Name Mark Rothera
--------------------------- ----------------------------------------------
2. Reason for the notification
---------------------------------------------------------------------------
a) Position / status Chief Executive Officer
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b) Initial notification Initial notification
/ Amendment
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3. Details of the issuer, emission allowance market participant,
auction platform, auctioneer or auction monitor
---------------------------------------------------------------------------
a) Name Silence Therapeutics plc
--------------------------- ----------------------------------------------
b) LEI 213800SSURRJBX85SQ91
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4 Details of the transaction(s): section to be repeated for
(i) each type of instrument; (ii) each type of transaction;
(iii) each date; and (iv) each place where transactions
have been conducted
---------------------------------------------------------------------------
a) Description of American Depositary Shares (ADS), each
the financial instrument, of which represents three (3) Ordinary
type of instrument Shares of 5 pence each in the capital
of Silence Therapeutics plc
Identification
code
ISIN US82686Q1013
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b) Nature of the transaction Purchase of Silence Therapeutics plc ADS
--------------------------- ----------------------------------------------
c) Prices(a) and volume(s) Price(s) Volume(s)
$17.98 1200 ADSs
----------
$17.99 500 ADSs
----------
$18.99 800 ADSs
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$18.35 200 ADSs
----------
$18.00 2000 ADSs
----------
$18.30 1000 ADSs
----------
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d) Aggregated information Aggregate Volume: 5,700 ADSs
- Aggregated volume Metric for Quantity: ADSs
- Price Aggregated Volume Price per ADS: $18.20
--------------------------- ----------------------------------------------
e) Date of the transaction 30 November 2020 (Time zone: Eastern Standard
Time)
1 December 2020 (Time zone: Eastern Standard
Time)
--------------------------- ----------------------------------------------
f) Place of the transaction Nasdaq Capital Market
--------------------------- ----------------------------------------------
Enquiries:
Silence Therapeutics plc Tel: +1 (646) 637-3208
Gem Hopkins, Head of IR & Corporate Communications
Investec Bank plc (Nominated Adviser and Tel: +44 (0) 20
Broker) 7597 5970
Daniel Adams/Gary Clarence
European IR Tel: +44 (0) 20
Consilium Strategic Communications 3709 5700
Mary-Jane Elliott/Chris Welsh/Angela Gray
silencetherapeutics@consilium-comms.com
US IR Tel: +1 (443) 213-0505
Westwicke Partners
Peter Vozzo
peter.vozzo@westwicke.com
About Silence Therapeutics plc
Silence Therapeutics is developing a new generation of medicines
by harnessing the body's natural mechanism of RNA interference, or
RNAi, to inhibit the expression of specific target genes thought to
play a role in the pathology of diseases with significant unmet
medical need. Silence's proprietary technology can be used to
engineer short interfering ribonucleic acids (siRNAs) that bind
specifically to and silence, through the RNAi pathway, almost any
gene in the human genome to which siRNA can be delivered. Silence's
wholly owned product candidates include SLN360 designed to address
the high and prevalent unmet medical need in reducing
cardiovascular risk in people born with high levels of
Lipoprotein(a) and SLN124 to address beta-thalassemia and
myelodysplastic syndrome. Silence is also developing a C3 targeting
programme, SLN500, in partnership with Mallinckrodt Pharmaceuticals
to reduce the expression of the C3 protein for the treatment of
complement pathway-mediated diseases. Silence maintains ongoing
research and collaborations with AstraZeneca, Mallinckrodt
Pharmaceuticals and Takeda. For more information, please visit:
https://www.silence-therapeutics.com/
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