RNS Number:4569S
Alexon Group PLC
25 November 2003


                           SCHEDULE 10
 
             NOTIFICATION OF MAJOR INTERESTS IN SHARES


1)   NAME OF COMPANY

     ALEXON GROUP PLC


2)   NAME OF SHAREHOLDER HAVING A MAJOR INTEREST

     CAPITAL GROUP


3)   Please state whether notification indicates that it is in respect of 
     holding of the Shareholder named in 2 above or in respect of a 
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18

     


4)   Name of the registered holder(s) and, if more than one holder, the 
     number of shares held by each of them.

     SEE LETTER BELOW


5)   Number of shares/amount of stock acquired.

     

6)   Percentage of issued Class



7)   Number of shares/amount of stock disposed



8)   Percentage of issued Class



9)   Class of security

     ORD 10P SHARES



10)  Date of transaction




11)  Date company informed

     24/11/03


12)  Total holding following this notification

     3,147,171

               
13)  Total percentage holding of issued class following this notification

     5.085%


14)  Any additional information




15)  Name of contact and telephone number for queries

     R PIGGOTT
     01582 723131


16)  Name and signature of authorised company official responsible for 
     making this notification


     Date of Notification     25 NOVEMBER 2003




LETTER TO:  ALEXON GROUP PLC  
DATED 14 NOVEMBER 2003

                          SECTION 198 NOTIFICATION 
                          Notification of Increase

This Notice is given by The Capital Group Companies. Inc. on behalf of its
affiliates, including Capital International SA, Capital International Limited,
Capital International, Inc., and Capital Guardian Trust Company, pursuant to
Section 198 of the Companies Act 1985.

The interest in the relevant share capital indicated below arises by virtue of
holdings attributed to the Companies (see Schedule A). These holdings form part
of funds managed on behalf of investment clients by the Companies.

Share capital to which this relates:

Ordinary Shares (61,893,001 shares outstanding) 

Number of shares in which the Companies have an interest;

3,147,171 

Name(s) of registered holder(s);

See Schedule B


As of 14 November 2003 

Alexon Group plc
 
                                               Number of Shares       Percent of
                                                                     Outstanding

The Capital Group Companies. Inc. ("CG") holdings   3,147,171          5.085%

Holdings by CG Management Companies and Funds:

-   Capital Guardian Trust Company                  2,230,794          3.604%

-   Capital International Limited                     781,529          1.263%

-   Capital International S.A.                         40,191          0.065%

-   Capital International, Inc.                        94,657          0.153%


                                    Schedule A



                    Schedule of holdings in Alexon Group plc 
                               As of 14 November 2003

                           Capital Guardian Trust Company
 

Registered Name                                                     Local Shares 

State Street Nominees Limited                                              9,452

Chase Nominees Limited                                                 1,915,172

Midland Bank plc                                                         210,463

Nortrust Nominees                                                         95,707

                                              TOTAL                    2,230,794




                               Capital International Limited

Registered Name                                                     Local Shares

Chase Nominees Limited                                                   781,529

                                              TOTAL                      781,529



                                 Capital International S.A.
 
Registered Name                                                     Local Shares

Citibank London                                                           40,191

                                              TOTAL                       40,191



                                 Capital International Inc.
 
Registered Name                                                     Local Shares 

State Street Nominees                                                     29,809

Chase Nominees Limited                                                    64,848

                                              TOTAL                       94,657

                                          Schedule B



                      This information is provided by RNS
            The company news service from the London Stock Exchange
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