MLNT Melinta Therapeutics Inc

SCHEDULE 13D/A

CUSIP No. 58549G 100

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CUSIP No 58549G 209

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CUSIP No 58549G 209

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CUSIP No 58549G 209

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CUSIP No 58549G 209

This Amendment No. 10 (this “ Amendment ”) amends the Schedule 13D originally filed with the Securities and Exchange Commission on November 3, 2017 (the “ Original Schedule 13D ”), the Amendment No. 1 to the Original Schedule 13D filed with the Securities and Exchange Commission on November 29, 2017 (“ Amendment No.  1 ”), the Amendment No. 2 to the Original Schedule 13D filed with the Securities and Exchange Commission on January 8, 2018 (“ Amendment No.  2 ”), the Amendment No. 3 to the Original Schedule 13D filed with the Securities and Exchange Commission on May 31, 2018 (“ Amendment No.  3 ”), the Amendment No. 4 to the Original Schedule 13D filed with the Securities and Exchange Commission on November 8, 2018 (“ Amendment No.  4 ”), the Amendment No. 5 to the Original Schedule 13D filed with the Securities and Exchange Commission on November 21, 2018 (“ Amendment No.  5 ”), the Amendment No. 6 to the Original Schedule 13D filed with the Securities and Exchange Commission on December 20, 2018 (“ Amendment No.  6 ”), the Amendment No. 7 to the Original Schedule 13D filed with the Securities and Exchange Commission on January 16, 2019 (“ Amendment No.  7 ”), the Amendment No. 8 to the Original Schedule 13D filed with the Securities and Exchange Commission on February 26, 2019 (the “ Amendment No.  8 ”) and the Amendment No. 9 to the Original Schedule 13D filed with the Securities and Exchange Commission on July 2, 2019 (the “ Amendment No.  9 ” and, collectively with the Original Schedule 13D, Amendment No. 1, Amendment No. 2, Amendment No. 3 Amendment No. 4, Amendment No. 5, Amendment No. 6, Amendment No. 7, and Amendment No. 8, the “ Schedule 13D ”) with respect to the shares of common stock, par value $0.001 per share (the “ Common Stock ”), of Melinta Therapeutics, Inc. (the “ Issuer ”), whose principal executive offices are located at 44 Whippany Road, Suite 280, Morristown, NJ 07960. The shares of Common Stock beneficially owned by the Reporting Persons as reported herein are referred to as the “ Shares. ” Information given in response to each item should be deemed incorporated by reference in all other items, as applicable. Capitalized terms used without definition in this Amendment have the meanings ascribed thereto in the Schedule 13D.

On February 20, 2019, the board of directors of the Issuer approved a 1-for-5 reverse stock split (the “Reverse Stock Split”). The Reverse Stock Split became effective as of 5:00 p.m. Eastern Time on February 21, 2019. The share numbers in this Amendment reflect the Reverse Stock Split.

Item 2. Identity and Background

Item 2(c) of the Schedule 13D is hereby amended to remove the sentence “Mr. Ferro also serves as a director and non-executive Chairman of the Issuer’s Board of Directors.” Mr. Ferro has resigned from the Issuer’s Board of Directors as reported on the Issuer’s Current Report on Form 8-K as filed with the Securities and Exchange Commission on August 9, 2019.

Item 5. Interest in Securities of the Issuer.

Item 5(a) of the Schedule 13D is hereby amended and restated as follows:

(a) The beneficial ownership percentages for the Reporting Persons described in this Amendment are based on 1,345,891 shares of Common Stock acquired directly by Vatera Healthcare in connection with the Merger, 355,555 shares of Common Stock acquired directly by Vatera Healthcare pursuant to the Equity Commitment Letter, 1,500,000 shares of Common Stock acquired directly by Vatera Healthcare pursuant to the Offering, 44,444 shares of Common Stock acquired directly by VHPM pursuant to the Equity Commitment Letter, 75,700 shares of Common Stock acquired directly by VHPM pursuant to the Offering, 9,375,000 shares of Common Stock underlying the Convertible Loans acquired directly by Vatera Healthcare pursuant to the A&R Loan Agreement (assuming that such Convertible Loans are converted into shares of Melinta preferred stock and then into Melinta

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common stock as of June 30, 2019 using the Conversion Amount, at a Common Stock Conversion Rate of 125 (equivalent to a Conversion Price of $8.00)) and 13,750,691 shares of Common Stock outstanding as of June 30, 2019, as reported in the Issuer’s quarterly report on Form 10-Q, filed on August 9, 2019. The deemed beneficial ownership of VCM and Mr. Ferro constitutes approximately 55.1% of the Common Stock of the Issuer outstanding as of June 30, 2019; the beneficial ownership of Vatera Healthcare constitutes approximately 54.5% of the Common Stock of the Issuer outstanding as of June 30, 2019; and the beneficial ownership of VHPM constitutes approximately 0.5% of the Common Stock of the Issuer outstanding as of June 30, 2019.

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SIGNATURES

After reasonable inquiry and to the best of its knowledge and belief, each of the undersigned certifies that the information set forth in this Schedule 13D/A is true, complete and correct.

Dated August 12, 2019

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