TRADE NEWS: Agilent Technologies Introduces Microarray for Rapid Screening of Aneuploidy in Single Cells from Embryos
January 12 2015 - 12:15PM
Business Wire
Total Time from Assay to Analysis Reduced to
Less Than Eight Hours
Agilent Technologies Inc. (NYSE: A) today introduced the
GenetiSure Pre-Screen Kit, a high-throughput oligonucleotide
microarray for screening aneuploidy and other genomic aberrations
in the 5- to 10-Mb range from single cells in three- and five-day
embryos.
Agilent’s kit allows for a turnaround time of less than eight
hours from DNA extraction to data analysis—an industry first. The
kit consists of a microarray that can run up to 14 samples and two
reference samples simultaneously, so more embryos can be screened
without significantly increasing costs.
“No other array platform currently has this high-throughput
capacity, with less than eight hours turn-around time, with this
resolution,” said Dr. Richard Choy, Ph.D., director of the
Pre-Implantation Genetic Diagnosis Center and associate professor
of the Department of Obstetrics and Gynecology at the Chinese
University of Hong Kong.
“We are cautious about the overall cost and value of our
screening,” Choy said. “We are able to use the capacity of
Agilent’s kit to address this price sensitivity, and it will
be key technology in our work.”
Agilent’s GenetiSure prescreen kit was developed based on a
protocol designed by Ali Hellani, Ph.D., director of the Viafet
Genomic Center in Dubai.
“Agilent’s microarray data can show small, few-megabase
microdeletions that are very difficult to detect at a single-cell
level,” Hellani said.
The GenetiSure Pre-Screen array is based on Agilent’s
market-leading technology for high-resolution oligonucleotide
comparative genomic hybridization. The kit contains all necessary
reagents to enable whole-genome amplification and labeling of
single cells. The microarray is compatible with Agilent’s
CytoGenomics software (version 3.0 or higher) for easy data
analysis.
To learn more about the GenetiSure Pre-Screen Kit, visit
www.agilent.com/genomics/genetisure/prescreen.
Agilent’s GenetiSure Pre-Screen Kit is for research use only,
not for use in diagnostic procedures.
About Agilent Technologies
Agilent Technologies Inc. (NYSE: A), a global leader in
life sciences, diagnostics and applied chemical markets, is the
premier laboratory partner for a better world. Agilent works with
customers in more than 100 countries, providing instruments,
software, services and consumables for the entire laboratory
workflow. Agilent generated revenues of $4.0 billion in fiscal
2014. The company employs about 12,000 people worldwide.
Information about Agilent is available at www.agilent.com.
NOTE TO EDITORS: Further technology, corporate citizenship and
executive news is available at www.agilent.com/go/news.
EDITORIAL CONTACT:for Agilent TechnologiesJennifer Mann, +1
303-357-2391jmann@webershandwick.com
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