RNS Number:1395R
Osmetech PLC
21 October 2003


                    BLOCKLISTING SIX MONTHLY REVIEW


1. NAME OF COMPANY:    OSMETECH PLC



2. NAME OF SCHEME:   OSMETECH PLC ENTERPRISE MANAGEMENT INCENTIVE PLAN



3. PERIOD OF RETURN:     FROM:  22/04/03      TO:  21/10/03



4. NUMBER AND CLASS OF SHARES(S)       46,873,595
   (AMOUNT OF STOCK/DEBT SECURITY)
   NOT ISSUED UNDER SCHEME
   AT END OF THE LAST PERIOD:



5. NUMBER OF SHARES ISSUED/ALLOTTED
   UNDER SCHEME DURING PERIOD:        3,825,000



6. BALANCE UNDER SCHEME NOT YET ISSUED/ALLOTTED 
   AT END OF PERIOD:      43,048,595



7. NUMBER AND CLASS OF SHARE(S) 
   (AMOUNT OF STOCK/DEBT SECURITIES)            17,123,595 ON 21/10/02
   ORIGINALLY LISTED AND THE DATE OF ADMISSION: 30,000,000 ON 11/3/03




                    BLOCKLISTING SIX MONTHLY REVIEW


1. NAME OF COMPANY:   OSMETECH PLC



2. NAME OF SCHEME:    INDIVIDUAL OPTION ARRANGEMENTS



3. PERIOD OF RETURN:     FROM:  22/04/03      TO:  21/10/03



4. NUMBER AND CLASS OF SHARES(S)      36,432,430
   (AMOUNT OF STOCK/DEBT SECURITY)
   NOT ISSUED UNDER SCHEME
   AT END OF THE LAST PERIOD:



5. NUMBER OF SHARES ISSUED/ALLOTTED
   UNDER SCHEME DURING PERIOD:        2,131,821



6. BALANCE UNDER SCHEME NOT YET ISSUED/ALLOTTED 
   AT END OF PERIOD:      34,300,609



7. NUMBER AND CLASS OF SHARE(S) 
   (AMOUNT OF STOCK/DEBT SECURITIES)              36,513,430 ON 21/10/02
   ORIGINALLY LISTED AND THE DATE OF ADMISSION:



                    BLOCKLISTING SIX MONTHLY REVIEW


1. NAME OF COMPANY:   OSMETECH PLC



2. NAME OF SCHEME:    PURSUANT TO THE EXERCISE OF WARRANTS BY GEM 



3. PERIOD OF RETURN:     FROM: 22/04/03     TO: 21/10/03



4. NUMBER AND CLASS OF SHARES(S)
   (AMOUNT OF STOCK/DEBT SECURITY)   1,030,000
   NOT ISSUED UNDER SCHEME
   AT END OF THE LAST PERIOD:



5. NUMBER OF SHARES ISSUED/ALLOTTED
   UNDER SCHEME DURING PERIOD:      0



6. BALANCE UNDER SCHEME NOT YET ISSUED/ALLOTTED 
   AT END OF PERIOD:       1,030,000



7. NUMBER AND CLASS OF SHARE(S) 
   (AMOUNT OF STOCK/DEBT SECURITIES)    1,030,000 ON 21/10/02
   ORIGINALLY LISTED AND THE DATE OF ADMISSION:



                    BLOCKLISTING SIX MONTHLY REVIEW


1. NAME OF COMPANY:   OSMETECH PLC



2. NAME OF SCHEME:    PURSUANT TO THE EXERCISE OF WARRANTS BY TRUE NORTH



3. PERIOD OF RETURN:     FROM:   22/04/03     TO:  21/10/03



4. NUMBER AND CLASS OF SHARES(S)
   (AMOUNT OF STOCK/DEBT SECURITY)    15,000,000
   NOT ISSUED UNDER SCHEME
   AT END OF THE LAST PERIOD:



5. NUMBER OF SHARES ISSUED/ALLOTTED
   UNDER SCHEME DURING PERIOD:       0



6. BALANCE UNDER SCHEME NOT YET ISSUED/ALLOTTED 
   AT END OF PERIOD:    15,000,000



7. NUMBER AND CLASS OF SHARE(S) 
   (AMOUNT OF STOCK/DEBT SECURITIES)    15,000,000 ON 21/10/02
   ORIGINALLY LISTED AND THE DATE OF ADMISSION:


CONTACT FOR QUERIES

NAME:        SALLY CRAIG
TELEPHONE:   020 7849 6027



                      This information is provided by RNS
            The company news service from the London Stock Exchange


END
BLREALEFASLDFFE