PTP Profile Thera.

RNS Number:8691A
Profile Therapeutics PLC
15 July 2004

LETTER TO:  PROFILE THERAPEUTICS PLC
            14 July 2004

Companies Act 1985 ("the Act") - Disclosure Of Interests In Shares

In accordance with sections 198 - 202 of the Act (as amended by the Companies
Act 1989 and the Disclosure of Interests In Shares (Amendment) Regulations 1993)
we hereby notify you that 3i Group plc has ceased to have a notifiable interest
in the Ordinary shares of 2p each in the share capital of your company.

From:  Pandora Sharp (Group Secretariat (3i))

                      This information is provided by RNS
            The company news service from the London Stock Exchange

END
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