Baylor Genetics Launches RNASeq Test for Whole Genome and Whole Exome Sequencing, Reduces Turnaround Times, Introduces Four New Genetic Analysis Panels
May 13 2024 - 8:00AM
Baylor Genetics, a clinical diagnostic laboratory at the forefront
of genetic testing, today announced the availability of a new RNA
sequencing test, RNAseq, for Whole Exome and Whole Genome
Sequencing (WES/WGS). The company also reduced its standard
turnaround time on WES and WGS to three weeks and continues to
provide rapid testing with written reports in as few as five days.
In addition, Baylor Genetics recently launched four new
next-generation sequencing panels for immunodeficiency, cerebral
palsy, connective tissue, and skeletal disorders.
New RNAseq Test
Baylor Genetics’ new RNAseq offering serves as a reflex from WGS
or WES after a qualified variant has been identified. By offering
insights into the impact of DNA variants on protein production, RNA
sequencing facilitates the resolution of Variants of Uncertain
Significance (VUS) and other qualified variants, ensuring quicker
and actionable diagnostic answers.
“Variants of unknown significance can be difficult for providers
to interpret, and may lengthen the diagnostic odyssey for
patients,” said Christine Eng, MD, Chief Medical Officer and Chief
Quality Officer at Baylor Genetics. "By enhancing our Whole Genome
and Whole Exome Sequencing tests with the addition of RNA
sequencing, we increase the potential to re-classify uncertain
variants and provide deeper understanding of a patient’s condition,
treatment options and health management.”
Baylor Genetics is able to advance the detection of certain
qualified VUS, using carefully curated genetic data, expert
interpretation, and prediction algorithm criteria. With the
addition of RNA Sequencing, 10-15% of qualified VUS are expected to
have a classification change and resolution. For qualifying cases,
the RNA sequencing test is performed as a reflex at no additional
charge to patients.
Whole Exome Sequencing (WES) and Whole Genome Sequencing (WGS)
are two of the most comprehensive DNA analyses in the market.
Although they can analyze most of the genome, inconclusive findings
are found with many patient results. RNA sequencing provides
additional context to these inconclusive results by taking analysis
a step further to predict protein effect, which can help determine
if a variant is likely to be associated with disease or
abnormality. With reduced turnaround time for standard WES and WGS
test results and the rapid 5 day option, answers can be provided
with high diagnostic yield and in timeframes that are among the
fastest in the industry.
New Specialized Panels
In a further expansion of its test menu, Baylor Genetics also
recently launched four panels, designed to target specific
categories of genetic disorders. The new Primary Immunodeficiency
Panel offers next-generation sequencing of 463 genes linked to rare
conditions and life-threatening problems with the immune system.
The Cerebral Palsy Spectrum Disorders Panel examines 419 genes
associated with motor development deficits. The Connective Tissue
Disorders Panel delves into 92 genes tied to multisystemic
conditions that affect soft connective tissues. The Skeletal
Disorders Panel reports on 354 genes related to skeletal
development and fragile bones.
To learn more, please visit https://www.baylorgenetics.com/.
About Baylor Genetics
A pioneer of precision medicine for over 40 years, Baylor
Genetics is a leading diagnostic genomics partner offering a full
spectrum of clinically relevant genetic testing, including Whole
Genome Sequencing, Whole Exome Sequencing, and focused panels. A
joint venture of H.U. Group Holdings, Inc. and Baylor College of
Medicine, which has the #1 NIH-funded Department of Molecular and
Human Genetics, Baylor Genetics couples the fastest and most
comprehensive precision diagnostics options with the support of
genetic counselors to help clinicians and their patients avoid a
lengthy diagnostic odyssey, guide medical management, and make sure
no patient with a genetic disorder gets left behind. Its test menu
spans from family planning, pregnancy, neonatal and pediatric
testing, oncology, and beyond.
Baylor Genetics is located in Houston’s Texas Medical Center and
serves clients in 50 states and 16 countries.
PR ContactSVM PRbaylorgenetics@svmpr.com(401)
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