MELBOURNE, Australia--U.S. biopharmaceutical company Celgene Corp. (CELG) agreed to buy a stake in Australian regenerative-medicine specialist Mesoblast Ltd. (MSB.AU) in a deal that also secures potential access to prospective treatments in a range of disease fields.

Celgene will buy 15.3 million shares in Mesoblast for 58.5 million Australian dollars (US$44.9 million), equal to A$3.82 a share, Mesoblast said Monday.

Celgene also will have a six-month right of first refusal to Mesoblast's mesenchymal lineage adult-stem-cell product candidates for the prevention and treatment of acute graft versus host disease, certain oncologic diseases, inflammatory bowel diseases, and organ transplant rejection.

Celgene, which focuses on the development of therapies for the treatment of cancer and immune-inflammatory related diseases, said the deal will bolster its pipeline of cellular and regenerative medicines.

Write to Robb M. Stewart at robb.stewart@wsj.com

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