PITTSBURGH, April 11, 2016 /PRNewswire/ -- At the 57th
Experimental Nuclear Magnetic Resonance Conference
(www.enc-conference.org), Bruker (NASDAQ: BRKR) is showcasing
several innovative drug discovery, drug development and process
control solutions for small molecule NMR characterization in the
chemical and pharmaceutical industries.
![Bruker's AssureNMR with CRAFT Bruker's AssureNMR with CRAFT](https://photos.prnewswire.com/prnvar/20160407/352781)
- AssureNMR with CRAFT: Now available with Complete
Reduction to Amplitude Frequency Table (CRAFT) and tools for
biologics analysis AssureNMR™ 2.1 reveals small structural
and compositional changes in complex materials such as biofluids,
culture media and biologics, important for product quality control.
CRAFT delivers matching and quantification of key metabolites,
based on targeted fingerprinting. Metabolite identification
is enhanced in AssureNMR by the ability to incorporate the
large, public Human Metabolome Data Base (HMDB) and DrugBank
database, each containing over 900 NMR spectra of metabolites and
drug compounds, respectively. Anthony Ribeiro, Ph.D., of
Duke University Medical Center said:
"These features represent major enhancements to the AssureNMR
software package for the detailed analysis of biofluid
systems." More …
- Experiment Selector: The latest release of
TopSpin® software, TS3.5pl6, features a
new, user-friendly GUI which provides easy access to vast
experiment libraries including standard Bruker pulse sequences and
user generated experiment libraries for both industrial and
academic users. The GUI enables users to build and organize their
own customized experiment libraries via simple drag and drop,
provides multiple options for experiment setup and optimization,
enables script based parameter adjustment, and makes the setup of
sophisticated experiments simple and efficient. More …
- Free TopSpin Processing: In order to provide
students, instructors and researchers with unlimited access to the
best tools for off-line NMR processing, Bruker is making their
market leading NMR processing software TopSpin available free of
charge for all academic users. In addition to Bruker NMR
data, the software is able to process data acquired on Agilent,
Varian and JEOL systems, and it can read data provided in JCAMP
format. For a download of TopSpin software, please go to:
www.bruker.com/TopSpin-Processing
- SmartDriveNMR: Bruker is setting new standards for
NMR solutions with its 'Intelligent NMR Spectrometer Initiative'.
The goal of this project is to incorporate automatic,
intelligent decision making into the spectrometer.
SmartDriveNMR – the further step in this direction – decides
on-the-fly for an optimized set of NMR experiments delivering the
most information with the best quality within a user defined
timeframe for a given spectroscopic problem.
SmartDriveNMR saves spectrometer time by
automatically running only these experiments that add the most
value to solve a given problem. SmartDriveNMR
is seamlessly integrated into the industry-standard routine NMR
acquisition software IconNMR to provide solutions for
structure consistency analysis, which are common in most NMR
service labs. More …
- Lab2NMR: This adaption of the automation and
scheduling system lab2labTM (www.ttplabtech.com)
allows NMR samples in modern, larger analytical service
organizations to be transported to the instrument via the lab2lab
pipe system. Samples are submitted for analysis directly from
the chemist's bench in standard vials. The lab2lab system
transports these vials to remote analytical NMR instrument via a
pipe system. Once at the instrument, lab2NMR accepts the
sample, prepares it for NMR measurement and schedules the
experiment. This system improves the efficiency and the
load-factor, thus enhancing NMR productivity. More …
- Dr. Harald Schröder at Novartis
Basel stated: "With the latest addition of Lab2NMR,
our well established lab2lab system for rapid, flexible and
hassle-free open access routine analytics became even more
productive. Now, chemists can send off samples for NMR
analysis as easily and with the same interface as they are used to
from LC-MS. The resulting spectra are in their inbox much
faster than previously, when the chemist had to find the closest
available open access system."
- New Automation Tools: The new SampleCase-heated
is designed for work in polymer research. It is capable of keeping
up to 24 samples at temperatures of up to 125°C, keeping polymers
liquid and ready for measurement. Bruker also announces the
next-generation cooling rack for the SampleJet
autosampler. This new module allows for individual cooling and
temperature regulation of each of the five sample racks. With the
additional 96 spinner-less open access sample positions, the
SampleJet is the best choice for metabolomics and
bio-screening applications. More …
- Bruker Fusion-SV 1.1: The new edition of the Bruker
Fusion-SV 1.1 automated structure verification solution for
small molecules in pharma and chemistry research integrates
high-resolution, accurate mass ESI-QTOF mass spectrometry for
automated chemical formula generation with NMR spectroscopy.
The updated Bruker Fusion-SV 1.1 solution now includes
additional 2D NMR methods for even higher confidence in rapid,
automated structure verification. Designed for the workflow
of medicinal and synthetic chemists in pharma, chemical industry or
in academia, Bruker Fusion-SV 1.1 guides chemists to
meaningful results with minimal interactions and without the need
for expert knowledge. More …
- InsightMR: Designed for the optimization of chemical
reactions under process conditions, the new
InsightMR™ solution uses on-line NMR monitoring to
enhance process understanding. InsightMR has a
new flow unit with temperature-controlled transfer lines to
enable fast and continuous transfer of reaction mixtures from a
vessel to the spectrometer. InsightMR software features a
user-friendly interface to allow both expert and non-expert NMR
users to set up experiments in deuterated and non-deuterated
solvents and optimize acquisition parameters on-the-fly, based on
real-time kinetic data. More…
- Fourier 300 HD: In 2010, Bruker introduced its
successful entry-level NMR system, the Fourier 300.
Based on the positive customer response, we now introduce an
improved version, the Fourier 300 HD. Derived from our
renowned Avance III HD electronics, the Fourier 300
HD provides an entry level, two-channel system for proton and
carbon operation for budget-conscious customers. The system
is equal in specifications to our Avance series and is operated by
TopSpin software. With its small footprint and freely
available TopSpin Processing software (limited to academic users),
the Fourier 300 HD is an excellent system for education and
smaller routine labs. More…
Werner E. Maas, Ph.D.,
President of the Bruker BioSpin
MRS Division, commented: "In addition to developing high
field magnets, such as our new Aeon 1 GHz magnet, and
new, highly sensitive X-nucleus direct detection
CryoProbes, we also focus our R&D on tools that
make our customers successful by enhancing their productivity or
expanding their range of NMR applications. In addition to
introductions for sample handling and data analysis, we started the
Intelligent NMR Spectrometer Initiative, a multi-year program to
enhance productivity and ease-of-use of our spectrometers.
SmartDriveNMR and lab2NMR are just two
of the early results of this program."
About Bruker Corporation
For more than 50 years, Bruker has enabled scientists to make
breakthrough discoveries and develop new applications that improve
the quality of human life. Bruker's high-performance
scientific research instruments and high-value analytical solutions
enable scientists to explore life and materials at molecular,
cellular and microscopic levels.
In close cooperation with our customers, Bruker is enabling
innovation, productivity and customer success in life science
molecular research, in applied and pharma applications, in
microscopy, nano-analysis and industrial applications, as well as
in cell biology, preclinical imaging, clinical research,
microbiology and molecular diagnostics. For more information,
please visit www.bruker.com.
For more information on Bruker at ENC 2016, please visit:
www.bruker.com/enc
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