ASILOMAR, Calif., March 27, 2017
/PRNewswire/ -- At the 58th Experimental Nuclear
Magnetic Resonance Conference (www.enc-conference.org), Bruker
announced new software and hardware addressing the need for
enhanced workflow solutions for NMR spectroscopy research and
analysis. These solutions will benefit researchers in many
disciplines of NMR, while providing productivity enhancements for
pharmaceutical users.
Rainer Kuemmerle, Ph.D., NMR
Product Manager for the Bruker BioSpin Magnetic Resonance
Spectroscopy division, explained: "We always have our customers in
mind when developing new technologies and applications, and these
latest NMR solutions exemplify this mindset. From academic, to
pharma, and to chemical and advanced materials customers, we
focus on making our customers successful by enhancing their
productivity and expanding their range of NMR applications."
New Software
TopSpin 4® is the next generation of Bruker's
NMR software for spectrometer control and data analysis, designed
for the newly introduced AVANCE™ NEO platform. The
combination of a new user interface and capabilities to support
multiple receivers and other AVANCE NEO capabilities, will
make TopSpin 4 a very powerful and intuitive software for
NMR spectroscopists. Existing AVANCE III HD customers will
also benefit from a new TopSpin 3.5 version, as we continue
enhancements and support for the Avance III HD platform.
Designed to simplify and accelerate the setup of biomolecular
NMR experiments, the new bioTop™ module performs most
biomolecular tasks in full automation. Only minimal user
interaction is required for most experiments. The process starts
after inserting the sample, taking care of shimming, locking and
tuning if necessary. From experiment selections to final processed
spectra, including optimization of commonly used parameters,
bioTop can be customized to accommodate much of the
workflow in biomolecular NMR laboratories.
The new TopSolids™ module is an intuitive,
workflow-based software for solid-state NMR.
TopSolids is designed to give easy access to the
delicate setup of probe hardware and complex solid-state NMR
experiments, e.g. from structural biology on membrane proteins, to
pharmaceutical comounds, to
catalysis, battery research, polymer or material science
work. For any customer who could benefit from solid-state
NMR, TopSolids 2.0 will be a great productivity tool,
decreasing the time for setup and providing even more results, for
novice and expert users.
Of particular interest to BioTech and Pharma customers are two
novel solutions:
Bruker's new PotencyMR™ solution provides a
cost-effective 'one-stop' NMR approach for determining the potency
of drugs, including potency calculation, identification, residual
solvent and water content in one single experiment. With a
streamlined, easy-to-use, robust workflow from sample submission to
report, PotencyMR is for experts and non-experts in
pharmaceutical development, where quality, accuracy and
reproducibility are required.
NMR Fragment-based Screening (FBS)
in the pharmaceutical industry has become a widely applied method
for the discovery and optimization of lead molecules in targeted
screening campaigns. The new FBS workflow solution is
built into TopSpin® and streamlines FBS
data handling and analysis, thus providing an easier way to screen
compounds to find potential new drugs.
For NMR detection, Bruker is pleased to introduce the new
iProbe™ platform. This novel NMR probe
architecture allows not only for an increase in signal to noise,
and faster and more accurate rf tuning, but also provides a more
flexible design that allows easier customization of NMR probes for
dedicated applications. The first probes introduced on this
platform include the industry-leading SmartProbe
iProbes, available now from 400-600 MHz, offering up to 10%
increase in sensitivity.
The InsightMR™ portfolio of applications for
monitoring chemical and biological processes is expanding further,
in order to increase understanding of reaction mechanisms,
chemical processes as well as cell metabolism.
InsightXpress™ now enhances the NMR monitoring of
fast reactions and rapid, automated, screening of reactions
conditions. For studies on living cells, InsightCell™
now monitors living cells to study their biological activity
through direct NMR measurements of variations in metabolite
concentration.
About Bruker Corporation (NASDAQ: BRKR)
For more than
55 years, Bruker has enabled scientists to make breakthrough
discoveries and develop new applications that improve the quality
of human life. Bruker's high-performance scientific
instruments and high-value analytical and diagnostic solutions
enable scientists to explore life and materials at molecular,
cellular and microscopic levels. In close cooperation with
our customers, Bruker is enabling innovation, productivity and
customer success in life science molecular research, in applied and
pharma applications, in microscopy, nano-analysis and industrial
applications, as well as in cell biology, preclinical imaging,
clinical phenomics and proteomics research, clinical microbiology
and molecular pathology research. For more information,
please visit: www.bruker.com
Media
Contact:
|
Investor
Contact:
|
Thorsten Thiel,
Ph.D.
|
Miroslava
Minkova
|
VP of Group
Marketing
|
Head of Investor
Relations
|
Bruker BioSpin
Group
|
Bruker
Corporation
|
T: +49 (721)
5161–6500
|
T: +1 (978) 663-3660,
ext. 1479
|
E:
thorsten.thiel@bruker.com
|
E:
miroslava.minkova@bruker.com
|
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SOURCE Bruker Corporation