Express Scripts Inc. (ESRX) agreed to buy Medco Health Solutions Inc. (MHS) for $29.1 billion in cash and stock, linking together two of the nation's largest pharmacy-benefit managers at a time one of them faces losing its biggest customer.

By joining forces, Express Scripts and Medco will become the largest PBM with nearly a third of the market. They aim to leverage their new-found heft to lower the cost of prescription drugs--indicating more pressure on pharmaceutical companies at a time they're already facing the loss of patent protection for top products.

"The cost and quality of healthcare is a great concern to all Americans; this is the right deal at the right time for the right reasons," said Express Scripts Chief Executive George Paz, 55 years old, who will lead the combined company. PBMs help employers and health-insurance companies administer prescription-drug benefits, process claims and control drug costs by securing discounts from drug makers.

Medco--larger than Express Scripts by revenue but smaller by market capitalization--also confirmed its deal with managed-care giant UnitedHealth Group Inc. (UNH) won't be renewed when the current contract expires after next year. UnitedHealth, which represents 17% of Medco's sales, is expected to run that business itself.

Medco holders will receive $28.80 in cash and 0.81 Express Scripts shares for each share, valuing Medco at $71.36, a 28% premium to Wednesday's close. In premarket trading Thursday, Medco continued to trade below the offer price. The deal--based on ESRX trading at $56.25, up 7%--values MHS at $74.36 a share. MHS shares are trading at $66.75, up 20%.

After the deal closes, Express Scripts shareholders are expected to own about 59% of the combined company, and Medco shareholders will have the remainder. The combined company will be headquartered in St. Louis, where Express Scripts is now.

The companies expect the deal to create $1 billion in synergies and close by first half of 2012, although it could face antitrust scrutiny.

The regulatory review "may be challenging," Sanford Bernstein analyst Helene Wolk said, but the industry's competitive intensity, plus the emergence of UnitedHealth's business, "improve the likelihood of approval." CVS Caremark Corp. (CVS) is the other major pharmacy-benefit manager and has about 21% of the market, Wolk said.

In their merger press release, the companies emphasized that the deal would help lower drug costs and create a more efficient healthcare system, possibly an indication of their argument against the antitrust concerns.

Medco has faced intense speculation for the past couple months that UnitedHealth could end its relationship with Medco in favor of its own internal pharmacy-benefit manager, known as OptumRx. UnitedHealth didn't have a decision to announce on its earnings call Tuesday, though Chief Executive Stephen Hemsley said the company continued to assess its options and opportunities.

But Medco confirmed Thursday that "after several months of discussions, its pharmacy benefit services agreement with UnitedHealthcare would not be renewed." Medco will continue serving the health insurer through the expiration of the current agreement at the end of next year.

While the catalyst for the Express Scripts/Medco deal is "ultimately offensive," it's "initially defensive," Barclays analyst Larry Marsh said. He noted Medco's UnitedHealth loss plus Express Scripts "weaker-than-expected scripts" for the second quarter.

There has already been consolidation in the pharmacy-benefit management industry. Express Scripts officials have publicly said in the last year that the company was on the hunt for acquisitions. In 2009, it acquired the prescription unit of WellPoint Inc. (WLP), a health insurer, in a $4.7 billion deal.

In 2007, Express Scripts lost out on acquiring rival Caremark Rx to drug store giant CVS, which acquired Caremark for about $26 billion. At that time, Medco was seen as a possible next target for Express Scripts. Express Scripts, which employs about 13,000 people, also distributes injectible biopharmaceutical products to patients or doctors, and provides cost-management and patient-care services.

Medco, spun out of drug giant Merck & Co. in 2003, provides clinical research and pharmacy services aimed at improving care while reducing health-care costs for private and public employers, union and government agencies. The company took in $66 billion in 2010 net revenue.

Express Scripts reported its second-quarter earnings climbed 15% to $334.2 million, or 66 cents a share. Excluding items, per-share earnings were 71 cents. Revenue edged up 0.6% to $11.36 billion.

Meanwhile, Medco reported its earnings fell 4% to $342.8 million, or 85 cents a share. Excluding writedowns, per-share earnings rose to 96 cents from 87 cents. Revenue jumped 4.1% to $17.07 billion.

The advisers for Express Scripts are Credit Suisse Group AG (CS), Citigroup Inc. (C) and law firm Skadden, Arps, Slate, Meagher & Flom, LLP. Medco is advised by J.P. Morgan Chase & Co. (JPM), Lazard Ltd. (LAZ), and law firms Sullivan & Cromwell LLP and Dechert LLP.

This deal is the second-largest announced this year, after AT&T Inc.'s (T) planned purchase of T-Mobile USA from Deutsche Telekom AG (DTEGY, DTE.XE).

-By Jon Kamp, Dow Jones Newswires; 617-654-6728; jon.kamp@dowjones.com

--Anupreeta Das, Gina Chon, Anna Wilde Mathews, Nathalie Tadena and Lauren Pollock contributed to this story.

Medco (NYSE:MHS)
Historical Stock Chart
From Jun 2024 to Jul 2024 Click Here for more Medco Charts.
Medco (NYSE:MHS)
Historical Stock Chart
From Jul 2023 to Jul 2024 Click Here for more Medco Charts.