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| Holder | Type | Held (Actual) | % of Outstanding | Market Value | Date Reported |
|---|---|---|---|---|---|
| BVF Partners L.P. | Institution | 9,888,592 | 26.36% | US$ 37.58M | 2026-03-31 |
| Biotechnology Value Fund L.P. | Institution | 5,077,491 | 13.54% | US$ 19.29M | 2025-12-31 |
| Suvretta Capital Management, LLC | Institution | 4,284,806 | 11.42% | US$ 16.28M | 2026-03-31 |
| Averill Master Fund, Ltd. | Institution | 4,284,806 | 11.42% | US$ 16.28M | 2025-12-31 |
| Biotechnology Value Fund II, L.P. | Institution | 4,102,563 | 10.94% | US$ 15.59M | 2025-12-31 |
| UBS Asset Management AG | Institution | 2,054,216 | 5.48% | US$ 7.81M | 2026-03-31 |
| GAM Holding AG | Institution | 956,758 | 2.55% | US$ 3.64M | 2025-12-31 |
| Biotechnology Value Trading Fund OS LP | Institution | 514,365 | 1.37% | US$ 1.95M | 2025-12-31 |
| Acatis Anlageberatung fur Investmentfonds GmbH | Institution | 200,000 | 0.53% | US$ 760.00k | 2025-04-30 |
| Fourton Fund Management Co. Ltd | Institution | 123,946 | 0.33% | US$ 470.99k | 2025-06-30 |
| BlackRock, Inc. | Institution | 98,117 | 0.26% | US$ 372.84k | 2026-05-31 |
| LLB Asset Management AG | Institution | 63,005 | 0.17% | US$ 239.42k | 2025-09-30 |
| Swiss Life Asset Management AG | Institution | 31,547 | 0.08% | US$ 119.88k | 2025-03-31 |
| SmartHarvest Portfolios LLC | Institution | 15,543 | 0.04% | US$ 59.06k | 2026-03-31 |
| Dimensional Fund Advisors LP | Institution | 14,653 | 0.04% | US$ 55.68k | 2026-04-30 |
| Pictet Asset Management Limited | Institution | 10,246 | 0.03% | US$ 38.93k | 2025-09-30 |
| State Street Global Advisors, Inc. | Institution | 9,207 | 0.02% | US$ 34.99k | 2026-04-30 |
| Union Bancaire Privée, UBP SA | Institution | 6,661 | 0.02% | US$ 25.31k | 2025-06-30 |
| Migrosbank Asset Management | Institution | 3,003 | 0.01% | US$ 11.41k | 2025-06-30 |
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