Crystal Research Associates, LLC Issues Executive Informational Overview(R) (EIO(R)) on Advaxis, Inc.
April 28 2008 - 8:30AM
PR Newswire (US)
NEW YORK, April 28 /PRNewswire/ -- Crystal Research Associates, LLC
announced today that it has issued an Executive Informational
Overview(R) (EIO(R)) on Advaxis, Inc. (OTC:ADXS) (BULLETIN BOARD:
ADXS) . The full 60-page report can be found at
http://www.crystalra.com/. Advaxis, Inc. ("Advaxis" or "the
Company") uses live, genetically modified Listeria monocytogenes
("Listeria") to safely create vaccines that stimulate multiple
immune responses against cancer as well as infectious and immune
disorders. Through patented techniques, the Company engineers the
Listeria bacteria to secrete a specific antigen. The recipients'
immune system recognizes and processes that antigen in order to
provoke an immune attack against the cancer. Advaxis' Listeria
platform technology is licensed from the University of
Pennsylvania, where it has been developed over the past 15 years by
Dr. Yvonne Paterson, the scientific founder of the Company and
current chair of its Scientific Advisory Board. At present, Advaxis
is engineering Listeria to fight cervical intraepithelial neoplasia
("CIN") and cervical, head and neck, prostate, breast, and other
cancers. The cancer vaccine market is forecast to reach over $8
billion by 2012, up from $481 million in 2007. In preclinical
studies, Listeria-based cancer vaccines have a 100% therapeutic
response rate and consistently provoke tumor regression, completely
eliminating tumors in over 50% of mice. Moreover, animals dosed
with these vaccines show a long-term immunity against cancer, with
new tumor cells unable to grow. This suggests that the technology
can not only treat existing tumors but may also prevent cancer
recurrence. In 2007, Advaxis completed its first human clinical
trial of the Listeria platform using Lovaxin C, a vaccine for human
papillomavirus (HPV)-derived cervical cancer. In the Phase I trial,
the vaccine has been shown to be safely administered to humans and
well tolerated. To Advaxis' knowledge, it is the first entity to
safely administer live Listeria as an antigen carrier and immune
system stimulant in humans. A Phase II clinical trial is planned
for patients with CIN I/II in 2008. About Crystal Research
Associates, LLC Crystal Research Associates, LLC is an independent
research firm that provides institutional-quality, fee-based
research to small and mid-cap companies. Crystal Research
Associates' unique and novel product, the Executive Informational
Overview(R) (EIO(R)), is free of investment ratings, target prices,
and forward-looking financial models. The EIO(R) presents a crystal
clear, detailed report on a company (public or private) in a manner
that is easily understood by the Wall Street financial community.
The EIO(R) details a company's product/technology/service
offerings, market size(s), key intellectual property, leadership,
growth strategy, competition, risks, audited financial statements,
key events, and other such fundamental information. Crystal
Research Associates has offices in New York City and Delray Beach.
Crystal Research Associates has been compensated by the Company in
cash of forty thousand U.S. dollars and four hundred thousand
four-year Options/Warrants to purchase Advaxis' stock for its
services in creating this report, for updates, and for printing
costs. Forward-Looking Safe Harbor Statement Statements in this
news release regarding future financial and operating results,
potential applications of the Company's technology, opportunities
for the Company, and any other statements about the future
expectations, beliefs, goals, plans, or prospects expressed
constitute forward-looking statements within the meaning of the
Private Securities Litigation Reform Act of 1995. Any statements
that are not statements of historical fact (including statements
containing the words "will," "believes," "plans," "anticipates,"
"expects," "estimates," and similar expressions) should also be
considered to be forward-looking statements. There are a number of
important factors that could cause actual results or events to
differ materially from those indicated by such forward-looking
statements including, limited operating history, need for future
capital, and economic conditions generally. Additional information
on potential factors that could affect results and other risks and
uncertainties are detailed from time to time in the Company's
periodic reports, including forms filed with SEC. These statements,
and other forward-looking statements, are not guarantees of future
performance and involve risks and uncertainties. Crystal Research
Associates assumes no obligation to update any of the
forward-looking statements in this release. DATASOURCE: Crystal
Research Associates, LLC CONTACT: Jeffrey J. Kraws, , or Karen B.
Goldfarb, , both of Crystal Research Associates, LLC,
+1-609-306-2274, fax, +1-609-395-9339 Web site:
http://www.crystalra.com/
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