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UNITED
STATES
SECURITIES
AND EXCHANGE COMMISSION
Washington,
D.C. 20549
FORM
10-Q
(Mark
One)
☒
QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
For
the quarterly period ended: June 30, 2023, or
☐
TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
For
the transition period from to
Commission
File Number: 001-41575
Lipella
Pharmaceuticals Inc.
(Exact
name of registrant as specified in its charter)
Delaware |
|
20-2388040 |
(State or other jurisdiction
of
incorporation or organization) |
|
(I.R.S. Employer
Identification No.) |
7800
Susquehanna St., Suite 505 |
Pittsburgh,
PA 15208 |
(Address
of principal executive offices) (Zip Code)
|
(412)
901-0315 |
(Registrant’s
telephone number, including area code) |
Securities
registered pursuant to Section 12(b) of the Act
Title
of each class |
|
Trading
Symbol(s) |
|
Name
of exchange on which registered |
Common Stock, par
value $0.0001 per share |
|
LIPO |
|
Nasdaq Capital Market |
Indicate
by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange
Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports),
and (2) has been subject to such filing requirements for the past 90 days. Yes ☒ No ☐
Indicate
by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant
to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or such shorter period that the
registrant was required to submit such files). Yes ☒ No ☐
Indicate
by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting
company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,”
“smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.
Large accelerated filer |
☐ |
Accelerated filer |
☐ |
Non-accelerated filer |
☒ |
Smaller reporting company |
☒ |
|
|
Emerging growth company |
☒ |
If
an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for
complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.
Indicate
by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes ☐ No ☒
As of August 11, 2023,
there were 5,743,945 shares of common stock, par value $0.0001 per share, of the registrant outstanding.
Lipella
Pharmaceuticals Inc.
Form
10-Q
June
30, 2023
Table
of Contents
References in this Quarterly
Report on Form 10-Q to the “Company,” “Lipella,” “we,” “us,” or “our”
mean Lipella Pharmaceuticals Inc. unless otherwise expressly stated or the context indicates otherwise.
PART
I. FINANCIAL INFORMATION
Item
1. Financial Statements.
Lipella
Pharmaceuticals Inc.
CONDENSED
BALANCE SHEETS
|
|
June
30, 2023
(unaudited) |
|
|
December
31, 2022 |
|
Assets |
|
|
|
|
|
|
Current Assets |
|
|
|
|
|
|
|
|
Cash
and cash equivalents |
|
$ |
3,113,644 |
|
|
$ |
5,121,743 |
|
Grants receivable |
|
|
28,044 |
|
|
|
113,655 |
|
Prepaid
expenses |
|
|
225,302 |
|
|
|
563,891 |
|
Total Current Assets |
|
|
3,366,990 |
|
|
|
5,799,289 |
|
Operating lease
right of use asset |
|
|
122,546 |
|
|
|
150,821 |
|
Total
Assets |
|
$ |
3,489,536 |
|
|
$ |
5,950,110 |
|
Liabilities and Stockholders' Equity |
|
|
|
|
|
|
|
|
Current liabilities |
|
|
|
|
|
|
|
|
Accounts payable |
|
$ |
22,057 |
|
|
$ |
384,357 |
|
Accrued expenses |
|
|
138,704 |
|
|
|
389,209 |
|
Operating lease liability |
|
|
60,788 |
|
|
|
58,262 |
|
Payroll liability |
|
|
77,255 |
|
|
|
67,832 |
|
Notes payable, current |
|
|
— |
|
|
|
25,000 |
|
Related party loan |
|
|
— |
|
|
|
250,000 |
|
Related
party interest |
|
|
— |
|
|
|
3,596 |
|
Total Current Liabilities |
|
|
298,804 |
|
|
|
1,178,256 |
|
Operating lease
liability, net of current portion |
|
|
65,390 |
|
|
|
96,258 |
|
Total
Liabilities |
|
|
364,194 |
|
|
|
1,274,514 |
|
Stockholders' equity: |
|
|
|
|
|
|
|
|
Preferred
stock, $0.0001 par value; 20,000,000 shares authorized; 0 shares outstanding at June 30, 2023 and December
31, 2022 |
|
$ |
— |
|
|
$ |
— |
|
Common
stock, $0.0001
par value; 200,000,000
shares authorized; 5,743,945 shares issued and outstanding at June 30, 2023 and December 31, 2022 |
|
|
574 |
|
|
|
574 |
|
Additional paid-in capital |
|
|
11,436,157 |
|
|
|
10,379,900 |
|
Accumulated deficit |
|
|
(8,311,389 |
) |
|
|
(5,704,878 |
) |
Total
stockholders' equity |
|
|
3,125,342 |
|
|
|
4,675,596 |
|
Total
liabilities and stockholders' equity |
|
$ |
3,489,536 |
|
|
$ |
5,950,110 |
|
On
December 19, 2022, a reverse stock split (the “Stock Split”) was effected, with a 2.5 to 1 share conversion ratio
for all shares of our common stock, $0.0001 par value per share (“Common Stock”), outstanding. All per share amounts
have been retroactively adjusted to reflect the effects of the Stock Split. See Note 11 for more information. The
accompanying notes are an integral part of these condensed financial statements.
Lipella
Pharmaceuticals Inc.
CONDENSED
STATEMENTS OF OPERATIONS
(Unaudited)
| |
| | |
| | |
| | |
| |
| |
For
the three months ended | | |
For
the six months ended | |
| |
June
30, 2023 | | |
June
30, 2022 | | |
June
30, 2023 | | |
June
30, 2022 | |
Grant
revenues | |
$ | 106,676 | | |
$ | — | | |
$ | 224,724 | | |
$ | 33,149 | |
Total
revenues | |
| 106,676 | | |
| — | | |
| 224,724 | | |
| 33,149 | |
| |
| | | |
| | | |
| | | |
| | |
Cost
and expenses | |
| | | |
| | | |
| | | |
| | |
Research
and development | |
| 1,057,645 | | |
| 742,660 | | |
| 1,751,376 | | |
| 1,418,622 | |
General
and administrative | |
| 624,231 | | |
| 38,487 | | |
| 1,132,980 | | |
| 132,337 | |
Total
costs and expenses | |
| 1,681,876 | | |
| 781,147 | | |
| 2,884,356 | | |
| 1,550,959 | |
Loss
from operations | |
| (1,575,200 | ) | |
| (781,147 | ) | |
| (2,659,632 | ) | |
| (1,517,810 | ) |
| |
| | | |
| | | |
| | | |
| | |
Other
income (expense) | |
| | | |
| | | |
| | | |
| | |
Other
income (expense) | |
| — | | |
| 156 | | |
| — | | |
| (45 | ) |
Interest
income | |
| 41,968 | | |
| 603 | | |
| 63,969 | | |
| 1,134 | |
Interest
expense related party | |
| (5,454 | ) | |
| (1,636 | ) | |
| (10,848 | ) | |
| (3,254 | ) |
Total
other income/(expense) | |
| 36,514 | | |
| (877 | ) | |
| 53,121 | | |
| (2,165 | ) |
Provision
for income taxes | |
| — | | |
| — | | |
| — | | |
| — | |
Net
Loss | |
$ | (1,538,686 | ) | |
$ | (782,024 | ) | |
$ | (2,606,511 | ) | |
$ | (1,519,975 | ) |
| |
| | | |
| | | |
| | | |
| | |
Loss
per share of Common Stock
| |
| | | |
| | | |
| | | |
| | |
Basic | |
| (0.27 | ) | |
| (0.20 | ) | |
| (0.45 | ) | |
| (0.39 | ) |
Dilutive | |
| (0.27 | ) | |
| (0.20 | ) | |
| (0.45 | ) | |
| (0.39 | ) |
| |
| | | |
| | | |
| | | |
| | |
Weighted-average
of shares of Common Stock outstanding:
| |
| | | |
| | | |
| | | |
| | |
Basic | |
| 5,743,945 | | |
| 3,866,625 | | |
| 5,743,945 | | |
| 3,866,625 | |
Dilutive | |
| 5,743,945 | | |
| 3,866,625 | | |
| 5,743,945 | | |
| 3,866,625 | |
All
per share amounts have been retroactively adjusted to reflect the effects of the Stock Split. See Note 11 for more information.
The accompanying notes are an integral part of these condensed financial statements.
Lipella
Pharmaceuticals Inc.
CONDENSED
STATEMENTS OF CHANGES IN STOCKHOLDERS’ EQUITY
(Unaudited)
| |
| | | |
| | | |
| | | |
| | | |
| | |
| | |
| | |
| |
Series
A Convertible Preferred Stock | | |
Common
Stock | | |
Additional
paid-in | | |
Accumulated | | |
| | |
| |
Shares | | |
Amount | | |
Shares | | |
Amount | | |
capital | | |
Deficit | | |
Total | |
Balances,
December 31, 2021 | |
| 1,592,447 | | |
$ | 159 | | |
| 3,866,625 | | |
$ | 387 | | |
$ | 4,530,193 | | |
$ | (3,107,187 | ) | |
$ | 1,423,552 | |
Net
loss | |
| — | | |
| — | | |
| — | | |
| — | | |
| — | | |
| (737,950 | ) | |
| (737,950 | ) |
Issuance
of stock options | |
| — | | |
| — | | |
| — | | |
| — | | |
| 235,148 | | |
| — | | |
| 235,148 | |
Balances,
March 31, 2022 | |
| 1,592,447 | | |
| 159 | | |
| 3,866,625 | | |
| 387 | | |
| 4,765,341 | | |
| (3,845,137 | ) | |
| 920,750 | |
Net
loss | |
| — | | |
| — | | |
| — | | |
| — | | |
| — | | |
| (782,024 | ) | |
| (782,024 | ) |
Issuance
of stock options | |
| — | | |
| — | | |
| — | | |
| — | | |
| 213,489 | | |
| — | | |
| 213,489 | |
Balances,
June 30, 2022 | |
| 1,592,447 | | |
| 159 | | |
| 3,866,625 | | |
| 387 | | |
| 4,978,830 | | |
| (4,627,161 | ) | |
| 352,215 | |
| |
| | | |
| | | |
| | | |
| | | |
| | | |
| | | |
| | |
Balances,
December 31, 2022 | |
| — | | |
| — | | |
| 5,743,945 | | |
| 574 | | |
| 10,379,900 | | |
| (5,704,878 | ) | |
| 4,675,596 | |
Net
loss | |
| — | | |
| — | | |
| — | | |
| — | | |
| — | | |
| (1,067,825 | ) | |
| (1,067,825 | ) |
Issuance
of stock options | |
| — | | |
| — | | |
| — | | |
| — | | |
| 208,639 | | |
| — | | |
| 208,639 | |
Balances,
March 31, 2023 | |
| — | | |
| — | | |
| 5,743,945 | | |
| 574 | | |
| 10,588,539 | | |
| (6,772,703 | ) | |
| 3,816,410 | |
Net
loss | |
| — | | |
| — | | |
| — | | |
| — | | |
| — | | |
| (1,538,686 | ) | |
| (1,538,686 | ) |
Issuance
of stock options | |
| — | | |
| — | | |
| — | | |
| — | | |
| 847,618 | | |
| — | | |
| 847,618 | |
Balances,
June 30, 2023 | |
| — | | |
| — | | |
| 5,743,945 | | |
| 574 | | |
| 11,436,157 | | |
| (8,311,389 | ) | |
| 3,125,342 | |
All
per share amounts have been retroactively adjusted to reflect the effects of the Stock Split. See Note 11 for more information.
The accompanying notes are an integral part of these condensed financial statements.
Lipella
Pharmaceuticals Inc.
CONDENSED
STATEMENTS OF CASH FLOWS
(Unaudited)
| |
|
|
|
|
|
| |
| |
For the six months ended | |
| |
June 30, | |
| |
2023 | | |
2022 | |
Cash flow from operating activities: | |
| | | |
| | |
Net loss | |
$ | (2,606,511 | ) | |
$ | (1,519,975 | ) |
Adjustments to reconcile net loss to net cash
provided by (used in) operating activities: | |
| | | |
| | |
Non-cash stock option expense | |
| 1,056,257 | | |
| 448,637 | |
Interest expense related party net (non-cash) | |
| — | | |
| 3,254 | |
Changes in operating assets and liabilities: | |
| | | |
| | |
Operating right of use asset | |
| (67 | ) | |
| 582 | |
Grants receivable | |
| 85,611 | | |
| — | |
Prepaid expense | |
| 338,589 | | |
| (368,334 | ) |
Accounts payable | |
| (362,300 | ) | |
| 8,583 | |
Accrued expenses | |
| (254,101 | ) | |
| 146,918 | |
Payroll liability | |
| 9,423 | | |
| 944 | |
Net cash used in operating activities | |
| (1,733,099 | ) | |
| (1,279,391 | ) |
Cash flow from investing activities: | |
| | | |
| | |
Net cash provided by investing activities | |
| — | | |
| 300,546 | |
Cash flow from financing activities: | |
| | | |
| | |
Repayment of notes payable | |
| (275,000 | ) | |
| — | |
Net cash used in financing activities | |
| (275,000 | ) | |
| — | |
Net decrease in cash, cash equivalents | |
| (2,008,099 | ) | |
| (978,845 | ) |
Cash, and cash equivalents at beginning of period | |
| 5,121,743 | | |
| 1,413,828 | |
Cash, and cash equivalents at end of period | |
$ | 3,113,644 | | |
$ | 434,983 | |
| |
| | | |
| | |
Supplemental disclosure of cash flow information: | |
| | | |
| | |
Interest Paid | |
| (10,338 | ) | |
| — | |
Income taxes paid | |
| — | | |
| — | |
Supplemental disclosure of cash flow information: | |
| | | |
| | |
Issuance of Common Stock for forgiveness of related party note | |
$ | — | | |
$ | — | |
Exercise of Common Stock options for consulting services | |
$ | — | | |
$ | — | |
All
per share amounts have been retroactively adjusted to reflect the effects of the Stock Split. See Note 11 for more information.
The accompanying notes are an integral part of these condensed financial statements.
Lipella Pharmaceuticals Inc.
NOTES TO
CONDENSED FINANCIAL STATEMENTS
(Unaudited)
Note 1. Description of Business and Basis of Presentation
Nature of Business
Lipella Pharmaceuticals Inc. (the “Company”) is focused on the development of drugs, diagnostics,
and medical devices. Our operations consist of research, preclinical development and clinical development activities, and our most
advanced program is in Phase 2a clinical development. Since our inception in 2005, we have historically financed our operations
through a combination of federal grant revenue, licensing revenue, manufacturing revenue, as well as equity and debt financing.
The Company is located in Pittsburgh, PA. On December 19, 2022, we effected the Stock Split. The Company’s outstanding
share and per share amounts in these condensed financial statements have been adjusted to give effect to the Stock Split, for all periods
presented. For more information, see Note 11 - Common Stock.
Basis of Presentation
The
Company’s unaudited condensed financial statements have been prepared in accordance with U.S. generally accepted accounting
principles (“GAAP”). Any reference in these notes to applicable guidance is meant to refer to the authoritative GAAP
as found in the Accounting Standards Codification (“ASC”) and Accounting Standards Updates (“ASU”) of the
Financial Accounting Standards Board (“FASB”).
In the opinion of management,
the accompanying unaudited condensed financial statements include all adjustments, consisting of normal recurring
adjustments, which are necessary to present fairly the Company’s financial position, results of operations, and cash flows.
The interim results of operations are not necessarily indicative of the results that may occur for the full fiscal year. Certain
information and footnote disclosure normally included in the financial statements prepared in accordance with GAAP have been condensed
or omitted pursuant to instructions, rules, and regulations prescribed by the United States Securities and Exchange Commission
(“SEC”). The unaudited condensed interim financial statements should be read in conjunction with the audited financial statements
and notes thereto included in our Annual Report on Form 10-K for the year ended December 31, 2022 that was filed with
the SEC on March 31, 2023 (our “Annual Report”).
Note 2. Going Concern
The accompanying condensed financial
statements have been prepared in conformity with GAAP, which contemplate continuation of the Company as a going concern. The Company
has not established a source of revenues sufficient to cover its operating costs and will require significant additional capital
to continue its research and development programs, including progressing clinical product candidates to commercialization and
preparing for commercial-scale manufacturing and sales.
The Company’s net loss
for the six months ended June 30, 2023 and fiscal year ended December 31, 2022 was ($2,606,511) and ($2,597,692), respectively.
Since inception, the Company has incurred historical losses and has an accumulated deficit of ($8,311,389) at June 30, 2023 and
($5,704,878) at December 31, 2022, respectively. At June 30, 2023, the Company had available cash and cash equivalents of $3,113,644
and net working capital of $3,068,186. The Company anticipates operating losses to continue for the foreseeable future
due to, among other things, costs related to: research, development of product candidates, conducting preclinical studies
and clinical trials, and administrative organization. These funds, and our funds available under existing government contracts,
may not be sufficient to enable us to meet our obligations as they come due at least for the next twelve months from the issuance
date of these financial statements.
If we are unable to
obtain additional capital (which is not assured at this time), our long-term business plan may not be accomplished and we may be
forced to curtail or cease operations. These factors individually and collectively raise substantial doubt about our ability to
continue as a going concern. The accompanying unaudited condensed financial statements do not include any adjustments that may result from this uncertainty.
Note 3. Summary of Significant Accounting Policies
Use of Estimates
The preparation of
financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts
of assets and liabilities and disclosure of contingent assets and liabilities at the date of these financial statements. Actual
results could differ from those estimates.
Basis of Presentation
The unaudited condensed
financial statements have been prepared in accordance with GAAP for interim financial information and Article 10 of Regulation
S-X. Accordingly, the unaudited condensed financial statements do not include all of the information and footnotes required by
GAAP for complete financial statements and should be read in conjunction with the Company’s audited financial statements
and notes thereto included in our Annual Report.
Marketable Debt Securities
Marketable debt securities
consist of debt investments with original maturities greater than three months. The Company classifies its marketable debt securities
as available-for-sale. Accordingly, these investments are recorded at fair value, which is based on quoted market prices. When
the fair value is below the amortized cost the amount of the expected credit loss is estimated. The credit-related impairment amount
is recognized in net income; the remaining impairment amount and unrealized gains are reported as a component of accumulated other
comprehensive income in stockholders’ equity. Credit losses are recognized through the use of an allowance for credit losses
account and subsequent improvements in expected credit losses are recognized as a reversal of the allowance account. If the Company
has the intent to sell the security or if it is more likely than not that the Company will be required to sell the security prior
to recovery of its amortized cost basis, the allowance for credit loss is written off and the excess of the amortized cost basis
of the asset over its fair value is recorded in net income.
Cash and Cash Equivalents
Cash and cash equivalents
are comprised of deposits at major financial banking institutions and highly liquid investments with an original maturity of three
months or less at the date of purchase. Cash equivalents are primarily invested in money market funds. The carrying amount of our
cash equivalents approximates fair value due to the short maturity of the investments. The Company regularly monitors the financial
condition of the institutions in which it has depository accounts and believes the risk of loss is minimal.
Grants Receivable
Grants receivable result
from drawdown requests to various federal agencies for reimbursement of costs incurred during the operation of the Company’s
research and development programs.
Accounts Receivable
We report accounts
receivable at net realizable value. When required we estimate losses on uncollectible accounts receivable based upon historical
data. Such allowance for doubtful accounts is estimated based upon management’s assessment of individual accounts. The Company
concluded that an allowance for doubtful accounts is not considered necessary at June 30, 2023 and December 31, 2022, as there
was no outstanding accounts receivable.
Prepaid Expenses
Our prepaid expenses consist primarily of prepaid insurance and prepaid expenses. Our insurance products
have a 12-month term and annually renew each June, with the exception of directors’ and officers’ insurance which renews
in December. Premiums are paid in advance, either annually, semi-annually, or quarterly. The collective value of any prepaid portions
of policy terms is recorded at cost. Contracts involving pre-payment are capitalized and amortized in accordance with performance.
Long-lived Assets (equipment)
Fixed assets are recorded
at cost and depreciated over their estimated useful lives.
Laboratory and office
equipment not covered by federal grant financing is depreciated on the straight-line basis over the estimated useful lives (three to ten
years). Leasehold improvements are amortized over the shorter of the lease term or estimated useful life. Long-lived assets are
evaluated for impairment when events or changes in circumstances indicate that the carrying amount of the asset or related group
of assets may not be recoverable. If the expected future undiscounted cash flows are less than the carrying amount of the asset,
an impairment loss is recognized at that time. Measurement of impairment may be based upon appraisal, market value of similar assets
or discounted cash flows.
Equipment expenditures
that are covered by federal grant financing are depreciated using the activity method (or variable charge approach) employing an
intended purpose that expires during or by the conclusion of the funded project. Such equipment acquisition expenditures are therefore
effectively expensed if the timing of the intended purpose is within the same reporting period as delivery.
At June 30, 2023 and
December 31, 2022, the Company’s long-lived assets of $125,859 have been fully depreciated.
Accounts Payable
Accounts payable are
short term liabilities with product/service vendors, including any credit card liability.
Accrued Expenses
Accrued expenses are
recorded when incurred but have not been paid by period end. See Note 6 related to the balance at June 30, 2023 and December 31,
2022.
Revenue Recognition
On January 1, 2018,
the Company adopted ASU No. 2014-09, Revenue from Contracts with Customers (“Topic 606”), to account for revenue. The
deliverables under our arrangements are evaluated under Topic 606, which requires an entity to recognize revenue in a manner that
depicts the transfer of promised goods or services to customers in an amount that reflects the consideration to which the entity
expects to be entitled in exchange for those goods or services.
The Company recognizes
revenue when persuasive evidence of an arrangement exists, delivery occurs, the fee was fixed or determinable, and collectability
is reasonably assured.
The Company’s
contract revenue consists primarily of amounts earned under contracts with third-party customers and reimbursed expenses under
such contracts. The Company analyzes its agreements to determine whether the elements can be separated and accounted for individually
or as a single unit of accounting. Allocation of revenue to individual elements that qualify for separate accounting is based on
the separate selling prices determined for each component, and total contract consideration is then allocated pro rata across the
components of the arrangement.
In general, the Company
applies the following steps when recognizing revenue from contracts with customers: (i) identify the contract, (ii) identify the
performance obligations, (iii) determine the transaction price, (iv) allocate the transaction price to the performance obligations
and (v) recognize revenue when a performance obligation is satisfied.
Recognition of revenue
is driven by satisfaction of the performance obligations using one of two methods: revenue is either recognized over time or at
a point in time. Revenue is generally recognized as the performance obligations are satisfied, which generally occurs when control
of the goods or services have been transferred to the customer or once the customer is able to use those goods and/or services
as well as obtaining substantially all of their benefits.
The Company primarily
generates contract revenue under fixed-fee contracts or time and materials contracts:
|
● |
Under a fixed-fee contract, the Company charges a fixed agreed upon amount for a deliverable. Fixed-fee contracts have fixed deliverables upon completion of the project. Typically, the Company recognizes revenue for fixed-fee contracts after projects are completed, delivery is made and title transfers to the customer, and collection is reasonably assured. |
|
● |
Under a time and materials contract, the Company charges customers an
hourly rate plus reimbursement for other project specific costs. The Company recognizes revenue for time and material contracts
based on the number of hours devoted to the project multiplied by the customer’s billing rate plus other project specific
costs. Payment terms vary, but are generally due within 60 days. |
Grant Revenues
The Company receives
revenue through government grants, primarily with the National Institutes of Health (“NIH”). The Company has concluded
its government grants are not within the scope of Topic 606, as government entities do not meet the definition of a “customer”
as defined by Topic 606 because there is not considered to be a transfer of control of goods or services to the government entity
funding the grant. Grant revenue, which is not within the scope of Topic 606, consists of funding under cost reimbursement programs
primarily from federal and non-profit foundation sources for qualified research and development activities performed by us, and
as such, are not based on estimates that are susceptible to change. Such amounts are invoiced and recorded as revenue as grant-funded
activities are performed, with any advance funding recorded as deferred revenue until the activities are performed. The Company
believes the recognition of revenue as costs are incurred and amounts become earned/realizable is analogous to the concept of transfer
of control of a service over time under Topic 606.
Lease Obligations
The Company determines
if an agreement is a lease at inception. The Company evaluates the lease terms to determine whether the lease will be accounted
for as an operating or finance lease. Operating leases are included in operating lease right-of-use (“ROU”) assets,
operating lease liabilities, current portion, and operating lease liabilities, net of current portion in our consolidated balance
sheets.
ROU assets represent
our right to use an underlying asset for the lease term, and lease liabilities represent our obligation to make lease payments
arising from the lease. Operating lease ROU assets and liabilities are recognized at commencement date based on the present value
of lease payments over the lease term. As most of our leases do not provide an implicit rate, we use our incremental borrowing
rate based on the information available at commencement date in determining the present value of lease payments. The Company uses
the implicit rate when readily determinable. The operating lease ROU asset also includes any lease payments made and excludes lease
incentives. Our lease terms may include options to extend or terminate the lease when it is reasonably certain that we will exercise
that option. Lease expense for lease payments is recognized on a straight-line basis over the lease term.
A lease that transfers
substantially all of the benefits and risks incidental to ownership of property are accounted for as finance leases. At the inception
of a finance lease, an asset and finance lease obligation is recorded at an amount equal to the lesser of the present value of
the minimum lease payments and the property’s fair market value. Finance lease obligations are classified as either current
or long-term based on the due dates of future minimum lease payments, net of interest. At June 30, 2023 and December 31, 2022,
there were no finance leases.
Research and Development
The Company accounts
for research and development costs in accordance with ASC 730-10, Research and Development (“ASC 730-10”).
Under ASC 730-10, all research and development costs must be charged to expense as incurred. Accordingly, internal research and
development costs are expensed as incurred. Third-party research and development costs are expensed when the contracted work has
been performed or as milestone results have been achieved. Research and development expenses include salaries and benefits, facilities
and other overhead expense, external clinical trial expenses, research related manufacturing services, contract services and other
outside expenses.
Patent Costs and Rights
Costs of applying for,
prosecuting and maintaining patents and patent rights are expensed as incurred due to uncertainty of future economic benefit.
Clinical Trial Costs
Clinical trial costs
are charged to us and recognized as the tasks are completed by the contractor(s) or, alternatively, may be invoiced in accordance
with agreed-upon payment schedules and recognized based on estimates of work completed to date.
Stock Option Compensation Expense
The Company recognizes the fair value of stock option award expenses on a straight-line basis over a service
period of three years, consistent with vesting periods, using the Black-Scholes options pricing model to estimate the fair value
of option awards. Such expenses are categorized as research and development or general and administrative depending on the role
of each option recipient.
The Company recognizes
the income tax benefits and deficiencies as income tax expense or benefit in the statement of operations and the tax effects of
exercised or vested awards are treated as discrete items in the reporting period in which they occur. The Company also recognizes
excess tax benefits regardless of whether the benefit reduces taxes payable in the current period. Excess tax benefits are classified
along with other income tax cash flows as an operating activity in the statement of cash flows. Regarding forfeitures, the Company
accounts for them when they occur. See Note 9 for more information on our stock options.
Warrants
The Company accounts
for Common Stock warrants as either liabilities or as equity instruments depending on the specific terms of the warrant agreements.
Generally, warrants are classified as liabilities, as opposed to equity, if the agreement includes the potential for a cash settlement
or an adjustment to the exercise price, and warrant liabilities are recorded at their fair values at each balance sheet date. See
Note 12 related to issued warrants.
Income Taxes
The Company accounts
for income taxes in accordance with the asset and liability method of accounting for income taxes prescribed by FASB ASC Topic
740, “Accounting for Income Taxes” (“ASC 740”). Under the asset and liability method of ASC 740,
deferred tax assets and liabilities are recognized for the future tax consequences attributable to differences between the financial
statement carrying amounts of existing assets and liabilities and their respective tax basis and operating loss and tax credit
carry-forwards. Deferred tax assets and liabilities are measured using enacted tax rates expected to apply to the taxable income
in the years in which those temporary differences are expected to be recovered or settled. Under ASC 740, the effect on deferred
tax assets and liabilities of a change in tax rates is recognized in income in the period that includes the enactment dates. The
Company evaluates its deferred income taxes to determine if a valuation allowance should be established against the deferred tax
assets or if the valuation allowance should be reduced based on consideration of all available evidence, both positive and negative,
using a “more likely than not” standard.
The Company follows
FASB ASC Topic 740-10, “Accounting for Uncertainty in Income Taxes” (“Topic 740-10”), which prescribes
a recognition threshold and measurement attribute for financial statement recognition and measurement of a tax position taken,
or expected to be taken, in a tax return. For those benefits to be recognized, a tax position must be more likely than not to be
sustained upon examination by taxing authorities. At June 30, 2023 and December 31, 2022, the Company had no material uncertain
tax positions to be accounted for in the financial statements. The Company recognizes interest and penalties, if any, related to
unrecognized tax benefits in interest expense. See Note 14 related to income taxes.
Concentration of Credit Risk
The
Company’s grant revenues and grant receivables were with the NIH. The NIH is an agency of the United States Department of
Health & Human Services, and the Company believes amounts are fully collectible from this agency. Contract revenues were $224,724
for the six months ended June 30, 2023, and $106,676 for the three months ended June 30, 2023.
Earnings Per Share
Basic
net loss per share of Common Stock is computed by dividing the net loss for the period by the weighted-average number of
shares of Common Stock outstanding during the period. Diluted net loss per common share is computed giving effect to all dilutive
Common Stock equivalents, consisting of stock options and warrants. Diluted net loss per share of Common Stock for the six months
ended June 30, 2023 and 2022 is the same as basic net loss per share, as the Common Stock equivalents were anti-dilutive due to
the net loss.
Due to the Stock Split, the shares outstanding
at June 30, 2022 have been retroactively adjusted, reducing them from 9,666,562 to 3,866,625. This had a corresponding increase
in the loss per share of Common Stock from $0.16 to $0.39 per share for the six months ended June 30, 2022, and from $0.08 to $0.20
per share for the three months ended June 30, 2022.
At June 30, 2023 and 2022, the Common Stock equivalent shares
were, as follows:
Schedule of common stock equivalent shares
| |
|
|
|
|
|
| |
| |
June
30, | |
| |
2023 | | |
2022 | |
Shares
of Common Stock issuable under equity incentive plans outstanding | |
| 2,478,000 | | |
| 2,054,000 | |
Shares of Common Stock
issuable upon exercise of warrants
| |
| 143,994 | | |
| 143,994 | |
Shares
of Common Stock issuable upon conversion of Series A Preferred Stock | |
| — | | |
| 636,979 | |
Common
Stock equivalent shares excluded from diluted net loss per share | |
| 2,621,994 | | |
| 2,834,973 | |
Note 4. Fair Value Measurements and Marketable Debt Securities
In accordance with
ASC 820, “Fair Value Measurements and Disclosures” (“ASC 820”), the Company measure its assets and
liabilities at fair value. We apply the three-level valuation hierarchy as described in ASC 820, which is based upon the transparency
of input as of the measurement date. The three levels of inputs as defined are:
Level 1 - Inputs to the
valuation methodology are quoted prices (unadjusted) for identical assets or liabilities in active markets.
Level 2 - Inputs to the
valuation methodology include quoted prices for similar assets and liabilities in active markets, and inputs that are observable
for the asset or liability, either directly or indirectly, for substantially the full term of the financial instruments.
Level 3 - Inputs to the
valuation methodology are unobservable and significant to the fair value measurement.
At June 30, 2023 and
December 31, 2022, the Company’s financial instruments consist primarily of: cash and cash equivalents, accounts payable
and accrued liabilities. For cash equivalents, accounts payable and accrued liabilities, the carrying amounts of these financial
instruments as of June 30, 2023 and December 31, 2022 were considered representative of their fair values due to their short term
to maturity.
The Company held no
marketable securities or cash equivalents at December 31, 2022, and no marketable securities at June 30, 2023. For cash equivalents
at June 30, 2023 the fair value input levels are summarized below:
June 30, 2023 | |
Level 1 | | |
Level 2 | | |
Level 3 | | |
Total | |
Cash Equivalents (maturity less than 90 days) | |
| | | |
| | | |
| | | |
| | |
Commercial Paper | |
$ | — | | |
| — | | |
| — | | |
$ | — | |
U.S. Government | |
| — | | |
| — | | |
| — | | |
| — | |
Money market funds | |
| 2,801,063 | | |
| — | | |
| — | | |
| 2,801,063 | |
Total Cash equivalents | |
| 2,801,063 | | |
| | | |
| | | |
| 2,801,063 | |
| |
| | | |
| | | |
| | | |
| | |
Marketable Securities | |
| — | | |
| — | | |
| — | | |
| — | |
Total Cash Equivalents and Marketable Securities | |
$ | 2,801,063 | | |
$ | — | | |
$ | — | | |
$ | 2,801,063 | |
Note 5. Prepaid Expenses
At June 30, 2023, prepaid
expenses consisted primarily of prepaid insurance of $194,384 and $30,918 in prepaid expenses. At December 31, 2022, prepaid expenses
consisted of $433,891 of prepaid insurance, and $130,000 of prepaid investor relations and advisory services.
Note 6. Accrued Expenses
At June 30, 2023 accrued
expenses were $138,704, resulting from unbilled clinical expenses of $28,675 and $110,029 of unbilled professional services expenses.
At December 31, 2022, the $389,209 of accrued expenses consisted of $224,871 in accrued professional expenses, and $164,338 in
accrued clinical expenses.
Note 7. Notes Payable – Related Party
At December 31, 2022,
there was a $250,000 note outstanding, payable to Dr. Jonathan Kaufman, the Company’s Chief Executive Officer. The note payable
was due within one year and was issued by the Company in exchange for cash contributions made by Dr. Kaufman to the Company. The
note and accrued interest were paid in full as of June 30, 2023.
The note obligation and accrued interest are provided in the following table.
Origination | | |
Original Principal | | |
Current Principal | | |
Rate | | |
Maturity | | |
Accrued Interest - Related Party December 31, 2022 | | |
Accrued Interest - Related Party March 31, 2023 | | |
Accrued Interest - Related Party June 30, 2023 | | |
Category | |
November 1, 2022 | | |
$ | 250,000 | | |
$ | - | | |
| 8.75 | % | |
| 06/30/23 | | |
$ | 3,596 | | |
$ | 8,990 | | |
$ | — | | |
| Current | |
Note 8. Letter of Credit
The Company has a letter
of credit with a bank for an aggregate available borrowing of $50,000 due upon demand. The letter of credit is collateralized by
substantially all of the Company’s assets and personally guaranteed by Dr. Jonathan Kaufman, the Company’s Chief Executive
Officer. The outstanding advances under the line of credit bear interest at the lending bank’s prime rate plus 3.10%. In
February 2023, the Company repaid all amounts outstanding under the letter of credit. The outstanding balance was $0 and $25,000
at June 30, 2023 and December 31, 2022, respectively.
Note 9. Stock Options
The
Company previously had two incentive plans in effect pursuant to which incentive stock options and nonqualified stock options
were issued. The maximum number of shares Common Stock that may be issued upon exercise of such outstanding options as of June
30, 2023 was 2,478,000 shares. This number comprises 1,078,000 unexpired options issued and outstanding granted under the
Company’s expired 2008 Stock Incentive Plan and 1,400,000 options issued and outstanding granted under the Company’s
Amended and Restated Stock Incentive Plan, which was originally adopted in 2020 and amended and restated in 2022 (the “2020
Plan”), which is the only Company incentive plan currently in effect. Incentive stock options granted under the 2020 Plan
are granted with an exercise price determined by the Company’s board of directors (the “Board”) or the Board’s compensation committee (the “Compensation Committee”).
Unless otherwise provided for by the Board or the Compensation Committee, vesting of options granted under the 2020 Plan terminates once the
optionee is no longer affiliated with the Company, subject to certain exceptions. Such options generally expire ten years from
the date of the grant (five years in the case of incentive stock options granted to holders of over 10% of Common Stock). Stock
options are granted under the 2020 Plan with an exercise price not less than the fair market value of the underlying Common Stock
on the date of the grant and incentive stock options granted to holders of over 10% of Common Stock are granted with an exercise
price not less than 110% of such fair market value on such grant date. Unless otherwise specified by the Board or the Compensation Committee,
all grants under the 2020 Plan vest fully over a three-year period, provided that the employee continues to be employed, subject
to certain exceptions. If an employee leaves the Company prior to the full vesting of such option awards, then the remaining unvested
portion is considered forfeited, and the earlier recognition of the unvested shares is reversed during the period of forfeiture.
As of June 30, 2023 and December 31, 2022 there was $806,157 and $1,222,500, respectively, of unrecognized compensation costs
related to non-vested share-based compensation arrangements granted to be recognized over the weighted average period of approximately
18 months.
The Company recognized
$847,618 and $213,489 of compensation costs related to stock option vesting for the three months ended June 30, 2023 and 2022,
respectively. The Company recognized $1,056,257 and $448,637 of compensation costs related to stock option vesting for the six
months ended June 30, 2023 and 2022, respectively.
The following is an analysis of options to purchase shares of Common Stock issued and outstanding as of
June 30, 2023 and December 31, 2022:
| |
Shares | | |
Weighted- Average Exercise Price Per Share ($) | | |
Weighted- Average Remaining Contractual Term (in Years) | | |
Aggregate intrinsic value ($) | |
Outstanding as of December 31, 2021 | |
| 2,044,000 | | |
| 2.82 | | |
| 6.61 | | |
| 4,446,667 | |
Granted | |
| 10,0000 | | |
| 5.00 | | |
| 9.16 | | |
| | |
Expired | |
| — | | |
| | | |
| | | |
| | |
Cancelled | |
| — | | |
| | | |
| | | |
| | |
Exercised | |
| — | | |
| | | |
| | | |
| | |
Outstanding as of December 31, 2022 | |
| 2,054,000 | | |
| 2.84 | | |
| 5.51 | | |
| 605,687 | |
Granted | |
| — | | |
| | | |
| | | |
| | |
Expired | |
| — | | |
| | | |
| | | |
| | |
Cancelled | |
| — | | |
| | | |
| | | |
| | |
Exercised | |
| — | | |
| | | |
| | | |
| | |
Outstanding as of March 31, 2023 | |
| 2,054,000 | | |
| 2.84 | | |
| 5.26 | | |
$ | — | |
Granted | |
| 424,000 | | |
| 2.19 | | |
| 9.96 | | |
| | |
Expired | |
| — | | |
| | | |
| | | |
| | |
Cancelled | |
| — | | |
| | | |
| | | |
| | |
Exercised | |
| — | | |
| | | |
| | | |
| | |
Outstanding as of June 30, 2023 | |
| 2,478,000 | | |
| 2.72 | | |
| 5.86 | | |
$ | — | |
Vested as of June 30, 2023 | |
| 2,190,667 | | |
| | | |
| | | |
| | |
Exercisable as of June 30, 2023 | |
| 2,190,667 | | |
| | | |
| | | |
| | |
Exercisable as of December 31, 2022 | |
| 1,619,333 | | |
| | | |
| | | |
| | |
A
summary of status of the Company’s non-vested stock options (exercisable for shares of Common Stock on a one-to-one basis)
as of, and changes during, the six months ended June 30, 2023 and 2022 is presented below:
| |
Number of Stock Options | | |
Weighted- Average Fair Value Grant Date | |
Nonvested at December 31, 2021 | |
| 688,667 | | |
$ | 2.82 | |
Granted | |
| 10,000 | | |
$ | 2.84 | |
Vested | |
| (157,333 | ) | |
$ | 2.83 | |
Expired | |
| — | | |
$ | 0.00 | |
Nonvested at June 30, 2022 | |
| 541,333 | | |
$ | 2.82 | |
| |
| | | |
| | |
Nonvested at December 31, 2022 | |
| 434,667 | | |
$ | 2.82 | |
Granted | |
| 424,000 | | |
| 2.19 | |
Vested | |
| (423,334 | ) | |
| 2.83 | |
Expired | |
| — | | |
| — | |
Nonvested at June 30, 2023 | |
| 435,333 | | |
$ | 2.81 | |
In
the six months ended June 30, 2023 and 2022, the Company granted options as presented below.
Stock
Option Grants - On March 1, 2022, the Company issued 10,000 stock options at a $5.00 strike price, vesting immediately upon
issuance.
On
June 16, 2023, the Company issued 424,000 stock options at a $2.19 strike price, vesting immediately upon issuance.
The
weighted-average fair value of stock options on the date of grant and the assumptions used to estimate the fair value of stock
options granted during the six months ended June 30, 2023 and June 30, 2022 using the Black-Scholes option-pricing model is as
follows:
Six months ended June 30: | |
2023 | | |
2022 | |
Weighted-average fair value of options granted | |
$ | 1.50 | | |
| 1.14 | |
Expected volatility | |
| 83.47 | % | |
| 75 | % |
Expected life (in years) | |
| 5.04 | | |
| 10 | |
Risk-free interest rate (range) | |
| 3.99 | % | |
| 2.31 | % |
Expected dividend yield | |
$ | — | | |
| — | |
Note
10. Preferred Stock
The
Company’s Second Amended and Restated Certificate of Incorporation (the “Charter”) authorizes the issuance
of 20,000,000 shares of preferred stock, par value $0.0001 per share. The Company’s Certificate of Designation of Preferences,
Rights and Limitations of Series A Preferred Stock sets forth the rights of the Series
A Preferred Stock, par value $0.0001 per share, of the Company (the “Series A Stock”) and authorizes the issuance
of up to 5,000,000 shares of Series A Stock. With respect to dividend rights and rights in the event of the liquidation or dissolution
of the Company, the Series A Stock ranks prior to all Common Stock and any other series of preferred stock which is junior to
Series A Stock. Upon any matter submitted to the shareholders of the Company for a vote, each holder of Series A Stock is entitled
to the number of votes as is equal to the number of shares of Common Stock into which such shares of Series A Stock are convertible
at the time of such vote. The Series A Stock is not entitled to any mandatory dividends.
The
Series A Stock is convertible into Common Stock on a one-to-one basis. In the event of the liquidation or dissolution of the Company,
the holders of the Series A Stock are entitled to receive the greater of $0.60 per share, representing a liquidation preference
of $0 as of June 30, 2023 and December 31, 2022. The Series A Stock is not entitled to dividends, and is not considered “participating”
preferred, meaning converted securities are not entitled to a liquidation preference, and if a liquidation preference has been
taken, the associated security interest is dissolved. Prior to the completion of our initial public offering, all of the Series
A Stock would have automatically converted into Common Stock upon any one of the following three conditions: a public offering
of at least $7,000,000 of gross proceeds, the optional conversion of at least 80% of issued shares of Series A Stock, or the consent
of holders of a majority of the Series A Stock. The shares of Series A Stock have average-weighted anti-dilution protection that
becomes effective upon the issuance of Common Stock (or securities convertible into Common Stock) at a price below $0.60 per share.
If
upon a liquidation event the assets of the Company available for distribution are insufficient to pay the holders of the Series
A Stock the full amount as to which they are entitled, then the entire amount available will be distributed among the holders
of the Series A Stock ratably in accordance with the respective amounts that would have been payable on such shares of Series
A Stock if the amounts were paid in full. If after the Series A Stock holders have been paid in full, the Common Stock shall be
entitled to receive any and all assets remaining to be paid or distributed.
In
the year ended December 31, 2022, all 1,592,447 outstanding shares of Series A Stock were converted to Common Stock on a 1:1 basis.
After the effect of the Stock Split, this conversion resulted in 636,979 shares of Common Stock. There were no shares of Series
A Stock outstanding at December 31, 2022 or June 30, 2023.
Note
11. Common Stock
The
Charter authorizes the issuance of 200,000,000 shares of Common Stock. On December 19, 2022, the Company effected the Stock Split,
with a 2.5 to 1 share conversion ratio for all shares of Common Stock outstanding. The Company’s outstanding share and per
share amounts in these unaudited condensed financial statements have been adjusted to give effect to the Stock Split, for all periods presented. There
were 5,743,945 shares of Common Stock outstanding as of June 30, 2023 and December 31, 2022.
During
the year ended December 31, 2022, the Company issued 22,950 shares of Common Stock in forgiveness of two related party notes.
The aggregate principal and interest of the notes was $138,810. On December 22, 2022, we completed an initial public offering
(“IPO”) and listing on the Nasdaq Capital Market (“Nasdaq”) of our Common Stock at a price to the public
of $5.75 per share, which resulted in the issuance of an additional 1,217,391 shares of Common Stock. The aggregate net proceeds
from the IPO were approximately $5,000,000 after deducting underwriting discounts and commissions of $630,000 and offering expenses
of approximately $1,160,000.
The
Common Stock is subject to and qualified by the rights of the Series A Stock. Upon the dissolution or liquidation of the Company
the holders of Common Stock will be entitled to receive all assets of the Company available for distribution to its stockholders,
subject to any preferential rights of any then outstanding Series A Stock.
Note
12. Warrants
No
warrants were issued in the six months ended June 30, 2023, or the year ended December 31, 2022. In the year ended December 31,
2021, in connection with the issuance of shares of Common Stock, 143,994 warrants exercisable into an equal number of shares of
Common Stock were issued. The warrants have a 5-year term and an exercise price of $5.00 per share (after giving effect to the
Stock Split). The Company had no warrant liabilities at June 30, 2023 or December 31, 2022.
Note
13. Commitment and Contingencies
Operating
Leases
Operating
leases are recorded as ROU assets and lease liabilities on the balance sheet. ROU assets represent our right to use the leased
asset for the lease term and lease liabilities represent our obligation to make lease payments. Operating lease ROU assets and
liabilities are recognized at commencement date based on the present value of lease payments over the lease term. As most of the
Company’s leases do not provide an implicit rate, the Company uses its estimated incremental borrowing rate at the commencement
date to determine the present value of lease payments. The operating lease ROU assets also include any lease payments made and
exclude lease incentives.
The
Company entered into a lease agreement beginning July 1, 2020, for the Company’s principal headquarters at 7800 Susquehanna
Street, Pittsburgh, Pennsylvania, which includes office space and sterile manufacturing operations (the “Lease”).
The Lease has a five-year term and includes an option for renewal, which is not reasonably certain and is excluded from the right
of use calculation. Future minimum rent payments under the Lease as of June 30, 2023 are as follows:
Year ending | |
| |
2023 (6 months remaining) | |
$ | 33,476 | |
2024 | |
$ | 67,289 | |
2025 | |
$ | 33,813 | |
Total minimum lease payments | |
$ | 134,578 | |
Less: amount representing interest | |
$ | (8,400 | ) |
Present value of minimum lease payments | |
$ | 126,178 | |
The
Lease is accounted for as a ROU and liability. As of June 30, 2023, the Company has $122,547 of an operating lease ROU asset,
and $60,788 and $65,390 of current and non-current lease liabilities, respectively, recorded on the balance sheets. As of December
31, 2022 the Company had an ROU asset of $150,821, and current and non-current operating lease liabilities of $58,262 and $96,258
respectively. The lease expense for the three months ended June 30, 2023 and June 30, 2022 was $16,436 and $16,245, respectively.
The lease expense for the six months ended June 30, 2023 and June 30, 2022 was $32,737 and $32,602, respectively. Cash paid for
the amounts included in the measurement of lease liabilities for the three months ended June 30, 2023 and June 30, 2022 was $16,402
and $16,066, respectively, and for the six months ended June 30, 2023 and 2022 was $32,804 and $32,131 respectively. The payments
are included in the operating activities in the accompanying statement of cash flows.
Contract
Commitments
The
Company enters into contracts in the normal course of business with contract research organizations (“CROs”), contract
manufacturing organizations (“CMOs”), universities, and other third parties for preclinical research studies, clinical
trials and testing and manufacturing services. These contracts generally do not contain minimum purchase commitments and are cancelable
by us upon prior written notice although, purchase orders for clinical materials are generally non-cancelable. Payments due upon
cancellation consist only of payments for services provided or expenses incurred, including non-cancelable obligations of our
service providers, up to the date of cancellation or upon the completion of a manufacturing run.
Partnering
Commitments
In
February 2022, the Company entered into an agreement whereby it partnered with an advisor to assist with potential transactions.
The Company paid $10,000 per month for the first four months of the agreement’s term. The agreement (which was terminated
in June 2022), included a surviving success fee, such that in the event of a successful transaction occurring prior to September
2023, required the Company to make a payment equal to the greater of (a) five percent of the transaction value and (b) $500,000.
For the three months ended June 30, 2023, and June 30, 2022, the Company has recorded $0 and $30,000, respectively, in general
and administrative expense related to this commitment, and has not recorded any additional liabilities related to the surviving
success fee clause as of the balance sheet date.
Note
14. Income Taxes
The
provision for income taxes for the three and six months ended June 30, 2023 and 2022 was $0, resulting in an effective income
tax rate of 0% for each period. The Company’s effective tax rate for the three and six months ended June 30, 2023 and 2022
is primarily due to the full valuation allowance against the Company’s net deferred tax assets.
The
Company regularly evaluates the realizability of its deferred tax assets and establishes a valuation allowance if it is more likely
than not that some or all of the deferred tax assets will not be utilized. Because of our cumulative losses, substantially all
of the deferred tax assets have been fully offset by a valuation allowance as of June 30, 2023 and December 31, 2022. We have
not paid income taxes for the year ended December 31, 2022.
The
Company’s 2018 through 2022 tax years remain subject to examination by the Internal Revenue Service for federal tax purposes
and the State of Pennsylvania for state tax purposes.
Note
15. Subsequent Events
Subsequent
events have been evaluated through the date of the independent auditors’ report , which is the date the unaudited condensed financial statements
were available to be issued.
Effective August 1, 2023, the Company became party to a lease for additional space at their current
location (the “August 2023 Lease”). The August 2023 Lease will co-terminate with the Lease on June 30, 2025, with an option to extend for five years. Under
the August 2023 Lease, the Company expects to pay an additional $11,483 in rent during the calendar year 2023.
Item
2. Management’s Discussion and Analysis of Financial Condition and Results of Operations.
The
following discussion and analysis of our financial condition and results of operations for the three and six months ended June
30, 2023 should be read together with our unaudited condensed financial statements and related notes included in Item 1 of Part I of this Quarterly
Report on Form 10-Q for the quarterly period ended June 30, 2023 (this “Form 10-Q”), as well as the audited financial
statements, the related notes thereto and management’s discussion and analysis of financial condition and results of operations
for the year ended December 31, 2022 contained in our Annual Report on Form 10-K for the year ended December 31, 2022, that was
filed with the SEC on March 31, 2023 (our “Annual Report”), and all risk factors disclosed herein and therein. Such
discussion contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended (the
“Securities Act”), and Section 21E of the Securities Exchange Act of 1934, as amended (the “Exchange Act”),
as well as information relating to our business that reflect our management’s current views, expectations and assumptions
concerning our business, strategies, products, future results and events and financial performance, which are subject to risks
and uncertainties that may cause our, or our industry’s, actual results, levels of activity, performance or achievements
to be materially different from any future results, levels of activity, performance or achievements expressed or implied by such
forward-looking statements. Such forward-looking statements speak only as of the date of this Form 10-Q. Although we believe that
the expectations reflected in such forward-looking statements are reasonable, we cannot guarantee future results, levels of activity
or achievements or that our underlying assumptions will prove to be correct. Except as required by applicable law, including the
securities laws of the United States, we expressly disclaim any obligation or undertaking to disseminate any update or revisions
to any such forward-looking statement to reflect any change in our expectations with regard thereto or to conform such forward-looking
statements to actual results. Statements made in this Form 10-Q, other than statements of historical fact, addressing operating
performance, events, or developments which our management expects or anticipates will or may occur in the future, and also statements
related to expected or anticipated growth, revenues, profitability, new products, adequacy of funds from operations, statements
expressing general optimism about future operating results, and other non-historical information, are forward-looking statements.
In particular, the words “may,” “will,” “expects,” “anticipates,” “aims,”
“potential,” “future,” “intends,” “plans,” believes,” “estimates,”
“continue,” “likely to,” and variations of such words and similar expressions identify forward-looking
statements, but such words are not the exclusive means of identifying such forward-looking statements, and their absence does
not necessarily mean that such statement is not forward-looking.
Overview
We
are a clinical-stage biotechnology company focused on developing new drugs by reformulating the active agents in existing generic
drugs and optimizing these reformulations for new applications. We believe that this strategy combines many of the cost efficiencies
and risk abatements derived from using existing generic drugs with potential patent protections for our proprietary formulations;
this strategy allows us to expedite, protect, and monetize our product candidates. Additionally, we maintain a therapeutic focus
on diseases with significant, unaddressed morbidity and mortality where no approved drug therapy currently exists. We believe
that this focus can potentially help reduce the cost, time and risk associated with obtaining marketing approval.
Consistent
with our strategy, the initial indication that we are currently addressing (via development of our product candidate, which we
have designated as LP-10) is hemorrhagic cystitis (“HC”), which is chronic, uncontrolled urinary blood loss that results
from certain chemotherapies (such as alkylating agents) or pelvic radiation therapy (also called “radiation cystitis”).
Many radiation cystitis patients experience severe morbidity (and in some cases, mortality), and currently, there is no therapy
for their condition approved by the U.S. Food and Drug Administration (“FDA”), or, to our knowledge, any other regulatory
body. LP-10 is the development name of our reformulation of tacrolimus (an approved generic active agent) specifically optimized
for topical deposition to the internal surface of the urinary bladder lumen using a proprietary drug delivery platform that we
have developed and that we refer to as our metastable liposome drug delivery platform (our “Platform”). We are developing
LP-10 and our Platform to be, to our knowledge, the first drug candidate and drug delivery technology that could be successful
in treating cancer survivors who acquire HC.
In
a second program, we are developing a product candidate, which we have designated LP-310 and which employs a formulation similar
to LP-10, for the treatment of oral lichen planus (“OLP”). OLP is a chronic, T-cell-mediated, autoimmune oral mucosal
disease, and LP-310 contains tacrolimus which inhibits T-lymphocyte activation. Symptoms of OLP include painful burning sensations,
bleeding and irritation with tooth brushing, painful, thickened patches on the tongue, and discomfort when speaking, chewing or
swallowing. These symptoms frequently cause weight loss, nutritional deficiency, anxiety, depression, and scarring from erosive
lesions. OLP can also be a precursor to cancer, predominately squamous cell carcinoma, with a malignant transformation rate of
approximately one percent. LP-310 is the development name of our oral, liposomal formulation of tacrolimus (the same approved
generic active agent in LP-10) specifically optimized for local delivery to oral mucosa. We believe that our approach of using
metastable liposomal tacrolimus as a treatment for OLP is novel. To date, upon review of relevant FDA public data resources on
approved drugs and biologics, we are not aware of any other liposomal products developed to treat such disease. We have completed
a pre-investigational new drug meeting with the FDA and intend to submit the full investigational new drug application to the
FDA for LP-310 in the third quarter of 2023.
Our
Platform includes proprietary drug delivery technologies optimized for use with epithelial tissues that coat lumenal surfaces,
such as the colon, the various tissues lining the mouth and esophagus and the tissues lining the bladder and urethra. The Company
has two issued patents in the United States that should exclude competitors from making, selling or using our LP-10 and LP-310
formulations in the United States until July 11, 2035. We also have issued patents in Australia, Canada, and Europe that do not
expire until October 22, 2034. Corresponding patent applications are pending in the United States Patent Offices. We also have
a pending United States patent application on an improvement to the technology.
Since
our inception in 2005, we have focused primarily on business planning and progressing our lead product candidates, including progressing
LP-10 through clinical development, raising capital, organizing and staffing the Company. On December 22, 2022, we completed our
initial public offering (the “IPO”) and issued an aggregate of 1,217,391 shares of Common Stock at a price of $5.75
per share. The aggregate net proceeds from the IPO were approximately $5.0 million after deducting underwriting discounts and
commissions of approximately $630,000 and offering expenses of approximately $1.16 million.
Recent
Developments
Effective August 1, 2023, we entered into
the August Lease for additional space adjacent to the Company’s current principal executive office space. The August 2023
Lease commenced on August 1, 2023 and will co-terminate with the Company’s existing lease for its principal executive offices
on June 30, 2025. The August 2023 Lease and the Company’s current lease each have an option for a five-year extension. The
incremental rent expense from the August 2023 Lease is expected to be approximately $11,500 through December 31, 2023.
On August 4, 2023, the Company entered
into an agreement amending the Company’s existing employment agreement with Dr. Jonathan Kaufman, Chief Executive Officer
of the Company, to increase Dr. Kaufman’s annual base salary by $50,000, to $233,300. Also on August 4, 2023, the Company
entered into an agreement amending the Company’s existing employment agreement with Dr. Michael Chancellor, Chief Medical
Officer of the Company, to increase Dr. Chancellor’s annual base salary by $50,000,
to $225,000.
Results
of Operations
Comparison
of the Three Months Ended June 30, 2023 and 2022
The
following table summarizes our results of operations for the three months ended June 30, 2023 and 2022 (in thousands):
| |
Three Months Ended | | |
| |
| |
June 30, | | |
Increase | |
| |
2023 | | |
2022 | | |
(Decrease) | |
(in thousands) | |
| | |
| | |
| |
Revenue | |
$ | 107 | | |
| — | | |
$ | 107 | |
Operating expenses: | |
| | | |
| | | |
| | |
Research and development (“R&D”) | |
| 1,058 | | |
| 743 | | |
| 315 | |
General and administrative | |
| 624 | | |
| 38 | | |
| 586 | |
Total operating expenses | |
| 1,682 | | |
| 781 | | |
| 901 | |
Loss from operations | |
| (1,575 | ) | |
| (781 | ) | |
| (794 | ) |
Other income (expense) | |
| 36 | | |
| (1 | ) | |
| 37 | |
Net loss | |
$ | (1,539 | ) | |
$ | (782 | ) | |
$ | (757 | ) |
Grants
and Other Revenue
We
have not yet commercialized any products and we do not expect to generate revenue from sales of any product candidates for several
years. For the three months ended June 30, 2023, we recognized revenue from a grant awarded by the NIH in September of 2022 (the
“2022 NIH Grant”), which was an award of an aggregate of $673,000. NIH approved an additional year of funding under
the 2022 NIH Grant in June 2023, increasing the total funding provided under the 2022 NIH Grant to $1,353,000.
We
recognize revenue from grants when the related costs are incurred and the right to payment is realized. For the three months ended
June 30, 2023, we earned $107,000 in connection with the 2022 NIH Grant, recognized as revenue, compared with no revenue in the
three months ended June 30, 2022. We expect to receive approximately $500,000 from the 2022 NIH Grant in total in
the calendar year 2023. The increase in annual grant revenue from 2022 to 2023 is related to the award of the 2022
NIH Grant.
Operating
Expenses
Our
operating expenses consist of (i) R&D expenses and (ii) general and administrative expenses.
Research
and Development Expenses
R&D
costs primarily consist of direct costs associated with consultants and materials, biologic storage, third party CRO costs and
contract development and manufacturing expenses, salaries and other personnel-related expenses. R&D costs are expensed as
incurred. More specifically, these costs include:
|
● |
costs of funding
research performed by third parties that conduct research and development and nonclinical and clinical activities on our behalf; |
|
● |
costs of manufacturing
drug supply and drug product; |
|
● |
costs of conducting
nonclinical studies and clinical trials of our product candidates; |
|
● |
consulting and professional
fees related to research and development activities, including equity-based compensation to non-employees; |
|
● |
costs related to
compliance with clinical regulatory requirements; and |
|
● |
employee-related
expenses, including salaries, benefits and stock-based compensation expense for our research and development personnel. |
Costs
for certain activities are recognized based on an evaluation of the progress to completion of specific tasks using data, such
as information provided to us by our vendors, and analyzing the progress of our nonclinical and clinical studies or other services
performed. Significant judgment and estimates are made in determining the accrued expense balances at the end of any reporting
period. Advance payments that we make for goods or services to be received in the future for use in R&D activities are recorded
as prepaid expenses. Such amounts are recognized as an expense as the goods are delivered or the related services are performed,
or until it is no longer expected that the goods will be delivered or the services rendered.
We
expect that our R&D expenses will increase substantially in connection with our clinical development activities for our LP-10
program. At this time, we cannot accurately estimate or know the nature, timing and costs of the efforts that will be necessary
to complete the clinical development of, or obtain regulatory approval for, any of our current or future product candidates. This
is due to the numerous risks and uncertainties associated with product development and commercialization, including the specific
factors set forth in the section of our Annual Report titled “Risk Factors.” If any events described in the applicable
risk factors included in the section of our Annual Report titled “Risk Factors” occur, then the costs and timing associated
with the development of any of our product candidates could significantly change. We may never succeed in obtaining regulatory
approval for, of commercialization of, LP-10 or any of our other product candidates.
R&D
expenses increased by approximately $315,000, from $743,000 for the three months ended June 30, 2022 to $1,058,000 for the
three months ended June 30, 2023. The increase in R&D expenses was primarily attributable to increases in stock option
expense of $314,000, personnel costs of $10,000, and overhead and facility related costs, including supplies, of $54,000.
These were offset by a reduction in outside services expense by $68,000 compared to the same period in the prior
year.
General
and Administrative Expenses
General
and administrative expenses consist primarily of management and business consultants and other related costs, including stock-based
compensation. General and administrative expenses also include board of directors’ expenses and professional fees for legal,
patent, consulting, accounting, auditing, tax services and insurance costs.
General
and administrative expenses were $624,000 for the three months ended June 30, 2023, compared to $39,000 for the three months ended
June 30, 2022. General and administrative expenses increased by approximately $586,000, including an increase in outside services
costs of $101,000, an increase in franchise tax, licensing, and filing fees of $12,000, and an increase in insurance expense of
$101,000. Additionally, stock option expense increased $320,000, related to our June 2023 option grants, and other personnel costs
(including payroll taxes and benefits) increased by approximately $42,000. The increase in G&A expenses was associated with
the Company becoming a public reporting company, including the costs of additional personnel, accounting, audit, legal,
regulatory and tax-related services associated with maintaining compliance with exchange listing and SEC requirements, director
and officer insurance costs, and investor and public relations costs.
Net
Other Income (Expense)
Net other income for the three months ended
June 30, 2023 was $36,000, as compared to a loss of $1,000 for the three months ended June 30, 2022. This balance primarily included
(i) cash interest income, (ii) unrealized loss on investments and (iii) non-cash interest expense on related party notes. A higher
cash investment balance and more favorable rates resulted in an increase of $41,000 in interest receivable on short term investments
in the three months ended June 30, 2023, compared to the same period in the prior year. Meanwhile, interest expense on related
party notes increased by $4,000 due to an increase in the principal of the notes outstanding from $75,000 during the three months
ended June 30, 2022 to $250,000 during the three months ended June 30, 2023. The related party notes were paid in full as of June
30, 2023. See Note 7 of the notes to our unaudited condensed financial statements included in this Form 10-Q as well as Note 7
of the notes to our financial statements in our Annual Report for details of such related party notes and accrued interest at the
respective periods.
Comparison
of the Six Months Ended June 30, 2023 and 2022
The
following table summarizes our results of operations for the six months ended June 30, 2023 and 2022 (in thousands):
|
|
Six
Months Ended |
|
|
|
|
|
|
June
30, |
|
|
Increase |
|
|
|
2023 |
|
|
2022 |
|
|
(Decrease) |
|
(in thousands) |
|
|
|
|
|
|
|
|
|
Revenue |
|
$ |
225 |
|
|
|
33 |
|
|
|
192 |
|
Operating expenses: |
|
|
|
|
|
|
|
|
|
|
|
|
R&D |
|
|
1,751 |
|
|
|
1,419 |
|
|
|
332 |
|
General and administrative |
|
|
1,133 |
|
|
|
132 |
|
|
|
1,001 |
|
Total operating expenses |
|
|
2,884 |
|
|
|
1,551 |
|
|
|
1,333 |
|
Loss from operations |
|
|
(2,660 |
) |
|
|
(1,508 |
) |
|
|
(1,142 |
) |
Other income (expense) |
|
|
53 |
|
|
|
(2 |
) |
|
|
55 |
|
Net loss |
|
$ |
(2,607 |
) |
|
|
(1,520 |
) |
|
|
(1,087 |
) |
Grants
and Other Revenue
For the six months ended June
30, 2023, we earned $225,000 in connection with the 2022 NIH Grant, recognized as revenue. We received $33,000 in revenue for
the six months ended June 30, 2022, as the final installment under the previous series of grants awarded by the NIH in 2017 and
2018. We expect to recognize approximately $500,000 from the 2022 NIH Grant in total in the year 2023. The increase
in annual grant revenue from 2022 to 2023 is related to the award of the 2022 NIH Grant.
Operating
Expenses
Research
and Development Expenses
The
following table summarizes our R&D expenses for the six months ended June 30, 2023 and 2022 (in thousands):
| |
Six
Months Ended | | |
| |
| |
June
30, | | |
Increase | |
(in
thousands) | |
2023 | | |
2022 | | |
(Decrease) | |
| |
| | |
| | |
| |
Direct R&D expenses
for the LP-10 product candidate program: | |
| | | |
| | | |
| | |
Employee-related
costs | |
$ | 81 | | |
$ | 253 | | |
$ | (172 | ) |
Employee
stock option expense | |
| 14 | | |
| 304 | | |
| (162 | ) |
Outsourced
R&D | |
| 8 | | |
| 406 | | |
| (324 | ) |
Facility-related
costs | |
| 4 | | |
| 114 | | |
| (71 | ) |
Platform development,
early-stage research and unallocated expenses: | |
| | | |
| | | |
| | |
Employee-related
costs | |
| 29 | | |
| 81 | | |
| 211 | |
Employee
stock option expense | |
| 57 | | |
| 96 | | |
| 478 | |
Outsourced
R&D | |
| 35 | | |
| 106 | | |
| 248 | |
Facility-related
costs | |
| 18 | | |
| 58 | | |
| 125 | |
Total
research and development expenses | |
$ | 1,751 | | |
$ | 1,418 | | |
$ | 333 | |
R&D
expenses increased by approximately $333,000, from $1,418,000 for the six months ended June 30, 2022 to $1,751,000 for the six
months ended June 30, 2023. The increase in R&D expenses was primarily attributable to increases in stock option expense of
$316,000, increased personnel costs (including employee benefits) of $42,000, overhead and facility related costs, including supplies,
of $55,000, and legal patent expense of $12,000. These were partially offset by a reduction in outside services of $88,000 compared to the
same period in the prior year, as the LP-10 clinical trial was still in process in 2022.
General
and Administrative Expenses
General
and administrative expenses were $1,133,000 for the six months ended June 30, 2023, compared to $132,000 for the three months
ended June 30, 2022. General and administrative expenses increased by approximately $1,001,000, including an increase in outside
services costs of $198,000, an increase in franchise tax, licensing, and filing fees of $24,000, and an increase in insurance
expense of $218,000. Additionally, stock option expense increased $292,000, related to our June 2023 option grants, and other
personnel costs (including payroll taxes and benefits) increased approximately $96,000.
Net
Other Income (Expense)
Net other income for
the six months ended June 30, 2023 was $54,000, as compared to a loss of $2,000 for the six months ended June 30, 2022. This balance
primarily included (i) cash interest income, (ii) unrealized loss on investments and (iii) non-cash interest expense on related
party notes. A higher cash investment balance and more favorable rates resulted in an increase of $65,000 in interest receivable
on short term investments in the six months ended June 30, 2023 compared to the same period in the prior year. Meanwhile, interest
expense on related party notes increased by $8,000 due to an increase in the principal of the notes outstanding from $75,000 during
the six months ended June 30, 2022 to $250,000 during the six months ended June 30, 2023. The related party notes were paid in
full on June 30, 2023. See Note 7 of the notes to our unaudited condensed financial statements in this Form 10-Q as well as Note 7 of the notes to
our financial statements in our Annual Report for details of such related party notes and accrued interest at the respective periods.
Liquidity
and Capital Resources
Sources
of Liquidity
We
have not yet commercialized any products, and we do not expect to generate revenue from sales of any product candidates for several
years, if at all. Cash and cash equivalents totaled $3.1 million as of June 30, 2023. We consider all highly liquid investments
that mature in 90 days or less when purchased to be cash equivalents.
We
have incurred operating losses and experienced negative operating cash flows for the six months ended June 30, 2023 and the year
ended December 31, 2022, and we anticipate that we will continue to incur losses for the foreseeable future. Our net loss totaled
$2,606,511 and $1,509,975 for the six months ended June 30, 2023 and 2022, respectively, and $2,597,5692 for the year ended December
31, 2022.
From
inception to date, we have funded our operations primarily through (i) private equity financings (from which we have raised an
aggregate of approximately $11.0 million, (ii) grants received from the U.S. government (from which we have received an aggregate
of approximately $10.1 million, and (iii) the IPO (from which we raised net proceeds of approximately $5.0 million, after deducting
underwriting discounts, commissions, and other offering expenses). Until such time, if ever, as we can generate substantial revenue,
we expect to finance our cash needs through a combination of public or private equity offerings and debt financings or other sources,
such as potential collaboration agreements, strategic alliances and licensing arrangements.
Cash
Flows
The
following table provides information regarding our cash flows for each of the periods presented (in thousands):
|
|
Six
months ended |
|
|
|
June
30, |
|
Dollars
in thousands |
|
2023 |
|
|
2022 |
|
|
|
|
|
|
|
|
Net
cash (used) provided in operating activities |
|
$ |
(1,733 |
) |
|
|
(1,279 |
) |
Net cash (used) provided in investing activities |
|
|
— |
|
|
|
300 |
|
Net cash provided
in financing activities |
|
|
(275 |
) |
|
|
— |
|
Net
increase(decrease) in cash and cash equivalents |
|
$ |
(2,008 |
) |
|
|
(979 |
) |
Net
Cash (Used) Provided in Operating Activities
Net cash used in operating activities for
the six months ended June 30, 2023 was approximately $1,733,000. This comprised a net loss for the period of approximately $2,606,000,
and decreased operating liabilities of $607,000, offset by decreases in the following assets: grants receivable of $86,000 and
prepaid expenses (primarily insurance policies and consulting services) of $339,000. There were also and noncash adjustments to
net loss of $1,056,000 in stock option expense.
Net cash used in operating
activities for the six months ended June 30, 2022 was approximately $1,279,000. This comprised a net loss for the period of approximately
$1,520,000, and increased prepaid expenses of $368,000 (primarily prepaid costs of issuance), partially offset by changes in operating assets
and liabilities of $157,000 and noncash adjustments to net loss of $449,000 in stock option expense and $3,000 in non-cash interest
expense.
Net
Cash (Used) Provided in Investing Activities
Net cash provided by investing activities
for the six months ended June 30, 2023 was $0. For the six months ended June 30, 2022, net cash provided by investing activities
was $300,000, resulting from the sale of short-term, marketable securities.
Net
Cash Used in Financing Activities
Net
cash used in financing activities for the six months ended June 30, 2023 was $275,000. The cash was used to repay a related
party note upon maturity. For the six months ended June 30, 2022, there were no cash flows from financing
activities.
Funding
Requirements
We
expect our expenses to increase substantially in connection with our ongoing R&D activities, particularly as we continue R&D,
advance clinical trials of LP-10 and advance the preclinical development of our other programs, including LP-310. In addition,
we expect to incur additional costs associated with operating as a public company. As a result, we expect to incur substantial
operating losses and negative operating cash flows for the foreseeable future.
Based
on our current operating plan, we believe that our existing cash and cash equivalents will be sufficient to fund our operations
and capital expenses into 2024. However, we have based this estimate on assumptions that may prove to be wrong, and we could exhaust
our capital resources sooner than we expect.
Because
of the numerous risks and uncertainties associated with research, development and commercialization of LP-10, LP-310 and our other
and future product candidates, we are unable to estimate the exact amount of our working capital requirements. Our future funding
requirements will depend on, and could increase significantly as a result of, many factors, including, but not limited to, those
referenced above in “— Results of Operations — Operating Expenses — Research and Development Expenses”.
Going
Concern
The
unaudited condensed financial statements of the Company have been prepared on a going concern basis, which contemplates the realization of assets
and the discharge of liabilities in the normal course of business. We have generated losses from operations since inception. The
Company expects operating losses to continue in the foreseeable future because of additional costs and expenses related to research
and development activities, plans to expand its product portfolio, and increasing its market share. The Company’s ability
to transition to attaining profitable operations is dependent upon achieving a level of revenues adequate to support its cost
structure. The timing and amount of our actual expenditures will be based on many factors, including cash flows from operations
and the anticipated growth of our business.
Management
of the Company may raise additional funds through the issuance of equity securities or debt. There can be no assurance that such
financing will be available at terms acceptable to the Company, if at all. Failure to generate sufficient cash flows from operations
and raise additional capital could have a material adverse effect on the Company’s ability to achieve its intended business
objectives. These factors raise substantial doubt about the Company’s ability to continue as a going concern. The accompanying
unaudited condensed financial statements do not include any adjustments that might be necessary if the Company is unable to continue as a going concern.
Off-Balance
Sheet Arrangements
We
did not have during the six months ended June 30, 2023, or the year ended December 31, 2022, and we do not currently have, any
off-balance sheet arrangements, as defined under applicable SEC rules.
Contractual
Obligations
We
did not have during the six months ended June 30, 2023 or the year ended December 31, 2022, and we do not currently have, any
material contractual obligations, such as license agreements or similar arrangements, other than as described below and in the
financial notes to our unaudited condensed financial statements included in this Form 10-Q and in our Annual Report.
Employment
Agreements
We
are party to employment agreements with each of Drs. Kaufman and Chancellor and Mr. Johnston, executive officers of the Company,
the material terms of each of which are described in the section entitled “Executive Compensation – Executive Employment
Agreements” of our Annual Report and the section entitled “Item 2. Management’s Discussion and Analysis of Financial Condition
and Results of Operations – Recent Developments” of this Form 10-Q.
Lease
Agreement
We
are party to a lease agreement, dated June 1, 2019, with Bridgeway Development Corporation, as amended, for the lease of 2,690
square feet of office and lab and manufacturing space in Pittsburgh, Pennsylvania commencing on July 1, 2020. The current lease
term expires on June 30, 2025 and we have the right to exercise a one-time option to extend the term of the lease for an additional
five-year term. The annual base rent under the lease is approximately $66,000. Also, we are party to the August 2023 Lease, as described in the section entitled “Item 2. Management’s
Discussion and Analysis of Financial Condition and Results of Operations – Recent Developments” of this Form 10-Q.
Service
Agreements
We
enter into service agreements in the normal course of business with CROs and for clinical trials, preclinical research studies
and testing, manufacturing, and other services and products for operating purposes. These contracts do not contain any minimum
purchase commitments. Certain agreements provide for termination rights subject to termination fees or wind down costs. Under
such agreements, we are contractually obligated to make certain payments to vendors, mainly to reimburse them for their unrecoverable
outlays incurred prior to cancellation. The exact amounts of such obligations are dependent on the timing of termination, and
the exact terms of the relevant agreement and cannot be reasonably estimated. The expense we incurred pursuant to these agreements
for the six months ended June 30, 2023 was approximately $435,000, compared to approximately $314,000 for the six months ended
June 30, 2022. The increase was due to early stage research for our LP-310 oral liquid protocol.
Critical
Accounting Policies and Significant Judgments and Estimates
This
management’s discussion and analysis is based on our unaudited condensed financial statements, which have been prepared in accordance with GAAP.
The preparation of these financial statements requires us to make judgments and estimates that affect the reported amounts of
assets and liabilities, the disclosure of contingent assets and liabilities at the date of the unaudited condensed financial statements and the reported
amounts of expenses during the reported periods. We base our estimates on historical experience, known trends and events, and
various other factors that we believe to be reasonable under the circumstances. Actual results may differ from these estimates
under different assumptions or conditions. On an ongoing basis, we evaluate our judgments and estimates in light of changes in
circumstances, facts and experience. The effects of material revisions in estimates, if any, will be reflected in the financial
statements prospectively from the date of change in estimates.
While
our accounting policies are described in more detail in the notes to our financial statements included in our Annual Report, we
believe the following accounting policies used in the preparation of our financial statements require the most significant judgments
and estimates. See Note 3 in our Annual Report for a description of our other significant accounting policies.
Accrued
Expenses
As
part of the process of preparing our financial statements, we are required to estimate our accrued third-party R&D expenses
as of each balance sheet date. This process involves reviewing open contracts and purchase orders, communicating with our personnel
to identify services that have been performed on our behalf, and estimating the level of service performed and the associated
cost incurred for the service when we have not yet been invoiced or otherwise notified of the actual cost. The majority of our
service providers invoice us monthly in arrears for services performed or when contractual milestones are met. We make estimates
of our accrued expenses as of each balance sheet date based on facts and circumstances known to us at that time. We periodically
confirm the accuracy of our estimates with the service providers and make adjustments if necessary. The significant estimates
in our accrued R&D expenses include the costs incurred for services performed by our vendors in connection with R&D activities
for which we have not yet been invoiced.
We
base our expenses related to R&D activities on our estimates of the services received and efforts expended pursuant to quotes
and contracts with vendors that conduct R&D activities on our behalf. The financial terms of these agreements are subject
to negotiation, vary from contract to contract and may result in uneven payment flows. There may be instances in which payments
made to our vendors will exceed the level of services provided and result in a prepayment of the R&D expense. In accruing
service fees, we estimate the time period over which services will be performed and the level of effort to be expended in each
period. If the actual timing of the performance of services or the level of effort varies from our estimate, we adjust the accrual
or prepaid balance accordingly. Non-refundable advance payments for goods and services that will be used in future R&D activities
are expensed when the activity has been performed or when the goods have been received rather than when the payment is made.
Although
we do not expect our estimates to be materially different from amounts incurred, if our estimates of the status and timing of
services performed differ from the actual status and timing of services performed, it could result in us reporting amounts that
are too high or too low in any particular period. To date, there have been no material differences between our estimates of such
expenses and the amounts incurred.
Stock-Based
Compensation
We
measure stock-based compensation based on the grant date fair value of the stock-based awards and recognize stock-based compensation
expense on a straight-line basis over the requisite service period of the awards, which is generally the vesting period of the
respective award. For non-employee awards, compensation expense is recognized as the services are provided, which is generally
ratably over the vesting period. We account for forfeitures as they occur. On January 1, 2018, we adopted, using the modified
retroactive approach, the guidance of Accounting Standard Update 2018-07, Compensation — Stock Compensation (Topic 718)
— Improvements to Nonemployee Share-Based Payment Accounting (“ASU 2018-07”), and account for awards to
non-employees using the grant date fair value without subsequent periodic remeasurement. The adoption of ASU 2018-07 did not have
a material effect on our financial statements.
We
classify stock-based compensation expense in our statements of operations in the same manner in which the award recipient’s
salary and related costs are classified or in which the award recipient’s service payments are classified. In future periods,
we expect stock-based compensation expense to increase, due in part to our existing unrecognized stock-based compensation expense
and as we grant additional stock-based awards to continue to attract and retain our employees.
We
determine the fair value of restricted Common Stock awards granted based on the fair value of our Common Stock. We have historically
determined the fair value of the underlying Common Stock based on input from management and the board of directors and the Company’s
enterprise value determined utilizing various methods, including the “back-solve” method. The total enterprise value,
determined from the back-solve method, is historically then allocated to the various outstanding equity instruments, including
the underlying Common Stock, utilizing the option pricing method (“OPM”) or a hybrid of the probability-weighted expected
return method (“PWERM”) and the OPM.
The
fair value of each stock option grant is estimated on the date of grant using the Black-Scholes option-pricing model, which requires
inputs based on certain subjective assumptions, including the expected stock price volatility, the expected term of the option,
the risk-free interest rate for a period that approximates the expected term of the option, and our expected dividend yield. As
the public market for our Common Stock has been limited and prior to the IPO there was no such public market, we have historically
determined the volatility for awards granted based on an analysis of reported data for a group of guideline companies that issued
options with substantially similar terms. The expected volatility has been determined using a weighted-average of the historical
volatility measures of this group of guideline companies along with our own. We expect to continue estimating expected volatility
based on the group of guideline companies until we have adequate historical data regarding the volatility of our own traded stock
price. The expected term of our stock options granted to employees and non-employees has been determined utilizing the “simplified”
method for awards that qualify as “plain-vanilla” options. The risk-free interest rate is determined by reference
to the U.S. Treasury yield curve in effect at the time of grant of the award for time periods approximately equal to the expected
term of the award. We have not paid, and do not anticipate paying, dividends on our Common Stock; therefore, the expected dividend
yield is assumed to be zero.
As
there was no public market for our Common Stock prior to the IPO, the estimated fair value of our Common Stock prior to our IPO
had been approved by our board of directors, with input from management, as of the date of each award grant, considering our most
recently available independent third-party valuations of our Common Stock and any additional objective and subjective factors
that we believed were relevant and which may have changed from the date of the most recent valuation through the date of each
award grant. We estimated the value of our equity using the market approach and a precedent transaction method which “back-solves”
the equity value that yielded a specific value for our Series A Stock. We allocated the equity value to our Common Stock and shares
of our Series A Stock using either an OPM or a hybrid method, which is a hybrid between the OPM and the PWERM. The hybrid method
we utilized estimated the probability-weighted value across multiple scenarios but used the OPM to estimate the allocation of
value within at least one of the scenarios. In addition to the OPM, the hybrid method considered the IPO scenario in which the
shares of our Series A Stock converted to Common Stock. The future value of the Common Stock in the IPO scenario was discounted
back to the valuation date at an appropriate risk adjusted discount rate. In the hybrid method, the present value indicated for
each scenario was probability weighted to arrive at an indication of value for our Common Stock.
In
addition to considering the results of the valuations, management considered various objective and subjective factors to determine
the fair value of our Common Stock as of each grant date, which may be a date later than the most recent third-party valuation
date, including:
|
● |
the prices of our
Series A Stock sold to or exchanged between outside investors in arm’s length transactions, if any, and the rights,
preferences and privileges of our Series A Stock as compared to those of our Common Stock, including the liquidation preferences
of our Series A Stock; |
|
● |
the progress of
our R&D efforts, including the status of preclinical studies; |
|
● |
the lack of liquidity
of our equity as a private company; |
|
● |
our stage of development
and business strategy and the material risks related to our business and industry; |
|
● |
the achievement
of enterprise milestones; |
|
● |
the valuation of
publicly traded companies in the life sciences and biotechnology sectors, as well as recently completed mergers and acquisitions
of peer companies; |
|
● |
any external market
conditions affecting the biotechnology industry, and trends within the biotechnology industry; |
|
● |
the likelihood of
achieving a liquidity event for the holders of our Series A Stock and Common Stock, such as an IPO, or a sale of the Company,
given prevailing market conditions; and |
|
● |
the analysis of
IPOs and the market performance of similar companies in the biopharmaceutical industry. |
There
are significant judgments and estimates inherent in these valuations. These judgments and estimates included assumptions regarding
our future operating performance, the stage of development of our programs, the timing of a potential offering, or other liquidity
event, and the determination of the appropriate valuation methodology at each valuation date. The assumptions underlying these
valuations represented management’s best estimates, which involve inherent uncertainties and the application of management
judgment. As a result, if factors or expected outcomes change and we use significantly different assumptions or estimates, our
stock-based compensation expense could be materially different. Subsequent to the completion of the IPO, the fair value of our
Common Stock is determined based on the market price of our Common Stock on Nasdaq.
With
respect to stock options granted during the six months ended June 30, 2023 and 2022, the following table sets forth by grant date,
after giving effect to the Stock Split, the (i) number of shares of our Common Stock issuable upon exercise of such stock options,
(ii) per share exercise price of such options and (iii) estimated fair value per share of our Common Stock on each such date.
We did not grant any shares of restricted Common Stock during this period.
Grant
date |
|
Number
of shares of Common
Stock
issuable upon exercise of
stock
options granted |
|
|
Exercise
price per
share
of Common
Stock |
|
|
Estimated
fair value per
share
of Common Stock
at
grant date |
|
03/01/22 |
|
|
10,000 |
|
|
$ |
5.00 |
|
|
$ |
2.84 |
|
06/16/23 |
|
|
424,000 |
|
|
$ |
2.19 |
|
|
$ |
1.50 |
|
The
per share values at each such grant date, which we applied to determine the per share estimated fair value of the respective awards
for accounting purposes, were based upon the calculations described above used to determine the fair value of our Common Stock
as of each grant date.
Emerging
Growth Company Status
In
April 2012, the Jumpstart Our Business Startups Act of 2012 (the “JOBS Act”) was enacted. Section 107 of the JOBS
Act provides that an “emerging growth company” may take advantage of the extended transition period provided in Section
7(a)(2)(B) of the Securities Act for complying with new or revised accounting standards. Therefore, an emerging growth company
can delay the adoption of certain accounting standards until those standards would otherwise apply to private companies. We have
irrevocably elected to avail ourselves of this extended transition period and, as a result, we will not be required to adopt new
or revised accounting standards on the relevant dates on which adoption of such standards is required for other public companies.
In
addition, as an emerging growth company, we may take advantage of specified reduced disclosure and other requirements that are
otherwise applicable generally to public companies. These provisions include, among other things:
|
● |
reduced disclosure
about the compensation paid to our executive officers; |
|
|
|
|
● |
not being required
to submit to our stockholders’ advisory votes on executive compensation or golden parachute arrangements; |
|
|
|
|
● |
an exemption from
the auditor attestation requirement in the pursuant to the Sarbanes-Oxley Act of 2002; and |
|
|
|
|
● |
an exemption from
compliance with any new requirements adopted by the Public Company Accounting Oversight Board requiring mandatory audit firm
rotation. |
We
may take advantage of these exemptions until such time that we are no longer an emerging growth company. We would cease to be
an emerging growth company upon the earliest of
|
● |
the last day of
the fiscal year on which we have $1.235 billion or more in annual revenue, |
|
|
|
|
● |
the date on which
we become a “large accelerated filer” (i.e., as of our fiscal year end, the total market value of our common equity
securities held by non-affiliates is $700 million or more as of June 30), |
|
|
|
|
● |
the date on which
we issue more than $1.0 billion of non-convertible debt over a three-year period, or |
|
|
|
|
● |
the last day of
our fiscal year following the fifth anniversary of the date of the completion of the IPO. |
We
may choose to take advantage of some but not all of these exemptions.
Recent
Accounting Pronouncements
We
have reviewed all recently issued accounting pronouncements and have determined that, other than as disclosed in Note 3 to our
unaudited condensed financial statements included in this Report, such standards will not have a material impact on our financial
statements or do not otherwise apply to our operations.
Item
3. Quantitative and Qualitative Disclosures about Market Risk.
As
a smaller reporting company, as defined in Item 10(f)(1) of Regulation S-K, we are not required to provide the information required
by this Item.
Item
4. Controls and Procedures.
Evaluation
of Disclosure Controls and Procedures
Under
the supervision and with the participation of our management, including the Chief Executive Officer and Chief Financial Officer,
the Company conducted an evaluation of the effectiveness of its disclosure controls and procedures (as such term is defined in
Rules 13a-15(e) and 15d-15(e) under the Exchange Act as of the end of the period covered by this report. Disclosure controls and
procedures are designed to ensure that information required to be disclosed in the reports the Company files or submits under
the Exchange Act is recorded, processed, summarized and reported within the time periods specified in the SEC’s rules and
forms and that such information is accumulated and communicated to management, including the Chief Executive Officer and Chief
Financial Officer, to allow timely decisions regarding required disclosure. Based on this evaluation, the Company’s management,
including the Chief Executive Officer and Chief Financial Officer, concluded that its disclosure controls and procedures were
effective as of June 30, 2023.
Changes
in Internal Controls
There
were no changes in the Company’s internal control over financial reporting (as defined in Rules 13a-15(f) and 15d-15(f))
that occurred during the three or six months ended June 30, 2023, that have materially affected or are reasonably likely to materially
affect our internal control over financial reporting.
Limitations
of the Effectiveness of Controls
Our
management, including our Chief Executive Officer and Chief Financial Officer, does not expect that our disclosure controls and
procedures will prevent all errors and all fraud. A control system, no matter how well conceived and operated, can provide only
reasonable, not absolute, assurance that the objectives of the control system are met. Further, the design of a control system
must reflect the fact that there are resource constraints, and the benefits of controls must be considered relative to their costs.
Because of the inherent limitations in all control systems, no evaluation of controls can provide absolute assurance that all
control issues and instances of fraud, if any, have been detected. These inherent limitations include, but are not limited to,
the realities that judgments in decision making can be faulty and that breakdowns can occur because of simple errors. Additionally,
controls can be circumvented by the individual acts of some persons, by collusion of two or more people, or by management override
of the control. The design of any system of controls is also based in part upon certain assumptions about the likelihood of future
events, and there can be no assurance that any design will succeed in achieving its stated goals under all potential future conditions.
Because of the inherent limitations in a cost-effective control system, misstatements due to error or fraud may occur and not
be detected.
PART
II. OTHER INFORMATION
Item
1. Legal Proceedings.
From
time to time, we may become subject to legal proceedings, claims or litigation arising in the ordinary course of business. We
are not presently a party to any legal proceedings that in the opinion of our management, if determined adversely to us, would
individually or taken together have a material adverse effect on our business, operating results, financial condition or cash
flows.
Item
1A. Risk Factors.
As
a smaller reporting company, as defined in Item 10(f)(1) of Regulation S-K, we are not required to provide the information required
by this Item.
Item
2. Unregistered Sales of Equity Securities and Use of Proceeds.
None.
Item
3. Defaults Upon Senior Securities.
None.
Item
4. Mine Safety Disclosures.
Not
applicable.
Item
5. Other Information.
None.
Item
6. Exhibits.
In
accordance with SEC Release 33-8238, Exhibits 32.1 and 32.2 are being furnished and not filed.
SIGNATURES
Pursuant
to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf
by the undersigned, thereunto duly authorized.
|
Lipella Pharmaceuticals Inc. |
|
|
|
Date: August 14, 2023 |
By: |
/s/
Jonathan Kaufman |
|
|
Jonathan Kaufman |
|
|
President and Chief Executive Officer |
|
|
(Duly Authorized Officer and Principal Executive
Officer) |
|
|
|
Date: August 14, 2023 |
By: |
/s/
Douglas Johnston |
|
|
Douglas Johnston |
|
|
Chief Financial Officer |
|
|
(Duly Authorized Officer and Principal Financial
and Accounting Officer) |
Exhibit
31.1
CERTIFICATION
OF
PRINCIPAL EXECUTIVE OFFICER
PURSUANT
TO 18 U.S.C. SECTION 1350,
AS
ADOPTED PURSUANT TO SECTION 302 OF
THE
SARBANES-OXLEY ACT OF 2002
I,
Jonathan Kaufman, as the principal executive officer of the registrant, certify that:
1.
I have reviewed this quarterly report on Form 10-Q for the quarter ended June 30, 2023, of Lipella Pharmaceuticals Inc.;
2.
Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary
to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect
to the period covered by this report;
3.
Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all
material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods
presented in this report;
4.
The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and
procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined
in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:
a. Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision,
to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by
others within those entities, particularly during the period in which this report is being prepared;
b.
Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed
under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of
financial statements for external purposes in accordance with generally accepted accounting principles;
c. Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions
about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on
such evaluation; and
d.
Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the
registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that
has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial
reporting; and
5.
The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control
over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors
(or persons performing the equivalent functions):
a.
All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which
are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information;
and
b.
Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s
internal control over financial reporting.
Date: August 14, 2023 |
By: |
/s/
Jonathan Kaufman |
|
|
Jonathan Kaufman |
|
|
Chief Executive Officer |
|
|
(Duly Authorized Officer and Principal Executive
Officer) |
Exhibit
31.2
CERTIFICATION
OF
PRINCIPAL FINANCIAL OFFICER
PURSUANT
TO 18 U.S.C. SECTION 1350,
AS
ADOPTED PURSUANT TO SECTION 302 OF
THE
SARBANES-OXLEY ACT OF 2002
I,
Douglas Johnston, as the principal financial officer of the registrant, certify that:
1.
I have reviewed this quarterly report on Form 10-Q for the quarter ended June 30, 2023, of Lipella Pharmaceuticals Inc.;
2.
Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary
to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect
to the period covered by this report;
3.
Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all
material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods
presented in this report;
4.
The registrant’s other certifying officer and I are responsible for establishing and maintaining disclosure controls and
procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined
in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:
a. Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision,
to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by
others within those entities, particularly during the period in which this report is being prepared;
b.
Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed
under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of
financial statements for external purposes in accordance with generally accepted accounting principles;
c. Evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions
about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on
such evaluation; and
d.
Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the
registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that
has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial
reporting; and
5.
The registrant’s other certifying officer and I have disclosed, based on our most recent evaluation of internal control
over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors
(or persons performing the equivalent functions):
a.
All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which
are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information;
and
b.
Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s
internal control over financial reporting.
Date: August 14, 2023 |
By: |
/s/
Douglas Johnston |
|
|
Douglas Johnston |
|
|
Chief Financial Officer |
|
|
(Duly
Authorized Officer and Principal Financial and Accounting Officer) |
Exhibit
32.1
CERTIFICATION
OF
PRINCIPAL EXECUTIVE OFFICER
PURSUANT
TO 18 U.S.C. SECTION 1350,
AS
ADOPTED PURSUANT TO SECTION 906 OF
THE
SARBANES-OXLEY ACT OF 2002
In
connection with the Quarterly Report of Lipella Pharmaceuticals Inc. (the “Company”) on Form 10-Q for the quarter
ended June 30, 2023, as filed with the Securities and Exchange Commission on the date hereof (the “Report”), I, Jonathan
Kaufman, Chief Executive Officer of the Company, certify, pursuant to 18 U.S.C. §1350, as adopted pursuant to Section 906
of the Sarbanes-Oxley Act of 2002, that:
|
(1) |
The Report fully
complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934; and |
|
|
|
|
(2) |
The
information contained in the Report fairly presents, in all material respects, the financial condition and results of operations
of the Company. |
|
|
|
Date: August 14, 2023 |
By: |
/s/
Jonathan Kaufman |
|
|
Jonathan Kaufman |
|
|
Chief Executive Officer |
|
|
(Principal Executive Officer) |
Exhibit
32.2
CERTIFICATION
OF
PRINCIPAL FINANCIAL OFFICER
PURSUANT
TO 18 U.S.C. SECTION 1350,
AS
ADOPTED PURSUANT TO SECTION 906 OF
THE
SARBANES-OXLEY ACT OF 2002
In
connection with the Quarterly Report of Lipella Pharmaceuticals Inc. (the “Company”) on Form 10-Q for the quarter
ended June 30, 2023, as filed with the Securities and Exchange Commission on the date hereof (the “Report”), I, Douglas
Johnston, Chief Financial Officer of the Company, certify, pursuant to 18 U.S.C. §1350, as adopted pursuant to Section 906
of the Sarbanes-Oxley Act of 2002, that:
|
(1) |
The Report fully
complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934; and |
|
|
|
|
(2) |
The
information contained in the Report fairly presents, in all material respects, the financial condition and results of operations
of the Company. |
|
|
|
Date: August 14, 2023 |
By: |
/s/
Douglas Johnston |
|
|
Douglas Johnston |
|
|
Chief Financial Officer |
|
|
(Principal Financial and Accounting Officer) |
v3.23.2
Cover - shares
|
6 Months Ended |
|
Jun. 30, 2023 |
Aug. 11, 2023 |
Cover [Abstract] |
|
|
Document Type |
10-Q
|
|
Amendment Flag |
false
|
|
Document Quarterly Report |
true
|
|
Document Transition Report |
false
|
|
Document Period End Date |
Jun. 30, 2023
|
|
Document Fiscal Period Focus |
Q2
|
|
Document Fiscal Year Focus |
2023
|
|
Current Fiscal Year End Date |
--12-31
|
|
Entity File Number |
001-41575
|
|
Entity Registrant Name |
Lipella
Pharmaceuticals Inc.
|
|
Entity Central Index Key |
0001347242
|
|
Entity Tax Identification Number |
20-2388040
|
|
Entity Incorporation, State or Country Code |
DE
|
|
Entity Address, Address Line One |
7800
Susquehanna St.
|
|
Entity Address, Address Line Two |
Suite 505
|
|
Entity Address, City or Town |
Pittsburgh
|
|
Entity Address, State or Province |
PA
|
|
Entity Address, Postal Zip Code |
15208
|
|
City Area Code |
(412)
|
|
Local Phone Number |
901-0315
|
|
Title of 12(b) Security |
Common Stock, par
value $0.0001 per share
|
|
Trading Symbol |
LIPO
|
|
Security Exchange Name |
NASDAQ
|
|
Entity Current Reporting Status |
Yes
|
|
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Yes
|
|
Entity Filer Category |
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|
|
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true
|
|
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true
|
|
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v3.23.2
CONDENSED BALANCE SHEETS (unaudited) - USD ($)
|
Jun. 30, 2023 |
Dec. 31, 2022 |
Current Assets |
|
|
Cash and cash equivalents |
$ 3,113,644
|
$ 5,121,743
|
Grants receivable |
28,044
|
113,655
|
Prepaid expenses |
225,302
|
563,891
|
Total Current Assets |
3,366,990
|
5,799,289
|
Operating lease right of use asset |
122,546
|
150,821
|
Total Assets |
3,489,536
|
5,950,110
|
Current liabilities |
|
|
Accounts payable |
22,057
|
384,357
|
Accrued expenses |
138,704
|
389,209
|
Operating lease liability |
60,788
|
58,262
|
Payroll liability |
77,255
|
67,832
|
Notes payable, current |
|
25,000
|
Related party loan |
|
250,000
|
Related party interest |
|
3,596
|
Total Current Liabilities |
298,804
|
1,178,256
|
Operating lease liability, net of current portion |
65,390
|
96,258
|
Total Liabilities |
364,194
|
1,274,514
|
Stockholders' equity: |
|
|
Preferred stock, $0.0001 par value; 20,000,000 shares authorized; 0 shares outstanding at June 30, 2023 and December 31, 2022 |
|
|
Common stock, $0.0001 par value; 200,000,000 shares authorized; 5,743,945 shares issued and outstanding at June 30, 2023 and December 31, 2022 |
574
|
574
|
Additional paid-in capital |
11,436,157
|
10,379,900
|
Accumulated deficit |
(8,311,389)
|
(5,704,878)
|
Total stockholders' equity |
3,125,342
|
4,675,596
|
Total liabilities and stockholders' equity |
$ 3,489,536
|
$ 5,950,110
|
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v3.23.2
CONDENSED BALANCE SHEETS (unaudited) (Parenthetical) - $ / shares
|
Jun. 30, 2023 |
Dec. 31, 2022 |
Statement of Financial Position [Abstract] |
|
|
Preferred stock, par value (in dollars per share) |
$ 0.0001
|
$ 0.0001
|
Preferred stock, shares authorized |
20,000,000
|
20,000,000
|
Preferred stock, shares outstanding |
0
|
0
|
Common stock, par value (in dollars per share) |
$ 0.0001
|
$ 0.0001
|
Common stock, shares authorized |
200,000,000
|
200,000,000
|
Common stock, shares outstanding |
5,743,945
|
5,743,945
|
Common stock, shares issued |
5,743,945
|
5,743,945
|
X |
- DefinitionFace amount or stated value per share of common stock.
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v3.23.2
CONDENSED STATEMENTS OF OPERATIONS (Unaudited) - USD ($)
|
3 Months Ended |
6 Months Ended |
Jun. 30, 2023 |
Jun. 30, 2022 |
Jun. 30, 2023 |
Jun. 30, 2022 |
Total revenues |
$ 106,676
|
|
$ 224,724
|
$ 33,149
|
Cost and expenses |
|
|
|
|
Research and development |
1,057,645
|
742,660
|
1,751,376
|
1,418,622
|
General and administrative |
624,231
|
38,487
|
1,132,980
|
132,337
|
Total costs and expenses |
1,681,876
|
781,147
|
2,884,356
|
1,550,959
|
Loss from operations |
(1,575,200)
|
(781,147)
|
(2,659,632)
|
(1,517,810)
|
Other income (expense) |
|
|
|
|
Other income (expense) |
|
156
|
|
(45)
|
Interest income |
41,968
|
603
|
63,969
|
1,134
|
Interest expense related party |
(5,454)
|
(1,636)
|
(10,848)
|
(3,254)
|
Total other income/(expense) |
36,514
|
(877)
|
53,121
|
(2,165)
|
Loss before income taxes |
(1,538,686)
|
(782,024)
|
(2,606,511)
|
(1,519,975)
|
Provision for income taxes |
|
|
|
|
Net Loss |
$ (1,538,686)
|
$ (782,024)
|
$ (2,606,511)
|
$ (1,519,975)
|
Loss per share of Common Stock |
|
|
|
|
Basic |
$ (0.27)
|
$ (0.20)
|
$ (0.45)
|
$ (0.39)
|
Dilutive |
$ (0.27)
|
$ (0.20)
|
$ (0.45)
|
$ (0.39)
|
Weighted-average of shares of Common Stock outstanding: |
|
|
|
|
Basic |
5,743,945
|
3,866,625
|
5,743,945
|
3,866,625
|
Dilutive |
5,743,945
|
3,866,625
|
5,743,945
|
3,866,625
|
Grant revenues [Member] |
|
|
|
|
Total revenues |
$ 106,676
|
|
$ 224,724
|
$ 33,149
|
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v3.23.2
CONDENSED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY (Unaudited) - USD ($)
|
Series A Convertible Preferred Stocks [Member] |
Common Stock [Member] |
Additional Paid-in Capital [Member] |
Retained Earnings [Member] |
Total |
Beginning balance, value at Dec. 31, 2021 |
$ 159
|
$ 387
|
$ 4,530,193
|
$ (3,107,187)
|
$ 1,423,552
|
Balance at beginning (in shares) at Dec. 31, 2021 |
1,592,447
|
3,866,625
|
|
|
|
Net loss |
|
|
|
(737,950)
|
(737,950)
|
Issuance of stock options |
|
|
235,148
|
|
235,148
|
Ending balance, value at Mar. 31, 2022 |
$ 159
|
$ 387
|
4,765,341
|
(3,845,137)
|
920,750
|
Balance at ending (in shares) at Mar. 31, 2022 |
1,592,447
|
3,866,625
|
|
|
|
Beginning balance, value at Dec. 31, 2021 |
$ 159
|
$ 387
|
4,530,193
|
(3,107,187)
|
1,423,552
|
Balance at beginning (in shares) at Dec. 31, 2021 |
1,592,447
|
3,866,625
|
|
|
|
Net loss |
|
|
|
|
(1,519,975)
|
Ending balance, value at Jun. 30, 2022 |
$ 159
|
$ 387
|
4,978,830
|
(4,627,161)
|
352,215
|
Balance at ending (in shares) at Jun. 30, 2022 |
1,592,447
|
3,866,625
|
|
|
|
Beginning balance, value at Dec. 31, 2021 |
$ 159
|
$ 387
|
4,530,193
|
(3,107,187)
|
1,423,552
|
Balance at beginning (in shares) at Dec. 31, 2021 |
1,592,447
|
3,866,625
|
|
|
|
Net loss |
|
|
|
|
(2,597,692)
|
Ending balance, value at Dec. 31, 2022 |
|
$ 574
|
10,379,900
|
(5,704,878)
|
4,675,596
|
Balance at ending (in shares) at Dec. 31, 2022 |
|
5,743,945
|
|
|
|
Beginning balance, value at Mar. 31, 2022 |
$ 159
|
$ 387
|
4,765,341
|
(3,845,137)
|
920,750
|
Balance at beginning (in shares) at Mar. 31, 2022 |
1,592,447
|
3,866,625
|
|
|
|
Net loss |
|
|
|
(782,024)
|
(782,024)
|
Issuance of stock options |
|
|
213,489
|
|
213,489
|
Ending balance, value at Jun. 30, 2022 |
$ 159
|
$ 387
|
4,978,830
|
(4,627,161)
|
352,215
|
Balance at ending (in shares) at Jun. 30, 2022 |
1,592,447
|
3,866,625
|
|
|
|
Beginning balance, value at Dec. 31, 2022 |
|
$ 574
|
10,379,900
|
(5,704,878)
|
4,675,596
|
Balance at beginning (in shares) at Dec. 31, 2022 |
|
5,743,945
|
|
|
|
Net loss |
|
|
|
(1,067,825)
|
(1,067,825)
|
Issuance of stock options |
|
|
208,639
|
|
208,639
|
Ending balance, value at Mar. 31, 2023 |
|
$ 574
|
10,588,539
|
(6,772,703)
|
3,816,410
|
Balance at ending (in shares) at Mar. 31, 2023 |
|
5,743,945
|
|
|
|
Beginning balance, value at Dec. 31, 2022 |
|
$ 574
|
10,379,900
|
(5,704,878)
|
4,675,596
|
Balance at beginning (in shares) at Dec. 31, 2022 |
|
5,743,945
|
|
|
|
Net loss |
|
|
|
|
(2,606,511)
|
Ending balance, value at Jun. 30, 2023 |
|
$ 574
|
11,436,157
|
(8,311,389)
|
3,125,342
|
Balance at ending (in shares) at Jun. 30, 2023 |
|
5,743,945
|
|
|
|
Beginning balance, value at Mar. 31, 2023 |
|
$ 574
|
10,588,539
|
(6,772,703)
|
3,816,410
|
Balance at beginning (in shares) at Mar. 31, 2023 |
|
5,743,945
|
|
|
|
Net loss |
|
|
|
(1,538,686)
|
(1,538,686)
|
Issuance of stock options |
|
|
847,618
|
|
847,618
|
Ending balance, value at Jun. 30, 2023 |
|
$ 574
|
$ 11,436,157
|
$ (8,311,389)
|
$ 3,125,342
|
Balance at ending (in shares) at Jun. 30, 2023 |
|
5,743,945
|
|
|
|
X |
- DefinitionThe portion of profit or loss for the period, net of income taxes, which is attributable to the parent.
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v3.23.2
CONDENSED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($)
|
6 Months Ended |
Jun. 30, 2023 |
Jun. 30, 2022 |
Cash flow from operating activities: |
|
|
Net loss |
$ (2,606,511)
|
$ (1,519,975)
|
Adjustments to reconcile net loss to net cash provided by (used in) operating activities: |
|
|
Non-cash stock option expense |
1,056,257
|
448,637
|
Interest expense related party net (non-cash) |
|
3,254
|
Changes in operating assets and liabilities: |
|
|
Operating right of use asset |
(67)
|
582
|
Grants receivable |
85,611
|
|
Prepaid expense |
338,589
|
(368,334)
|
Accounts payable |
(362,300)
|
8,583
|
Accrued expenses |
(254,101)
|
146,918
|
Payroll liability |
9,423
|
944
|
Net cash used in operating activities |
(1,733,099)
|
(1,279,391)
|
Cash flow from investing activities: |
|
|
Purchase or sale of marketable securities |
|
300,546
|
Net cash provided by investing activities |
|
300,546
|
Cash flow from financing activities: |
|
|
Repayment of notes payable |
(275,000)
|
|
Net cash used in financing activities |
(275,000)
|
|
Net decrease in cash, cash equivalents |
(2,008,099)
|
(978,845)
|
Cash, and cash equivalents at beginning of period |
5,121,743
|
1,413,828
|
Cash, and cash equivalents at end of period |
3,113,644
|
434,983
|
Supplemental disclosure of cash flow information: |
|
|
Interest Paid |
(10,338)
|
|
Income taxes paid |
|
|
Issuance of Common Stock for forgiveness of related party note |
|
|
Exercise of Common Stock options for consulting services |
|
|
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v3.23.2
Description of Business and Basis of Presentation
|
6 Months Ended |
Jun. 30, 2023 |
Accounting Policies [Abstract] |
|
Description of Business and Basis of Presentation |
Note 1. Description of Business and Basis of Presentation
Nature of Business
Lipella Pharmaceuticals Inc. (the “Company”) is focused on the development of drugs, diagnostics,
and medical devices. Our operations consist of research, preclinical development and clinical development activities, and our most
advanced program is in Phase 2a clinical development. Since our inception in 2005, we have historically financed our operations
through a combination of federal grant revenue, licensing revenue, manufacturing revenue, as well as equity and debt financing.
The Company is located in Pittsburgh, PA. On December 19, 2022, we effected the Stock Split. The Company’s outstanding
share and per share amounts in these condensed financial statements have been adjusted to give effect to the Stock Split, for all periods
presented. For more information, see Note 11 - Common Stock.
Basis of Presentation
The
Company’s unaudited condensed financial statements have been prepared in accordance with U.S. generally accepted accounting
principles (“GAAP”). Any reference in these notes to applicable guidance is meant to refer to the authoritative GAAP
as found in the Accounting Standards Codification (“ASC”) and Accounting Standards Updates (“ASU”) of the
Financial Accounting Standards Board (“FASB”).
In the opinion of management,
the accompanying unaudited condensed financial statements include all adjustments, consisting of normal recurring
adjustments, which are necessary to present fairly the Company’s financial position, results of operations, and cash flows.
The interim results of operations are not necessarily indicative of the results that may occur for the full fiscal year. Certain
information and footnote disclosure normally included in the financial statements prepared in accordance with GAAP have been condensed
or omitted pursuant to instructions, rules, and regulations prescribed by the United States Securities and Exchange Commission
(“SEC”). The unaudited condensed interim financial statements should be read in conjunction with the audited financial statements
and notes thereto included in our Annual Report on Form 10-K for the year ended December 31, 2022 that was filed with
the SEC on March 31, 2023 (our “Annual Report”).
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- DefinitionThe entire disclosure for the business description and basis of presentation concepts. Business description describes the nature and type of organization including but not limited to organizational structure as may be applicable to holding companies, parent and subsidiary relationships, business divisions, business units, business segments, affiliates and information about significant ownership of the reporting entity. Basis of presentation describes the underlying basis used to prepare the financial statements (for example, US Generally Accepted Accounting Principles, Other Comprehensive Basis of Accounting, IFRS).
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v3.23.2
Going Concern
|
6 Months Ended |
Jun. 30, 2023 |
Organization, Consolidation and Presentation of Financial Statements [Abstract] |
|
Going Concern |
Note 2. Going Concern
The accompanying condensed financial
statements have been prepared in conformity with GAAP, which contemplate continuation of the Company as a going concern. The Company
has not established a source of revenues sufficient to cover its operating costs and will require significant additional capital
to continue its research and development programs, including progressing clinical product candidates to commercialization and
preparing for commercial-scale manufacturing and sales.
The Company’s net loss
for the six months ended June 30, 2023 and fiscal year ended December 31, 2022 was ($2,606,511) and ($2,597,692), respectively.
Since inception, the Company has incurred historical losses and has an accumulated deficit of ($8,311,389) at June 30, 2023 and
($5,704,878) at December 31, 2022, respectively. At June 30, 2023, the Company had available cash and cash equivalents of $3,113,644
and net working capital of $3,068,186. The Company anticipates operating losses to continue for the foreseeable future
due to, among other things, costs related to: research, development of product candidates, conducting preclinical studies
and clinical trials, and administrative organization. These funds, and our funds available under existing government contracts,
may not be sufficient to enable us to meet our obligations as they come due at least for the next twelve months from the issuance
date of these financial statements.
If we are unable to
obtain additional capital (which is not assured at this time), our long-term business plan may not be accomplished and we may be
forced to curtail or cease operations. These factors individually and collectively raise substantial doubt about our ability to
continue as a going concern. The accompanying unaudited condensed financial statements do not include any adjustments that may result from this uncertainty.
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v3.23.2
Summary of Significant Accounting Policies
|
6 Months Ended |
Jun. 30, 2023 |
Accounting Policies [Abstract] |
|
Summary of Significant Accounting Policies |
Note 3. Summary of Significant Accounting Policies
Use of Estimates
The preparation of
financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts
of assets and liabilities and disclosure of contingent assets and liabilities at the date of these financial statements. Actual
results could differ from those estimates.
Basis of Presentation
The unaudited condensed
financial statements have been prepared in accordance with GAAP for interim financial information and Article 10 of Regulation
S-X. Accordingly, the unaudited condensed financial statements do not include all of the information and footnotes required by
GAAP for complete financial statements and should be read in conjunction with the Company’s audited financial statements
and notes thereto included in our Annual Report.
Marketable Debt Securities
Marketable debt securities
consist of debt investments with original maturities greater than three months. The Company classifies its marketable debt securities
as available-for-sale. Accordingly, these investments are recorded at fair value, which is based on quoted market prices. When
the fair value is below the amortized cost the amount of the expected credit loss is estimated. The credit-related impairment amount
is recognized in net income; the remaining impairment amount and unrealized gains are reported as a component of accumulated other
comprehensive income in stockholders’ equity. Credit losses are recognized through the use of an allowance for credit losses
account and subsequent improvements in expected credit losses are recognized as a reversal of the allowance account. If the Company
has the intent to sell the security or if it is more likely than not that the Company will be required to sell the security prior
to recovery of its amortized cost basis, the allowance for credit loss is written off and the excess of the amortized cost basis
of the asset over its fair value is recorded in net income.
Cash and Cash Equivalents
Cash and cash equivalents
are comprised of deposits at major financial banking institutions and highly liquid investments with an original maturity of three
months or less at the date of purchase. Cash equivalents are primarily invested in money market funds. The carrying amount of our
cash equivalents approximates fair value due to the short maturity of the investments. The Company regularly monitors the financial
condition of the institutions in which it has depository accounts and believes the risk of loss is minimal.
Grants Receivable
Grants receivable result
from drawdown requests to various federal agencies for reimbursement of costs incurred during the operation of the Company’s
research and development programs.
Accounts Receivable
We report accounts
receivable at net realizable value. When required we estimate losses on uncollectible accounts receivable based upon historical
data. Such allowance for doubtful accounts is estimated based upon management’s assessment of individual accounts. The Company
concluded that an allowance for doubtful accounts is not considered necessary at June 30, 2023 and December 31, 2022, as there
was no outstanding accounts receivable.
Prepaid Expenses
Our prepaid expenses consist primarily of prepaid insurance and prepaid expenses. Our insurance products
have a 12-month term and annually renew each June, with the exception of directors’ and officers’ insurance which renews
in December. Premiums are paid in advance, either annually, semi-annually, or quarterly. The collective value of any prepaid portions
of policy terms is recorded at cost. Contracts involving pre-payment are capitalized and amortized in accordance with performance.
Long-lived Assets (equipment)
Fixed assets are recorded
at cost and depreciated over their estimated useful lives.
Laboratory and office
equipment not covered by federal grant financing is depreciated on the straight-line basis over the estimated useful lives (three to ten
years). Leasehold improvements are amortized over the shorter of the lease term or estimated useful life. Long-lived assets are
evaluated for impairment when events or changes in circumstances indicate that the carrying amount of the asset or related group
of assets may not be recoverable. If the expected future undiscounted cash flows are less than the carrying amount of the asset,
an impairment loss is recognized at that time. Measurement of impairment may be based upon appraisal, market value of similar assets
or discounted cash flows.
Equipment expenditures
that are covered by federal grant financing are depreciated using the activity method (or variable charge approach) employing an
intended purpose that expires during or by the conclusion of the funded project. Such equipment acquisition expenditures are therefore
effectively expensed if the timing of the intended purpose is within the same reporting period as delivery.
At June 30, 2023 and
December 31, 2022, the Company’s long-lived assets of $125,859 have been fully depreciated.
Accounts Payable
Accounts payable are
short term liabilities with product/service vendors, including any credit card liability.
Accrued Expenses
Accrued expenses are
recorded when incurred but have not been paid by period end. See Note 6 related to the balance at June 30, 2023 and December 31,
2022.
Revenue Recognition
On January 1, 2018,
the Company adopted ASU No. 2014-09, Revenue from Contracts with Customers (“Topic 606”), to account for revenue. The
deliverables under our arrangements are evaluated under Topic 606, which requires an entity to recognize revenue in a manner that
depicts the transfer of promised goods or services to customers in an amount that reflects the consideration to which the entity
expects to be entitled in exchange for those goods or services.
The Company recognizes
revenue when persuasive evidence of an arrangement exists, delivery occurs, the fee was fixed or determinable, and collectability
is reasonably assured.
The Company’s
contract revenue consists primarily of amounts earned under contracts with third-party customers and reimbursed expenses under
such contracts. The Company analyzes its agreements to determine whether the elements can be separated and accounted for individually
or as a single unit of accounting. Allocation of revenue to individual elements that qualify for separate accounting is based on
the separate selling prices determined for each component, and total contract consideration is then allocated pro rata across the
components of the arrangement.
In general, the Company
applies the following steps when recognizing revenue from contracts with customers: (i) identify the contract, (ii) identify the
performance obligations, (iii) determine the transaction price, (iv) allocate the transaction price to the performance obligations
and (v) recognize revenue when a performance obligation is satisfied.
Recognition of revenue
is driven by satisfaction of the performance obligations using one of two methods: revenue is either recognized over time or at
a point in time. Revenue is generally recognized as the performance obligations are satisfied, which generally occurs when control
of the goods or services have been transferred to the customer or once the customer is able to use those goods and/or services
as well as obtaining substantially all of their benefits.
The Company primarily
generates contract revenue under fixed-fee contracts or time and materials contracts:
|
● |
Under a fixed-fee contract, the Company charges a fixed agreed upon amount for a deliverable. Fixed-fee contracts have fixed deliverables upon completion of the project. Typically, the Company recognizes revenue for fixed-fee contracts after projects are completed, delivery is made and title transfers to the customer, and collection is reasonably assured. |
|
● |
Under a time and materials contract, the Company charges customers an
hourly rate plus reimbursement for other project specific costs. The Company recognizes revenue for time and material contracts
based on the number of hours devoted to the project multiplied by the customer’s billing rate plus other project specific
costs. Payment terms vary, but are generally due within 60 days. |
Grant Revenues
The Company receives
revenue through government grants, primarily with the National Institutes of Health (“NIH”). The Company has concluded
its government grants are not within the scope of Topic 606, as government entities do not meet the definition of a “customer”
as defined by Topic 606 because there is not considered to be a transfer of control of goods or services to the government entity
funding the grant. Grant revenue, which is not within the scope of Topic 606, consists of funding under cost reimbursement programs
primarily from federal and non-profit foundation sources for qualified research and development activities performed by us, and
as such, are not based on estimates that are susceptible to change. Such amounts are invoiced and recorded as revenue as grant-funded
activities are performed, with any advance funding recorded as deferred revenue until the activities are performed. The Company
believes the recognition of revenue as costs are incurred and amounts become earned/realizable is analogous to the concept of transfer
of control of a service over time under Topic 606.
Lease Obligations
The Company determines
if an agreement is a lease at inception. The Company evaluates the lease terms to determine whether the lease will be accounted
for as an operating or finance lease. Operating leases are included in operating lease right-of-use (“ROU”) assets,
operating lease liabilities, current portion, and operating lease liabilities, net of current portion in our consolidated balance
sheets.
ROU assets represent
our right to use an underlying asset for the lease term, and lease liabilities represent our obligation to make lease payments
arising from the lease. Operating lease ROU assets and liabilities are recognized at commencement date based on the present value
of lease payments over the lease term. As most of our leases do not provide an implicit rate, we use our incremental borrowing
rate based on the information available at commencement date in determining the present value of lease payments. The Company uses
the implicit rate when readily determinable. The operating lease ROU asset also includes any lease payments made and excludes lease
incentives. Our lease terms may include options to extend or terminate the lease when it is reasonably certain that we will exercise
that option. Lease expense for lease payments is recognized on a straight-line basis over the lease term.
A lease that transfers
substantially all of the benefits and risks incidental to ownership of property are accounted for as finance leases. At the inception
of a finance lease, an asset and finance lease obligation is recorded at an amount equal to the lesser of the present value of
the minimum lease payments and the property’s fair market value. Finance lease obligations are classified as either current
or long-term based on the due dates of future minimum lease payments, net of interest. At June 30, 2023 and December 31, 2022,
there were no finance leases.
Research and Development
The Company accounts
for research and development costs in accordance with ASC 730-10, Research and Development (“ASC 730-10”).
Under ASC 730-10, all research and development costs must be charged to expense as incurred. Accordingly, internal research and
development costs are expensed as incurred. Third-party research and development costs are expensed when the contracted work has
been performed or as milestone results have been achieved. Research and development expenses include salaries and benefits, facilities
and other overhead expense, external clinical trial expenses, research related manufacturing services, contract services and other
outside expenses.
Patent Costs and Rights
Costs of applying for,
prosecuting and maintaining patents and patent rights are expensed as incurred due to uncertainty of future economic benefit.
Clinical Trial Costs
Clinical trial costs
are charged to us and recognized as the tasks are completed by the contractor(s) or, alternatively, may be invoiced in accordance
with agreed-upon payment schedules and recognized based on estimates of work completed to date.
Stock Option Compensation Expense
The Company recognizes the fair value of stock option award expenses on a straight-line basis over a service
period of three years, consistent with vesting periods, using the Black-Scholes options pricing model to estimate the fair value
of option awards. Such expenses are categorized as research and development or general and administrative depending on the role
of each option recipient.
The Company recognizes
the income tax benefits and deficiencies as income tax expense or benefit in the statement of operations and the tax effects of
exercised or vested awards are treated as discrete items in the reporting period in which they occur. The Company also recognizes
excess tax benefits regardless of whether the benefit reduces taxes payable in the current period. Excess tax benefits are classified
along with other income tax cash flows as an operating activity in the statement of cash flows. Regarding forfeitures, the Company
accounts for them when they occur. See Note 9 for more information on our stock options.
Warrants
The Company accounts
for Common Stock warrants as either liabilities or as equity instruments depending on the specific terms of the warrant agreements.
Generally, warrants are classified as liabilities, as opposed to equity, if the agreement includes the potential for a cash settlement
or an adjustment to the exercise price, and warrant liabilities are recorded at their fair values at each balance sheet date. See
Note 12 related to issued warrants.
Income Taxes
The Company accounts
for income taxes in accordance with the asset and liability method of accounting for income taxes prescribed by FASB ASC Topic
740, “Accounting for Income Taxes” (“ASC 740”). Under the asset and liability method of ASC 740,
deferred tax assets and liabilities are recognized for the future tax consequences attributable to differences between the financial
statement carrying amounts of existing assets and liabilities and their respective tax basis and operating loss and tax credit
carry-forwards. Deferred tax assets and liabilities are measured using enacted tax rates expected to apply to the taxable income
in the years in which those temporary differences are expected to be recovered or settled. Under ASC 740, the effect on deferred
tax assets and liabilities of a change in tax rates is recognized in income in the period that includes the enactment dates. The
Company evaluates its deferred income taxes to determine if a valuation allowance should be established against the deferred tax
assets or if the valuation allowance should be reduced based on consideration of all available evidence, both positive and negative,
using a “more likely than not” standard.
The Company follows
FASB ASC Topic 740-10, “Accounting for Uncertainty in Income Taxes” (“Topic 740-10”), which prescribes
a recognition threshold and measurement attribute for financial statement recognition and measurement of a tax position taken,
or expected to be taken, in a tax return. For those benefits to be recognized, a tax position must be more likely than not to be
sustained upon examination by taxing authorities. At June 30, 2023 and December 31, 2022, the Company had no material uncertain
tax positions to be accounted for in the financial statements. The Company recognizes interest and penalties, if any, related to
unrecognized tax benefits in interest expense. See Note 14 related to income taxes.
Concentration of Credit Risk
The
Company’s grant revenues and grant receivables were with the NIH. The NIH is an agency of the United States Department of
Health & Human Services, and the Company believes amounts are fully collectible from this agency. Contract revenues were $224,724
for the six months ended June 30, 2023, and $106,676 for the three months ended June 30, 2023.
Earnings Per Share
Basic
net loss per share of Common Stock is computed by dividing the net loss for the period by the weighted-average number of
shares of Common Stock outstanding during the period. Diluted net loss per common share is computed giving effect to all dilutive
Common Stock equivalents, consisting of stock options and warrants. Diluted net loss per share of Common Stock for the six months
ended June 30, 2023 and 2022 is the same as basic net loss per share, as the Common Stock equivalents were anti-dilutive due to
the net loss.
Due to the Stock Split, the shares outstanding
at June 30, 2022 have been retroactively adjusted, reducing them from 9,666,562 to 3,866,625. This had a corresponding increase
in the loss per share of Common Stock from $0.16 to $0.39 per share for the six months ended June 30, 2022, and from $0.08 to $0.20
per share for the three months ended June 30, 2022.
At June 30, 2023 and 2022, the Common Stock equivalent shares
were, as follows:
Schedule of common stock equivalent shares
| |
|
|
|
|
|
| |
| |
June
30, | |
| |
2023 | | |
2022 | |
Shares
of Common Stock issuable under equity incentive plans outstanding | |
| 2,478,000 | | |
| 2,054,000 | |
Shares of Common Stock
issuable upon exercise of warrants
| |
| 143,994 | | |
| 143,994 | |
Shares
of Common Stock issuable upon conversion of Series A Preferred Stock | |
| — | | |
| 636,979 | |
Common
Stock equivalent shares excluded from diluted net loss per share | |
| 2,621,994 | | |
| 2,834,973 | |
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v3.23.2
Fair Value Measurements and Marketable Debt Securities
|
6 Months Ended |
Jun. 30, 2023 |
Fair Value Disclosures [Abstract] |
|
Fair Value Measurements and Marketable Debt Securities |
Note 4. Fair Value Measurements and Marketable Debt Securities
In accordance with
ASC 820, “Fair Value Measurements and Disclosures” (“ASC 820”), the Company measure its assets and
liabilities at fair value. We apply the three-level valuation hierarchy as described in ASC 820, which is based upon the transparency
of input as of the measurement date. The three levels of inputs as defined are:
Level 1 - Inputs to the
valuation methodology are quoted prices (unadjusted) for identical assets or liabilities in active markets.
Level 2 - Inputs to the
valuation methodology include quoted prices for similar assets and liabilities in active markets, and inputs that are observable
for the asset or liability, either directly or indirectly, for substantially the full term of the financial instruments.
Level 3 - Inputs to the
valuation methodology are unobservable and significant to the fair value measurement.
At June 30, 2023 and
December 31, 2022, the Company’s financial instruments consist primarily of: cash and cash equivalents, accounts payable
and accrued liabilities. For cash equivalents, accounts payable and accrued liabilities, the carrying amounts of these financial
instruments as of June 30, 2023 and December 31, 2022 were considered representative of their fair values due to their short term
to maturity.
The Company held no
marketable securities or cash equivalents at December 31, 2022, and no marketable securities at June 30, 2023. For cash equivalents
at June 30, 2023 the fair value input levels are summarized below:
June 30, 2023 | |
Level 1 | | |
Level 2 | | |
Level 3 | | |
Total | |
Cash Equivalents (maturity less than 90 days) | |
| | | |
| | | |
| | | |
| | |
Commercial Paper | |
$ | — | | |
| — | | |
| — | | |
$ | — | |
U.S. Government | |
| — | | |
| — | | |
| — | | |
| — | |
Money market funds | |
| 2,801,063 | | |
| — | | |
| — | | |
| 2,801,063 | |
Total Cash equivalents | |
| 2,801,063 | | |
| | | |
| | | |
| 2,801,063 | |
| |
| | | |
| | | |
| | | |
| | |
Marketable Securities | |
| — | | |
| — | | |
| — | | |
| — | |
Total Cash Equivalents and Marketable Securities | |
$ | 2,801,063 | | |
$ | — | | |
$ | — | | |
$ | 2,801,063 | |
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v3.23.2
Prepaid Expenses
|
6 Months Ended |
Jun. 30, 2023 |
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Abstract] |
|
Prepaid Expenses |
Note 5. Prepaid Expenses
At June 30, 2023, prepaid
expenses consisted primarily of prepaid insurance of $194,384 and $30,918 in prepaid expenses. At December 31, 2022, prepaid expenses
consisted of $433,891 of prepaid insurance, and $130,000 of prepaid investor relations and advisory services.
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v3.23.2
Accrued Expenses
|
6 Months Ended |
Jun. 30, 2023 |
Payables and Accruals [Abstract] |
|
Accrued Expenses |
Note 6. Accrued Expenses
At June 30, 2023 accrued
expenses were $138,704, resulting from unbilled clinical expenses of $28,675 and $110,029 of unbilled professional services expenses.
At December 31, 2022, the $389,209 of accrued expenses consisted of $224,871 in accrued professional expenses, and $164,338 in
accrued clinical expenses.
|
X |
- DefinitionThe entire disclosure for accounts payable and accrued liabilities at the end of the reporting period.
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v3.23.2
Notes Payable – Related Party
|
6 Months Ended |
Jun. 30, 2023 |
Debt Disclosure [Abstract] |
|
Notes Payable – Related Party |
Note 7. Notes Payable – Related Party
At December 31, 2022,
there was a $250,000 note outstanding, payable to Dr. Jonathan Kaufman, the Company’s Chief Executive Officer. The note payable
was due within one year and was issued by the Company in exchange for cash contributions made by Dr. Kaufman to the Company. The
note and accrued interest were paid in full as of June 30, 2023.
The note obligation and accrued interest are provided in the following table.
Origination | | |
Original Principal | | |
Current Principal | | |
Rate | | |
Maturity | | |
Accrued Interest - Related Party December 31, 2022 | | |
Accrued Interest - Related Party March 31, 2023 | | |
Accrued Interest - Related Party June 30, 2023 | | |
Category | |
November 1, 2022 | | |
$ | 250,000 | | |
$ | - | | |
| 8.75 | % | |
| 06/30/23 | | |
$ | 3,596 | | |
$ | 8,990 | | |
$ | — | | |
| Current | |
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v3.23.2
Letter of Credit
|
6 Months Ended |
Jun. 30, 2023 |
Letter Of Credit |
|
Letter of Credit |
Note 8. Letter of Credit
The Company has a letter
of credit with a bank for an aggregate available borrowing of $50,000 due upon demand. The letter of credit is collateralized by
substantially all of the Company’s assets and personally guaranteed by Dr. Jonathan Kaufman, the Company’s Chief Executive
Officer. The outstanding advances under the line of credit bear interest at the lending bank’s prime rate plus 3.10%. In
February 2023, the Company repaid all amounts outstanding under the letter of credit. The outstanding balance was $0 and $25,000
at June 30, 2023 and December 31, 2022, respectively.
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v3.23.2
Stock Options
|
6 Months Ended |
Jun. 30, 2023 |
Share-Based Payment Arrangement [Abstract] |
|
Stock Options |
Note 9. Stock Options
The
Company previously had two incentive plans in effect pursuant to which incentive stock options and nonqualified stock options
were issued. The maximum number of shares Common Stock that may be issued upon exercise of such outstanding options as of June
30, 2023 was 2,478,000 shares. This number comprises 1,078,000 unexpired options issued and outstanding granted under the
Company’s expired 2008 Stock Incentive Plan and 1,400,000 options issued and outstanding granted under the Company’s
Amended and Restated Stock Incentive Plan, which was originally adopted in 2020 and amended and restated in 2022 (the “2020
Plan”), which is the only Company incentive plan currently in effect. Incentive stock options granted under the 2020 Plan
are granted with an exercise price determined by the Company’s board of directors (the “Board”) or the Board’s compensation committee (the “Compensation Committee”).
Unless otherwise provided for by the Board or the Compensation Committee, vesting of options granted under the 2020 Plan terminates once the
optionee is no longer affiliated with the Company, subject to certain exceptions. Such options generally expire ten years from
the date of the grant (five years in the case of incentive stock options granted to holders of over 10% of Common Stock). Stock
options are granted under the 2020 Plan with an exercise price not less than the fair market value of the underlying Common Stock
on the date of the grant and incentive stock options granted to holders of over 10% of Common Stock are granted with an exercise
price not less than 110% of such fair market value on such grant date. Unless otherwise specified by the Board or the Compensation Committee,
all grants under the 2020 Plan vest fully over a three-year period, provided that the employee continues to be employed, subject
to certain exceptions. If an employee leaves the Company prior to the full vesting of such option awards, then the remaining unvested
portion is considered forfeited, and the earlier recognition of the unvested shares is reversed during the period of forfeiture.
As of June 30, 2023 and December 31, 2022 there was $806,157 and $1,222,500, respectively, of unrecognized compensation costs
related to non-vested share-based compensation arrangements granted to be recognized over the weighted average period of approximately
18 months.
The Company recognized
$847,618 and $213,489 of compensation costs related to stock option vesting for the three months ended June 30, 2023 and 2022,
respectively. The Company recognized $1,056,257 and $448,637 of compensation costs related to stock option vesting for the six
months ended June 30, 2023 and 2022, respectively.
The following is an analysis of options to purchase shares of Common Stock issued and outstanding as of
June 30, 2023 and December 31, 2022:
| |
Shares | | |
Weighted- Average Exercise Price Per Share ($) | | |
Weighted- Average Remaining Contractual Term (in Years) | | |
Aggregate intrinsic value ($) | |
Outstanding as of December 31, 2021 | |
| 2,044,000 | | |
| 2.82 | | |
| 6.61 | | |
| 4,446,667 | |
Granted | |
| 10,0000 | | |
| 5.00 | | |
| 9.16 | | |
| | |
Expired | |
| — | | |
| | | |
| | | |
| | |
Cancelled | |
| — | | |
| | | |
| | | |
| | |
Exercised | |
| — | | |
| | | |
| | | |
| | |
Outstanding as of December 31, 2022 | |
| 2,054,000 | | |
| 2.84 | | |
| 5.51 | | |
| 605,687 | |
Granted | |
| — | | |
| | | |
| | | |
| | |
Expired | |
| — | | |
| | | |
| | | |
| | |
Cancelled | |
| — | | |
| | | |
| | | |
| | |
Exercised | |
| — | | |
| | | |
| | | |
| | |
Outstanding as of March 31, 2023 | |
| 2,054,000 | | |
| 2.84 | | |
| 5.26 | | |
$ | — | |
Granted | |
| 424,000 | | |
| 2.19 | | |
| 9.96 | | |
| | |
Expired | |
| — | | |
| | | |
| | | |
| | |
Cancelled | |
| — | | |
| | | |
| | | |
| | |
Exercised | |
| — | | |
| | | |
| | | |
| | |
Outstanding as of June 30, 2023 | |
| 2,478,000 | | |
| 2.72 | | |
| 5.86 | | |
$ | — | |
Vested as of June 30, 2023 | |
| 2,190,667 | | |
| | | |
| | | |
| | |
Exercisable as of June 30, 2023 | |
| 2,190,667 | | |
| | | |
| | | |
| | |
Exercisable as of December 31, 2022 | |
| 1,619,333 | | |
| | | |
| | | |
| | |
A
summary of status of the Company’s non-vested stock options (exercisable for shares of Common Stock on a one-to-one basis)
as of, and changes during, the six months ended June 30, 2023 and 2022 is presented below:
| |
Number of Stock Options | | |
Weighted- Average Fair Value Grant Date | |
Nonvested at December 31, 2021 | |
| 688,667 | | |
$ | 2.82 | |
Granted | |
| 10,000 | | |
$ | 2.84 | |
Vested | |
| (157,333 | ) | |
$ | 2.83 | |
Expired | |
| — | | |
$ | 0.00 | |
Nonvested at June 30, 2022 | |
| 541,333 | | |
$ | 2.82 | |
| |
| | | |
| | |
Nonvested at December 31, 2022 | |
| 434,667 | | |
$ | 2.82 | |
Granted | |
| 424,000 | | |
| 2.19 | |
Vested | |
| (423,334 | ) | |
| 2.83 | |
Expired | |
| — | | |
| — | |
Nonvested at June 30, 2023 | |
| 435,333 | | |
$ | 2.81 | |
In
the six months ended June 30, 2023 and 2022, the Company granted options as presented below.
Stock
Option Grants - On March 1, 2022, the Company issued 10,000 stock options at a $5.00 strike price, vesting immediately upon
issuance.
On
June 16, 2023, the Company issued 424,000 stock options at a $2.19 strike price, vesting immediately upon issuance.
The
weighted-average fair value of stock options on the date of grant and the assumptions used to estimate the fair value of stock
options granted during the six months ended June 30, 2023 and June 30, 2022 using the Black-Scholes option-pricing model is as
follows:
Six months ended June 30: | |
2023 | | |
2022 | |
Weighted-average fair value of options granted | |
$ | 1.50 | | |
| 1.14 | |
Expected volatility | |
| 83.47 | % | |
| 75 | % |
Expected life (in years) | |
| 5.04 | | |
| 10 | |
Risk-free interest rate (range) | |
| 3.99 | % | |
| 2.31 | % |
Expected dividend yield | |
$ | — | | |
| — | |
|
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v3.23.2
Preferred Stock
|
6 Months Ended |
Jun. 30, 2023 |
Equity [Abstract] |
|
Preferred Stock |
Note
10. Preferred Stock
The
Company’s Second Amended and Restated Certificate of Incorporation (the “Charter”) authorizes the issuance
of 20,000,000 shares of preferred stock, par value $0.0001 per share. The Company’s Certificate of Designation of Preferences,
Rights and Limitations of Series A Preferred Stock sets forth the rights of the Series
A Preferred Stock, par value $0.0001 per share, of the Company (the “Series A Stock”) and authorizes the issuance
of up to 5,000,000 shares of Series A Stock. With respect to dividend rights and rights in the event of the liquidation or dissolution
of the Company, the Series A Stock ranks prior to all Common Stock and any other series of preferred stock which is junior to
Series A Stock. Upon any matter submitted to the shareholders of the Company for a vote, each holder of Series A Stock is entitled
to the number of votes as is equal to the number of shares of Common Stock into which such shares of Series A Stock are convertible
at the time of such vote. The Series A Stock is not entitled to any mandatory dividends.
The
Series A Stock is convertible into Common Stock on a one-to-one basis. In the event of the liquidation or dissolution of the Company,
the holders of the Series A Stock are entitled to receive the greater of $0.60 per share, representing a liquidation preference
of $0 as of June 30, 2023 and December 31, 2022. The Series A Stock is not entitled to dividends, and is not considered “participating”
preferred, meaning converted securities are not entitled to a liquidation preference, and if a liquidation preference has been
taken, the associated security interest is dissolved. Prior to the completion of our initial public offering, all of the Series
A Stock would have automatically converted into Common Stock upon any one of the following three conditions: a public offering
of at least $7,000,000 of gross proceeds, the optional conversion of at least 80% of issued shares of Series A Stock, or the consent
of holders of a majority of the Series A Stock. The shares of Series A Stock have average-weighted anti-dilution protection that
becomes effective upon the issuance of Common Stock (or securities convertible into Common Stock) at a price below $0.60 per share.
If
upon a liquidation event the assets of the Company available for distribution are insufficient to pay the holders of the Series
A Stock the full amount as to which they are entitled, then the entire amount available will be distributed among the holders
of the Series A Stock ratably in accordance with the respective amounts that would have been payable on such shares of Series
A Stock if the amounts were paid in full. If after the Series A Stock holders have been paid in full, the Common Stock shall be
entitled to receive any and all assets remaining to be paid or distributed.
In
the year ended December 31, 2022, all 1,592,447 outstanding shares of Series A Stock were converted to Common Stock on a 1:1 basis.
After the effect of the Stock Split, this conversion resulted in 636,979 shares of Common Stock. There were no shares of Series
A Stock outstanding at December 31, 2022 or June 30, 2023.
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v3.23.2
Common Stock
|
6 Months Ended |
Jun. 30, 2023 |
Equity [Abstract] |
|
Common Stock |
Note
11. Common Stock
The
Charter authorizes the issuance of 200,000,000 shares of Common Stock. On December 19, 2022, the Company effected the Stock Split,
with a 2.5 to 1 share conversion ratio for all shares of Common Stock outstanding. The Company’s outstanding share and per
share amounts in these unaudited condensed financial statements have been adjusted to give effect to the Stock Split, for all periods presented. There
were 5,743,945 shares of Common Stock outstanding as of June 30, 2023 and December 31, 2022.
During
the year ended December 31, 2022, the Company issued 22,950 shares of Common Stock in forgiveness of two related party notes.
The aggregate principal and interest of the notes was $138,810. On December 22, 2022, we completed an initial public offering
(“IPO”) and listing on the Nasdaq Capital Market (“Nasdaq”) of our Common Stock at a price to the public
of $5.75 per share, which resulted in the issuance of an additional 1,217,391 shares of Common Stock. The aggregate net proceeds
from the IPO were approximately $5,000,000 after deducting underwriting discounts and commissions of $630,000 and offering expenses
of approximately $1,160,000.
The
Common Stock is subject to and qualified by the rights of the Series A Stock. Upon the dissolution or liquidation of the Company
the holders of Common Stock will be entitled to receive all assets of the Company available for distribution to its stockholders,
subject to any preferential rights of any then outstanding Series A Stock.
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v3.23.2
Warrants
|
6 Months Ended |
Jun. 30, 2023 |
Warrants |
|
Warrants |
Note
12. Warrants
No
warrants were issued in the six months ended June 30, 2023, or the year ended December 31, 2022. In the year ended December 31,
2021, in connection with the issuance of shares of Common Stock, 143,994 warrants exercisable into an equal number of shares of
Common Stock were issued. The warrants have a 5-year term and an exercise price of $5.00 per share (after giving effect to the
Stock Split). The Company had no warrant liabilities at June 30, 2023 or December 31, 2022.
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v3.23.2
Commitment and Contingencies
|
6 Months Ended |
Jun. 30, 2023 |
Commitments and Contingencies Disclosure [Abstract] |
|
Commitment and Contingencies |
Note
13. Commitment and Contingencies
Operating
Leases
Operating
leases are recorded as ROU assets and lease liabilities on the balance sheet. ROU assets represent our right to use the leased
asset for the lease term and lease liabilities represent our obligation to make lease payments. Operating lease ROU assets and
liabilities are recognized at commencement date based on the present value of lease payments over the lease term. As most of the
Company’s leases do not provide an implicit rate, the Company uses its estimated incremental borrowing rate at the commencement
date to determine the present value of lease payments. The operating lease ROU assets also include any lease payments made and
exclude lease incentives.
The
Company entered into a lease agreement beginning July 1, 2020, for the Company’s principal headquarters at 7800 Susquehanna
Street, Pittsburgh, Pennsylvania, which includes office space and sterile manufacturing operations (the “Lease”).
The Lease has a five-year term and includes an option for renewal, which is not reasonably certain and is excluded from the right
of use calculation. Future minimum rent payments under the Lease as of June 30, 2023 are as follows:
Year ending | |
| |
2023 (6 months remaining) | |
$ | 33,476 | |
2024 | |
$ | 67,289 | |
2025 | |
$ | 33,813 | |
Total minimum lease payments | |
$ | 134,578 | |
Less: amount representing interest | |
$ | (8,400 | ) |
Present value of minimum lease payments | |
$ | 126,178 | |
The
Lease is accounted for as a ROU and liability. As of June 30, 2023, the Company has $122,547 of an operating lease ROU asset,
and $60,788 and $65,390 of current and non-current lease liabilities, respectively, recorded on the balance sheets. As of December
31, 2022 the Company had an ROU asset of $150,821, and current and non-current operating lease liabilities of $58,262 and $96,258
respectively. The lease expense for the three months ended June 30, 2023 and June 30, 2022 was $16,436 and $16,245, respectively.
The lease expense for the six months ended June 30, 2023 and June 30, 2022 was $32,737 and $32,602, respectively. Cash paid for
the amounts included in the measurement of lease liabilities for the three months ended June 30, 2023 and June 30, 2022 was $16,402
and $16,066, respectively, and for the six months ended June 30, 2023 and 2022 was $32,804 and $32,131 respectively. The payments
are included in the operating activities in the accompanying statement of cash flows.
Contract
Commitments
The
Company enters into contracts in the normal course of business with contract research organizations (“CROs”), contract
manufacturing organizations (“CMOs”), universities, and other third parties for preclinical research studies, clinical
trials and testing and manufacturing services. These contracts generally do not contain minimum purchase commitments and are cancelable
by us upon prior written notice although, purchase orders for clinical materials are generally non-cancelable. Payments due upon
cancellation consist only of payments for services provided or expenses incurred, including non-cancelable obligations of our
service providers, up to the date of cancellation or upon the completion of a manufacturing run.
Partnering
Commitments
In
February 2022, the Company entered into an agreement whereby it partnered with an advisor to assist with potential transactions.
The Company paid $10,000 per month for the first four months of the agreement’s term. The agreement (which was terminated
in June 2022), included a surviving success fee, such that in the event of a successful transaction occurring prior to September
2023, required the Company to make a payment equal to the greater of (a) five percent of the transaction value and (b) $500,000.
For the three months ended June 30, 2023, and June 30, 2022, the Company has recorded $0 and $30,000, respectively, in general
and administrative expense related to this commitment, and has not recorded any additional liabilities related to the surviving
success fee clause as of the balance sheet date.
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v3.23.2
Income Taxes
|
6 Months Ended |
Jun. 30, 2023 |
Income Tax Disclosure [Abstract] |
|
Income Taxes |
Note
14. Income Taxes
The
provision for income taxes for the three and six months ended June 30, 2023 and 2022 was $0, resulting in an effective income
tax rate of 0% for each period. The Company’s effective tax rate for the three and six months ended June 30, 2023 and 2022
is primarily due to the full valuation allowance against the Company’s net deferred tax assets.
The
Company regularly evaluates the realizability of its deferred tax assets and establishes a valuation allowance if it is more likely
than not that some or all of the deferred tax assets will not be utilized. Because of our cumulative losses, substantially all
of the deferred tax assets have been fully offset by a valuation allowance as of June 30, 2023 and December 31, 2022. We have
not paid income taxes for the year ended December 31, 2022.
The
Company’s 2018 through 2022 tax years remain subject to examination by the Internal Revenue Service for federal tax purposes
and the State of Pennsylvania for state tax purposes.
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v3.23.2
Subsequent Events
|
6 Months Ended |
Jun. 30, 2023 |
Subsequent Events [Abstract] |
|
Subsequent Events |
Note
15. Subsequent Events
Subsequent
events have been evaluated through the date of the independent auditors’ report , which is the date the unaudited condensed financial statements
were available to be issued.
Effective August 1, 2023, the Company became party to a lease for additional space at their current
location (the “August 2023 Lease”). The August 2023 Lease will co-terminate with the Lease on June 30, 2025, with an option to extend for five years. Under
the August 2023 Lease, the Company expects to pay an additional $11,483 in rent during the calendar year 2023.
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- DefinitionThe entire disclosure for significant events or transactions that occurred after the balance sheet date through the date the financial statements were issued or the date the financial statements were available to be issued. Examples include: the sale of a capital stock issue, purchase of a business, settlement of litigation, catastrophic loss, significant foreign exchange rate changes, loans to insiders or affiliates, and transactions not in the ordinary course of business.
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v3.23.2
Summary of Significant Accounting Policies (Policies)
|
6 Months Ended |
Jun. 30, 2023 |
Accounting Policies [Abstract] |
|
Use of Estimates |
Use of Estimates
The preparation of
financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the reported amounts
of assets and liabilities and disclosure of contingent assets and liabilities at the date of these financial statements. Actual
results could differ from those estimates.
|
Basis of Presentation |
Basis of Presentation
The unaudited condensed
financial statements have been prepared in accordance with GAAP for interim financial information and Article 10 of Regulation
S-X. Accordingly, the unaudited condensed financial statements do not include all of the information and footnotes required by
GAAP for complete financial statements and should be read in conjunction with the Company’s audited financial statements
and notes thereto included in our Annual Report.
|
Marketable Debt Securities |
Marketable Debt Securities
Marketable debt securities
consist of debt investments with original maturities greater than three months. The Company classifies its marketable debt securities
as available-for-sale. Accordingly, these investments are recorded at fair value, which is based on quoted market prices. When
the fair value is below the amortized cost the amount of the expected credit loss is estimated. The credit-related impairment amount
is recognized in net income; the remaining impairment amount and unrealized gains are reported as a component of accumulated other
comprehensive income in stockholders’ equity. Credit losses are recognized through the use of an allowance for credit losses
account and subsequent improvements in expected credit losses are recognized as a reversal of the allowance account. If the Company
has the intent to sell the security or if it is more likely than not that the Company will be required to sell the security prior
to recovery of its amortized cost basis, the allowance for credit loss is written off and the excess of the amortized cost basis
of the asset over its fair value is recorded in net income.
|
Cash and Cash Equivalents |
Cash and Cash Equivalents
Cash and cash equivalents
are comprised of deposits at major financial banking institutions and highly liquid investments with an original maturity of three
months or less at the date of purchase. Cash equivalents are primarily invested in money market funds. The carrying amount of our
cash equivalents approximates fair value due to the short maturity of the investments. The Company regularly monitors the financial
condition of the institutions in which it has depository accounts and believes the risk of loss is minimal.
|
Grants Receivable |
Grants Receivable
Grants receivable result
from drawdown requests to various federal agencies for reimbursement of costs incurred during the operation of the Company’s
research and development programs.
|
Accounts Receivable |
Accounts Receivable
We report accounts
receivable at net realizable value. When required we estimate losses on uncollectible accounts receivable based upon historical
data. Such allowance for doubtful accounts is estimated based upon management’s assessment of individual accounts. The Company
concluded that an allowance for doubtful accounts is not considered necessary at June 30, 2023 and December 31, 2022, as there
was no outstanding accounts receivable.
|
Prepaid Expenses |
Prepaid Expenses
Our prepaid expenses consist primarily of prepaid insurance and prepaid expenses. Our insurance products
have a 12-month term and annually renew each June, with the exception of directors’ and officers’ insurance which renews
in December. Premiums are paid in advance, either annually, semi-annually, or quarterly. The collective value of any prepaid portions
of policy terms is recorded at cost. Contracts involving pre-payment are capitalized and amortized in accordance with performance.
|
Long-lived Assets (equipment) |
Long-lived Assets (equipment)
Fixed assets are recorded
at cost and depreciated over their estimated useful lives.
Laboratory and office
equipment not covered by federal grant financing is depreciated on the straight-line basis over the estimated useful lives (three to ten
years). Leasehold improvements are amortized over the shorter of the lease term or estimated useful life. Long-lived assets are
evaluated for impairment when events or changes in circumstances indicate that the carrying amount of the asset or related group
of assets may not be recoverable. If the expected future undiscounted cash flows are less than the carrying amount of the asset,
an impairment loss is recognized at that time. Measurement of impairment may be based upon appraisal, market value of similar assets
or discounted cash flows.
Equipment expenditures
that are covered by federal grant financing are depreciated using the activity method (or variable charge approach) employing an
intended purpose that expires during or by the conclusion of the funded project. Such equipment acquisition expenditures are therefore
effectively expensed if the timing of the intended purpose is within the same reporting period as delivery.
At June 30, 2023 and
December 31, 2022, the Company’s long-lived assets of $125,859 have been fully depreciated.
|
Accounts Payable |
Accounts Payable
Accounts payable are
short term liabilities with product/service vendors, including any credit card liability.
|
Accrued Expenses |
Accrued Expenses
Accrued expenses are
recorded when incurred but have not been paid by period end. See Note 6 related to the balance at June 30, 2023 and December 31,
2022.
|
Revenue Recognition |
Revenue Recognition
On January 1, 2018,
the Company adopted ASU No. 2014-09, Revenue from Contracts with Customers (“Topic 606”), to account for revenue. The
deliverables under our arrangements are evaluated under Topic 606, which requires an entity to recognize revenue in a manner that
depicts the transfer of promised goods or services to customers in an amount that reflects the consideration to which the entity
expects to be entitled in exchange for those goods or services.
The Company recognizes
revenue when persuasive evidence of an arrangement exists, delivery occurs, the fee was fixed or determinable, and collectability
is reasonably assured.
The Company’s
contract revenue consists primarily of amounts earned under contracts with third-party customers and reimbursed expenses under
such contracts. The Company analyzes its agreements to determine whether the elements can be separated and accounted for individually
or as a single unit of accounting. Allocation of revenue to individual elements that qualify for separate accounting is based on
the separate selling prices determined for each component, and total contract consideration is then allocated pro rata across the
components of the arrangement.
In general, the Company
applies the following steps when recognizing revenue from contracts with customers: (i) identify the contract, (ii) identify the
performance obligations, (iii) determine the transaction price, (iv) allocate the transaction price to the performance obligations
and (v) recognize revenue when a performance obligation is satisfied.
Recognition of revenue
is driven by satisfaction of the performance obligations using one of two methods: revenue is either recognized over time or at
a point in time. Revenue is generally recognized as the performance obligations are satisfied, which generally occurs when control
of the goods or services have been transferred to the customer or once the customer is able to use those goods and/or services
as well as obtaining substantially all of their benefits.
The Company primarily
generates contract revenue under fixed-fee contracts or time and materials contracts:
|
● |
Under a fixed-fee contract, the Company charges a fixed agreed upon amount for a deliverable. Fixed-fee contracts have fixed deliverables upon completion of the project. Typically, the Company recognizes revenue for fixed-fee contracts after projects are completed, delivery is made and title transfers to the customer, and collection is reasonably assured. |
|
● |
Under a time and materials contract, the Company charges customers an
hourly rate plus reimbursement for other project specific costs. The Company recognizes revenue for time and material contracts
based on the number of hours devoted to the project multiplied by the customer’s billing rate plus other project specific
costs. Payment terms vary, but are generally due within 60 days. |
|
Grant Revenues |
Grant Revenues
The Company receives
revenue through government grants, primarily with the National Institutes of Health (“NIH”). The Company has concluded
its government grants are not within the scope of Topic 606, as government entities do not meet the definition of a “customer”
as defined by Topic 606 because there is not considered to be a transfer of control of goods or services to the government entity
funding the grant. Grant revenue, which is not within the scope of Topic 606, consists of funding under cost reimbursement programs
primarily from federal and non-profit foundation sources for qualified research and development activities performed by us, and
as such, are not based on estimates that are susceptible to change. Such amounts are invoiced and recorded as revenue as grant-funded
activities are performed, with any advance funding recorded as deferred revenue until the activities are performed. The Company
believes the recognition of revenue as costs are incurred and amounts become earned/realizable is analogous to the concept of transfer
of control of a service over time under Topic 606.
|
Lease Obligations |
Lease Obligations
The Company determines
if an agreement is a lease at inception. The Company evaluates the lease terms to determine whether the lease will be accounted
for as an operating or finance lease. Operating leases are included in operating lease right-of-use (“ROU”) assets,
operating lease liabilities, current portion, and operating lease liabilities, net of current portion in our consolidated balance
sheets.
ROU assets represent
our right to use an underlying asset for the lease term, and lease liabilities represent our obligation to make lease payments
arising from the lease. Operating lease ROU assets and liabilities are recognized at commencement date based on the present value
of lease payments over the lease term. As most of our leases do not provide an implicit rate, we use our incremental borrowing
rate based on the information available at commencement date in determining the present value of lease payments. The Company uses
the implicit rate when readily determinable. The operating lease ROU asset also includes any lease payments made and excludes lease
incentives. Our lease terms may include options to extend or terminate the lease when it is reasonably certain that we will exercise
that option. Lease expense for lease payments is recognized on a straight-line basis over the lease term.
A lease that transfers
substantially all of the benefits and risks incidental to ownership of property are accounted for as finance leases. At the inception
of a finance lease, an asset and finance lease obligation is recorded at an amount equal to the lesser of the present value of
the minimum lease payments and the property’s fair market value. Finance lease obligations are classified as either current
or long-term based on the due dates of future minimum lease payments, net of interest. At June 30, 2023 and December 31, 2022,
there were no finance leases.
|
Research and Development |
Research and Development
The Company accounts
for research and development costs in accordance with ASC 730-10, Research and Development (“ASC 730-10”).
Under ASC 730-10, all research and development costs must be charged to expense as incurred. Accordingly, internal research and
development costs are expensed as incurred. Third-party research and development costs are expensed when the contracted work has
been performed or as milestone results have been achieved. Research and development expenses include salaries and benefits, facilities
and other overhead expense, external clinical trial expenses, research related manufacturing services, contract services and other
outside expenses.
|
Patent Costs and Rights |
Patent Costs and Rights
Costs of applying for,
prosecuting and maintaining patents and patent rights are expensed as incurred due to uncertainty of future economic benefit.
|
Clinical Trial Costs |
Clinical Trial Costs
Clinical trial costs
are charged to us and recognized as the tasks are completed by the contractor(s) or, alternatively, may be invoiced in accordance
with agreed-upon payment schedules and recognized based on estimates of work completed to date.
|
Stock Option Compensation Expense |
Stock Option Compensation Expense
The Company recognizes the fair value of stock option award expenses on a straight-line basis over a service
period of three years, consistent with vesting periods, using the Black-Scholes options pricing model to estimate the fair value
of option awards. Such expenses are categorized as research and development or general and administrative depending on the role
of each option recipient.
The Company recognizes
the income tax benefits and deficiencies as income tax expense or benefit in the statement of operations and the tax effects of
exercised or vested awards are treated as discrete items in the reporting period in which they occur. The Company also recognizes
excess tax benefits regardless of whether the benefit reduces taxes payable in the current period. Excess tax benefits are classified
along with other income tax cash flows as an operating activity in the statement of cash flows. Regarding forfeitures, the Company
accounts for them when they occur. See Note 9 for more information on our stock options.
|
Warrants |
Warrants
The Company accounts
for Common Stock warrants as either liabilities or as equity instruments depending on the specific terms of the warrant agreements.
Generally, warrants are classified as liabilities, as opposed to equity, if the agreement includes the potential for a cash settlement
or an adjustment to the exercise price, and warrant liabilities are recorded at their fair values at each balance sheet date. See
Note 12 related to issued warrants.
|
Income Taxes |
Income Taxes
The Company accounts
for income taxes in accordance with the asset and liability method of accounting for income taxes prescribed by FASB ASC Topic
740, “Accounting for Income Taxes” (“ASC 740”). Under the asset and liability method of ASC 740,
deferred tax assets and liabilities are recognized for the future tax consequences attributable to differences between the financial
statement carrying amounts of existing assets and liabilities and their respective tax basis and operating loss and tax credit
carry-forwards. Deferred tax assets and liabilities are measured using enacted tax rates expected to apply to the taxable income
in the years in which those temporary differences are expected to be recovered or settled. Under ASC 740, the effect on deferred
tax assets and liabilities of a change in tax rates is recognized in income in the period that includes the enactment dates. The
Company evaluates its deferred income taxes to determine if a valuation allowance should be established against the deferred tax
assets or if the valuation allowance should be reduced based on consideration of all available evidence, both positive and negative,
using a “more likely than not” standard.
The Company follows
FASB ASC Topic 740-10, “Accounting for Uncertainty in Income Taxes” (“Topic 740-10”), which prescribes
a recognition threshold and measurement attribute for financial statement recognition and measurement of a tax position taken,
or expected to be taken, in a tax return. For those benefits to be recognized, a tax position must be more likely than not to be
sustained upon examination by taxing authorities. At June 30, 2023 and December 31, 2022, the Company had no material uncertain
tax positions to be accounted for in the financial statements. The Company recognizes interest and penalties, if any, related to
unrecognized tax benefits in interest expense. See Note 14 related to income taxes.
|
Concentration of Credit Risk |
Concentration of Credit Risk
The
Company’s grant revenues and grant receivables were with the NIH. The NIH is an agency of the United States Department of
Health & Human Services, and the Company believes amounts are fully collectible from this agency. Contract revenues were $224,724
for the six months ended June 30, 2023, and $106,676 for the three months ended June 30, 2023.
|
Earnings Per Share |
Earnings Per Share
Basic
net loss per share of Common Stock is computed by dividing the net loss for the period by the weighted-average number of
shares of Common Stock outstanding during the period. Diluted net loss per common share is computed giving effect to all dilutive
Common Stock equivalents, consisting of stock options and warrants. Diluted net loss per share of Common Stock for the six months
ended June 30, 2023 and 2022 is the same as basic net loss per share, as the Common Stock equivalents were anti-dilutive due to
the net loss.
Due to the Stock Split, the shares outstanding
at June 30, 2022 have been retroactively adjusted, reducing them from 9,666,562 to 3,866,625. This had a corresponding increase
in the loss per share of Common Stock from $0.16 to $0.39 per share for the six months ended June 30, 2022, and from $0.08 to $0.20
per share for the three months ended June 30, 2022.
At June 30, 2023 and 2022, the Common Stock equivalent shares
were, as follows:
Schedule of common stock equivalent shares
| |
|
|
|
|
|
| |
| |
June
30, | |
| |
2023 | | |
2022 | |
Shares
of Common Stock issuable under equity incentive plans outstanding | |
| 2,478,000 | | |
| 2,054,000 | |
Shares of Common Stock
issuable upon exercise of warrants
| |
| 143,994 | | |
| 143,994 | |
Shares
of Common Stock issuable upon conversion of Series A Preferred Stock | |
| — | | |
| 636,979 | |
Common
Stock equivalent shares excluded from diluted net loss per share | |
| 2,621,994 | | |
| 2,834,973 | |
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v3.23.2
Summary of Significant Accounting Policies (Tables)
|
6 Months Ended |
Jun. 30, 2023 |
Accounting Policies [Abstract] |
|
Schedule of common stock equivalent shares |
At June 30, 2023 and 2022, the Common Stock equivalent shares
were, as follows:
Schedule of common stock equivalent shares
| |
|
|
|
|
|
| |
| |
June
30, | |
| |
2023 | | |
2022 | |
Shares
of Common Stock issuable under equity incentive plans outstanding | |
| 2,478,000 | | |
| 2,054,000 | |
Shares of Common Stock
issuable upon exercise of warrants
| |
| 143,994 | | |
| 143,994 | |
Shares
of Common Stock issuable upon conversion of Series A Preferred Stock | |
| — | | |
| 636,979 | |
Common
Stock equivalent shares excluded from diluted net loss per share | |
| 2,621,994 | | |
| 2,834,973 | |
|
X |
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v3.23.2
Fair Value Measurements and Marketable Debt Securities (Tables)
|
6 Months Ended |
Jun. 30, 2023 |
Fair Value Disclosures [Abstract] |
|
For cash equivalents at June 30, 2023 the fair value input levels are summarized below: |
The Company held no
marketable securities or cash equivalents at December 31, 2022, and no marketable securities at June 30, 2023. For cash equivalents
at June 30, 2023 the fair value input levels are summarized below:
June 30, 2023 | |
Level 1 | | |
Level 2 | | |
Level 3 | | |
Total | |
Cash Equivalents (maturity less than 90 days) | |
| | | |
| | | |
| | | |
| | |
Commercial Paper | |
$ | — | | |
| — | | |
| — | | |
$ | — | |
U.S. Government | |
| — | | |
| — | | |
| — | | |
| — | |
Money market funds | |
| 2,801,063 | | |
| — | | |
| — | | |
| 2,801,063 | |
Total Cash equivalents | |
| 2,801,063 | | |
| | | |
| | | |
| 2,801,063 | |
| |
| | | |
| | | |
| | | |
| | |
Marketable Securities | |
| — | | |
| — | | |
| — | | |
| — | |
Total Cash Equivalents and Marketable Securities | |
$ | 2,801,063 | | |
$ | — | | |
$ | — | | |
$ | 2,801,063 | |
|
X |
- DefinitionTabular disclosure of the fair value of financial instruments, including financial assets and financial liabilities, and the measurements of those instruments, assets, and liabilities.
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v3.23.2
Notes Payable – Related Party (Tables)
|
6 Months Ended |
Jun. 30, 2023 |
Debt Disclosure [Abstract] |
|
The note obligation and accrued interest are provided in the following table. |
The note obligation and accrued interest are provided in the following table.
Origination | | |
Original Principal | | |
Current Principal | | |
Rate | | |
Maturity | | |
Accrued Interest - Related Party December 31, 2022 | | |
Accrued Interest - Related Party March 31, 2023 | | |
Accrued Interest - Related Party June 30, 2023 | | |
Category | |
November 1, 2022 | | |
$ | 250,000 | | |
$ | - | | |
| 8.75 | % | |
| 06/30/23 | | |
$ | 3,596 | | |
$ | 8,990 | | |
$ | — | | |
| Current | |
|
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v3.23.2
Stock Options (Tables)
|
6 Months Ended |
Jun. 30, 2023 |
Share-Based Payment Arrangement [Abstract] |
|
The following is an analysis of options to purchase shares of Common Stock issued and outstanding as of June 30, 2023 and December 31, 2022: |
The following is an analysis of options to purchase shares of Common Stock issued and outstanding as of
June 30, 2023 and December 31, 2022:
| |
Shares | | |
Weighted- Average Exercise Price Per Share ($) | | |
Weighted- Average Remaining Contractual Term (in Years) | | |
Aggregate intrinsic value ($) | |
Outstanding as of December 31, 2021 | |
| 2,044,000 | | |
| 2.82 | | |
| 6.61 | | |
| 4,446,667 | |
Granted | |
| 10,0000 | | |
| 5.00 | | |
| 9.16 | | |
| | |
Expired | |
| — | | |
| | | |
| | | |
| | |
Cancelled | |
| — | | |
| | | |
| | | |
| | |
Exercised | |
| — | | |
| | | |
| | | |
| | |
Outstanding as of December 31, 2022 | |
| 2,054,000 | | |
| 2.84 | | |
| 5.51 | | |
| 605,687 | |
Granted | |
| — | | |
| | | |
| | | |
| | |
Expired | |
| — | | |
| | | |
| | | |
| | |
Cancelled | |
| — | | |
| | | |
| | | |
| | |
Exercised | |
| — | | |
| | | |
| | | |
| | |
Outstanding as of March 31, 2023 | |
| 2,054,000 | | |
| 2.84 | | |
| 5.26 | | |
$ | — | |
Granted | |
| 424,000 | | |
| 2.19 | | |
| 9.96 | | |
| | |
Expired | |
| — | | |
| | | |
| | | |
| | |
Cancelled | |
| — | | |
| | | |
| | | |
| | |
Exercised | |
| — | | |
| | | |
| | | |
| | |
Outstanding as of June 30, 2023 | |
| 2,478,000 | | |
| 2.72 | | |
| 5.86 | | |
$ | — | |
Vested as of June 30, 2023 | |
| 2,190,667 | | |
| | | |
| | | |
| | |
Exercisable as of June 30, 2023 | |
| 2,190,667 | | |
| | | |
| | | |
| | |
Exercisable as of December 31, 2022 | |
| 1,619,333 | | |
| | | |
| | | |
| | |
|
A summary of status of the Company’s non-vested stock options (exercisable for shares of Common Stock on a one-to-one basis) as of, and changes during, the six months ended June 30, 2023 and 2022 is presented below: |
A
summary of status of the Company’s non-vested stock options (exercisable for shares of Common Stock on a one-to-one basis)
as of, and changes during, the six months ended June 30, 2023 and 2022 is presented below:
| |
Number of Stock Options | | |
Weighted- Average Fair Value Grant Date | |
Nonvested at December 31, 2021 | |
| 688,667 | | |
$ | 2.82 | |
Granted | |
| 10,000 | | |
$ | 2.84 | |
Vested | |
| (157,333 | ) | |
$ | 2.83 | |
Expired | |
| — | | |
$ | 0.00 | |
Nonvested at June 30, 2022 | |
| 541,333 | | |
$ | 2.82 | |
| |
| | | |
| | |
Nonvested at December 31, 2022 | |
| 434,667 | | |
$ | 2.82 | |
Granted | |
| 424,000 | | |
| 2.19 | |
Vested | |
| (423,334 | ) | |
| 2.83 | |
Expired | |
| — | | |
| — | |
Nonvested at June 30, 2023 | |
| 435,333 | | |
$ | 2.81 | |
|
The weighted-average fair value of stock options on the date of grant and the assumptions used to estimate the fair value of stock options granted during the six months ended June 30, 2023 and June 30, 2022 using the Black-Scholes option-pricing model is as follows: |
The
weighted-average fair value of stock options on the date of grant and the assumptions used to estimate the fair value of stock
options granted during the six months ended June 30, 2023 and June 30, 2022 using the Black-Scholes option-pricing model is as
follows:
Six months ended June 30: | |
2023 | | |
2022 | |
Weighted-average fair value of options granted | |
$ | 1.50 | | |
| 1.14 | |
Expected volatility | |
| 83.47 | % | |
| 75 | % |
Expected life (in years) | |
| 5.04 | | |
| 10 | |
Risk-free interest rate (range) | |
| 3.99 | % | |
| 2.31 | % |
Expected dividend yield | |
$ | — | | |
| — | |
|
X |
- DefinitionTabular disclosure of activity for outstanding award under share-based payment arrangement excluding share and unit options and nonvested award.
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v3.23.2
Commitment and Contingencies (Tables)
|
6 Months Ended |
Jun. 30, 2023 |
Commitments and Contingencies Disclosure [Abstract] |
|
Future minimum rent payments under the Lease as of June 30, 2023 are as follows: |
The
Company entered into a lease agreement beginning July 1, 2020, for the Company’s principal headquarters at 7800 Susquehanna
Street, Pittsburgh, Pennsylvania, which includes office space and sterile manufacturing operations (the “Lease”).
The Lease has a five-year term and includes an option for renewal, which is not reasonably certain and is excluded from the right
of use calculation. Future minimum rent payments under the Lease as of June 30, 2023 are as follows:
Year ending | |
| |
2023 (6 months remaining) | |
$ | 33,476 | |
2024 | |
$ | 67,289 | |
2025 | |
$ | 33,813 | |
Total minimum lease payments | |
$ | 134,578 | |
Less: amount representing interest | |
$ | (8,400 | ) |
Present value of minimum lease payments | |
$ | 126,178 | |
|
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v3.23.2
Going Concern (Details Narrative) - USD ($)
|
3 Months Ended |
6 Months Ended |
12 Months Ended |
Jun. 30, 2023 |
Mar. 31, 2023 |
Jun. 30, 2022 |
Mar. 31, 2022 |
Jun. 30, 2023 |
Jun. 30, 2022 |
Dec. 31, 2022 |
Organization, Consolidation and Presentation of Financial Statements [Abstract] |
|
|
|
|
|
|
|
Net loss |
$ (1,538,686)
|
$ (1,067,825)
|
$ (782,024)
|
$ (737,950)
|
$ (2,606,511)
|
$ (1,519,975)
|
$ (2,597,692)
|
Accumulated deficit |
(8,311,389)
|
|
|
|
(8,311,389)
|
|
(5,704,878)
|
Cash and cash equivalents |
3,113,644
|
|
|
|
3,113,644
|
|
$ 5,121,743
|
Working capital deficit |
$ 3,068,186
|
|
|
|
$ 3,068,186
|
|
|
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|
6 Months Ended |
Jun. 30, 2023 |
Jun. 30, 2022 |
Accounting Policies [Abstract] |
|
|
Shares of Common Stock issuable under equity incentive plans outstanding |
2,478,000
|
2,054,000
|
Shares of Common Stock issuable upon exercise of warrants |
143,994
|
143,994
|
Shares of Common Stock issuable upon conversion of Series A Preferred Stock |
|
636,979
|
Common Stock equivalent shares excluded from diluted net loss per share |
2,621,994
|
2,834,973
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v3.23.2
Summary of Significant Accounting Policies (Details Narrative) - USD ($)
|
3 Months Ended |
6 Months Ended |
|
Jun. 30, 2023 |
Jun. 30, 2022 |
Jun. 30, 2023 |
Jun. 30, 2022 |
Dec. 31, 2022 |
Property, Plant and Equipment [Line Items] |
|
|
|
|
|
Long-lived assets |
$ 125,859
|
|
$ 125,859
|
|
$ 125,859
|
Revenues |
$ 106,676
|
|
$ 224,724
|
$ 33,149
|
|
Weighted-average common shares outstanding |
5,743,945
|
3,866,625
|
5,743,945
|
3,866,625
|
|
Maximum [Member] |
|
|
|
|
|
Property, Plant and Equipment [Line Items] |
|
|
|
|
|
Anti-dilutive shares |
|
|
|
9,666,562
|
|
Loss per share of common stock |
|
$ 0.20
|
|
$ 0.39
|
|
Minimum [Member] |
|
|
|
|
|
Property, Plant and Equipment [Line Items] |
|
|
|
|
|
Weighted-average common shares outstanding |
|
|
|
3,866,625
|
|
Loss per share of common stock |
|
$ 0.08
|
|
$ 0.16
|
|
X |
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v3.23.2
For cash equivalents at June 30, 2023 the fair value input levels are summarized below: (Details)
|
Jun. 30, 2023
USD ($)
|
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |
|
Cash equivalents |
$ 2,801,063
|
Marketable Securities |
|
Total Cash Equivalents and Marketable Securities |
2,801,063
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2,801,063
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|
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |
|
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2,801,063
|
Marketable Securities |
|
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2,801,063
|
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|
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|
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|
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |
|
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|
Fair Value, Inputs, Level 1 [Member] | Money Market Funds [Member] |
|
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |
|
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2,801,063
|
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|
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] |
|
Marketable Securities |
|
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|
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|
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v3.23.2
The following is an analysis of options to purchase shares of Common Stock issued and outstanding as of June 30, 2023 and December 31, 2022: (Details) - USD ($)
|
3 Months Ended |
6 Months Ended |
12 Months Ended |
Jun. 30, 2023 |
Mar. 31, 2023 |
Jun. 30, 2023 |
Jun. 30, 2022 |
Dec. 31, 2022 |
Dec. 31, 2021 |
Share-Based Payment Arrangement [Abstract] |
|
|
|
|
|
|
Outstanding at beginning |
2,054,000
|
2,054,000
|
2,054,000
|
2,044,000
|
2,044,000
|
|
Outstanding at beginning |
$ 2.84
|
$ 2.84
|
$ 2.84
|
$ 2.82
|
$ 2.82
|
|
Outstanding at ending (in years) |
6 years 7 months 10 days
|
6 years 7 months 10 days
|
|
|
6 years 7 months 10 days
|
6 years 7 months 10 days
|
Outstanding at beginning |
|
|
|
$ 605,687
|
$ 605,687
|
$ 4,446,667
|
Granted |
424,000
|
|
|
|
100,000
|
|
Granted |
$ 2.19
|
|
$ 2.19
|
$ 2.84
|
$ 5.00
|
|
Granted (in years) |
|
9 years 11 months 15 days
|
|
|
9 years 1 month 27 days
|
|
Expired |
|
|
|
|
|
|
Cancelled |
|
|
|
|
|
|
Exercised |
|
|
|
|
|
|
Outstanding at ending |
2,478,000
|
2,054,000
|
2,478,000
|
|
2,054,000
|
2,044,000
|
Outstanding at ending |
$ 2.72
|
$ 2.84
|
$ 2.72
|
|
$ 2.84
|
$ 2.82
|
Outstanding at ending |
|
|
|
|
|
$ 605,687
|
Options vested |
2,190,667
|
|
2,190,667
|
|
|
|
Options exercisable |
2,190,667
|
|
2,190,667
|
|
1,619,333
|
|
X |
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- DefinitionGross number of share options (or share units) granted during the period.
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- DefinitionThe weighted average grant-date fair value of options granted during the reporting period as calculated by applying the disclosed option pricing methodology.
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- DefinitionNumber of options outstanding, including both vested and non-vested options.
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- DefinitionWeighted average price at which grantees can acquire the shares reserved for issuance under the stock option plan.
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v3.23.2
A summary of status of the Company’s non-vested stock options (exercisable for shares of Common Stock on a one-to-one basis) as of, and changes during, the six months ended June 30, 2023 and 2022 is presented below: (Details) - $ / shares
|
3 Months Ended |
6 Months Ended |
12 Months Ended |
Jun. 30, 2023 |
Jun. 30, 2023 |
Jun. 30, 2022 |
Dec. 31, 2022 |
Share-Based Payment Arrangement [Abstract] |
|
|
|
|
Nonvested at beginning |
|
434,667
|
688,667
|
688,667
|
Nonvested at beginning |
|
$ 2.82
|
$ 2.82
|
$ 2.82
|
Granted |
|
424,000
|
10,000
|
|
Granted |
$ 2.19
|
$ 2.19
|
$ 2.84
|
$ 5.00
|
Vested |
|
(423,334)
|
(157,333)
|
|
Vested |
|
$ 2.83
|
$ 2.83
|
|
Expired |
|
|
|
|
Expired |
|
|
$ 0.00
|
|
Nonvested at ending |
435,333
|
435,333
|
541,333
|
434,667
|
Nonvested at ending |
$ 2.81
|
$ 2.81
|
$ 2.82
|
$ 2.82
|
X |
- DefinitionThe element represents share based compensation arrangement by share based payment award options expirations in period1.
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- DefinitionThe weighted average grant-date fair value of options granted during the reporting period as calculated by applying the disclosed option pricing methodology.
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v3.23.2
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- DefinitionThe estimated amount of dividends to be paid to holders of the underlying shares (expected dividends) over the option's term. Dividends are taken into account because payment of dividends to shareholders reduces the fair value of the underlying shares, and option holders generally do not receive dividends.
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instant |
|
v3.23.2
Stock Options (Details Narrative) - USD ($)
|
|
|
3 Months Ended |
6 Months Ended |
12 Months Ended |
Jun. 16, 2023 |
Mar. 01, 2022 |
Jun. 30, 2023 |
Mar. 31, 2023 |
Jun. 30, 2022 |
Jun. 30, 2023 |
Jun. 30, 2022 |
Dec. 31, 2022 |
Dec. 31, 2021 |
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] |
|
|
|
|
|
|
|
|
|
Common stock, shares, issued |
|
|
5,743,945
|
|
|
5,743,945
|
|
5,743,945
|
|
Common stock, shares, oustanding |
|
|
5,743,945
|
|
|
5,743,945
|
|
5,743,945
|
|
Expected term (in years) |
|
|
|
|
|
5 years 15 days
|
10 years
|
|
|
Weighted average remaining contractual life |
|
|
6 years 7 months 10 days
|
6 years 7 months 10 days
|
|
|
|
6 years 7 months 10 days
|
6 years 7 months 10 days
|
Stock Option Plans [Member] |
|
|
|
|
|
|
|
|
|
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] |
|
|
|
|
|
|
|
|
|
Common stock, shares, issued |
424,000
|
10,000
|
|
|
|
|
|
|
|
Expected term (in years) |
|
|
|
|
|
10 years
|
|
|
|
Unrecognized compensation |
|
|
$ 806,157
|
|
|
$ 806,157
|
|
$ 1,222,500
|
|
Weighted average remaining contractual life |
|
|
|
|
|
18 months
|
|
|
|
Compensation cost |
|
|
$ 847,618
|
|
$ 213,489
|
$ 1,056,257
|
$ 448,637
|
|
|
Strike price |
$ 2.19
|
$ 5.00
|
|
|
|
|
|
|
|
Common Class A [Member] | Stock Option Plans [Member] |
|
|
|
|
|
|
|
|
|
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] |
|
|
|
|
|
|
|
|
|
Common stock, shares, issued |
|
|
2,478,000
|
|
|
2,478,000
|
|
|
|
Common Class A [Member] | Stock Option Plans 2008 [Member] |
|
|
|
|
|
|
|
|
|
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] |
|
|
|
|
|
|
|
|
|
Common stock, shares, oustanding |
|
|
1,078,000
|
|
|
1,078,000
|
|
|
|
Common Class A [Member] | Stock Option Plans 2020 [Member] |
|
|
|
|
|
|
|
|
|
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] |
|
|
|
|
|
|
|
|
|
Common stock, shares, issued |
|
|
1,400,000
|
|
|
1,400,000
|
|
|
|
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v3.23.2
Preferred Stock (Details Narrative) - USD ($)
|
6 Months Ended |
12 Months Ended |
Jun. 30, 2023 |
Dec. 31, 2022 |
Accumulated Other Comprehensive Income (Loss) [Line Items] |
|
|
Preferred stock, shares authorized |
20,000,000
|
20,000,000
|
Preferred stock, par or stated value per share |
$ 0.0001
|
$ 0.0001
|
Stock per share |
$ 0.0001
|
$ 0.0001
|
Description of shaes conversion |
all of the Series
A Stock would have automatically converted into Common Stock upon any one of the following three conditions: a public offering
of at least $7,000,000 of gross proceeds, the optional conversion of at least 80% of issued shares of Series A Stock, or the consent
of holders of a majority of the Series A Stock. The shares of Series A Stock have average-weighted anti-dilution protection that
becomes effective upon the issuance of Common Stock (or securities convertible into Common Stock) at a price below $0.60 per share.
|
|
Shares outstanding converted |
0
|
0
|
Series A Preferred Stock [Member] |
|
|
Accumulated Other Comprehensive Income (Loss) [Line Items] |
|
|
Preferred stock, shares authorized |
5,000,000
|
|
Preferred stock, par or stated value per share |
$ 0.0001
|
|
Common Class A [Member] |
|
|
Accumulated Other Comprehensive Income (Loss) [Line Items] |
|
|
Liquidation preference amount |
$ 0
|
$ 0
|
Shares outstanding converted |
|
1,592,447
|
Common Class A [Member] | Maximum [Member] |
|
|
Accumulated Other Comprehensive Income (Loss) [Line Items] |
|
|
Stock per share |
|
$ 0.60
|
Preferred Stock [Member] |
|
|
Accumulated Other Comprehensive Income (Loss) [Line Items] |
|
|
Preferred stock, shares authorized |
20,000,000
|
|
Preferred stock, par or stated value per share |
$ 0.0001
|
|
Common Stock [Member] |
|
|
Accumulated Other Comprehensive Income (Loss) [Line Items] |
|
|
Shares converted |
|
636,979
|
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v3.23.2
Common Stock (Details Narrative) - USD ($)
|
|
12 Months Ended |
|
Dec. 22, 2022 |
Dec. 31, 2022 |
Jun. 30, 2023 |
Accumulated Other Comprehensive Income (Loss) [Line Items] |
|
|
|
Common stock, shares authorized |
|
200,000,000
|
200,000,000
|
Common stock, shares outstanding |
|
5,743,945
|
5,743,945
|
Common stock, shares issued |
|
5,743,945
|
5,743,945
|
IPO [Member] |
|
|
|
Accumulated Other Comprehensive Income (Loss) [Line Items] |
|
|
|
Proceeds from initial public offering |
$ 5,000,000
|
|
|
Underwriting fees |
630,000
|
|
|
Offering expense |
$ 1,160,000
|
|
|
Common Stock [Member] |
|
|
|
Accumulated Other Comprehensive Income (Loss) [Line Items] |
|
|
|
Common stock, shares authorized |
|
|
200,000,000
|
Common stock, shares outstanding |
|
5,743,945
|
5,743,945
|
Accrued interest |
|
$ 138,810
|
|
Common Stock [Member] | IPO [Member] |
|
|
|
Accumulated Other Comprehensive Income (Loss) [Line Items] |
|
|
|
Common stock, shares issued |
1,217,391
|
|
|
Shares issued, price per share |
$ 5.75
|
|
|
Common Stock One [Member] |
|
|
|
Accumulated Other Comprehensive Income (Loss) [Line Items] |
|
|
|
Common stock, shares issued |
|
22,950
|
|
X |
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v3.23.2
Commitment and Contingencies (Details Narrative)
|
1 Months Ended |
Feb. 28, 2022 |
Commitments and Contingencies Disclosure [Abstract] |
|
Commitments description |
The Company paid $10,000 per month for the first four months of the agreement’s term. The agreement (which was terminated
in June 2022), included a surviving success fee, such that in the event of a successful transaction occurring prior to September
2023, required the Company to make a payment equal to the greater of (a) five percent of the transaction value and (b) $500,000.
For the three months ended June 30, 2023, and June 30, 2022, the Company has recorded $0 and $30,000, respectively, in general
and administrative expense related to this commitment, and has not recorded any additional liabilities related to the surviving
success fee clause as of the balance sheet date.
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v3.23.2
v3.23.2
Subsequent Events (Details Narrative)
|
Aug. 01, 2023 |
Subsequent Event [Member] |
|
Subsequent Event [Line Items] |
|
Description of subsequent event |
Effective August 1, 2023, the Company became party to a lease for additional space at their current
location (the “August 2023 Lease”). The August 2023 Lease will co-terminate with the Lease on June 30, 2025, with an option to extend for five years. Under
the August 2023 Lease, the Company expects to pay an additional $11,483 in rent during the calendar year 2023.
|
X |
- DefinitionDescribes the event or transaction that occurred between the balance sheet date and the date the financial statements are issued or available to be issued.
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