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Spero Therapeutics Inc

Spero Therapeutics Inc (SPRO)

1.14
0.008
(0.71%)
Closed November 30 3:00PM
1.14
0.00
(0.00%)
After Hours: 3:35PM

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Key stats and details

Current Price
1.14
Bid
1.13
Ask
1.19
Volume
90,870
1.11 Day's Range 1.2401
1.01 52 Week Range 1.89
Market Cap
Previous Close
1.132
Open
1.15
Last Trade
10
@
1.19
Last Trade Time
Financial Volume
US$ 102,589
VWAP
1.129
Average Volume (3m)
252,597
Shares Outstanding
54,049,139
Dividend Yield
-
PE Ratio
2.70
Earnings Per Share (EPS)
0.42
Revenue
103.78M
Net Profit
22.81M

About Spero Therapeutics Inc

Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is de... Spero Therapeutics Inc is a clinical-stage biopharmaceutical firm. It focuses on identifying, developing and commercializing novel treatments for MDR (Multi-drug-resistant) bacterial infections and rare diseases. The company's product candidate, tebipenem pivoxil hydrobromide or tebipenem HBr, is designed to be an oral carbapenem-class antibiotic for use in adults to treat MDR Gram-negative infections. It is also developing SPR720, a novel oral antibiotic designed for the treatment of a rare, orphan disease caused by pulmonary non-tuberculous mycobacterial infections, or NTM disease. Besides, it is also focused on SPR206, a next-generation polymyxin investigational product candidate, being developed as an IV-administered medicine to treat MDR Gram-negative infections in the hospital. Show more

Sector
Pharmaceutical Preparations
Industry
Pharmaceutical Preparations
Headquarters
Wilmington, Delaware, USA
Founded
-
Spero Therapeutics Inc is listed in the Pharmaceutical Preparations sector of the NASDAQ with ticker SPRO. The last closing price for Spero Therapeutics was US$1.13. Over the last year, Spero Therapeutics shares have traded in a share price range of US$ 1.01 to US$ 1.89.

Spero Therapeutics currently has 54,049,139 shares outstanding. The market capitalization of Spero Therapeutics is US$61.18 million. Spero Therapeutics has a price to earnings ratio (PE ratio) of 2.70.

SPRO Latest News

Spero Therapeutics Announces Third Quarter 2024 Operating Results and Provides a Business Update

Phase 3 PIVOT-PO trial of tebipenem HBr remains on track to complete enrollment in 2H 2025 Reiterate cash runway into mid-2026; Q3 2024 ending cash balance of $76.3M CAMBRIDGE, Mass., Nov. 14...

Spero Therapeutics to Report Third Quarter 2024 Financial Results and Provide Business Update on Thursday, November 14, 2024

CAMBRIDGE, Mass., Nov. 07, 2024 (GLOBE NEWSWIRE) -- Spero Therapeutics, Inc. (Nasdaq: SPRO), a multi-asset clinical-stage biopharmaceutical company, focused on identifying and developing novel...

Spero Therapeutics Announces SPR720 Phase 2a Interim Results and Provides a Business Update

Phase 2a proof-of-concept study of SPR720 for the treatment of Nontuberculous Mycobacterial Pulmonary Disease (NTM-PD) did not meet its primary endpoint, based on planned interim analysis of 16...

Spero Therapeutics Announces Presentation of SPR719 (Active Moiety of SPR720) In Vitro Data Demonstrating Low Propensity for the Development of Resistance at IDWeek 2024

In vitro data on SPR719 show low propensity for resistance development in NTM-PD MAC strains when administered as a single agent and in combination with standard of care agents Study highlighting...

Spero Therapeutics Announces Publication of SPR720 Phase 1 Lung Exposure Data in Antimicrobial Agents and Chemotherapy

CAMBRIDGE, Mass., Oct. 02, 2024 (GLOBE NEWSWIRE) -- Spero Therapeutics, Inc.Β (Nasdaq: SPRO), a multi-asset clinical-stage biopharmaceutical company, focused on identifying and developing novel...

Spero Therapeutics to Present at Upcoming September Investor Conferences

CAMBRIDGE, Mass., Sept. 04, 2024 (GLOBE NEWSWIRE) -- Spero Therapeutics, Inc. (Nasdaq: SPRO) (Spero), a multi-asset clinical-stage biopharmaceutical company, focused on identifying, developing...

PeriodChangeChange %OpenHighLowAvg. Daily VolVWAP
1-0.05-4.201680672271.191.231.12871231.15070995CS
4-0.07-5.785123966941.211.341.13126471.21463437CS
12-0.18-13.63636363641.321.421.012525971.25815979CS
26-0.28-19.71830985921.421.531.011888751.29348816CS
52-0.02-1.724137931031.161.891.012188321.45587226CS
156-14.32-92.626131953415.4616.30.68019715541.95712292CS
260-10.73-90.395956192111.8723.6390.68016582103.4146271CS

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SPRO Discussion

View Posts
Monksdream Monksdream 3 months ago
SPRO under $2
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Monksdream Monksdream 4 months ago
SPRO under $2
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Monksdream Monksdream 7 months ago
SPRO under $2
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Monksdream Monksdream 9 months ago
SPRO under $2
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glenn1919 glenn1919 9 months ago
SPRO...................................https://stockcharts.com/h-sc/ui?s=SPRO&p=W&b=5&g=0&id=p86431144783
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Monksdream Monksdream 9 months ago
SPRO 10Q due March 13
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Monksdream Monksdream 9 months ago
SPRO under $2
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Monksdream Monksdream 1 year ago
SPRO new 52 week low
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Monksdream Monksdream 1 year ago
SPRO new 52 week low
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Monksdream Monksdream 1 year ago
SPRO new 52 week low
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Monksdream Monksdream 1 year ago
SPRO under $2
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Awl416 Awl416 1 year ago
News?
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m0n m0n 1 year ago
$SPRO YuuuuGE FDA News

Spero Therapeutics shares were up 14% at $1.62 after the company received written agreement from the U.S. Food and
Drug Administration, under a Special Protocol Assessment, on the design and size of its pivotal Phase 3 clinical trial
of tebipenem HBr in patients with complicated urinary tract infection, including acute pyelonephritis.
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81vette 81vette 2 years ago
Urinary tract infection drug,$66m reviewed up to 525m coming,royalties on sales is astronomical
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81vette 81vette 2 years ago
Pfizer paid $5m of $40 and $80m total coming for license agreement,many more deals coming ,some phase 3 trials near done OMG THE BIG DEALS COMING
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81vette 81vette 2 years ago
Look at the candle on this chart 6 month record high,now look back to see what happens with big vol
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81vette 81vette 2 years ago
Look at the candle on this chart 6 month record high,now look back to see what happens with big vol
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81vette 81vette 2 years ago
Relative vol up 28Xs ,buy vol up 1000s% I AM FOLLOWING THE $ ppl with big $ know something huge coming
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81vette 81vette 2 years ago
Relative vol up 28Xs ,buy vol up 1000s% I AM FOLLOWING THE $ ppl with big $ know something huge coming
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saigai saigai 2 years ago
ive had some strange experiences with stocks but this one has me baffled but not beaten..
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saigai saigai 2 years ago
someone just unloaded a boat load and or shorted same. halfway around the cape and battered by high winds but not going anywhere. i cant
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saigai saigai 2 years ago
they will short this back down to .80 at this rate . eff me
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saigai saigai 2 years ago
folks keep walking away.. day after day after day.. ill be here im lashed to the mast of this bark as we get blistered around the cape
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saigai saigai 2 years ago
damn heavy unloading
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saigai saigai 2 years ago
big volume crashing again.. and i thought i was smart.. hahahahahastill bullish
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saigai saigai 2 years ago
must be some kind of inside news. this keeps falling and i dont get it.. but too late now .. this is the hill i die on or
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saigai saigai 2 years ago
a little retail short covering for the green. ill take it
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saigai saigai 2 years ago
another day of heavy downside volume in the cards..not good
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saigai saigai 2 years ago
shorts in control
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StockLogistics StockLogistics 2 years ago
GSK believed in SPRO enough to pay over 60 million at once, when investors get the same belief level it would in theory skyrocket, risk/reward and forward expectations are supposed to partially drive share price along with cash available to reduce risk of dilution, cash which GSK provided.
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StockLogistics StockLogistics 2 years ago
GSK believed in SPRO enough to pay over 60 million at once, when investors get the same belief level it would in theory skyrocket, risk/reward and forward expectations are supposed to partially drive share price along with cash available to reduce risk of dilution, cash which GSK provided.
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saigai saigai 2 years ago
a little run into earnings. ill hold through it and beyond
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saigai saigai 2 years ago
https://finance.yahoo.com/news/spero-therapeutics-announces-closing-exclusive-130500913.html
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saigai saigai 2 years ago
maybe we get some interest from this
https://finance.yahoo.com/news/spero-therapeutics-inc-spro-expected-140102871.html
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saigai saigai 2 years ago
ill be here when the mkt cap is over a billion
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saigai saigai 2 years ago
https://finance.yahoo.com/news/spero-therapeutics-present-data-idweek-120500461.html
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saigai saigai 2 years ago
almost no pre opening trading...the waters have stilled.. it wont stay calm for long ..lets see which way it breaks
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saigai saigai 2 years ago
bought more i wont be bought off with impatience
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saigai saigai 2 years ago
enter the flipper
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saigai saigai 2 years ago
just when you have given up hope a volume burst and a price pop
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StockLogistics StockLogistics 2 years ago
Macd on one month about to cross lower unless they have premarket news, many will sell premarket without news so if they have something releasing it premarket would be best for loyal shareholders who would miss out on a new release later in the session.
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saigai saigai 2 years ago
ugly ugly day again....but in a sane world this is 10x the mkt cap it is today
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saigai saigai 2 years ago
grinding our way to fair value.. whatever that is well north of here
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saigai saigai 2 years ago
hopefully we hold these gains
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StockLogistics StockLogistics 2 years ago
β€œ8:05a ET 10/3/2022 - Globe Newswire
Spero Therapeutics to Host Virtual R&D Event on Non-Tuberculous Mycobacterial Pulmonary Disease and the SPR720 Program

GlobeNewswireOctober 03, 2022
Event is taking place on Thursday, October 6th at 11:30 a.m. ET


Event will feature a presentation by key opinion leader, Kevin L. Winthrop, MD, MPH (Division of Infectious Disease, OHSU Medical School)

CAMBRIDGE, Mass., Oct. 03, 2022 (GLOBE NEWSWIRE) -- Spero Therapeutics, Inc. (Nasdaq: SPRO), a multi-asset clinical-stage biopharmaceutical company, focused on identifying, developing and commercializing treatments in high unmet need areas involving rare diseases and multi-drug resistant (MDR) bacterial infections, today announced that it will host a virtual R&D event on Thursday, October 6, 2022, at 11:30 a.m. Eastern Time.

The virtual event will feature a presentation by key opinion leader, Kevin L. Winthrop, MD, MPH, from the Division of Infectious Disease, OHSU Medical School. During his presentation, Dr. Winthrop will discuss the etiology, unmet medical need, and treatment landscape of non-tuberculous mycobacteria (NTM) pulmonary disease. Members of the Spero management team will provide an overview of the development program for SPR720, a potential novel first line oral therapy for NTM infections.

A live Q&A session will follow the formal presentations. To register for the event, please click here.

Dr. Winthrop Biography:

Kevin L. Winthrop, MD, MPH, Professor of Public Health, Infectious Diseases, and Ophthalmology at Oregon Health and Science University, is a former staff infectious disease epidemiologist from the U.S. Centers for Disease Control and Prevention's Division of Tuberculosis Elimination. He has co-authored over 300 publications, many detailing the epidemiologic and clinical aspects of nontuberculous mycobacterial diseases, tuberculosis, and other infections associated with rheumatic diseases and biologic immunosuppressive therapies. Clinically, he provides regional consultations for mycobacterial diseases and other chronic chest infections and serves as the medical consultant to the Oregon Public Health Division's TB control program. His Center for Infectious Disease Studies has served as the lead institution and coordinating center for multiple cohort studies and clinical trials. He has served as a primary or senior investigator in many of these clinical and epidemiologic studies, and frequently collaborates with the Pulmonary Department on studies related to bronchiectasis. He founded the NTM Research Consortium and associated Clinical Trials Network which facilitate collaborative, multi-site grants and clinical trials among patients with NTM. He is a member of the graduate faculty at OHSU where he mentors public health students, medical students, and physicians in post-graduate training.”
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saigai saigai 2 years ago
look out above...lets go friday
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StockLogistics StockLogistics 2 years ago
β€œIf Spero’s license with Meiji is terminated, or if Meiji forfeits or loses its rights to develop, manufacture and commercialize tebipenem HBr and products that contain tebipenem HBr in any countries in the Meiji Territory, then GSK will have an exclusive first right to negotiate with Spero to add any such countries to the GSK Territory.
Under the terms of the License Agreement, Spero will receive an upfront payment of $66 million for GSK to secure rights to the medicine. Remaining potential payments are milestone based, and are as follows:

Event Milestone payments (up to)
Delivery of phase III programme
$150m
Total commercial milestone payments based on first sale (US/EU)
$150m
Sales milestone events

Net sales greater than $200m
$25m
Net sales greater than $300m
$25m
Net sales greater than $400m
$25m
Net sales greater than $500m
$50m
Net sales greater than $750m
$50m
Net sales greater than $1,000m
$50m
Total sales milestone payments:
$225m
Royalties
Low-single digit to low-double digit (if
sales exceed $1bn) tiered royalties
on net product sales.
Royalties are subject to reduction in the event of third-party licenses, entry of a generic product or expiration of patent and regulatory exclusivity prior to the tenth (10th) anniversary of the first commercial sale of a GSK Licensed Product in a particular country.
Spero will be responsible for the execution and costs of the follow-up Phase III clinical trial of tebipenem HBr. GSK will be responsible for the execution and costs of additional further development, including Phase III regulatory filing and commercialization activities for tebipenem HBr in the balance of the GSK Territory outside of the United States. Spero will also be responsible for providing and paying for the clinical supply of tebipenem HBr while GSK will be responsible for the costs of the commercial supply of tebipenem HBr. A joint development committee will be established between GSK and Spero to coordinate and review development activities for tebipenem HBr in the United States.”
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saigai saigai 2 years ago
a few smart shorts see the writing on the wall..and nd it just takes time to consolidate through the profits through the shorting through the day flippers and the criminals..takes time
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saigai saigai 2 years ago
red to green when you least expect it
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SmokeSignals SmokeSignals 2 years ago
start loading for $5 imo
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