Halozyme Therapeutics Incorporated News - HALO

Your Hub for Real-Time streaming quotes, Ideas and Live Discussions

Premium

Halozyme to Participate at Upcoming Investor Conferences

Halozyme to Participate at Upcoming Investor Conferences PR Newswire SAN DIEGO, May 28, 2025 SAN DIEGO, May...

Halozyme Announces Bristol Myers Squibb Received European Commission Approval for Subcutaneous Opdivo® (nivolumab) Co-Formulated with ENHANZE® Across Multiple Solid Tumor Indications

Halozyme Announces Bristol Myers Squibb Received European Commission Approval for Subcutaneous Opdivo®...

Form 10-Q - Quarterly report [Sections 13 or 15(d)]

Form 8-K - Current report

HALOZYME RAISES 2025 FINANCIAL GUIDANCE RANGES AND REPORTS STRONG FIRST QUARTER 2025 RESULTS

HALOZYME RAISES 2025 FINANCIAL GUIDANCE RANGES AND REPORTS STRONG FIRST QUARTER 2025 RESULTS PR Newswire SAN...

Halozyme to Participate in the BofA Securities 2025 Healthcare Conference

Halozyme to Participate in the BofA Securities 2025 Healthcare Conference PR Newswire SAN DIEGO, May 5, 2025...

Form 4 - Statement of changes in beneficial ownership of securities

Form 8-K - Current report

Form 4 - Statement of changes in beneficial ownership of securities

Form SCHEDULE 13G/A - Statement of Beneficial Ownership by Certain Investors: [Amend]

Halozyme to Report First Quarter 2025 Financial and Operating Results

Halozyme to Report First Quarter 2025 Financial and Operating Results PR Newswire SAN DIEGO, April 28, 2025...

Halozyme Announces argenx Received Positive CHMP Opinion for VYVGART® (efgartigimod alfa) Subcutaneous Injection with ENHANZE® for Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Halozyme Announces argenx Received Positive CHMP Opinion for VYVGART® (efgartigimod alfa) Subcutaneous...

biotecholdguy 2 days ago

Every former & present employee of HALO, every stock holder, every person needing this miraculous subcutaneous solution to their medical health & dignity is praying for Halozyme Therapeutics to not have Merck steal away this intellectual property !

👍️ 1

biotechinvestor1 2 days ago

I'm buying every week

👍️0

biotecholdguy 2 days ago

The stock performance is because a LOT of investors are waiting to see if Merck (Goliath) gets away with STEALING
over 25 years of hard work from Halo (David).

👍️0

halofan 3 days ago

Today’s stock performance, in my non expert opinion, is attributed to short selling. Looking at the short position in HALO, the last reporting period shows a 1.2 million share increase in the short position. How dumb and stupid do you have to be to short this company?!!!

👍 2

biotechinvestor1 3 days ago

Let's for a moment, assume the worst possible scenarios:
1) Merck does not sign a licencing agreement for MDASE
2) Merck succeeds (very unlikely) to invalidate every single claim (about 20 in each patent) in all 13 patents that are in PGR's
3) Merck wins the infringement New Jersey court case (also unlikely)
4) CMS final guidelines does not recognize (unlikely) the significant clinical benefits (reduces side effects, improved efficacy, pt funstion, etc.) of ENHANZE
Even if all 4 of these unlikely scenarios take place, should a company with an EPS CAGR of +25% (far better than market and industry averages) and EBITDA margins growing 8% per year from 51% to 73%-75% (also better than market and industry averages) be trading at a PEG ratio of 0.3 and 2025 PE ratio of 10 when average S&P 500 and average biopharma is trading in PE ratios of mid 20's?
For the discerning investors, the answer is no. Anybody spending enough time to read quarterly reports knows that halozyme has given multi-year earnings projections that are based on Enhanze and does not include a dime of revenue from MDASE. So if halo win the MDASE battle with Merck, it would be icing on the cake but if Halo loses, it will not diminish their multi-year guidance by a dime.
Regarding CMS, if the decision goes against Halo, at worst, one or two of halo's partnered products may end up on the list of 15 CMS negotiated/discounted drugs. This means a 25% discount only on those 2 meds and only in the US. About half of Enhanze earnings come from outside US and will not be affected. So it would really be a 12.5% discount only.

👍️ 2

Fred Kadiddlehopper 4 days ago

I was confused by that as well.

👍️ 1

biotechinvestor1 4 days ago

Today Mark said "the first-filed PGR instituted for trial on March 2, 2026, with the decision to follow by June 2, 2026. That's really where the action is."
He was asked a follow-up question about multiple patents that are in dispute and under PGR potentially. He replied "we think that the issues of importance are going to be in this first trial. That's really where the action is going to be. That's really the thing to be paying attention to ...that's the next big event that we would like people to be paying attention to."
But on the May 6 earnings call, Helen said the PGRs were "a little bit of a sideshow and the most important one is actually the actual lawsuit that we filed. I'd keep your attention on that one."

Why the mixed messages?

👍️ 2

biotecholdguy 4 days ago

Thank you for all your work on these postings.

👍 2

biotechinvestor1 4 days ago

Helen at GS today (transcript):https://www.investing.com/news/transcripts/halozyme-at-goldman-sachs-conference-subcutaneous-innovation-drives-growth-93CH-4087223

👍️ 2

biotechinvestor1 4 days ago

During the last earnings call, CEO stated: “Obviously, the PGR we consider to be frankly a little bit of a sideshow. PGRs tend to be filed when companies are concerned that they are infringing and they seek to invalidate the patents. We feel very confident in our ability to prevail in those PGRs. And even if they were to win one or two of the PGRs because there are several in place, we do not believe that will have any impact at all on our infringement at case where we have multiple additional claims that are not subject to the PGR that are the basis of that infringement case. So, two very separate things. The most important one is actually the actual lawsuit that we filed. I’d keep your attention on that one.” https://www.stockinsights.ai/us/0001159036/earnings-transcript/fy25-q1-e012

👍️ 2

biotechinvestor1 4 days ago

Merck clearly knew they were infringing on Halozyme's patents. There is a good chance they (Merck) is now putting up a fight simply to get the best terms in a negotiated MDASE license with halo. They (Merck) were successful in getting the USPO to institute a review on one of Halozyme's patents. Although Merck will ultimately lose some (if not all) of the PGR's, this (the initiation of a review) is a small win for Merck. However, it will likely be all downhill from here for Merck's position. If they don't negotiate a deal with halo now, they will have to do so from a weaker position later, especially if New Jersey court puts a hold on SC Keytruda in an injuction.

👍️ 2

biotechinvestor1 4 days ago

Let's see what Helen has to say about Merck at Goldman Sachs at 10 am ET.

👍️ 1

Fred Kadiddlehopper 5 days ago

What's the Ackman Harvard story to do with HALO?

👍️ 1

Hero Car 6 days ago

The percentage of profitable recommendations made by Mohit Bansal is 50%, and the average return per transaction is 2.40%.

👍️ 1

CelestialSage6 6 days ago

i'm sorry... :(

https://news.bloomberglaw.com/health-law-and-business/halozyme-shares-dip-as-wells-fargo-flags-review-in-patent-case

https://www.gurufocus.com/news/2869932/harvard-on-fire-ackman-demands-entire-board-resign-in-explosive-showdown

👍️ 1

biotechinvestor1 6 days ago

You are forgetting that Merck would have to prevail in invalidating every single claim in every single PGR. For example in patent #600 (PGR 006) alone, there are about 21 claims in different categories. Claims 1-4, 8-10: Focus on the modified PH20 polypeptide itself, either as a base composition • Claims 11-13: Cover genetic tools (nucleic acid, vector, host cell) for producing the polypeptide. • Claims 14-18: Cover pharmaceutical compositions containing the polypeptide, alone or with other agents. • Claims 19-20: Describe methods of administering the compositions. • Claim 21: Describes a method of manufacturing the polypeptide. “If any of these remaining claims are upheld as patentable following the trial, the ’600 patent will remain valid with respect to those claims. Conversely, if all remaining claims are found unpatentable, the patent would be invalidated.” So for Merck to succeed they have to successfully invalidate every single claim (about 20 in each patent) in every single patent (the 13 they are trying to invalidate through 13 PGR filings), AND win the jury infringement trial (separate matter than PGR’s) for everyone of these 13patents plusthe additional 2 patents that they are not even disputing through PGR’s.
Odds are against Merck.

👍️ 2

CelestialSage6 6 days ago

pgr2025-00053 has been added. A total of 13 pgrs have been registered, 1 pgr has been initiated and will be initiated sequentially. Halozyme's breathing is getting tight.

👍️ 1

biotechinvestor1 1 week ago

"Btw, Merck is using the PTAB, a mechanism to review wrongly-granted patents, to challenge Halozyme’s patents. Ironically, PhRMA, where Merck is a long-standing member, is lobbying to pass the PREVAIL Act to gut that very mechanism."

👍️ 1

PaladinConqueror59 1 week ago

GO FOR IT!

👍️0

biotechinvestor1 1 week ago

Not all these PGR's are the same. For some (eg. 003, 004 and 009), Halozyme did not file a Discretionary Denial motion. But for others (eg. 006 and 017), Halozyme did.
Merck needs to win all of these PGR's. Halo needs only one to go its way.
https://portal.unifiedpatents.com/ptab/case/PGR2025-00006

👍️ 1

biotechinvestor1 1 week ago

That is the truth.

👍️ 1

biotecholdguy 1 week ago

Merck will lose this against HALO !
You can't steal the technology & prevail !!

👍️ 2

Howeeme 1 week ago

Sold out. Paid a great dividend and got a great price. Look up refac technologies inc. Eugene lang was the ceo and chairman. Long time ago.

👍️ 2

GreedyG1 1 week ago

Because there’s an underlying lack of confidence in the company’s long term growth.

👍️ 1

halofan 1 week ago

I don’t understand—just because the Patent Office has agreed to review a claim, why does that weaken HALO’s patent? Is it possible that HALO’s patent is strong and that they will prevail? Another analyst reaching speculative conclusions.

👍️0

Minninv 1 week ago

Wells Fargo analyst Mohit Bansal notes that PTAB has instituted Merck’s (MRK) patent grant review against Halozyme Therapeutics (HALO) MDASE patents. This patent is one of the patents Merck is fighting against Halozyme. The firm believes this likely reduces the probability of Halozyme prevailing in this case and weakens the bull argument. Wells has an Equal Weight on Halozyme with a price target of $65 on the shares.

👍️ 1

GreedyG1 1 week ago

What happened to them? I don’t see a ticker for them.

👍️0

Howeeme 1 week ago

Years ago I owned stock in a company called Refac. All they did was own license and protect patents. Did very well. The fact that Mdase has no sales is not relevant.

👍️ 2

Fred Kadiddlehopper 1 week ago

Nobody has signed a single deal involving Mdase.

👍️0

biotechinvestor1 1 week ago

Correction: PGR 003 (not 006)

👍️0

biotechinvestor1 1 week ago

One more reason (not mentioned in my previous post) why odds favor Halozyme's sucsess in the patent dispute: Merck would have to prevail in invalidating every single claim in every single PGR. For example in patent #600 (PGR 006) alone, there are about 21 claims in different categories. Claims 1-4, 8-10: Focus on the modified PH20 polypeptide itself, either as a base composition • Claims 11-13: Cover genetic tools (nucleic acid, vector, host cell) for producing the polypeptide. • Claims 14-18: Cover pharmaceutical compositions containing the polypeptide, alone or with other agents. • Claims 19-20: Describe methods of administering the compositions. • Claim 21: Describes a method of manufacturing the polypeptide.
“If any of these remaining claims are upheld as patentable following the trial, the ’600 patent will remain valid with respect to those claims. Conversely, if all remaining claims are found unpatentable, the patent would be invalidated.” So for Merck to succeed they have to successfully invalidate every single claim (about 20 in each patent) in every single patent (the 12 they are trying to invalidate through 12 PGR filings), AND win the jury infringement trial (separate matter than PGR’s) for everyone of these 12 patents plus the additional 3 patents that they are not even disputing through PGR’s.

👍️ 3

maumar 1 week ago

XBI up 1,3%, HALO down 4,1%, Alteogen up 8,8% today. Clearly, the market doesn’t think we got good news yesterday.

👍️ 2

GreedyG1 1 week ago

…or tank on any bad news. This stock is highly sensitive. Any negative patent news or new rival tech in advanced stages would put this somewhere in the 40’s. And why hasn’t there been a significant new deal in the last couple of years when the CEO keeps telling us they’ve been in talks that whole time? They need either a new major partnership or something innovative. Without either of those, this stock is a ticking time bomb.

👍️ 3

biotechinvestor1 1 week ago

I bought more today too

👍️0

NoobyDoo 1 week ago

Added more trading shares today. They will be ready to jettison between $68-$75+ based on news, partnerships, deals etc. Probably by next earnings call we should hear of something tangible lol! GLTA

👍 1 👍️ 1

biotechinvestor1 1 week ago

Halozyme’s officers and directors, if you so not have enough confidence to personally buy shares at a PEG ratio of 0.3 and 2025 PE ratio of 11, you should step down and let others lead. It is absolutely absurd for a company withEPS CAGR of +25% and EBITDA margins growing 8% per year from 51% to 73%-75% to be trading at such ridiculously low valuations. Do your jobs or step down.

👍️ 1

biotechinvestor1 1 week ago

See page 19 on Nanoform's presentation (link below). They have the one pill (oral) in clinical trials. Their subcutaneous technology has not even finished preclinical (animal trials) yet. Then they will have to do phase 1-3 trials in humans. It willl be 7-10 years before they have anything subcutaneous on the market (that is if they find a partner who would fund the trials). They are hoping to find a partner in 2026-2027 to fund the clinical trials. Then you are looking ag another 5-7 years.
They are not a threat for several years but should stay on halo's management radar. If clinical trials are looking good, maybe Halo should buy them out.
https://nanoform.com/en/wp-content/uploads/sites/2/2025/05/Nanoform-Management-Presentation-Q1-2025-Report.pdf

👍️ 1

MysticalGladiator72 1 week ago

Time to buy more.
The losers have come out on a bad trading day.
They will be eating crow in the near future.

👍 1

CelestialSage6 1 week ago

One of the 12 has been started and will proceed gradually. As a result, the mdase patent will be invalidated and the patent dispute lawsuit of Halozyme will be dismissed. Because the infringed patent itself will disappear. lolololololololo

👍️ 1

CelestialSage6 1 week ago

Oh my god! Halozyme's breathing is getting tighter and tighter!

👍️ 1

biotechinvestor1 1 week ago

"Obviously, the PGR, we consider to be, frankly, a little bit of a sideshow. PGRs tend to be filed when companies are concerned that they are infringing and they seek to invalidate the patents. We feel very confident in our ability to prevail in those PGRs.
And even if they were to win 1 or 2 of the PGRs because there are several [7] in place, we do not believe that will have any impact at all on our infringement case where we have multiple additional claims that are not subject to the PGR that are the basis of that infringement case, so two very separate things. The most important one is actually the actual lawsuit that we filed. l'd keep your attention on that one."

👍️0

GreedyG1 1 week ago

I’m losing confidence in Halozyme. It’s a one trick pony that can’t make new deals. Very fragile. I should have sold off a bunch more at $70.

👍️ 1

stockrafter 1 week ago

To little, to late, to slow to attack. Try making some dang deals!!!

👍️ 2

stockrafter 1 week ago

"This innovation marks a significant step forward in patient-centric care, enabling a simple, hyaluronidase-free subcutaneous injection of a full dose in a single 2mL syringe,” said Prof. Edward Hæggström, CEO of Nanoform. "

This is going to hurt, IMO.

"DEVELOPMENT OF NANOFORMED TRASTUZUMAB FOR SUBCUTANEOUS INJECTION TO BE PRESENTED AT DDF SUMMIT IN BERLIN "

https://storage.mfn.se/bb1a1c0e-aea9-4d00-bfa3-2f09d3bdb954/development-of-nanoformed-trastuzumab-for-subcutaneous-injection-to-be-presented-at-ddf-summit-in-berlin.pdf

👍️ 1

biotechinvestor1 1 week ago

Merck is infringing on 15 of Halozyme's MDASE patents. Merck has asked US Patent trial and Apeal Board (UPTAB) to invalidate 12 of these 15 patents. UPTAB started the review process on one these patents (Patent 11,952,600, PGR2025-00003) yesterday. A decision will be made after April 2026 per UPTAB document released yesterday.
For Merck to succeed, it needs to win all of the 12 invalidation cases and still win the NJ Federal Distrist Court infringement case (separate jury trial than the UPTAB review). Unlike Merck, for Halozyme to succeed, it only needs to a) win one of the UPTAB reviews, or b) win the jury trial, or c) have Merck sign a licensing deal. Not only halozyme has the more compelling legal arguments but also unlike Merck, halo has multiple paths to succeed.

👍️0

stockrafter 2 weeks ago

"A phase I clinical study to evaluate rapid, high-volume, subcutaneous auto-injector tolerability with recombinant human hyaluronidas"

They keep trying, from preclinical testing to running their own Phase 1 trial. Info looks good and again, Takeda IgG was used.

"The test solution was composed of 10% (100 mg/mL) IgG solution (GAMMAGARD LIQUID [32], Baxalta Inc., a Takeda Company, Lexington, MA, USA) co-administered with 4000 U/mL rHuPH20. The viscosity of the IgG solution was 3.4 cP."

One of these days......a HVAI deal......

👍️ 3

biotechinvestor1 2 weeks ago

From James ST:
"$HALO Buy Case: – Just posted strong results, crushing estimates, raised guidance, tons of cash flow. – New $250M share repurchase. Stock went up 35% in Q1 during previous $250M buyback. – CEO says recent stock drop "reaction was way overblown, misunderstood... reports had erroneous information in them... a massive overreaction." – HALO has raised guidance 4X in the past year (6/6/24, 10/31/24, 1/8/25, 5/6/25). – Just boosted 2025 EPS guidance up to $5.30-$5.70. Single-digit P/E. – Increased 2027 EPS guidance to $8.00-$8.60. 2023-2028 EPS growth rate: 25%. – Huge potential upside with lawsuit against Merck over 15 HALO patents: "a mid-single-digit royalty on a product that sells $30,000,000,000/year." – HALO CEO: Yesterday's subcutaneous Opdivo approval "is just one of the 11 growth catalysts for our commercialized SC products expected this year." – "Long-term growth prospects have never been better.""

👍️ 3

biotechinvestor1 2 weeks ago

HC Wainwright & Co. Reiterates Buy on Halozyme Therapeutics, Maintains $72 Price Target 7:13 AM EDT, May 29, 2025 HC Wainwright & Co. analyst Mitchell Kapoor reiterates Halozyme Therapeutics (NASDAQ:HALO) with a Buy and maintains $72 price target.

👍️ 1

CelestialSage6 2 weeks ago

The MDase patent invalidation trial will begin soon. I am very interested.

👍️0

biotechinvestor1 2 weeks ago

SAN DIEGO, May 28, 2025 /PRNewswire/ --Halozyme Therapeutics, Inc. (NASDAQ: HALO)
("Halozyme") today announced that Dr. Helen Torley, president and chief executive officer, is scheduled to participate and host investor meetings at the following investor conferences.
Details on the Company's participation are as follows:
Event:
House Call Virtual
Benchmark 2025 Healthcare
Format:
Date:
Conference
1x1 Meetings
Thursday, May 29, 2025
Event:
Global Healthcare
Goldman Sachs 46th Annual
Format:
Date:
Conference 2025
Presentation Time:Fireside Chat and 1x1 Meetings
Monday, June 9, 2025 7:00am PT / 10:00am ET

👍️ 1

Market Data

News

Trading Tools

Markets

Discover

Hot Features

Follow Feed

Options Flow

Monitor

Halozyme Therapeutics Incorporated (HALO)

Your Hub for Real-Time streaming quotes, Ideas and Live Discussions

HALO News

Halozyme to Participate at Upcoming Investor Conferences

Halozyme Announces Bristol Myers Squibb Received European Commission Approval for Subcutaneous Opdivo® (nivolumab) Co-Formulated with ENHANZE® Across Multiple Solid Tumor Indications

Form 10-Q - Quarterly report [Sections 13 or 15(d)]

Form 8-K - Current report

HALOZYME RAISES 2025 FINANCIAL GUIDANCE RANGES AND REPORTS STRONG FIRST QUARTER 2025 RESULTS

Halozyme to Participate in the BofA Securities 2025 Healthcare Conference

Form 4 - Statement of changes in beneficial ownership of securities

Form 4 - Statement of changes in beneficial ownership of securities

Form 8-K - Current report

Form 4 - Statement of changes in beneficial ownership of securities

Form 4 - Statement of changes in beneficial ownership of securities

Form 4 - Statement of changes in beneficial ownership of securities

Form SCHEDULE 13G/A - Statement of Beneficial Ownership by Certain Investors: [Amend]

Halozyme to Report First Quarter 2025 Financial and Operating Results

Halozyme Announces argenx Received Positive CHMP Opinion for VYVGART® (efgartigimod alfa) Subcutaneous Injection with ENHANZE® for Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

HALO Discussion

Your Recent History

Company

Business

Popular

Get The App

Trending Now

Toplists

Market Data

News

Trading Tools

Markets

Discover

Hot Features

Follow Feed

Options Flow

Monitor

Halozyme Therapeutics Incorporated (HALO) News

Halozyme Therapeutics Incorporated (HALO)

Your Hub for Real-Time streaming quotes, Ideas and Live Discussions

HALO News

Halozyme to Participate at Upcoming Investor Conferences

Halozyme Announces Bristol Myers Squibb Received European Commission Approval for Subcutaneous Opdivo® (nivolumab) Co-Formulated with ENHANZE® Across Multiple Solid Tumor Indications

Form 10-Q - Quarterly report [Sections 13 or 15(d)]

Form 8-K - Current report

HALOZYME RAISES 2025 FINANCIAL GUIDANCE RANGES AND REPORTS STRONG FIRST QUARTER 2025 RESULTS

Halozyme to Participate in the BofA Securities 2025 Healthcare Conference

Form 4 - Statement of changes in beneficial ownership of securities

Form 4 - Statement of changes in beneficial ownership of securities

Form 8-K - Current report

Form 4 - Statement of changes in beneficial ownership of securities

Form 4 - Statement of changes in beneficial ownership of securities

Form 4 - Statement of changes in beneficial ownership of securities

Form SCHEDULE 13G/A - Statement of Beneficial Ownership by Certain Investors: [Amend]

Halozyme to Report First Quarter 2025 Financial and Operating Results

Halozyme Announces argenx Received Positive CHMP Opinion for VYVGART® (efgartigimod alfa) Subcutaneous Injection with ENHANZE® for Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

HALO Discussion

Your Recent History

Company

Business

Popular

Get The App

Sign in

Go Ad-Free