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| Holder | Type | Held (Actual) | % of Outstanding | Market Value | Date Reported |
|---|---|---|---|---|---|
| Wellington Management Group LLP | Institution | 11,982,283 | 13.89% | US$ 393.50M | 2026-03-31 |
| Bain Capital Life Sciences Investors, LLC | Institution | 8,448,158 | 9.80% | US$ 277.44M | 2026-04-30 |
| KKR & Co. Inc. | Institution | 5,474,931 | 6.35% | US$ 179.80M | 2026-04-24 |
| FMR LLC | Institution | 5,396,363 | 6.26% | US$ 177.22M | 2026-03-31 |
| Baron Capital Group, Inc. | Institution | 3,827,531 | 4.44% | US$ 125.70M | 2026-03-31 |
| Mr. Lonnie Smith | Insider | 3,474,304 | 4.03% | US$ 114.10M | 2025-08-08 |
| Hadley Harbor Master Investors (Cayman) II L.P. | Institution | 3,388,522 | 3.93% | US$ 111.28M | 2025-08-08 |
| U.S. Venture Partners X, L.P. | Institution | 3,171,062 | 3.68% | US$ 104.14M | 2026-04-24 |
| USVP Management Company, LLC | Institution | 3,171,062 | 3.68% | US$ 104.14M | 2026-04-24 |
| Martis Capital Management, LLC | Institution | 2,243,532 | 2.60% | US$ 73.68M | 2025-08-08 |
| Janus Henderson Group plc | Institution | 2,180,976 | 2.53% | US$ 71.62M | 2026-03-31 |
| HealthCor Management L.P. | Institution | 2,082,014 | 2.41% | US$ 68.37M | 2026-03-31 |
| Vanguard Portfolio Management, LLC | Institution | 2,045,938 | 2.37% | US$ 67.19M | 2026-03-31 |
| Invesco Ltd. | Institution | 1,912,288 | 2.22% | US$ 62.80M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 1,893,495 | 2.20% | US$ 62.18M | 2026-03-31 |
| UBS Asset Management AG | Institution | 1,843,912 | 2.14% | US$ 60.55M | 2026-03-31 |
| BlackRock, Inc. | Institution | 1,462,584 | 1.70% | US$ 48.03M | 2026-03-31 |
| British Columbia Investment Management Corporation | Institution | 1,367,960 | 1.59% | US$ 44.92M | 2026-04-24 |
| HealthCor Partners Fund, L.P. | Institution | 1,248,939 | 1.45% | US$ 41.02M | 2026-03-24 |
| AllianceBernstein L.P. | Institution | 1,224,326 | 1.42% | US$ 40.21M | 2026-03-31 |
| Millennium Management LLC | Institution | 1,093,417 | 1.27% | US$ 35.91M | 2026-03-31 |
| Baillie Gifford & Co. | Institution | 1,084,652 | 1.26% | US$ 35.62M | 2026-03-31 |
| Dr. Charles Taylor | Insider | 952,907 | 1.10% | US$ 31.29M | 2025-08-08 |
| Summit Partners Public Asset Management, LLC | Institution | 892,093 | 1.03% | US$ 29.30M | 2026-03-31 |
| HealthCor Partners Fund II LP | Institution | 833,075 | 0.97% | US$ 27.36M | 2026-03-24 |
| Franklin Resources, Inc. | Institution | 793,721 | 0.92% | US$ 26.07M | 2026-03-31 |
| Eventide Asset Management, LLC | Institution | 756,956 | 0.88% | US$ 24.86M | 2026-03-31 |
| Citadel Advisors LLC | Institution | 756,605 | 0.88% | US$ 24.85M | 2026-03-31 |
| Eaton Vance Management | Institution | 737,170 | 0.85% | US$ 24.21M | 2026-03-31 |
| Voya Investment Management LLC | Institution | 727,667 | 0.84% | US$ 23.90M | 2026-03-31 |
| Ensign Peak Advisors, Inc. | Institution | 690,466 | 0.80% | US$ 22.67M | 2026-03-31 |
| Next Century Growth Investors LLC | Institution | 652,969 | 0.76% | US$ 21.44M | 2026-03-31 |
| 12 West Capital Management LP | Institution | 640,000 | 0.74% | US$ 21.02M | 2026-03-31 |
| Fred Alger Management, LLC | Institution | 638,306 | 0.74% | US$ 20.96M | 2026-03-31 |
| Rock Springs Capital Management LP | Institution | 572,500 | 0.66% | US$ 18.80M | 2026-03-31 |
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