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Amarin Corp PLC

Amarin Corp PLC (AMRN)

0.5828
0.0028
(0.48%)
Closed October 10 3:00PM
0.5752
-0.0076
(-1.30%)
After Hours: 6:38PM

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AMRN News

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AMRN Discussion

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Tatsumaki Tatsumaki 1 hour ago
And definitely not before we need to get the SP above a buck.
Who says this ticker has to stay listed?
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Number sleven Number sleven 2 hours ago
JRoon, If you wouldn't mind, explain your position in detail. I only ask because you stated it as an an absolute.
Sleven,
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rosemountbomber rosemountbomber 2 hours ago
I did that on two previous occasions thinking that the stock price was at a low point. Needless to say those didn’t work out very well for me, but to be fair, we only have 60 cents more to lose so you are probably right.
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Jasbg Jasbg 3 hours ago
As I said earlier - Amarin has cost me the value of now 6 new Tesla 3 electric cars !

Actually the KM period is what I blame myself the most !

PS were at $ 6.63 - when he took over - but has fallen like a rock ever since.
-------------------------------------

Will we recover (partly / with profit) from this - that is as uncertain as who will be new President in US :)
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JRoon71 JRoon71 3 hours ago
Seve, you need a drink
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seve333 seve333 4 hours ago
If they do a reverse split they may as may fold up shop. A reverse split is nothing more than an invitation to shorts to destroy what little value is left in a stock price. And I mean unless denner is shorting the crap out of this his shares would also take a tremendous hit in a reverse split. I doubt the company would ever recover form it as most do not. Why would you do a reverse split on a 100 milllion dollar investement when you could actually do a buyback instead? The buyback is probably all they got to get it over a buck because the non usa sales are moving far too slow to make a difference. I dont recall when they have until but I thought it was May. If they cannot get it over a buck jn 7 moths then they are really really bad at this.
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xblkbk xblkbk 5 hours ago
No.
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JRoon71 JRoon71 5 hours ago
For anyone with significant AMRN shares in their IRA, now would be an ideal time to do a Roth conversion on those shares.
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JRoon71 JRoon71 6 hours ago
Shado, there is nothing from a legal perspective that is going to change anything in the next few years. And definitely not before we need to get the SP above a buck.
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Number sleven Number sleven 6 hours ago
Shadolane, What's the time frame?
Sleven,
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shadolane shadolane 6 hours ago
Unless something significant happens in the litigation arena a reverse split may be the only way to salvage the pps from a compliance perspective within the time frame that Amarin has.

I doubt sales in other markets or studies for other uses will intervene in the near term.

We've encountered significant negative effects since the largest one......the Du decision.

And some of us may not be able to survive long enough to see how this all turns out.

IMO
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Nukemtiltheyglow Nukemtiltheyglow 7 hours ago
xblkbk, are you of retirement age?
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JRoon71 JRoon71 8 hours ago
Wow! As a follow up to this post:
---------------------------------------------------------------------------

I just checked and it shows $98.40 for 30 day supply.

One thing that is frustrating is when I put “Vascepa” in the search bar, it comes back with:
Vascepa (generic)
Vascepa (brand-name)
icosapent ethyl (generic Vascepa)

---------------------------------------------------------------

I later saw that this came up when I selected Vascepa (generic):


So basically, when I selected "generic Vascepa", a pop-up box came up and told me that I could find BRANDED Vascepa for cheaper.

But then I also saw this description under generic Vascepa:
About generic Vascepa
Vascepa (icosapent ethyl) is used to reduce cardiovascular risk and treat high triglyceride levels.
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JRoon71 JRoon71 9 hours ago
I just checked and it shows $98.40 for 30 day supply.

One thing that is frustrating is when I put “Vascepa” in the search bar, it comes back with:
Vascepa (generic)
Vascepa (brand-name)
icosapent ethyl (generic Vascepa)

Exactly as typed, and in that order
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rosemountbomber rosemountbomber 9 hours ago
North, I wonder if it is possible that this discounted price on GoodRx has only been put into effect very recently and was not in effect 30 days ago.
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north40000 north40000 10 hours ago
That exclusive “discount” did not work or was “not available” when I refilled a 90 day brand Vascepa prescription at CVS a month ago, as previously reported. We will try again in another supply 2 months at the same or different pharmacy. Thanks for the news.

That suit filed by Express Scripts and CVS/Caremark against FTC in Missouri is meritless as far as I’m concerned. My usual co-pay cost of $9 or $15 for a 3- month Vascepa supply had disappeared as of 7/01, replaced by over a $1000 cash payment even with a GoodRX coupon.
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Birdbrain Ideas Birdbrain Ideas 11 hours ago
That's great news. Makes sense that Amarin probably will be in better position to adjust U.S. prices once it is finished negotiating most of its deals in Europe.
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Meowza Meowza 11 hours ago
Europe worth more than Italy, France and Germany combined 🙃
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Meowza Meowza 11 hours ago
We have already been creamed under denner That does sound like him
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mrmainstreet mrmainstreet 12 hours ago
Interesting. I use GoodRx all the time and it's legit.
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seve333 seve333 12 hours ago
I remember how hyped up Brave was on here a year ago and hyped for a long time. I never understood the hype people were acting like it was going to be huge and drive the stock to 50 bucks. Some said Denner knew what he had in Brave. I think it is safe to say at this point Denner doesn't and never had any secret weapon or master plan. He is doing the exact same thing the old management did to a T. I guess maybe he is a little better at controlling costs but other than that there are no differences that I see. It makes you wonder what the point of the nasty proxy battle even was for especially given we get even less communication from denner.
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JRoon71 JRoon71 13 hours ago
Noticed that as well. Again, this is why we need RW data. Man, I wish MITIGATE gave us something.
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CaptBeer CaptBeer 13 hours ago
With all the talk about IPE and an AFib adverse side effect, I found it interesting that in this study there were 2 AFib events, both of which occurred in the placebo arm.
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JRoon71 JRoon71 13 hours ago
Monk, what are you asking? There was essentially no difference between Vascepa and placebo. In fact, the placebo group actually did slightly better (which was not statistically significant).

IMO, the trial is too short, and I'm not even sure the outcome measures were appropriate. But in a short trial like this, it's all they could really measure.

As CaptBeer stated, I believe that EPA is effective over long periods of time, which is why populations with high fish intake have lower incidence of dementia. Vascepa is not an acute medication.

But outside of meta-analysis, I don't believe a long-term trial could ever be conducted like this. It would have to be VERY long, and it would have to start earlier in life.
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JRoon71 JRoon71 13 hours ago
Monk, couple things:

1. The report is not "final". The NLM does a review process on the submission, with comments. But they are required to publicly post the submission within 30 days of original submission, even if all questions have not yet been answered. You can see their comments in the results tab. So, nobody would likely "announce" results until the submission was "final".

2. This is not Amarin's study. So since the results didn't say anything positive, Amarin has zero reason to PR this. Same with U of Wisc. No need to make a major announcement.

3. The results are not "buried". They are displayed exactly how the NLM requires it to be displayed. They have a standard format that all trials follow.
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CaptBeer CaptBeer 13 hours ago
the differences between V and the placebo were not significant. That’s not to say that IPE isn’t beneficial in the long run ( really long, like 10 years), but it does say that no one will be doing a study like that any time soon. I’ve been on VASCEPA for 10 years now and I’m still doing fine.
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DMC8 DMC8 14 hours ago
https://clinicaltrials.gov/study/NCT02719327?tab=history&a=17#version-content-panel
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Monk4444 Monk4444 1 day ago
Capt. B.
Your thoughts on this report from Jroon that Brave was a bust???
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Monk4444 Monk4444 1 day ago
Rose, Roon
Something does not seem right here.
Why do you have to dig for the results?
I thought this would be more of an "announcement"
than a technical piece with results buried??
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rosemountbomber rosemountbomber 1 day ago
Thanks for posting. Good to know. Of course those with insurance would still pay less than that for GV.
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xblkbk xblkbk 1 day ago
BbI,

Don’t know if this has already been posted, but GoodRx is saying switch from generic V to brand V for less money!!!

Per their “exclusive manufacturer discount”:

30 day, branded V, retailing for $406.65, is $98.40 with GoodRx

90 day, retailing for $1216, is $295.20 with GoodRx

I know management had talked in the past about the problem that an USA authorized generic’s pricing would disadvantage reimbursement negotiations in the EU. So maybe this “exclusive discount” is a backdoor for the near term??

My script is up for renewal in a few days. Since I’m stuck on Obamacare, where V isn’t covered, I’ve been paying $680 for a 90 day supply with the current Amarin discount. Will use the GoodRx codes and see if they work!!!



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rosemountbomber rosemountbomber 1 day ago
You have to expand those results sections to see it.
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north40000 north40000 1 day ago
Meantime, take a look at bfiest’s latest message on the CDMO ticker symbol, and the Biosecure Act summary discussion there. If that bill passes the Senate and is signed into law, Medicare ability, VA hospital ability to contract with foreign jurisdiction producers of meds/drugs may be affected. What effect on Hikma, Dr.Reddy et al? Do they already produce their generic for Vascepa in the United States, or do they import from abroad…..?
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Monk4444 Monk4444 1 day ago
JR
Could not find any of this verbiage.
"The average ASL at 18 months for the IPE group was slightly lower than the placebo group, but this difference did not reach significance.

On average, there was a slight increase in pTau181 in CSF after 18 months of IPE compared to placebo after controlling for age at baseline Visit and pTau181."



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north40000 north40000 1 day ago
Thanks for summary. I’ll try what you suggest……just back from workout with physical trainer.
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seve333 seve333 1 day ago
Yep but pretty concerning when denner could have had berg the whole time he picked his own guy who did not even last a year. I know denner was really hyped up but I have seen nothing to impress me about him. I remember when they said denner would never ever let the stock drop below a buck and was going to sell this for 15 a share. Now here we are. I would say it cant get any worse but it always can with AMRN. The biggest issue is nobody even knows what denners plan is he has never said a word.
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rosemountbomber rosemountbomber 1 day ago
Unfortunately I am not as confident. What I can’t understand is how someone who should know his way around the stock market could possible authorize or pursue a RS, if indeed that is what actually happens. A RS split is not negative only when a company has positive and growing earnings. Otherwise the loss per share gets magnified and the market drives the stock price back from whence it came prior to RS.

But I appreciate your post as it gives me a glimmer of hope that the nonsense of a RS is not undertaken.
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Birdbrain Ideas Birdbrain Ideas 1 day ago
You raise a very good counterpoint suggestion to my doom-and-gloom fear that they're going to announced a reverse split. The Investors Day event would make sense if they announce on earnings day at the end of the month that they are switching Vascepa to a generic in the U.S. I imagine they waited one quarter to see exactly how much their revenue dropped with the loss of that deal that brought us 25 percent of our revenues. If the loss on the quarter was substantial, it would make sense that they'd switch to a generic and say at earnings time that they're staging an Investor Day in a few weeks to better educate investors on what this will mean for Amarin going forward.

Actually, as I was writing the above, I was thinking that this is a more likely purpose for the Investor Day than my Doom and Gloom scenario.
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rosemountbomber rosemountbomber 1 day ago
I think price-wise we can (I believe successful AGs can still command a slightly higher price than Generics) but since the Generics have so many products and connections with the pharmacies, that I have always thought it would be tough slough.

It is the CVS Caremark decision that makes me wonder if an AG might make sense. Let me explain. CVS Caremark has stopped brand on the formulary (commercial) but although I could be wrong I believe they cover GV no matter the manufacturer. So they would automatically cover an AG. Willing yo stand corrected on this.
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JRoon71 JRoon71 1 day ago
Not real easy to copy and paste from this. Go to the link, scroll all the way down to Outcome Measures. Need to expand each Statistical Analysis section.

Tau and Beta Amyloid were slightly higher in the Treatment (Vascepa) Arm.

Cognitive Performance was slightly worse in Treatment (Vascepa) Arm (.455 vs. .611).

Cerebral Blood Flow was almost the same in both. Slightly higher in Treatment (Vascepa) Arm.
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north40000 north40000 1 day ago
Can you copy that portion of your link that discusses failure, and paste that discussion here? Today is 10/09…..that much I see, as well as an NIH comment that yields nothing on attempts to click.
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JRoon71 JRoon71 1 day ago
I posted the link. Not sure what else to tell you. Did the link not work?
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north40000 north40000 1 day ago
Where is your link to BRAVE trial failure? I see no evidence of failure from the link you posted a few hours earlier today.
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W0lf1 W0lf1 1 day ago
RMB, thank you for your reply. Can we compete with the generics by offering generic versions of Vascepa?
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rosemountbomber rosemountbomber 1 day ago
Many times I am obviously too dumb to think of or anticipate developments with this stock but if I had to come up with something I would say this.

Here in the US there would have to be some legal victories, or possibly the introduction of an AG. Could there be some deal or arrangement with a statin mfr to market a combo?

Outside of the US it seems more reimbursement approvals and an acceleration of scripts in ROW would be a welcome positive.
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KnowNothingJonSnow KnowNothingJonSnow 1 day ago
I’m old enough to remember when we had $700m in cash not all that long ago. Seems to be dwindling fast.
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JRoon71 JRoon71 1 day ago
BB, it was a biomarker study, so age shouldn’t have mattered much ( other than possibly the cognitive assessment).

But EPA is not an acute medication. It’s quite possible that over long periods of time, it can prevent buildup of tau and BA, to a degree.

This is why populations with high fish intake have lower incidence of Dementia.
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Birdbrain Ideas Birdbrain Ideas 1 day ago
I agree completely. The parameters of the trial seemed off base as well. I guess they kept extending the end date of the trial hoping something would show up. When I saw the age of the participants, I was thinking it was catching them too early for much of anything to show up unless you're dealing with someone with early onset of symptoms.
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W0lf1 W0lf1 1 day ago
Are there scenarios that would realistically lead to a favorable outcome?
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Number sleven Number sleven 1 day ago
RMB, If Amarin were marketing Vascepa in China on their own I might share your concerns. Our partner, a Chinese company, is selling the product. The Chinese government has certain self serving motivations to defend that company.
Sleven,
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