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| Holder | Type | Held (Actual) | % of Outstanding | Market Value | Date Reported |
|---|---|---|---|---|---|
| Dr. Matthew Angel | Insider | 4,837,070 | 33.72% | US$ 6.14M | 2026-03-24 |
| Sabby Volatility Warrant Master Fund, Ltd. | Institution | 492,223 | 3.43% | US$ 625.12k | 2025-12-31 |
| Versant Venture Management, LLC | Institution | 269,772 | 1.88% | US$ 342.61k | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 233,888 | 1.63% | US$ 297.04k | 2026-03-31 |
| Factor Bioscience Inc. | Institution | 231,482 | 1.61% | US$ 293.98k | 2026-03-24 |
| Versant Vantage II, L.P. | Institution | 162,972 | 1.14% | US$ 206.97k | 2026-03-30 |
| Versant Venture Capital IV, L.P. | Institution | 90,084 | 0.63% | US$ 114.41k | 2026-03-30 |
| Geode Capital Management, LLC | Institution | 86,990 | 0.61% | US$ 110.48k | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 68,908 | 0.48% | US$ 87.51k | 2026-03-31 |
| BlackRock, Inc. | Institution | 39,068 | 0.27% | US$ 49.62k | 2026-03-31 |
| Impresa Management LLC | Institution | 33,225 | 0.23% | US$ 42.20k | 2026-03-31 |
| Sabby Management, LLC | Institution | 17,856 | 0.12% | US$ 22.68k | 2026-03-31 |
| Versant Venture Capital VI | Institution | 16,149 | 0.11% | US$ 20.51k | 2026-03-30 |
| Northern Trust Global Investments | Institution | 14,053 | 0.10% | US$ 17.85k | 2026-03-31 |
| Dimensional Fund Advisors LP | Institution | 11,444 | 0.08% | US$ 14.53k | 2026-03-31 |
| UBS Asset Management AG | Institution | 4,533 | 0.03% | US$ 5.76k | 2026-03-31 |
| Mr. Stephen Brady | Insider | 3,613 | 0.03% | US$ 4.59k | 2025-11-18 |
| Tower Research Capital Europe Limited | Institution | 2,790 | 0.02% | US$ 3.54k | 2026-03-31 |
| Morgan Stanley | Institution | 2,058 | 0.01% | US$ 2.61k | 2026-03-31 |
| Osaic Wealth, Inc. | Institution | 1,529 | 0.01% | US$ 1.94k | 2026-03-31 |
| Dr. Geoffrey Nichol | Insider | 666 | 0.00% | US$ 845.82 | 2025-11-18 |
| Mr. Nicholas Maestas | Insider | 590 | 0.00% | US$ 749.30 | 2025-11-18 |
| Versant Side Fund IV, L.P. | Institution | 567 | 0.00% | US$ 720.09 | 2026-03-30 |
| Fédération des caisses Desjardins du Québec | Institution | 292 | 0.00% | US$ 370.84 | 2026-03-31 |
| Edward Jones Trust Company | Institution | 239 | 0.00% | US$ 303.53 | 2026-03-31 |
| Vanguard Global Advisers, LLC | Institution | 168 | 0.00% | US$ 213.36 | 2026-03-31 |
| SBI Holdings, Inc. | Institution | 56 | 0.00% | US$ 71.12 | 2026-03-31 |
| Royal Bank of Canada | Institution | 27 | 0.00% | US$ 34.29 | 2026-03-31 |
| Parallel Advisors, LLC | Institution | 18 | 0.00% | US$ 22.86 | 2026-03-31 |
| Citigroup Inc. | Institution | 8 | 0.00% | US$ 10.16 | 2026-03-31 |
| JPMorgan Chase & Co. | Institution | 5 | 0.00% | US$ 6.35 | 2026-03-31 |
| BNP Paribas Financial Markets SNC | Institution | 3 | 0.00% | US$ 3.81 | 2026-03-31 |
| Mr. Michael Raab | Insider | 0 | 0.00% | - | 2025-11-18 |
| Ms. Christine Pellizzari | Insider | 0 | 0.00% | - | 2025-11-18 |
| Dr. Ronit Simantov | Insider | 0 | 0.00% | - | 2025-11-18 |
| Dr. Samuel Whiting | Insider | 0 | 0.00% | - | 2025-11-18 |
| The Vanguard Group, Inc. | Institution | 0 | 0.00% | - | 2026-01-01 |
| CIBC Private Wealth Advisors, Inc. | Institution | 0 | 0.00% | - | 2026-03-31 |
| DRW Holdings, LLC | Institution | 0 | 0.00% | - | 2026-03-31 |
| Bank of America Corporation | Institution | 0 | 0.00% | - | 2026-03-31 |
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