Angle PLC (QX) (ANPCF) Share Price

ANGLE is a world leading liquid biopsy company with pioneering products in cancer diagnostics. ANGLE's lead product is the Parsortix cell separation system, which captures very rare cells from blood including circulating tumour cells (CTCs) in cancer patient blood even when there is less than one CT... ANGLE is a world leading liquid biopsy company with pioneering products in cancer diagnostics. ANGLE's lead product is the Parsortix cell separation system, which captures very rare cells from blood including circulating tumour cells (CTCs) in cancer patient blood even when there is less than one CTC in one billion healthy cells. The resulting liquid biopsy (simple blood test) enables the investigation of mutations in the patient's cancer for personalised cancer care. ANGLE sells instruments and cassettes for RUO only worldwide and also sells IVD product for use in metastatic breast cancer (MBC) - the Parsortix PC1 Clinical System is FDA cleared for its intended use in MBC and is the first and only FDA cleared medical device to harvest intact CTCs from blood. ANGLE completed an FDA Class II De Novo process. ANGLE is also undertaking clinical studies to support the launch of laboratory developed tests, the first one of which is in ovarian cancer for a clinical application to triage women having surgery for an abnormal pelvic mass to identify those with ovarian cancer. Three 200 patient clinical studies have reported positive headline data with the test optimized and a the most recent 200 patient validation study reported best in class ROC-AUC of 95.4%. A prostate cancer study is in progress. ANGLE has established clinical laboratories in the UK and US and sells services to biopharma for assay development and clinical trials support, as CTCs offer a unique insight. Show more