Apellis Pharmaceuticals Inc (APLS) Options

IKT is having a great run!

APLS at a bottom channel

$60.00, that didn’t take long!

I like the way this traded today, $60 in the near future on news?

Holding up well..

Finally! Back up 14% today.

Shorts got another 12 to 13% since you're warning, let's hope your warning sticks today...

APLS Time to Cover Shorts just like i told the shorts last week on ARGX to Buy to Cover

Closed out of puts at 99% profit on this one. Only three week hold.

Why is stock up so much???

Stock up big today.

FDA announcement soon.

Puts are very pricey and out of the money. Sell for cash to acct.

Why up today? As stock goes up, puts go up too. Strange.

Will we get FDA approval???

Heavy premium in the puts and calls.

2/8/23 regulatory decision due on Empavali.

Huge Market

Drug trial for dry AMD slows progression of disease

Posted: Tuesday 29 March 2022

A drug being trialled for dry age-related macular degeneration (AMD) can significantly reduce the progression of the disease, according to new studies.

Phase three trials have shown that injections of a drug called pegcetacoplan resulted in a significant reduction in the rate at which the cells of the macular degenerate.

The studies by Apellis Pharmaceuticals built on previous research which showed that dry AMD is linked to the complement system and a hyperactive immune response that damages the eyes. Pegcetacoplan is a complement system inhibitor, meaning it aims to prevent this response from happening and harming healthy cells and tissue.

The studies involved two phase three clinical trials (DERBY and OAKS) involving more than 1,250 patients with late stage dry AMD, often referred to as geographic atrophy (GA). As part of the trials some patients received injections monthly, while others received them every other month.

In the combined results of the two trials, patients who received the drug monthly showed up to a 21% reduction in progression of the disease after 18 months, while those who were injected every other month had a 17% reduction.

Jeffrey S. Heier, principal investigator of the DERBY study from Ophthalmic Consultants of Boston, said: “It is exciting to see these positive data with pegcetacoplan, which showed continuous and potentially improving effects over time. These 18-month results provide further evidence that pegcetacoplan meaningfully slows disease progression and has the potential to preserve vision longer.”

He added: “In my practice, I have seen how devastating it can be for people living with GA to lose more of their vision year after year. There is an urgent unmet need in GA, and these results reinforce the potential of pegcetacoplan to become the first-ever treatment for patients with this debilitating disease.”

The study also found that pegcetacoplan was generally safe and well tolerated by those on the trial.

Results of the studies are to be submitted to the US Food and Drug Administration (FDA) for review by the end of June 2022, with the hope that the drug will be licenced for use in the USA.

Going back to 60 this week

looks like insider dumping may be happening again.. damnit

Be careful with this company.
There was a great PR.
An insider dump.
Then a 7 million share under-market private placement.
Then another insider dump the next day.

Scam company.

* * $APLS Video Chart 01-07-2020 * *

Link to Video - click here to watch the technical chart video

First! Holding $40 2/21 call... waiting on trial results!