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| Holder | Type | Held (Actual) | % of Outstanding | Market Value | Date Reported |
|---|---|---|---|---|---|
| Perceptive Capital Solutions Holdings | Institution | 2,352,500 | 21.26% | US$ 26.42M | 2024-12-31 |
| Farallon Capital Management, L.L.C. | Institution | 2,250,000 | 20.33% | US$ 25.27M | 2026-03-31 |
| One Fin Capital Management LP | Institution | 843,482 | 7.62% | US$ 9.47M | 2026-03-31 |
| RA Capital Management, L.P. | Institution | 750,000 | 6.78% | US$ 8.42M | 2026-03-31 |
| RA Capital Healthcare Fund, L.P. | Institution | 750,000 | 6.78% | US$ 8.42M | 2025-12-05 |
| RTW Investments, LP | Institution | 742,500 | 6.71% | US$ 8.34M | 2026-03-31 |
| BIT Capital GmbH | Institution | 740,264 | 6.69% | US$ 8.31M | 2026-03-31 |
| Holocene Advisors, LP | Institution | 625,173 | 5.65% | US$ 7.02M | 2026-03-31 |
| IPConcept Fund Management SA | Institution | 620,264 | 5.60% | US$ 6.97M | 2025-12-08 |
| One Fin Capital Master Fund Lp | Institution | 603,072 | 5.45% | US$ 6.77M | 2026-01-06 |
| Aberdeen Group Plc | Institution | 578,565 | 5.23% | US$ 6.50M | 2026-04-01 |
| 683 Capital Management, LLC | Institution | 561,923 | 5.08% | US$ 6.31M | 2026-03-31 |
| FMR LLC | Institution | 505,223 | 4.56% | US$ 5.67M | 2026-03-31 |
| ADAR1 Capital Management, LLC | Institution | 499,581 | 4.51% | US$ 5.61M | 2026-03-31 |
| Sculptor Capital Management, Inc. | Institution | 424,700 | 3.84% | US$ 4.77M | 2026-03-31 |
| ADAR1 Partners, LP | Institution | 402,925 | 3.64% | US$ 4.52M | 2025-12-31 |
| Empyrean Capital Partners, LP | Institution | 282,100 | 2.55% | US$ 3.17M | 2026-03-31 |
| Ikarian Capital, LLC | Institution | 240,951 | 2.18% | US$ 2.71M | 2026-03-31 |
| Balyasny Asset Management L.P. | Institution | 162,434 | 1.47% | US$ 1.82M | 2026-03-31 |
| Boothbay Fund Management, LLC | Institution | 161,437 | 1.46% | US$ 1.81M | 2026-03-31 |
| Alpha Wave Global, LP | Institution | 156,988 | 1.42% | US$ 1.76M | 2026-03-31 |
| Shay Capital LLC | Institution | 150,984 | 1.36% | US$ 1.70M | 2026-03-31 |
| Lighthouse Investment Partners, LLC | Institution | 150,750 | 1.36% | US$ 1.69M | 2026-03-31 |
| DLD Asset Management, LP | Institution | 126,083 | 1.14% | US$ 1.42M | 2026-03-31 |
| LMR Partners LLP | Institution | 117,421 | 1.06% | US$ 1.32M | 2026-03-31 |
| CRCM L.P. | Institution | 116,245 | 1.05% | US$ 1.31M | 2026-03-31 |
| CRCM Institutional Master Fund (BVI), Ltd | Institution | 99,600 | 0.90% | US$ 1.12M | 2026-03-31 |
| Lineage Point Capital LP | Institution | 80,258 | 0.73% | US$ 901.30k | 2026-03-31 |
| FNY Investment Advisers, LLC | Institution | 65,370 | 0.59% | US$ 734.11k | 2026-03-31 |
| Millennium Management LLC | Institution | 62,264 | 0.56% | US$ 699.22k | 2026-03-31 |
| Spearhead Insurance Solutions Idf, Llc | Institution | 53,795 | 0.49% | US$ 604.12k | 2025-12-31 |
| Eagle Health Investments LP | Institution | 37,686 | 0.34% | US$ 423.21k | 2026-03-31 |
| Longaeva Partners L.P. | Institution | 36,614 | 0.33% | US$ 411.18k | 2026-03-31 |
| J. Goldman & Co., L.P. | Institution | 31,428 | 0.28% | US$ 352.94k | 2026-03-31 |
| Mr. Mark McKenna | Insider | 30,000 | 0.27% | US$ 336.90k | 2024-12-31 |
| Dr. Kenneth Song | Insider | 30,000 | 0.27% | US$ 336.90k | 2024-12-31 |
| Dr. Harlan Waksal | Insider | 30,000 | 0.27% | US$ 336.90k | 2024-12-31 |
| Moore Capital Management, LP | Institution | 25,000 | 0.23% | US$ 280.75k | 2026-03-31 |
| Shaolin Capital Management LLC | Institution | 25,000 | 0.23% | US$ 280.75k | 2026-03-31 |
| Virtu Financial, Inc. | Institution | 23,234 | 0.21% | US$ 260.92k | 2026-03-31 |
| Schonfeld Strategic Advisors LLC | Institution | 15,030 | 0.14% | US$ 168.79k | 2026-03-31 |
| Susquehanna International Group, LLP | Institution | 13,851 | 0.13% | US$ 155.55k | 2026-03-31 |
| Hudson River Trading LLC | Institution | 11,045 | 0.10% | US$ 124.04k | 2026-03-31 |
| Readystate Asset Management LP | Institution | 10,987 | 0.10% | US$ 123.38k | 2026-03-31 |
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