Anavex Life Sciences Corporation (AVXL) Options

The Mysterious Flow of Fluid in the Brain.

https://www.quantamagazine.org/the-mysterious-flow-of-fluid-in-the-brain-20250326/

If that is true maybe Cruz's bill will have a chance to help us, as an end around. That is, if this little planned stockholder campaign doesn't work.

Wouldn't it makes sense to wait until there is an FDA filing before putting on a contact campaign?

That's not how it went down with the EMA, in fact the opposite

But No Useful Email Addresses

Post it to his X account. You can be sure someone in his dept will read it. If compelling, they will bring it to his attention.

Had a little time this evening to look about a bit. Lets see where we stand relative to who owns Anaxex shares.
Fintel says: Institutional Shares (Long) 34,715,010 - 40.81% (ex 13D/G) - change of 1.78MM shares 5.40% MRQ
So whatever their sources are they say we are UP 1.78MM shares which is 5.4% more than the end of year quarter. We do get accurate numbers for end of year on Feb 15th. Yes SEC rules say those institutions have to file 45 days after the end of each quarter. Forms 13F/D/G. Looking a bit more at this info Fintel says:
Institutional Owners 304 total, 295 long only, 0 short only, 9 long/short - change of 11.76% MRQ MRQ = Most Recent Quarter.
So then for some the question is who gives a Hoot how many shares and who else owns AVXL. Well somehow for the most part these "Tutes" maybe know more than those of us who post to Investors Hub. Or maybe we come very close to matching the "Tutes" ability to know what and when to buy what stocks. We are fortunate to have quite a few posters to Ihub who have different methods of finding and posting information. Some great. Some good. Some are maybe BOTS But by reading all you soon learn who really is interested and own shares in AVXL. and the WHY they own those shares. All of us are here hoping to make some $$$ some of us are here because we think that Anavex does have the Magic bullet that won't solve ALZ but for damned sure will greatly slow the advancement of ALZ. Put me in that box. Picked Anavex back in 2015. Time to end this diatribe and get a little sleep. Reference to previous post.
Since I am anything but anonymous if you don't think so just put my moniker into your favorite search engine. Those of us with a federal HamRadio license can not hide.
off for a few hours of ZZZZZZzzzz time.
John k9uwa

It's like high school except the people are anonymous, which makes some people even worse.

LOL not if he includes his autobiography :)

How would prioritizing 2-73 for the USA "screw the EMA"? There is plenty of 2-73 to go around and any country that approves it would see large benefits. If both the EMA and the FDA approve then both Europeans and Americans will benefit, right?

Agree that 2-73 would be a boon both financially and efficacy-wise...but doesn't that require that the new Administration prioritize science over emotion? It is possible that the Trump administration WILL move to approve 2-73 expeditiously but I still haven't read anything that makes a case for why that would happen other than wishful thinking.

Bunch of garbage!

No worries! I don’t post much here anymore. Social Media everywhere, has been corrupted by so many unscrupulous people.

i forgot to mention that we can expect topline data from the Phase 2 trial using Anavex 3-71 as a treatment for schizophrenia by or before June 30, 2025.

The OLE (open label extension) study results for the Alzheimer’s blarcamesine study will be released next week!!!

The 120 day stop #1 for the EMA questions should be received by the end of April 2025!!!

The 2nd quarter fiscal results should be released during a teleconference that will include a question and answer section regarding updates on activities around the first week of May 2025!!!

There should be an annual shareholders meeting ASM around the middle of June 2025!!!

Good luck and GOD bless,

It's their media...I would just request if they can forward an email to RFK Jr...Or provide an email that could help you...It doesn't hurt to try.

They will look at the safety aspects. Blarcamesine is the number 1 safest CNS drug ever developed to this day in over 10 years of proven drug trial results and endorsed by 58 of the best doctor / scientist in the world through peer review study. Winner. imo

I don't think the FDA is on board.
They've looked the fool in the Alzheimer's space lately.
I think Dr. Missling is doing an end around and will let peer pressure do the work for him.

Point made. I think the AD advocacy groups will be exerting a fair amount of pressure once the NDA is filed.

Sure would be a good thing to get that filed. Anavex maybe waiting to get past the initial clock stop and being sure that the questions are satisfactorily answered before filing. That would allow Anavex to address any issues raised by CHMP in the NDA filing and hopefully enhance the chances of approval.

Sounds like you will save yourself the embarrassment 👌

To Whom?
You can send it here...OCRMedia@hhs.gov
Thanks. HHS is the right government agency. But I looked around, can't find who or what this email goes to? What is the position or duty of the person who opens emails with this email address? What or who is "OCRMedia?"

Important to know. My email has to address and say exactly the right things from the first word. I need to know who will be reading my email (and its attached Anavex Life Science Corp Medical Science PDF report I'll create). Otherwise, the PDF gets dumped off by a low-level functionary into the file "Strange and Questionable Emails;" unread and internally unshared.

***********
Not useful. Just found that this email is Office for Civil Rights of HHS.

Still looking for a way to email my PDF to proper, high-level HHS officials.

In advertising they used to say you have to see something 7 times before you'll act, so I see no harm in planting a seed.

nice overlay, Citrati...thanks for the visual comparison

It's all magical thinking, and it's not confined to the FDA.

Wouldn't it makes sense to wait until there is an FDA filing before putting on a contact campaign?

I will give you a possible answer to your question about why would today's FDA care about Blarcamisine. Because the entire Trump administration is transactional and if they can see a way to screw the EMA and bring forth the only drug that can save the govt. billions of $$$$ with no side effects they will do it. I hope that Anavex can make some headway in Washington. Maybe that is why Nell was there last week. I hope she was there with others like Missling and team but that might be asking for too much. But if they can get an audience with the right people ie. RFK jr. and tell the story about the greatest data ever seen for an Alzheimer's drug with no side effects , maybe they can get us a fast track designation and beat the EMA to approval. They got Covid approved pretty quick, why not Alz.

He may not believe in any medications, regardless of studies. The most effective medications in human history - vaccines - apparently mean nothing to him. He just fired the head of the FDA's vaccines group. What makes anyone here hopeful that this Administration would "believe in" 2-73? Serious question, not political. I just don't understand why anyone thinks an FDA that no longer leads with science would be good for Anavex. Can anyone who is hopeful please explain? TIA.

You can send it here...OCRMedia@hhs.gov

The OLE (open label extension) study results for the Alzheimer’s blarcamesine study will be released next week!!!

The 120 day stop #1 for the EMA questions should be received by the end of April 2025!!!

The 2nd quarter fiscal results should be released during a teleconference that will include a question and answer section regarding updates on activities around the first week of May 2025!!!

There should be an annual shareholders meeting ASM around the middle of June 2025!!!

Good luck and GOD bless,

But No Useful Email Addresses
"This is RFK’s contact page, with all of his social media contacts."
Of course, those were the publicly-listed contacts for RFK Jr., which I first checked to find a useful email address that would get a message to RFK Jr's desk, or to someone working closely with him, an office aide, etc.

But, no email addresses for anyone at either of the organizations; merely generic snail mail addresses to the organizations.

If ever I can get a valid email address that connects to someone close to RFK Jr. I'll send my detailed PDF which will tell how FDA approval of blarcamesine will be so helpful. But, understandably, no such email addresses are publicly available. Too much junk would be generated that would clog the administrative works of HHS.

I'll wait to see if I can learn of an appropriate recipient's email address. With that, I'll construct the detailed PDF that will clearly tell the story of Anavex science and how, when implemented, it will transform 21st-century medical care and therapies.

What is the number one reason new drugs fail in the CNS space? It's the safety of the drug fails for all sorts of reasons. What does Blarcamesine bring that no other CNS drug "ever" has? Blarcamesine brings the safest profile drug with over 10 years of proven drug trial results. That is reason alone it will be approved at the EMA. That doesn't even take in consideration all the proven positives it brings. Blarcamesine is a block buster drug in the making. Imo.

I asked my wife to look into this.
Hope it helps.

"This is RFK’s contact page, with all of his social media contacts. If the guy makes a good explanation one of these contacts should work. I would suggest he bombard all of the contact points. I would also suggest he work in the words “Make America Healthy Again” and outline his main points in the post as well as including his PDF."



https://www.hhs.gov/about/leadership/robert-kennedy.html

https://www.mahaaction.com/

IF one looks at AVXL relative to sector movement (XBI) for the last month, AVXL has done very well.
XBI is the solid thick black line.

https://investorshub.advfn.com/uimage/uploads/2025/3/29/iljlnScreen_Shot_2025-03-29_at_9.10.16_AM.png

Hopefully, there will be a press release on Monday April 7, 2025 that will include the PowerPoint presentation from the conference.

Unless someone is planning on attending the conference, I believe that is the best we can hope for.

Good luck and GOD bless,

Sat.April 5--OLE Attention Study---any way we can listen to this Presentation ????? TIA

🤩.....yes, hope so!

Investor
I do pay attention!

You have clearly stated that getting past Clock Stop One would be an important factor, even though you have no favorable leanings towards TA, I think I have learned quite a bit about how things add up fundamentally!

Being open minded, I consider these things you have pointed out since mid 2021 to me as very worthwhile, thanks!

golden cross is 50 day below 200 day....has NOT happened yet

Mike:

It's below the last important low which was around $7.71....the 200 day is $7.35.......the trend channel I used was clearly broken a few days ago and is a negative which I had mentioned.

it's certainly not negative at this point and waiting for several things to be cleared up such as the OLE data and the "estimated result of clock stop one". near April 25th?...those are fundamental factors which are most likely key, rather than any TA adjustments I attempt to make on the price movement (momentum) and targets which remain as reasonable upside estimates. The channel breakdown along with the loss of RSI above 50, MACD turn to touching the red (not as yet black below red). Also, the Bollinger Band is back to the lower end (support).

I would suggest using the Weekly Chart since the daily has turned negative short term. This pattern looks still very good to me, with a strong RSI, strong OBV, OK Bollinger Band, weaker MACD...but the pattern remains favorable to me!

https://bigcharts.marketwatch.com/advchart/frames/frames.asp?show=&insttype=Stock&symb=avxl&x=38&y=9&time=12&startdate=1%2F4%2F1999&enddate=4%2F12%2F2018&freq=2&compidx=aaaaa%3A0&comptemptext=&comp=none&ma=1&maval=55550&uf=8&lf=2&lf2=8&lf3=4&type=4&style=350&size=4&timeFrameToggle=false&compareToToggle=false&indicatorsToggle=false&chartStyleToggle=false&state=11

That depends strongly on...
Investor, do you have something better you can suggest?
whether blarcamisine is approved or not.

Absolutely!

Our chances of approval just went considerable up, that's a fact.

They are now desperately looking for something, anything that can help just a little bit.

Our chances of app is now over 90%.

Doc and Investor, do you have something better you can suggest?

Another question; If you or one of your loved ones was diagnosed with AD and you have the option of 2-73 or one of the mapps, what would you choose?

I don't mind sharing what I would choose: 2-73 of course!!

It does - just as I have said before,

So your day to day predictions are better?

Oh wait, you don't make predictions in the short term, you just jab at those who do.

OMG. Would that mean the the odds of approval would be more than 83%?

Here is what today looks like relative to horizontal support/resistance zone and the upward channel.

https://investorshub.advfn.com/uimage/uploads/2025/3/29/zbcxmScreen_Shot_2025-03-28_at_10.49.55_PM.png

And still LLY stock closed green but this POS went down 9%.

I am telling the TRUTH. Look it up if you don't believe me

Pantheon and Syntagon combined give Anavex the production process control and capacity to produce Blarcamesine for commercialization and worldwide distribution and sales.

https://patheon.com/

https://www.syntegon.com/company

Good luck and GODbless,

EMA reject Lilly's AD drug:
https://endpts.com/european-regulator-rejects-lilly-alzheimers-drug-over-side-effects/

Well played sir. Probably should send Noem and Bondi for back up.

Hi Gerry. Plenty of OSD is made right here in the USA. There is loads of capacity here in the states - both at major pharma companies and at CMOs. We do get quite a lot of our antibiotics from offshore - it is messy business - but if Trump was talking about OSD or biologics then he is wrong. Production is fairly well balanced with consumption in each market: Ireland is a hub in the EU for production for the EU market, of course, and companies like to diversify risk and have production in different geographic regions, too. Pharma is one of the few manufacturing businesses where the US market is still a leader (or the leader.)

These are the actual contract manufactures that make Anavex’s blarcamesine

Pantheon and Syntagon combined give Anavex the production process control and capacity to produce Blarcamesine for commercialization and worldwide distribution and sales.

https://patheon.com/

https://www.syntegon.com/company

Good luck and GOD bless,

Anything? Or simply up, down or sideways.

I don't put a lot of stock in chart predictions but I'm showing the 200 day MA is at 7.35 and rising steadily. Life is unpredictable and anything can happen.

Golden cross became death cross...cup and handle became head and shoulder.