Affymetrix Axiom® Strawberry Genotyping Array Delivers Automated Analysis for High-Resolution Genome Scanning of Octoploid S...
October 22 2013 - 5:30AM
Business Wire
Affymetrix, Inc. (NASDAQ:AFFX) announces the launch of Axiom
Strawberry Genotyping Array (also called International Strawberry
90K SNP array or IStraw90), the only solution that successfully
enables high-resolution genotyping and fully automated data
analysis of the octoploid strawberry genome. This 90,000 SNP array
will enable complex trait research and set the stage for
multi-trait, marker-assisted breeding of the cultivated garden
strawberry (Fragaria × ananassa).
The cultivated garden strawberry is an allo-octoploid with a
chromosome number of 2n=8x=56. While there are other genotyping
technologies available to scan genomes of agricultural species at
high resolution, most have been designed for diploids. With
Affymetrix’ advanced bioinformatics and innovative design strategy,
Axiom Genotyping Solution provides genome-wide genotyping and
accurately calls the genotypes of both diploid and polyploid
species. This technology has already been successfully applied to
complex genomes such as maize, rose, wheat, trout, and salmon.
Axiom Strawberry Genotyping Array was designed through a
public-private partnership between Affymetrix and
the International RosBREED SNP Consortium (IRSC), an arm of
the "RosBREED" project dedicated to the genetic improvement of
rosaceous crops. The RosBREED team including Genotyping Team Leader
Nahla Bassil (USDA-ARS, Corvallis), Demonstration Breeder Tom Davis
(University of New Hampshire geneticist), and Pedigree-Based
Analysis Team Leader Eric van de Weg (Wageningen University &
Research Center) partnered with the Affymetrix array design and
bioinformatics teams to devise SNP selection and data analysis
strategies. RosBREED announced the availability of the array
through its September 2013 newsletter. Preliminary results from the
array were presented at the 2013 annual conference of the American
Society for Horticultural Science.
“IStraw90 gives us the capability to create high-resolution
genetic maps of the strawberry genome and work towards enabling
marker-assisted breeding for strawberry breeders worldwide,” stated
Nahla Bassil. “The International RosBREED SNP consortium has been
working towards enabling discovery and validation of valuable trait
loci. IStraw90 will facilitate many of RosBREED’s goals and
expedite marker-assisted breeding in strawberry.”
“The successful design and analysis of the data from the
allo-octoploid strawberry genome was possible only because of the
expertise, commitment, and collaborative efforts of the Axiom
myDesign custom array, bioinformatics, and product support teams
within Affymetrix,” stated Eric van de Weg. “It is awesome to have
the tools to construct such high marker-density maps generated in
such a short time. We expect this array to be a valuable resource
for genome-wide analysis and marker-assisted breeding in many
American, European and other breeding programs.”
“Genotyping the octoploid strawberry genome demonstrates the
power and precision of the Axiom Genotyping platform to type
genetic variants within complex genomes,” said Andy Last, Executive
Vice President of the Genetic Analysis Business Unit at Affymetrix.
“The array design process and updates to the automated analysis
software used with Axiom Strawberry Genotyping Array are
significant milestones for our platform because they enable the
worldwide plant and animal genotyping community to leverage the
Axiom myDesign customization process and analysis software to
genotype even more species of interest.”
Axiom Strawberry Genotyping Array will complement the catalog of
Axiom Agrigenomics Genotyping Arrays that are available for
multiple species, including bovine, chicken, and buffalo. These
products have been used for genome-wide association studies,
quantitative trait locus mapping, genome mapping, and breeding
activities that make use of marker-assisted selection and genomic
selection. As scientists make progress in decoding genomes of
various plants, animals, and fish using next-generation sequencing
platforms, they can advance their research and commercial
objectives by translating those discoveries to routine applications
on the Axiom Genotyping platform.
To learn more about Axiom Genotyping Solutions, please visit
www.affymetrix.com/axiom for applications in human diseases
research and www.affymetrix.com/agrigenotyping for applications in
agrigenomics.
PLEASE NOTE: Affymetrix, the Affymetrix logo, Axiom, and
all other trademarks are the property of Affymetrix, Inc. All other
trademarks are the property of their respective owners.
Forward-looking statements
All statements in this press release that are not historical are
"forward-looking statements" within the meaning of Section 21E of
the Securities Exchange Act as amended, including statements
regarding Affymetrix' "expectations," "beliefs," "hopes,"
"intentions," "strategies," or the like. Such statements are
subject to risks and uncertainties that could cause actual results
to differ materially for Affymetrix from those projected. These and
other risk factors are discussed in Affymetrix' Form 10-K for the
year ended December 31, 2012, and other SEC reports for subsequent
quarterly periods.
About Affymetrix
Affymetrix technologies enable multiplex and simultaneous
analysis of biological systems at the cell, protein, and gene
level, facilitating the rapid translation of bench-top research
into clinical and routine use for human health and wellness.
We strive to provide leadership and support, partnering with our
customers in pharmaceutical, diagnostic, and biotechnology
companies, as well as leading academic, government, and non-profit
research institutes in their quest for answers toward using biology
for a better world.
More than 2,300 microarray systems have been shipped around the
world and more than 48,000 peer-reviewed papers have been published
citing our technologies. Affymetrix is headquartered in Santa
Clara, California, and has manufacturing facilities in Cleveland,
Ohio, San Diego, Vienna and Singapore. The Company has about 1,100
employees worldwide and maintains sales and distribution operations
across Europe, Asia, and Latin America. For more information about
Affymetrix, please visit www.affymetrix.com.
Affymetrix, Inc.Media Contact:Mindy Lee-Olsen,
408-731-5523Vice President, Marketing
Servicesmindy_lee-olsen@affymetrix.comorInvestor
Contact:Doug Farrell, 408-731-5285Vice President, Investor
Relationsdoug_farrell@affymetrix.com
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