ART Advanced Research Technologies Inc. (ART) (TSX: ARA), a Canadian medical device company and a leader in optical molecular imaging products for the healthcare and pharmaceutical industries, announced today its financial results for the first quarter ended March 31, 2009. ART reported revenues of $95,914 for the three-month period ended March 31, 2009, compared to $1,241,921 for the same quarter a year ago. For the 2009 first quarter, the operating loss increased by $145,231, or 11%, to $1,479,552 from $1,334,321 for the same period a year ago. The Company posted a net loss of $1,391,413 ($0.02 per share) for the 2009 first quarter, compared to $1,279,456 ($0.01 per share) for the corresponding 2008 period. All dollar amounts referenced herein are in U.S. dollars, unless otherwise stated.

2009 First Quarter Highlights

- In January 2009, ART further reduced expenses and streamlined the Company, in response to the deteriorating global economic climate.

Post Quarter Events

- ART secured the sale of SoftScan� breast imaging device to Gottingen University in Germany, where the device will be used to measure treatment response for breast cancer.

- Gottingen has also committed to purchase a second SoftScan system, fully upgraded for use in screening with molecular probes, subject to grant funding.

- ART participated in the American Association of Cancer Research (AACR) conference in Denver, Colorado, which was well attended and generated a number of important leads for ART, further consolidating our sales funnel.

Revenues

For the three-month period ended March 31, 2009, sales amounted to $95,914, compared to $1,241,921 for the same quarter a year ago. During the quarter ended March 31, 2009, sales mainly resulted from the sale of Fenestra products whereas for the same quarter ended March 31, 2008, the Company sold one SoftScan unit, one Optix unit, Fenestra products, and add-ons. During the first quarter of 2009, the Company sold service contracts, and recognized a total of $25,218 in services and other revenues. In the first quarter of 2008, the Company had recognized revenue from service contracts in the amount of $35,709, concluded in the last quarter of 2007.

Gross Margin

During the three-month period ended March 31, 2009, ART generated a gross margin ratio of 96% from the sales of its products, compared to 79% for the same period in the previous year. The gross margin ratio generated on the sales of services and other revenues was 69% for the three-month period ended March 31, 2009 compared to 49% for the three-month period ended March 31, 2008. The increase in the product gross margin ratio during the three-month period ended March 31, 2009, resulted from a different sales product mix compared to the three-month period ended March 31, 2008. During the first quarter of 2009, most of the sales resulted from the Fenestra product line which explains the higher gross margin ratio as compared to the first quarter in 2008, during which the Company sold more of its other product lines, namely Optix and SoftScan.

Operating Expenses

The Company's research and development ("R&D") expenditures for the three-month period ended March 31, 2009, net of investment tax credits, amounted to $635,910, compared to $854,650 for the same period a year ago. The decrease of the R&D during the quarter ended March 31, 2009, compared to the same quarter of last year mainly resulted from the cost reduction plan which was put in place during the first days of 2009. As a result, the R&D headcount decreased by approximately 15% compared to the R&D headcount at the end of the first quarter of 2008. During the first quarter of 2009, the R&D team pursued the development of the next generation of the Optix system and continued to support Optix users, while collaborating with clients for the development of applications to demonstrate the utility of the system in research areas such as oncology, cardiology and neurology.

Selling, general, and administrative ("SG&A") expenses for the 2009 first quarter totaled $868,946, compared to $1,283,254 for the same quarter a year ago. The decrease of the SG&A expenses during the quarter ended March 31, 2009, compared to the same quarter last year mainly resulted from the cost reduction plan which took effect during the first days of 2009. In fact, the Company reduced its workforce and implemented a four day shared workweek schedule for about 20 percent of the workforce. Senior management has taken at least a 10 percent salary cut.

Net Loss

The net loss for the quarter ended March 31, 2009 was $1,391,413 or $0.02 per share, compared to $1,279,456 or $0.01 per share for the quarter ended March 31, 2008.

Financial Outlook

As at March 31, 2009, ART had $ 1,450,037 in cash and cash equivalents, and a working capital of $2,742,886. ART is also considering financing options, such as assistance programs for businesses offered by the different levels of government, to strengthen the Company's financial situation.

The financial statements, accompanying notes to the financial statements, and Management's Discussion and Analysis for the three-month period ended March 31, 2009, will be available online at www.sedar.com, or at www.art.ca, in the "Investors" section. Summary financial tables are provided below. A detailed list of the risks and uncertainties affecting the Company can be found in the Management's Discussion and Analysis for the year ended December 31, 2008, and in the Company's most recent Annual Information Form, available on SEDAR at www.sedar.com.

Conference Call

ART will host a conference call today at 5:00 PM (EDT). The telephone number to access the conference call is (514) 861-1531 when dialing within the Montreal area, or (877) 667-7766 for the rest of North America. Outside of North America, please dial (514) 861-1531. A replay of the call will be available until May 28, 2009. To listen to the replay from the Montreal area, please dial (514) 861-2272, or, (800) 408-3053 for the rest of North America. From outside of North America, please dial (514) 861-2272. The access code for the replay is 7643478#.

About ART

ART Advanced Research Technologies Inc. is a leader in molecular imaging products for the healthcare and pharmaceutical industries. ART has developed products in medical imaging, medical diagnostics, disease research, and drug discovery with the goal of bringing new and better treatments to patients faster. The Optix� optical molecular imaging system, designed for monitoring physiological changes in living systems at the preclinical study phases of new drugs, is used by industry and academic leaders worldwide. The SoftScan� optical medical imaging device is designed to improve the diagnosis and treatment of breast cancer. Finally, the Fenestra� line of molecular imaging contrast products provides image enhancement for a wide range of preclinical Micro CT applications allowing scientists to see greater detail in their imaging studies, with potential extension into other major imaging modalities. ART is commercializing some of these products in a global strategic alliance with GE Healthcare, a world leader in mammography and imaging. ART's shares are listed on the TSX under the ticker symbol ARA. For more information on ART, visit our website at www.art.ca.

This press release may contain forward-looking statements subject to risks and uncertainties that would cause actual events to differ materially from expectations. These risks and uncertainties are described in the most recent Annual Information Form and the financial statements for the year ended December 31, 2008, available on SEDAR (www.sedar.com).


ART Advanced Research Technologies Inc.
Balance Sheets
(In U.S. dollars)

                                         March 31, 2009  December 31, 2008
                                             (unaudited)
--------------------------------------------------------------------------
ASSETS
Current assets
  Cash                                       $1,450,037         $1,446,086
  Term deposits (2008 - 0.67% and 0.90%
   matured in January 2009)                           -          1,700,000
  Accounts receivable                         1,505,477          1,700,365
  Investment tax credits receivable             330,950            779,682
  Inventories                                 1,179,554          1,168,702
  Prepaid expenses                              504,440            547,127
--------------------------------------------------------------------------
                                              4,970,458          7,341,962
Property, equipment and equipment under
 capital leases                                 381,129            415,932
Patents                                       1,421,896          1,462,918
Deferred development costs                    2,576,895          2,383,180
--------------------------------------------------------------------------
                                             $9,350,378        $11,603,992
--------------------------------------------------------------------------

LIABILITIES
Current liabilities
  Bank loan                                     476,115            489,956
  Accounts payable and accrued liabilities    1,587,044          2,224,509
  Deferred revenues                             129,552            112,926
  Current portion of obligations under
   capital leases                                34,861             35,267
--------------------------------------------------------------------------
                                              2,227,572          2,862,658

Obligations under capital leases                 29,222             39,271
--------------------------------------------------------------------------
--------------------------------------------------------------------------
                                              2,256,794          2,901,929

SHAREHOLDERS' EQUITY
Share capital and share purchase warrants    39,087,613         39,142,553
Contributed surplus                           4,912,643          4,845,266

Deficit                                     (37,802,104)       (36,410,691)
Accumulated other comprehensive income          895,432          1,124,935
--------------------------------------------------------------------------
                                            (36,906,672)       (35,285,756)
--------------------------------------------------------------------------
--------------------------------------------------------------------------
                                              7,093,584          8,702,063
--------------------------------------------------------------------------
                                             $9,350,378        $11,603,992
--------------------------------------------------------------------------
--------------------------------------------------------------------------



ART Advanced Research Technologies Inc.
Shareholders's Equity
As at March 31, 2009
(In U.S. dollars)

                                    Common Shares         Preferred Shares
--------------------------------------------------------------------------
                             Number        Amount      Number       Amount
--------------------------------------------------------------------------
Balance as at January 1,
 2008                    94,540,592   $23,030,023   8,341,982   $7,907,043
Net loss
Translation adjustment
--------------------------------------------------------------------------
Comprehensive loss
--------------------------------------------------------------------------

Issue of shares for cash                           53,101,296    7,100,000
Share issue expenses
Stock-based compensation
Deferred share units
Expired warrants
--------------------------------------------------------------------------
Balance as at December
 31, 2008                94,540,592    23,030,023  61,443,278   15,007,043
--------------------------------------------------------------------------
(unaudited)
Net loss
Translation adjustment
--------------------------------------------------------------------------
Comprehensive loss
--------------------------------------------------------------------------

Stock-based compensation
Expired warrants
--------------------------------------------------------------------------
Balance as at March 31,
 2009                    94,540,592   $23,030,023  61,443,278  $15,007,043
--------------------------------------------------------------------------


                                                             Share Capital
                                                                 and Share
                                                                  Purchase
                                                   Warrants       Warrants
--------------------------------------------------------------------------
                                       Number        Amount          Total
--------------------------------------------------------------------------
Balance as at January 1, 2008       4,855,791    $1,280,876    $32,217,942
Net loss
Translation adjustment
--------------------------------------------------------------------------
Comprehensive loss

--------------------------------------------------------------------------

Issue of shares for cash                                         7,100,000
Share issue expenses
Stock-based compensation
Deferred share units
Expired warrants                     (594,907)     (175,389)      (175,389)
--------------------------------------------------------------------------
Balance as at December 31, 2008     4,260,884     1,105,487     39,142,553
--------------------------------------------------------------------------
(unaudited)
Net loss
Translation adjustment
--------------------------------------------------------------------------
Comprehensive loss
--------------------------------------------------------------------------

Stock-based compensation
Expired warrants                     (200,000)      (54,940)       (54,940)
--------------------------------------------------------------------------
Balance as at March 31, 2009        4,060,884     1,050,547     39,087,613
--------------------------------------------------------------------------


                                                  Accumulated
                                                        Other
                     Contributed                Comprehensive
                         Surplus        Deficit        Income        Total
--------------------------------------------------------------------------
--------------------------------------------------------------------------
Balance as at
 January 1, 2008      $4,537,336   $(31,007,264)   $3,326,739   $9,074,753
Net loss                             (4,819,230)                (4,819,230)
Translation adjustment                             (2,201,804)  (2,201,804)
--------------------------------------------------------------------------
Comprehensive loss                   (4,819,230)   (2,201,804)  (7,021,034)
--------------------------------------------------------------------------

Issue of shares for
 cash                                                            7,100,000
Share issue expenses                   (584,197)                  (584,197)
Stock-based
 compensation             84,065                                    84,065
Deferred share units      48,476                                    48,476
Expired warrants)        175,389
--------------------------------------------------------------------------
Balance as at December
 31, 2008              4,845,266    (36,410,691)    1,124,935    8,702,063
--------------------------------------------------------------------------
(unaudited)
Net loss                             (1,391,413)                (1,391,413)
Translation adjustment                               (229,503)    (229,503)
--------------------------------------------------------------------------
Comprehensive loss                   (1,391,413)     (229,503)  (1,620,916)
--------------------------------------------------------------------------

Stock-based
 compensation             12,437                                    12,437
Expired warrants          54,940
--------------------------------------------------------------------------
Balance as at March 31,
 2009                 $4,912,643   $(37,802,104)     $895,432   $7,093,584
--------------------------------------------------------------------------



ART Advanced Research Technologies Inc.
Operations
(In U.S. dollars)
(Unaudited)

                                        Three-month periods ended March 31
--------------------------------------------------------------------------
                                                   2009               2008
--------------------------------------------------------------------------
Sales
  Products                                      $70,696         $1,206,212
  Services and other revenues                    25,218             35,709
--------------------------------------------------------------------------
                                                 95,914          1,241,921
--------------------------------------------------------------------------
Cost of sales
  Products                                        2,498            247,793
  Services and other revenues                     7,705             18,105
--------------------------------------------------------------------------
                                                 10,203            265,898
--------------------------------------------------------------------------
Gross margin                                     85,711            976,023
--------------------------------------------------------------------------
Operating expenses
  Research and development, net of investment
   tax credits                                  635,910            854,650
  Selling, general and administrative           868,946          1,283,254
  Amortization                                   60,407            172,440
--------------------------------------------------------------------------
                                              1,565,263          2,310,344
--------------------------------------------------------------------------
Operating loss                                1,479,552          1,334,321
Financial revenues                              (88,139)           (54,865)
--------------------------------------------------------------------------
Net loss                                     $1,391,413         $1,279,456
--------------------------------------------------------------------------
Basic and diluted net loss per share              $0.02              $0.01
--------------------------------------------------------------------------
Basic and diluted weighted average number
 of common shares outstanding                94,540,592         94,540,592
--------------------------------------------------------------------------



ART Advanced Research Technologies Inc.
Notes to Financial Statements
(In U.S. dollars)
(Unaudited)

                                        Three-month Periods ended March 31
--------------------------------------------------------------------------
                                                   2009               2008
--------------------------------------------------------------------------
OPERATING ACTIVITIES
Net loss                                    $(1,391,413)       $(1,279,456)
Items not affecting cash
  Amortization                                   60,407            172,440
  Stock-based compensation                       12,457             37,080
Net changes in working capital items
  Accounts receivable                           148,611            395,929
  Investment tax credits receivable             431,812          1,140,069
  Inventories                                   (44,392)            55,489
  Prepaid expenses                               27,556           (842,236)
  Accounts payable and accrued liabilities     (581,498)           239,539
  Deferred revenues                              20,054            (35,709)
  Deferred grant                                      -              5,821
--------------------------------------------------------------------------
Cash flows from operating activities         (1,316,406)          (111,034)
--------------------------------------------------------------------------
INVESTING ACTIVITIES
Acquisition of property and equipment            (6,301)                 -
Proceeds on disposal of property and equipment        -             25,691
Patents                                         (31,087)           (89,175)
Deferred development costs                     (264,162)          (295,171)
--------------------------------------------------------------------------
Cash flows from investing activities           (301,550)          (358,655)
--------------------------------------------------------------------------
FINANCING ACTIVITIES
Repayment of obligations under capital
 leases                                          (8,449)            (5,538)
--------------------------------------------------------------------------
Cash flows from financing activities             (8,449)            (5,538)
Effect of foreign currency translation
 adjustments on cash and cash equivalents       (69,644)          (116,739)
--------------------------------------------------------------------------
                                                (78,093)          (122,277)
--------------------------------------------------------------------------
Net decrease in cash and cash equivalents    (1,696,049)          (591,966)
Cash and cash equivalents, beginning of
 period                                       3,146,086          3,587,654
--------------------------------------------------------------------------
Cash and cash equivalents, end of period     $1,450,037         $2,995,688
--------------------------------------------------------------------------
CASH AND CASH EQUIVALENTS
Cash                                         $1,450,037         $1,001,331
Term deposits                                         -          1,994,357
--------------------------------------------------------------------------
                                             $1,450,037         $2,995,688
--------------------------------------------------------------------------
Supplemental disclosure of cash flow
 information
Interest paid                                    $8,062             $8,634
Interest received                                 1,403             23,750
Fixed assets acquired by means of capital
 leases                                               -            129,403
--------------------------------------------------------------------------

Contacts: ART Advanced Research Technologies Inc. Jacques Bedard Chief Financial Officer 514-832-0777 jbedard@art.ca www.art.ca

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