BriaCell to Present Clinical and Immune Activity at AACR Annual Meeting
February 26 2020 - 5:30AM
BriaCell Therapeutics Corp. (“BriaCell” or the
“Company”) (TSX-V:BCT) (OTCQB:BCTXF), a clinical-stage
biotechnology company specializing in targeted immunotherapy for
advanced breast cancer, is pleased to announce that it has been
selected to present at the American Association for Cancer Research
(AACR) Annual Meeting, taking place on April 24–April 29, 2020 in
San Diego, California. The Company will present the clinical and
pharmacodynamic activity (i.e. tumor regression and immune
responses) to Bria-IMT™ from the Phase I/IIa studies of Bria-IMT™
alone or in combination with checkpoint inhibitors in advanced
breast cancer.
Blood and tumor analysis were used to evaluate
clinical and pharmacodynamic responses to Bria-IMT™ in patients
with advanced breast cancer from two phase I-IIa trials. The
results of evaluation in both clinical studies (23 patients treated
with Bria-IMT™ as monotherapy; and 11 patients treated with
Bria-IMT™ in combination with KEYTRUDA® and/or INCMGA00012),
including tumor regression and immune activation, will be presented
focusing on patients with certain biologic characteristics. The
safety profile of the treatments will be discussed in both clinical
trials.
The details of BriaCell’s AACR poster are as
follows: Abstract Control
Number: 4449Title: Clinical and
pharmacodynamic responses to a modified whole tumor cell
immunotherapy in patients with advanced breast cancer from two
phase I-IIa trialsSession
Category: ImmunologySession
Title: ImmunotherapySession
Date: Tuesday, April 28, 2020 Time:
1:30 PM - 5:00 PM PSTLocation: San Diego
Convention Center, Exhibit Halls A-F, Poster Section
47Poster Board Number: 21Permanent
Abstract Number: 5588
Following the presentation, a copy of the poster
will be posted on
https://briacell.com/novel-technology/scientific-publications/.
“We are excited to present the latest data on
our immunotherapy, including safety, immune activity and anti-tumor
responses, in advanced breast cancer patients. We will be
describing treatment responses in patients with certain biomarkers
including HLA types and cancer grades,” said Dr. Bill Williams,
BriaCell’s President & CEO. “In our view, it is critical
to identify high responding patient groups in order to focus on the
patients most likely to benefit from the immune responses generated
by our immunotherapy. We will continue to move forward in our
goal of creating highly effective, targeted treatments for advanced
breast cancer patients with no effective treatment options.”
“Our clinical and immunological findings will
inform further development of our novel immunotherapy. This will be
key in determining if our therapy may work additively or
synergistically with checkpoint inhibitors to boost the body's
immune response to cancer cells as we strive to develop effective
treatment options for advanced breast cancer patients."
About AACR
The AACR was founded in Washington, D.C., May 7,
1907, by a group of 11 physicians and scientists intending “to
further the investigation and spread the knowledge of cancer.” To
prevent and cure cancer using research, education, communication,
collaboration, funding and advocacy has been the mission of AACR.
With its programs and services, AACR advances research in cancer
and related biomedical science by facilitating exchange of
knowledge and innovations among scientists and clinicians dedicated
to the fight against cancer, providing education and training in
oncology treatment and advancing cancer etiology, prevention, early
detection, diagnosis and treatment worldwide.
For more information on AACR, please visit:
https://www.aacr.org.
About BriaCell
BriaCell is an immuno-oncology focused
biotechnology company developing targeted and effective approaches
for the management of cancer.
For additional information on BriaCell, please
visit: https://briacell.com/.
Cautionary Note Regarding Forward-Looking
Information
Except for the statements of historical fact,
this news release contains "forward-looking information" within the
meaning of the applicable Canadian securities legislation which are
subject to known and unknown risks relevant to the Company in
particular and to the biotechnology and pharmaceutical industries
in general, uncertainties and other factors that may cause actual
events to differ materially from current expectation. These risks
are more fully described in the Company's public filings available
at www.sedar.com.
These forward-looking statements include, but
are not limited to, BriaCell’s plans, objectives, expectations and
intentions. Such forward-looking statements reflect BriaCell's
current beliefs and are based on information currently available to
management. Although the forward-looking statements contained in
this news release are based upon what BriaCell believes are
reasonable assumptions, there can be no assurance that actual
results will be consistent with these forward-looking
statements.
Readers are cautioned not to place undue
reliance on these forward-looking statements, which speak only as
of the date of this press release. The Company disclaims any
intention or obligation, except to the extent required by law, to
update or revise any forward-looking statements, whether as a
result of new information, future events or otherwise.
Neither TSX Venture Exchange nor its Regulation
Services Provider (as that term is defined in the policies of the
TSX Venture Exchange) accepts responsibility for the adequacy or
accuracy of this release.
Contact Information
For further information, please
contact:BriaCell Therapeutics Corp.:Farrah
DeanManager, Corporate DevelopmentEmail: farrah@BriaCell.com Phone:
1-888-485-6340
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