4basebio PLC
("4basebio", the "Company" or the “Group”)
Half-yearly for
the six months ended 30 June 2021
4basebio PLC (AIM: 4BB) (formerly 4basebio UK Societas), the
specialist life sciences group focused on exploiting intellectual
property in the field of cell and gene therapies and DNA vaccines,
announces its unaudited half-yearly results for the six months
ended 30 June 2021.
Operational Highlights (including post
period end)
- Conversion to PLC status following approval at the Annual
General Meeting
- DNA manufacturing facility expected to be completed by year
end
- Positive validation studies on use of 4basebio synthetic DNA
versus plasmid DNA
- Multiple patent filings across DNA synthesis and nanoparticle
delivery technology
- Evaluation and collaboration licence agreements signed with
Royal Holloway
Financial Highlights
- Cash balances of £12.1 million at period end
- Cash runway into 2023 before calling on available debt
facility
- Loss for the period of £1.7 million (H1 2020 loss: £0.38
million)
- Net cash outflow from operating activities of £1.7
million (H1 2020: £0.51 million )
Commenting on the interim results, Dr. Heikki Lanckriet, CEO and CSO, said “We
are extremely pleased with the progress achieved during the first
half of 2021. In particular, we are increasingly confident
that during the course of 2022 we will be able to manufacture
meaningful quantities of DNA for resale. Initially this will
be for research and pre-clinical purposes while we look to secure
GMP approvals for our manufacturing suites. We are also very
pleased to confirm that as expected, we intend to be completing
those manufacturing suites by the end of 2021.
As we move towards manufacturing
capacity, our aim is to work with prospective customers to
highlight the benefits of our technologies. We remain very
positive about the commercial prospects of both our synthetic DNA
and non-viral vector technology across a range of
applications.”
For further enquiries, please
contact:
4basebio
PLC |
+44 (0)12 2396
7943 |
Heikki Lanckriet, CEO and CSO |
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|
Cairn Financial Advisers LLP
(Nominated Adviser) |
+44 (0)20 7213
0880 |
Jo Turner / Sandy Jamieson |
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|
finnCap Ltd (Broker) |
|
Geoff Nash/Richard
Chambers/Charlotte Sutcliffe |
+44 (0)20 7220
0500 |
Notes to Editors
4basebio (AIM: 4BB) is a specialist life sciences group focused
on therapeutic DNA for cell and gene therapies and DNA vaccines and
providing solutions for effective and safe delivery of these DNA
based products to patients. It is the intention of the Company to
become a market leader in the manufacture and supply of high
purity, synthetic DNA for research, therapeutic and pharmacological
use and develop non-viral vectors for the efficient delivery of
payloads. The immediate objectives of 4bb are to validate and scale
its DNA synthesis and advance its collaborations to facilitate the
functional validation of its DNA based products and cell and gene
delivery solutions.
Chairman’s Statement
Introduction
Following shareholder approval of the Annual General Meeting
held on 30 June 2021, the Company
subsequently completed its conversion to a PLC from a UK Societas
upon its registration at Companies House on 20 July 2021.
The Board is pleased to report that 4basebio continues to make
good progress during the first half of the year in validating and
commercialising 4basebio DNA and nanoparticle delivery
technology. The Group has established strong R&D groups
in both the UK and Spain which
have been able to focus on improving and scaling processes
surrounding its synthetic DNA manufacture as well as also
strengthening its intellectual property, with patent filings across
its portfolio.
4basebio has also made excellent progress in validating its DNA,
being able to demonstrate strong performance of its synthetic DNA
in comparison with plasmid DNA through a number of
programmes.
Also as previously noted, it remains our intention to have DNA
manufacturing in place by the end of 2021 with a view to commencing
sale of DNA during 2022. We remain firmly on track to achieve
these objectives. We also continue to explore further
commercial applications for our DNA and nanoparticles as outlined
below.
Operational Review
As we reported in our 2020 Annual Report, the Group remains
pre-revenue and it is focussed on the development of its DNA
synthesis and non-viral vector technology. Both technologies
have broad application in gene and cell therapy as well as
vaccines. We see particular opportunities opening up in AAVs
(adeno-associated viral vectors) for gene therapy and in-vitro
transcription (IVT) for the production of mRNA vaccines.
With the objective of reaching commercial DNA manufacturing as
swiftly as possible, the decision was made during H1 to develop
both AAV and mRNA research laboratories within our Cambridge facility for the purpose of
optimising DNA constructs for use in these applications. Both
labs are now operational with recruitment ongoing and with the
near-term objective of being able to place our DNA products into
the hands of prospective customers for testing within their own AAV
and mRNA systems.
During the second half of 2021 the product and technology
application focus is expanding to include gene editing and cell
therapy based applications with the recruitment of relevant
expertise underway.
Alongside the focus on construct optimisation and application
research, there is continued development work on the upscaling of
DNA production for commercial sale. With this objective
central in our thinking, we have commenced work on our pilot 4,400
square foot clean room installation; and we expect this to be
complete by the end of 2021. This will provide for seven DNA
synthesis suites. The facility will then undergo testing and
validation with a view to becoming operational during Q1 2022 and
with the intention of manufacturing research and pre-clinical grade
DNA while working to secure GMP accreditation during the remainder
of 2022.
The earmarked capital commitment for this project is about £1.5
million. When fully operational, the theoretical production
capacity of this facility, at prevailing market prices is expected
to exceed £25 million per annum.
Following consideration of the overall resource requirements for
the DNA and nanoparticle sides of the business, it has been decided
to expand research laboratory space within the existing
Cambridge facility. As a
result, the clean room installation will be located in a separate
facility also near Cambridge and
four miles from head office. (The Company has secured a lease over
this site for a period of 15 years, with suitable break clauses.)
The manufacturing suites and associated quality management systems
will be operated by a dedicated team, which will work independently
in this standalone production facility.
A key consideration in executing on our strategy is the ability
to recruit appropriately skilled team members. The Group is
competing for candidates in a rapidly growing market segment but
despite these challenges, 4basebio has continued growing its teams,
with Group headcount expected to be about 35-40 FTEs by year
end.
Alongside these developments, the Group continues to file patent
applications relating to further innovation around hpDNA™, osDNA™
and Hermes™ nanoparticles. We have filed our first two
applications protecting the use of Hermes™ nanoparticles for
specific applications as well as additional filings protecting
hpDNA™ and osDNA™ manufacturing processes and uses. We
believe continued investment in intellectual property is a
cornerstone of enhancing the value of the Group’s technology.
As noted earlier, 4basebio also continues to progress its
collaboration projects including its project with Royal Holloway focussed on Duchenne muscular
dystrophy, with 4basebio screening for an optimised delivery
vector. Whilst the overall project is expected to run
for two years; we are pleased to note that certain aspects are
progressing more quickly than originally planned. In
particular, 4basebio has made very good progress in in-vitro models
in identifying nanoparticles with strong affinity for muscle cells;
and we are now progressing to in-vivo models to validate and
optimise these particles.
Coronavirus
The impact of COVID-19 on operations has been very modest.
The Group continues to adhere to local COVID protocols in the UK
and Spain.
Business outlook
The Group expects to continue investing in its technologies and
team members during 2021 and 2022. Modest non-core revenues
are expected at levels consistent with previous periods; ongoing
expenditure will continue to be much greater than revenues, with
the Group consequently recording a loss for the year. This is
as previously indicated.
During the latter half of the year, 4basebio expects to make
several further patent filings and continue with its range of
research and development projects, both internally and with
collaborators. The Group also expects to have concluded the
physical build out of its clean rooms by the end of 2021, with GMP
certification being sought during the course of 2022.
Financial Review
Comparative information
As explained in note 2 to the interim results, the prior period
comparatives for the period ended 30 June 2020 reflect solely
the financial performance and position of 4basebio S.L.U. The
results for period ended 31 December
2020 include 4basebio PLC and 4basebio S.L.U. for the whole
year and 4basebio PLC’s UK subsidiaries from the date of the spin
out, 8 December 2020. The consolidated balance sheet as at
31 December 2020 includes 4basebio
PLC and all subsidiary companies.
The results for the period ended 30 June
2021 and the consolidated balance sheet at that date reflect
the consolidated performance and position of 4basebio PLC and all
its subsidiary companies
Revenue
Revenue in the first six months of 2021 (“H1 2021”) was £0.18
million (H1 2020: £0.16 million ). Consistent with previous
periods, this reflects legacy revenue streams including kits sales
and licence income.
Cost of sales
Cost of sales in H1 2021 was £38k (H1 2020: £86k).
As noted in the 2020 Annual Report, cost of sales reflects
primarily the amortisation on previously capitalised intangible
assets linked to kit sales.
Selling and administration
expenses
Selling, general and administrative expenses were a combined
£1.2 million in H1 2021 (H1 2020: £0.24 million ). Prior period
expenses reflect the expenditure in 4basebio S.L.U. only, while the
current period includes the now significantly larger UK
operations.
Research and development
Overall research and development expenditure for H1 2021 was
£0.86 million (H1 2020: £0.28 million ), of which £0.23 million was
capitalised in the period (H1 2020: £0.14 million ). Overall
expenditure increased due to the expansion of the UK team which
commenced late 2020 and remains ongoing. Capitalised
expenditure relates to platform research undertaken in Spain.
Tax
Tax represents R&D tax credits expected to be recovered in
relation to expenditure during the first half of the year.
Balance sheet
Non-current assets increased to £2.5 million at 30 June 2021 from £2.3 million at 31 December 2020; this related to fixed asset
additions in the UK. Current assets fell to £12.8
million at 30 June 2021 from £15.5
million at 31 December 2020, due
primarily to cash outflows during the first half of 2021. As
a result, closing cash balances at 30 June
2021 stood at £12.1 million (31
December 2020: £15 million).
Current liabilities decreased to £0.64 million at 30 June 2021 from £0.83 million at 31 December 2020 due to the repayment of
softloans in the first part of the year. Long
term financial liabilities reduced due to reclassification of
softloans from long term to short term liabilities. As a
result, overall long term liabilities stood at £1.3 million as at
30 June 2021 (31 December 2020: £1.5 million). Other long term
liabilities represent deferred grant income in Spain.
Share Capital at both 30 June 2021
and 31 December 2020 reflects the
capital contributions arising from the spin out process as
explained in the Annual Report for 2020 and note 2 to the interim
results.
Cash flow
Net cash outflows from operations were £1.7 million for the six
months ended 30 June 2021 (period
ended 30 June 2020: outflow of £0.53
million ). This reflects the step change in operations
between the periods as presented in the profit and loss account; in
particular the upscaling of UK operations. Operating
cash outflows for the current period also include £360 thousand
relating to the AIM listing in February
2021.
Cash outflows from investing reflect planned investments in
capital expenditure across the group and capitalised development
expenditure in 4basebio S.L.U..
Cashflows from financing for the period ended 30 June 2021 reflect Spanish softloan repayments,
while the prior period shows net cash inflows from the then parent
4basebio AG (now 2Invest AG). The large cash inflow for the
year ended 31 December 2020 reflects
the spin out process accounting as explained in the 2020 Annual
Report.
Exchange differences for the period represent changes in the
British pound value of cash balances held in foreign currency,
almost entirely euro denominated.
Tim McCarthy
Chairman
30 September 2021
Consolidated statement of profit or loss and other
comprehensive income
for the six months ended 30 June
2021
|
|
|
|
|
|
|
|
[in
£‘000] |
Note |
Six
months ended 30 June 2021 (unaudited) (note 2) |
Six months ended 30 June 2020 (unaudited) (note
2) |
Year ended 31 December 2020
(audited)
(note 2) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Revenues |
|
|
4 |
179 |
159 |
462 |
Cost of
goods sold |
|
|
|
(38) |
(86) |
(188) |
Gross
profit |
|
|
141 |
73 |
274 |
|
|
|
|
|
|
|
|
Sales and
marketing expenses |
|
|
|
(81) |
(79) |
(141) |
Administration expenses |
|
|
(1,155) |
(163) |
(516) |
Research
and non-capitalised development expenses |
|
(633) |
(138) |
(343) |
Other
operating expenses |
|
(103) |
(78) |
(1) |
Other
operating income |
|
15 |
15 |
105 |
Loss
from operations |
|
(1,816) |
(370) |
(622) |
|
|
|
|
|
|
|
|
Finance
expense |
|
|
|
(31) |
(11) |
(94) |
|
|
|
|
|
|
|
Loss
before tax |
|
|
|
(1,847) |
(381) |
(716) |
|
|
|
|
|
|
|
|
Income tax
credit / expense |
|
|
5 |
197 |
- |
(3) |
|
|
|
|
|
|
|
Loss for
the period |
|
|
|
(1,650) |
(381) |
(719) |
|
|
|
|
|
|
|
|
Loss per
share |
6 |
|
|
|
|
- Diluted and Undiluted (in £/share)
|
|
(0.13) |
(0.05) |
(0.08) |
|
|
|
|
|
|
|
|
Items
that may be reclassified to the income statement in subsequent
periods |
|
|
|
|
|
Exchange
rate adjustments |
|
(393) |
(11) |
162 |
|
|
|
|
|
|
Total
comprehensive income |
|
|
(2,043) |
(392) |
(557) |
|
|
|
|
|
|
|
|
|
|
|
All of the loss for each period is from continuing
operations.
Consolidated statement of financial position
30 June 2021
[in £’000] |
|
|
|
Note |
30 June
2021
(unaudited)
(note 2) |
31
December 2020
(audited)
(note 2) |
|
|
|
|
|
|
|
Assets |
|
|
|
|
|
|
|
|
Intangible
assets |
7 |
937 |
785 |
Property,
plant and equipment |
8 |
1,501 |
1,478 |
Other
non-current assets |
|
32 |
34 |
Non-current assets |
2,470 |
2,297 |
|
|
|
|
Inventories |
|
101 |
131 |
Trade
receivables |
|
120 |
39 |
Other
current assets |
|
551 |
341 |
Cash and
cash equivalents |
9 |
12,064 |
15,001 |
Current
assets |
12,836 |
15,512 |
|
|
|
|
|
|
|
Total
assets |
|
15,306 |
17,809 |
|
|
|
|
|
|
|
Liabilities |
|
|
|
|
|
|
|
Financial
liabilities |
|
(223) |
(416) |
Trade
payables |
|
(150) |
(96) |
Other
current liabilities |
|
(241) |
(301) |
Current
liabilities |
|
(614) |
(813) |
|
|
|
|
Financial
liabilities |
|
(1,051) |
(1,301) |
Other
liabilities |
|
(226) |
(237) |
Non-current liabilities |
|
(1,277) |
(1,538) |
|
|
|
|
Total
liabilities |
|
(1,891) |
(2,351) |
Net
assets |
|
13,415 |
15,458 |
|
|
|
|
Share
capital |
|
11,130 |
11,130 |
Share
premium |
|
706 |
706 |
Merger
reserve |
|
688 |
688 |
Capital
reserve |
|
13,099 |
13,099 |
Foreign
exchange reserve |
|
(218) |
175 |
Share based
payments reserve |
|
(35) |
- |
Profit and
loss reserve |
|
(11,955) |
(10,340) |
Total
Equity |
10 |
13,415 |
15,458 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Consolidated statement of changes in equity
for the six months ended 30 June
2021
[in £‘000] |
Share
capital |
Share premium |
Merger reserve |
Capital reserve |
Foreign exchange |
Share based payments |
Profit
and loss reserve |
Total equity |
Balance at 1
January 2020 (audited) |
6,362 |
- |
- |
1,356 |
13 |
- |
(9,621) |
(1,890) |
Capital contributions
from 4basebio AG (now 2Invest AG) |
- |
- |
- |
11,743 |
- |
- |
- |
11,743 |
Combination
accounting |
(6,258) |
- |
688 |
- |
- |
- |
- |
(5,570) |
Loss after income
tax |
- |
- |
- |
- |
- |
- |
(719) |
(719) |
Shares issued for
cash |
3,209 |
706 |
- |
- |
- |
- |
- |
3,915 |
Foreign Exchange
difference arising on translation of 4basebio S.L.U. |
- |
- |
- |
- |
162 |
- |
- |
162 |
Shares issued to
acquire subsidiaries |
7,817 |
- |
- |
- |
- |
- |
- |
7,817 |
Balance at 31
December 2020 (audited) |
11,130 |
706 |
688 |
13,099 |
175 |
- |
(10,340) |
15,458 |
|
|
|
|
|
|
|
|
|
[in £‘000] |
Share
capital |
Share premium |
Merger reserve |
Capital reserve |
Foreign exchange |
Share based payments |
Profit
and loss reserve |
Total equity |
Balance at 1
January 2021 (audited) |
11,130 |
706 |
688 |
13,099 |
175 |
- |
(10,340) |
15,458 |
Loss after income tax
and total comprehensive income for the period |
- |
- |
- |
- |
- |
- |
(1,650) |
(1,650) |
Share option
charge |
- |
|
|
- |
|
(35) |
35 |
- |
Foreign Exchange
difference arising on translation of 4basebio S.L.U. |
- |
- |
- |
- |
(393) |
- |
- |
(393) |
Balance at 30 June
2021 (unaudited) |
11,130 |
706 |
688` |
13,099 |
(218) |
(35) |
(11,955) |
13,415 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Consolidated statement of cash flows
for the six months ended 30 June
2021
|
|
|
|
|
|
|
[in
£’000] |
|
30 June
2021
(unaudited)
(note 2) |
30
June
2020
(unaudited)
(note 2) |
31
December 2020
(audited)
(note 2) |
|
|
|
|
|
Net
loss for the period |
|
(1,650) |
(381) |
(719) |
Adjustments to reconcile net loss for the period to net
cashflows |
|
|
|
Income
taxes |
(197) |
- |
3 |
Interest
charge |
|
31 |
3 |
94 |
Depreciation of property, plant and equipment |
106 |
30 |
83 |
Amortisation and impairment of intangible assets |
41 |
87 |
194 |
Other
non-cash items |
52 |
12 |
25 |
Working
capital changes: |
|
|
|
|
Trade
receivables and other current assets |
(99) |
(34) |
91 |
|
Trade
payables and other current liabilities |
|
24 |
(138) |
(876) |
|
Inventories |
|
26 |
(92) |
(24) |
Tax
receipt |
|
- |
- |
107 |
Net Cash
flows from operating activities |
|
(1,666) |
(513) |
(1,022) |
|
|
|
|
Investments in property, plant and equipment and intangible
assets |
(141) |
(126) |
(351) |
Investments
in capitalised development |
(231) |
(142) |
(498) |
Cash
acquired with 4basebio Limited (now 4basebio UK Limited) |
- |
- |
2,295 |
Cash
flows from investing activities |
(372) |
(268) |
1,446 |
|
|
|
|
Cash
in(out)flow due to changes in financing |
(337) |
1,244 |
(1,024) |
Capital
contributions by way of cash |
- |
- |
15,626 |
Interest
paid |
(31) |
(3) |
(116) |
IFRS16
leases |
(64) |
(18) |
(59) |
Cash
flows from financing activities |
(432) |
1,223 |
14,427 |
|
|
|
|
Net change
in cash and cash equivalents |
(2,470) |
442 |
14,851 |
Exchange
differences |
(467) |
22 |
70 |
|
|
|
|
Cash
and cash equivalents at the beginning of the period |
15,001 |
80 |
80 |
Cash and
cash equivalents at the end of the period |
12,064 |
544 |
15,001 |
|
|
|
|
|
|
|
|
|
|
|
|
Notes to the financial statements
For the six months ended 30 June
2021
1.General information
4basebio PLC, formerly known as 4basebio UK Societas, is
registered in England and
Wales as a public limited company
since 20 July 2021. Prior to that
date it was registered as a United Kingdom Societas under the name
4basebio UK Societas. The conversion to a public limited company
occurred following shareholder approval of the conversion at its
Annual General Meeting held on 30 June 2021. With the
conversion, the name of the Company changed to 4basebio PLC.
The Company is domiciled in England and the registered office of the
Company is 25 Norman Way, Over, Cambridge, CB24 5QE. 4basebio PLC is the
parent of a group of companies. The group structure remains
the same as that shown in the Company’s financial statements for
the year ended 31 December 2020. The Group focusses on life
sciences and in particular the development of synthetic DNA and
nanoparticles suitable for inclusion in, or delivery of,
therapeutic payloads for cell or gene therapies and gene
vaccines.
The interim report was approved by the board of directors on
29 September 2021.
The Company trades on London Stock Exchange’s AIM market, having
been admitted on 17 February 2021. The international
securities number (ISIN) number for its AIM traded shares changed
on 29 July 2021 to GB00BLD8ZL39
reflecting the conversion to a PLC; its ticker symbol is 4bb.l.
2.Significant accounting policies
Basis of preparation
As set out in the Company’s annual report and financial
statements for the year ended 31 December
2020, the directors considered the circumstances giving rise
to the formation of the Group and relevant guidance in IFRS 3.B13
to IFRS 3.B17, and concluded that the combination, on 8 December 2020, in which the Company issued
8,622,231 shares to the shareholders of its former parent entity as
consideration for the spin-off assets comprising shareholdings in
4basebio S.L.U. and 4basebio Limited (now 4basebio U.K. Limited),
should be treated as a continuation of 4basebio S.L.U. at historic
book values for the purposes of the Company’s statutory financial
statements.
Therefore, this consolidated interim financial information for
the six months ended 30 June 2021 is
in substance the continuation of the financial information of
4basebio S.L.U. The consolidated financial information for the six
months ended 30 June 2021 comprises
the results of 4basebio S.L.U., 4basebio UK Limited, 4basebio
Discovery Limited and 4basebio PLC for the full period presented.
The financial information for the comparative period ended
30 June 2020 precedes the date of the
combination and, consequently, reflects the results and position of
4basebio S.L.U. This financial information does not
constitute statutory accounts but has been prepared under IFRS and
in accordance with the group accounting policies disclosed in the
Company’s statutory financial statements for the year ended
31 December 2020, as well as the
share based payments accounting policy described below.
Share based payments
Where share options are awarded to employees, the fair value of
the options at the date of grant is charged to the Statement of
Comprehensive Income over the vesting period. The fair value is
measured at the date of grant and spread over the period during
which the employees become unconditionally entitled to the options.
The fair value of options granted under the share option schemes is
measured using a probability adjusted Black Scholes model.
Non-market vesting conditions are taken into account by adjusting
the number of equity instruments expected to vest at each reporting
date so that, ultimately, the cumulative amount recognised over the
vesting period is based on the number of options that eventually
vest. The estimated probability of market vesting conditions is
factored into the fair value of the options granted. Where the
terms and conditions of options are modified before they vest, the
increase in the fair value of the options, measured immediately
before and after the modification, is also charged to the Statement
of Comprehensive Income over the remaining vesting period.
Significant judgments
The significant judgments made in relation to the financial
statements are further set out below.
Going concern
The directors have, at the time of approving the interim report,
a reasonable expectation that the Group has adequate resources to
continue in operational existence for the foreseeable future. Thus,
they continue to adopt the going concern basis of accounting in
preparing the financial statements.
Internally?generated intangible assets –
research and development expenditure
Development expenditure is capitalised when the conditions
referred to in Note 2 of the Company's 2020 annual report are met.
Estimates and underlying assumptions are reviewed on an ongoing
basis. Revisions to accounting estimates are recognised in the
period in which the estimate is revised if the revision affects
only that period or in the period of the revision and future
periods if the revision affects both current and future
periods.
3.Foreign currencies
The functional currency of the Group is British Pounds.
The principal currency rate of the Group other than the British
Pounds is the euro which has developed as follows in relation to
the equivalent of one pound (GBP/£):
[in
GBP] |
Closing exchange rate |
Average exchange rate |
|
30.06.2021 |
31.12.2020 |
|
|
Six
months ended 30.06.2021 |
Six
months ended 30.06.2020 |
Year ended 31.12.2020 |
Euro |
0.8581 |
0.9089 |
|
|
0.8678 |
0.8740 |
0.8895 |
|
|
|
|
|
|
|
|
|
|
4.Revenues
Revenue by type
[in £’000] |
Six
months ended 30.06.2021 |
Six
months ended 30.06.2020 |
Year ended 31.12.2020 |
|
Revenue from sales of
kits and other products |
168 |
137 |
428 |
|
Revenue from licences
and royalties |
11 |
22 |
34 |
|
|
|
|
|
|
Total
revenue |
179 |
159 |
462 |
|
Geographic
markets
[in £‘000] |
Six
months ended 30.06.2021 |
Six months ended 30.06.2020 |
Year ended 31.12.2020 |
|
Europe |
59 |
74 |
115 |
|
|
USA |
120 |
85 |
347 |
|
|
|
|
|
|
|
|
Total
revenue |
179 |
159 |
462 |
|
|
|
|
|
|
|
|
|
|
|
5.Income taxes
The Group anticipates claiming R&D tax credits in both the
UK and Spain in relation to the
year ended 31 December 2021. The quantum of such claims for
the first half of the year is estimated at £197 thousand.
The tax loss carry forwards for which no deferred tax assets
were recognised across the Group amounted to approximately £10.8
million (31 December 2020: £10.0
million).
6.Loss per share
|
Six
months ended 30.06.2021 |
Six
months ended 30.06.2020 |
Year
ended 31.12.2020 |
Numerator [in
£‘000] |
|
|
|
Result for the
period |
(1,650) |
(381) |
(719) |
Denominator
[number of shares] |
|
|
|
Weighted average
number of registered shares in circulation (ordinary shares) for
calculating the undiluted earnings per share |
12,317,473 |
7,488,854 |
9,197,913 |
|
|
|
|
Diluted and
Undiluted earnings per share |
(0.13) |
(0.05) |
(0.08) |
7.Intangible assets
[in £‘000] |
Development costs |
Licences |
Total |
|
Cost or acquisition
value |
|
|
|
|
01.01.2020 |
1,434 |
86 |
1,520 |
|
Additions |
463 |
35 |
498 |
|
Disposals |
- |
- |
- |
|
Exchange
differences |
90 |
7 |
97 |
|
31.12.2020 |
1,987 |
128 |
2,115 |
|
|
|
|
|
|
01.01.2021 |
1,987 |
128 |
2,115 |
|
Additions |
227 |
4 |
231 |
|
Disposals |
- |
- |
- |
|
Exchange
differences |
(94) |
(8) |
(102) |
|
31.12.2021 |
2,120 |
124 |
2,244 |
|
|
|
|
|
|
Cumulative
amortisation and impairment |
|
|
|
|
01.01.2020 |
1,052 |
18 |
1,070 |
|
Amortisation |
188 |
6 |
194 |
|
Disposals |
- |
- |
- |
|
Exchange
differences |
64 |
2 |
66 |
|
31.12.2020 |
1,304 |
26 |
1,330 |
|
|
|
|
|
|
01.01.2021 |
1,304 |
26 |
1,330 |
|
Amortisation |
39 |
2 |
41 |
|
Disposals |
- |
- |
- |
|
Exchange
differences |
(63) |
(1) |
(64) |
|
30.06.2021 |
1,280 |
27 |
1,307 |
|
|
|
|
|
|
Net book
value |
|
|
|
|
31.12.2020 |
683 |
102 |
785 |
|
30.06.2021 |
840 |
97 |
937 |
|
|
|
|
|
|
|
8.Property, plant and equipment
[in £‘000] |
Operating equipment |
Land
and buildings |
Usage
rights from leases |
Total |
|
Cost or acquisition
value |
|
|
|
|
|
01.01.2020 |
243 |
- |
75 |
318 |
|
Additions |
187 |
- |
163 |
350 |
|
Acquisition of
subsidiary |
152 |
997 |
- |
1,149 |
|
Disposals |
- |
- |
(79) |
(79) |
|
Exchange
differences |
16 |
- |
6 |
22 |
|
31.12.2020 |
598 |
997 |
165 |
1,760 |
|
|
|
|
|
|
|
01.01.2021 |
598 |
997 |
165 |
1,760 |
|
Additions |
141 |
- |
- |
141 |
|
Disposals |
- |
- |
- |
- |
|
Exchange
differences |
(17) |
- |
(8) |
(25) |
|
30.06.2021 |
721 |
997 |
158 |
1,876 |
|
|
|
|
|
|
|
Cumulative
amortisation and impairment |
|
|
|
|
|
01.01.2020 |
209 |
- |
32 |
241 |
|
Depreciation |
31 |
5 |
46 |
82 |
|
Disposals |
(3) |
- |
(51) |
(54) |
|
Exchange
differences |
12 |
- |
1 |
13 |
|
31.12.2021 |
249 |
5 |
28 |
282 |
|
|
|
|
|
|
|
01.01.2021 |
249 |
5 |
28 |
282 |
|
Depreciation |
50 |
23 |
33 |
106 |
|
Disposals |
- |
- |
- |
- |
|
Exchange
differences |
(11) |
- |
(2) |
(13) |
|
30.06.2021 |
288 |
28 |
59 |
375 |
|
|
|
|
|
|
|
Net book
value |
|
|
|
|
|
31.12.2020 |
349 |
992 |
137 |
1,478 |
|
30.06.2021 |
433 |
969 |
99 |
1,501 |
|
9.Cash and cash equivalents
[in £‘000] |
30.06.2021 |
31.12.2020 |
|
Bank balances and cash
in hand |
12,064 |
15,001 |
|
|
|
|
|
Cash and cash
equivalents |
12,064 |
15,001 |
|
10.Equity
The share capital of 4basebio PLC as of 30 June 2021 and 31
December 2020 amounts to a total of €12,317,473 divided into
12,317,473. These are all registered ordinary shares. There
are no shares with special rights or other restrictions on voting
rights.
Share-based payments
During the period, 542,000 options to subscribe for shares in
the Company were granted to employees with an exercise price of
£1.18 per share and a further 42,500 options to subscribe for
shares in the Company were granted to employees with an exercise
price of £3.65 per share.
The options vest partially on grant and then periodically over
four years, subject to market and non-market facing performance
conditions. A share-based payments charge is recognised as an
expense in the profit or loss over the vesting period, taking
account of the estimated number of shares that will vest and the
probability of achieving market facing vesting conditions. The fair
value of awards granted in the period was measured at the date of
grant using a probability adjusted Black–Scholes option pricing
model. Non-market vesting conditions are taken into account by
adjusting the number of equity instruments expected to vest at each
reporting date so that, ultimately, the cumulative amount
recognised over the vesting period is based on the number of
options that eventually vest. The estimated probability of market
vesting conditions being met is factored into the fair value of the
options granted.
A share-based payments charge of £35,000 has been expensed in
the period with a corresponding amount recognised in equity based
on fair values of between £0.23 and £1.44 per option, as at the
dates of grant.
11.Events after the reporting
period
Conversion to public limited company
On 20 July 2021 the Company was
formally converted from a UK Societas to a public limited company,
following the approval of shareholders at the Annual General
Meeting of 30 June 2021.