Abbott Heart Stent Tops Newer Boston Sci Device In Study
September 23 2009 - 2:13PM
Dow Jones News
A study released Wednesday representing the first big match-up
between Boston Scientific Corp.'s (BSX) Taxus Liberte drug-coated
heart stent and the Xience stent made by Abbott Laboratories (ABT)
showed fewer serious events for Xience patients after a year.
The single-hospital study of 1,800 patients in the Netherlands
may prove important because Abbott-funded clinical trials -
including one released earlier Wednesday - have shown the Xience
stent outperforming an older stent from Boston Scientific that has
essentially been replaced by Taxus Liberte. Unlike clinical trials
that hand-pick patients and may omit certain complications, the
"Compare" study from the Netherlands tracked patients with all
sorts of heart-artery problems as they came through the door.
Such studies can shed light on how devices work in "real-world"
conditions, although they may not have the same rigor as carefully
controlled clinical trials conducted at multiple sites.
The Compare study was presented during the Transcatheter
Cardiovascular Therapeutics conference in San Francisco alongside
the larger Spirit IV study, which showed Xience outperforming the
older Taxus Express device at one year.
Compare's main goal was to track a combination of serious events
including death, non-fatal heart attacks and retreatment of the
previously treated artery. On this measure the rate for Xience at
one year was 6.2%, compared with a 9.1% rate for Taxus Liberte.
Study investigators credited fewer cases of early stent-related
clots and less need for retreatment among Xience patients.
Boston Scientific also gets a cut of the Xience business, since
it sells the Abbott-made stent under the name "Promus" and a
profit-sharing deal. Sales of the home-grown Taxus Liberte stent
are worth more to Boston Scientific, however.
-By Jon Kamp, Dow Jones Newswires; 617-654-6728;
jon.kamp@dowjones.com