TIDMOBD

RNS Number : 9802Q

Oxford BioDynamics PLC

23 October 2023

Oxford BioDynamics Plc

( "OBD" or the "Company" and, together with its subsidiaries, the "Group")

PDMR Dealing / Grant of Share Options

23 October 2023 - Oxford BioDynamics Plc (AIM: OBD, the Company), a biotechnology company developing precision medicine tests for immune health based on the EpiSwitch(R) 3D genomics platform, announces that it has granted a total of 2,500,500 options over its ordinary shares of 1 pence each ("Ordinary Shares"), to Group employees, including certain directors and PDMRs of the Company, as outlined in the table below.

The options were granted under the Company's 2016 Employee Share Option Plan with an exercise price of 34p per share, being the closing share price on 19 October 2023, the day immediately preceding the grant of the options. Prior to the grant, Chief Financial Officer Paul Stockdale surrendered 50,000 share options originally awarded in 2018.

The newly-granted options will vest in three equal tranches on the first, second and third anniversaries of the date of grant. Vested options will remain exercisable up to and including the tenth anniversary of the date of grant.

Following this grant, the individuals referred to above hold options over Ordinary Shares and are interested in Ordinary Shares as follows:

 
                                          New     Total number        Ordinary Shares 
                                      options       of options              held 
                                      granted    over Ordinary 
                                                        Shares 
                                                                    Number     % of current 
                                                                                     issued 
                                                                              share capital 
                                                                ----------  --------------- 
 Alexandre Akoulitchev, Chief 
  Scientific Officer                  250,000        1,596,131   6,603,082            3.26% 
                                    ---------  ---------------  ----------  --------------- 
 Paul Stockdale, Chief Financial 
  Officer                             250,000        1,050,000     331,818            0.23% 
                                    ---------  ---------------  ----------  --------------- 
 Matthew Wakefield, Non Executive 
  Chairman                            150,000          400,000   1,022,727            0.70% 
                                    ---------  ---------------  ----------  --------------- 
 David Holbrook, Non Executive 
  Director                             75,000          115,000           -                - 
                                    ---------  ---------------  ----------  --------------- 
 David Blum, SVP of Marketing         250,000          462,500      75,000            0.04% 
                                    ---------  ---------------  ----------  --------------- 
 Thomas Guiel, Chief Operations 
  Officer                             250,000          650,000     365,000            0.25% 
                                    ---------  ---------------  ----------  --------------- 
 Ewan Hunter, Chief Data Officer      250,000          750,000     136,363            0.09% 
                                    ---------  ---------------  ----------  --------------- 
 

The notifications below, made in accordance with the requirements of UK Market Abuse Regulation, provide further details:

 
      Details of the person discharging managerial responsibilities/person 
  1    closely associated 
 a)   Name                        Alexandre Akoulitchev 
     --------------------------  --------------------------------------------- 
      Reason for the notification 
  2 
     ------------------------------------------------------------------------- 
 a)   Position/status             Director/PDMR 
     --------------------------  --------------------------------------------- 
 b)   Initial notification/       Initial notification 
       Amendment 
     --------------------------  --------------------------------------------- 
      Details of the issuer, emission allowance market participant, 
  3    auction platform, auctioneer or auction monitor 
     ------------------------------------------------------------------------- 
 a)   Name                        Oxford BioDynamics Plc 
     --------------------------  --------------------------------------------- 
 b)   LEI                         2138005Y1TK258O5U928 
     --------------------------  --------------------------------------------- 
      Details of the transaction(s): section to be repeated for 
  4    (i) each type of instrument; (ii) each type of transaction; 
       (iii) each date; and (iv) each place where transactions have 
       been conducted 
     ------------------------------------------------------------------------- 
 a)   Description of the          Ordinary Shares of 1 pence each 
       financial instrument, 
       type of instrument          ISIN: GB00BD5H8572 
       Identification code 
     --------------------------  --------------------------------------------- 
 b)   Nature of the transaction   Grant of share options 
     --------------------------  --------------------------------------------- 
 c)   Price(s) and volume(s)      250,000 ordinary shares at an exercise price 
                                   of 34 pence per share 
     --------------------------  --------------------------------------------- 
 d)   Aggregated information      N/A 
       - Aggregated volume 
       - Price 
     --------------------------  --------------------------------------------- 
 e)   Date of the transaction     20 October 2023 
     --------------------------  --------------------------------------------- 
 f)   Place of the transaction    Outside a trading venue 
     --------------------------  --------------------------------------------- 
 
 
      Details of the person discharging managerial responsibilities/person 
  1    closely associated 
 a)   Name                        David Blum 
     --------------------------  --------------------------------------------- 
      Reason for the notification 
  2 
     ------------------------------------------------------------------------- 
 a)   Position/status             PDMR 
     --------------------------  --------------------------------------------- 
 b)   Initial notification/       Initial notification 
       Amendment 
     --------------------------  --------------------------------------------- 
      Details of the issuer, emission allowance market participant, 
  3    auction platform, auctioneer or auction monitor 
     ------------------------------------------------------------------------- 
 a)   Name                        Oxford BioDynamics Plc 
     --------------------------  --------------------------------------------- 
 b)   LEI                         2138005Y1TK258O5U928 
     --------------------------  --------------------------------------------- 
      Details of the transaction(s): section to be repeated for 
  4    (i) each type of instrument; (ii) each type of transaction; 
       (iii) each date; and (iv) each place where transactions have 
       been conducted 
     ------------------------------------------------------------------------- 
 a)   Description of the          Ordinary Shares of 1 pence each 
       financial instrument, 
       type of instrument          ISIN: GB00BD5H8572 
       Identification code 
     --------------------------  --------------------------------------------- 
 b)   Nature of the transaction   Grant of share options 
     --------------------------  --------------------------------------------- 
 c)   Price(s) and volume(s)      250,000 ordinary shares at an exercise price 
                                   of 34 pence per share 
     --------------------------  --------------------------------------------- 
 d)   Aggregated information      N/A 
       - Aggregated volume 
       - Price 
     --------------------------  --------------------------------------------- 
 e)   Date of the transaction     20 October 2023 
     --------------------------  --------------------------------------------- 
 f)   Place of the transaction    Outside a trading venue 
     --------------------------  --------------------------------------------- 
 
 
      Details of the person discharging managerial responsibilities/person 
  1    closely associated 
 a)   Name                        Thomas Guiel 
     --------------------------  --------------------------------------------- 
      Reason for the notification 
  2 
     ------------------------------------------------------------------------- 
 a)   Position/status             PDMR 
     --------------------------  --------------------------------------------- 
 b)   Initial notification/       Initial notification 
       Amendment 
     --------------------------  --------------------------------------------- 
      Details of the issuer, emission allowance market participant, 
  3    auction platform, auctioneer or auction monitor 
     ------------------------------------------------------------------------- 
 a)   Name                        Oxford BioDynamics Plc 
     --------------------------  --------------------------------------------- 
 b)   LEI                         2138005Y1TK258O5U928 
     --------------------------  --------------------------------------------- 
      Details of the transaction(s): section to be repeated for 
  4    (i) each type of instrument; (ii) each type of transaction; 
       (iii) each date; and (iv) each place where transactions have 
       been conducted 
     ------------------------------------------------------------------------- 
 a)   Description of the          Ordinary Shares of 1 pence each 
       financial instrument, 
       type of instrument          ISIN: GB00BD5H8572 
       Identification code 
     --------------------------  --------------------------------------------- 
 b)   Nature of the transaction   Grant of share options 
     --------------------------  --------------------------------------------- 
 c)   Price(s) and volume(s)      250,000 ordinary shares at an exercise price 
                                   of 34 pence per share 
     --------------------------  --------------------------------------------- 
 d)   Aggregated information      N/A 
       - Aggregated volume 
       - Price 
     --------------------------  --------------------------------------------- 
 e)   Date of the transaction     20 October 2023 
     --------------------------  --------------------------------------------- 
 f)   Place of the transaction    Outside a trading venue 
     --------------------------  --------------------------------------------- 
 
 
      Details of the person discharging managerial responsibilities/person 
  1    closely associated 
 a)   Name                        David Holbrook 
     --------------------------  -------------------------------------------- 
      Reason for the notification 
  2 
     ------------------------------------------------------------------------ 
 a)   Position/status             Director/PDMR 
     --------------------------  -------------------------------------------- 
 b)   Initial notification/       Initial notification 
       Amendment 
     --------------------------  -------------------------------------------- 
      Details of the issuer, emission allowance market participant, 
  3    auction platform, auctioneer or auction monitor 
     ------------------------------------------------------------------------ 
 a)   Name                        Oxford BioDynamics Plc 
     --------------------------  -------------------------------------------- 
 b)   LEI                         2138005Y1TK258O5U928 
     --------------------------  -------------------------------------------- 
      Details of the transaction(s): section to be repeated for 
  4    (i) each type of instrument; (ii) each type of transaction; 
       (iii) each date; and (iv) each place where transactions have 
       been conducted 
     ------------------------------------------------------------------------ 
 a)   Description of the          Ordinary Shares of 1 pence each 
       financial instrument, 
       type of instrument          ISIN: GB00BD5H8572 
       Identification code 
     --------------------------  -------------------------------------------- 
 b)   Nature of the transaction   Grant of share options 
     --------------------------  -------------------------------------------- 
 c)   Price(s) and volume(s)      75,000 ordinary shares at an exercise price 
                                   of 34 pence per share 
     --------------------------  -------------------------------------------- 
 d)   Aggregated information      N/A 
       - Aggregated volume 
       - Price 
     --------------------------  -------------------------------------------- 
 e)   Date of the transaction     20 October 2023 
     --------------------------  -------------------------------------------- 
 f)   Place of the transaction    Outside a trading venue 
     --------------------------  -------------------------------------------- 
 
 
      Details of the person discharging managerial responsibilities/person 
  1    closely associated 
 a)   Name                        Ewan Hunter 
     --------------------------  --------------------------------------------- 
      Reason for the notification 
  2 
     ------------------------------------------------------------------------- 
 a)   Position/status             PDMR 
     --------------------------  --------------------------------------------- 
 b)   Initial notification/       Initial notification 
       Amendment 
     --------------------------  --------------------------------------------- 
      Details of the issuer, emission allowance market participant, 
  3    auction platform, auctioneer or auction monitor 
     ------------------------------------------------------------------------- 
 a)   Name                        Oxford BioDynamics Plc 
     --------------------------  --------------------------------------------- 
 b)   LEI                         2138005Y1TK258O5U928 
     --------------------------  --------------------------------------------- 
      Details of the transaction(s): section to be repeated for 
  4    (i) each type of instrument; (ii) each type of transaction; 
       (iii) each date; and (iv) each place where transactions have 
       been conducted 
     ------------------------------------------------------------------------- 
 a)   Description of the          Ordinary Shares of 1 pence each 
       financial instrument, 
       type of instrument          ISIN: GB00BD5H8572 
       Identification code 
     --------------------------  --------------------------------------------- 
 b)   Nature of the transaction   Grant of share options 
     --------------------------  --------------------------------------------- 
 c)   Price(s) and volume(s)      250,000 ordinary shares at an exercise price 
                                   of 34 pence per share 
     --------------------------  --------------------------------------------- 
 d)   Aggregated information      N/A 
       - Aggregated volume 
       - Price 
     --------------------------  --------------------------------------------- 
 e)   Date of the transaction     20 October 2023 
     --------------------------  --------------------------------------------- 
 f)   Place of the transaction    Outside a trading venue 
     --------------------------  --------------------------------------------- 
 
 
      Details of the person discharging managerial responsibilities/person 
  1    closely associated 
 a)   Name                        Paul Stockdale 
     --------------------------  ----------------------------------------------- 
      Reason for the notification 
  2 
     --------------------------------------------------------------------------- 
 a)   Position/status             Director/PDMR 
     --------------------------  ----------------------------------------------- 
 b)   Initial notification/       Initial notification 
       Amendment 
     --------------------------  ----------------------------------------------- 
      Details of the issuer, emission allowance market participant, 
  3    auction platform, auctioneer or auction monitor 
     --------------------------------------------------------------------------- 
 a)   Name                        Oxford BioDynamics Plc 
     --------------------------  ----------------------------------------------- 
 b)   LEI                         2138005Y1TK258O5U928 
     --------------------------  ----------------------------------------------- 
      Details of the transaction(s): section to be repeated for 
  4    (i) each type of instrument; (ii) each type of transaction; 
       (iii) each date; and (iv) each place where transactions have 
       been conducted 
     --------------------------------------------------------------------------- 
 a)   Description of the          Ordinary Shares of 1 pence each 
       financial instrument, 
       type of instrument          ISIN: GB00BD5H8572 
       Identification code 
     --------------------------  ----------------------------------------------- 
 b)   Nature of the transaction   Surrender and grant of share options 
     --------------------------  ----------------------------------------------- 
 c)   Price(s) and volume(s)      Options over 50,000 ordinary shares at an 
                                   exercise price of GBP1.70 per share cancelled 
                                   Options over 250,000 ordinary shares at 
                                   an exercise price of 34 pence per share 
                                   granted 
     --------------------------  ----------------------------------------------- 
 d)   Aggregated information      N/A 
       - Aggregated volume 
       - Price 
     --------------------------  ----------------------------------------------- 
 e)   Date of the transaction     19, 20 October 2023 
     --------------------------  ----------------------------------------------- 
 f)   Place of the transaction    Outside a trading venue 
     --------------------------  ----------------------------------------------- 
 
 
      Details of the person discharging managerial responsibilities/person 
  1    closely associated 
 a)   Name                        Matthew Wakefield 
     --------------------------  --------------------------------------------- 
      Reason for the notification 
  2 
     ------------------------------------------------------------------------- 
 a)   Position/status             Director/PDMR 
     --------------------------  --------------------------------------------- 
 b)   Initial notification/       Initial notification 
       Amendment 
     --------------------------  --------------------------------------------- 
      Details of the issuer, emission allowance market participant, 
  3    auction platform, auctioneer or auction monitor 
     ------------------------------------------------------------------------- 
 a)   Name                        Oxford BioDynamics Plc 
     --------------------------  --------------------------------------------- 
 b)   LEI                         2138005Y1TK258O5U928 
     --------------------------  --------------------------------------------- 
      Details of the transaction(s): section to be repeated for 
  4    (i) each type of instrument; (ii) each type of transaction; 
       (iii) each date; and (iv) each place where transactions have 
       been conducted 
     ------------------------------------------------------------------------- 
 a)   Description of the          Ordinary Shares of 1 pence each 
       financial instrument, 
       type of instrument          ISIN: GB00BD5H8572 
       Identification code 
     --------------------------  --------------------------------------------- 
 b)   Nature of the transaction   Grant of share options 
     --------------------------  --------------------------------------------- 
 c)   Price(s) and volume(s)      150,000 ordinary shares at an exercise price 
                                   of 34 pence per share 
     --------------------------  --------------------------------------------- 
 d)   Aggregated information      N/A 
       - Aggregated volume 
       - Price 
     --------------------------  --------------------------------------------- 
 e)   Date of the transaction     20 October 2023 
     --------------------------  --------------------------------------------- 
 f)   Place of the transaction    Outside a trading venue 
     --------------------------  --------------------------------------------- 
 

-Ends-

For further details please contact:

 
 Oxford BioDynamics Plc                                   Tel: +44 (0)1865 
  Jon Burrows, CEO                                                  518910 
  Paul Stockdale, CFO 
 Shore Capital - Nominated Adviser and                      Tel: +44 (0)20 
  Broker                                                         7408 4090 
  Stephane Auton / Iain Sexton 
 Instinctif Partners                                        Tel: +44 (0)20 
  Melanie Toyne-Sewell / Rozi Morris                             7457 2020 
  Adam Loudon / Jack Kincade              OxfordBioDynamics@instinctif.com 
 

Notes for Editors

About Oxford BioDynamics Plc

Oxford BioDynamics Plc (AIM: OBD) is a global biotechnology company, advancing personalized healthcare by developing and commercializing precision medicine tests for life-changing diseases.

Its flagship products are the EpiSwitch(R) CiRT (Checkpoint Inhibitor Response Test) and EpiSwitch(R) PSE (EpiSwitch Prostate Screening test) blood tests. CiRT is a predictive immune response profile for immuno-oncology (IO) checkpoint inhibitor treatments, launched in February 2022. PSE is a blood test that boosts the predictive accuracy of a PSA test from 55% to 94% when testing the presence or absence of prostate cancer, which has been launched in the US and UK in September 2023.

In March 2021, the Company launched its first commercial prognostic test, EpiSwitch(R) CST (Covid Severity Test) and the first commercially available microarray kit for high-resolution 3D genome profiling and biomarker discovery, EpiSwitch(R) Explorer Array Kit , which is available for purchase by the life science research community.

The Company's product portfolio is based on a proprietary 3D genomic biomarker platform, EpiSwitch(R), which can build molecular diagnostic classifiers for the prediction of response to therapy, patient prognosis, disease diagnosis and subtyping, and residual disease monitoring in a wide range of indications.

Oxford BioDynamics has participated in more than 40 partnerships with big pharma and leading institutions including Pfizer, EMD Serono, Genentech, Roche, Biogen, Mayo Clinic, Massachusetts General Hospital and Mitsubishi Tanabe Pharma.

The Company has created a valuable technology portfolio, including biomarker arrays, molecular diagnostic tests, bioinformatic tools for 3D genomics and an expertly curated 3D genome knowledgebase comprising hundreds of millions of data points from over 15,000 samples in more than 30 human diseases.

OBD is headquartered in Oxford, UK and is listed on AIM of the London Stock Exchange. It also has a commercial office in Gaithersburg and a clinical laboratory in Frederick, MD, USA, and a reference laboratory in Penang, Malaysia.

For more information, please visit the Company's website, www.oxfordbiodynamics.com , or follow OBD on Twitter (@OxBioDynamics) and LinkedIn .

About EpiSwitch(R)

The 3D configuration of the genome plays a crucial role in gene regulation. By mapping this architecture and identifying abnormal configurations, EpiSwitch(R) can be used to diagnose patients or determine how individuals might respond to a disease or treatment.

Built on over 10 years of research, EpiSwitch(R) is Oxford Biodynamics' award-winning, proprietary platform that enables screening, evaluation, validation and monitoring of 3D genomic biomarkers. The technology is fully developed, based on testing of over 15,000 samples in 30 disease areas, and reduced to practice.

In addition to stratifying patients with respect to anticipated clinical outcomes, EpiSwitch(R) data offer insights into systems biology and the physiological manifestation of disease that are beyond the scope of other molecular modalities. The technology has performed well in academic medical research settings and has been validated through its integration in biomarker discovery and clinical development with big pharma.

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END

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