Clinical Study Demonstrates BeRelief®'s capabilities in
reducing lingering back ache
MADRID, July 30,
2024 /PRNewswire/ -- Monteloeder, S. L., a subsidiary
of SuanNutra, introduces BeRelief®, an all-natural botanical
composition that addresses musculoskeletal discomfort and helps
support a feeling of well-being. This formulation was created with
the help of machine learning tools and is backed by
research.
BeRelief is a proprietary blend of three botanical extracts:
ashwagandha, rosemary, and sesame. Their active compounds have been
analyzed for their capacity to work synergistically to inhibit the
receptors involved in discomfort. The development of this
ingredient was supported by the Center for Technological
Development and Innovation (CDTI Innovation) and co-financed by the
European Union's FEDER funds.
Machine learning for active ingredients
BeRelief is a result of pioneering research that began with the
preselection of nutrients from a library of 50,000 compounds of
natural origin. The selection process involved deep tech platforms
in a rigorous screening of these phytochemicals based on their
molecular interactions with diverse discomfort receptors. These
include TRPV1, Nav1.7, TrkA, and nAChR which between them play
roles in the transmission of discomfort signals, sensitize neurons
to soreness and influence pain perception.
"In recent years, machine learning has emerged as a key
technology in discovering and developing innovative compounds,"
points out Nuria Caturla, PhD, Chief
R&D Officer of Monteloeder. "We took it one step further,
helping create a nutraceutical that can help us cope with today's
hectic life and improve well-being." The criteria for selection
encompassed specific physicochemical attributes. Following this
selection, the corresponding botanical sources were carefully
obtained and subjected to comprehensive characterization. This
involved a complete analysis of active content, and inherent
traditional properties. BeRelief was developed according to the
complementary and synergistic aspects of different actives.
The Research
The ingredients present in BeRelief have been specifically
selected for their suggested individual and complementary effects
in inhibiting the major channels involved in sensorial transmission
and perception and undergo rigorous quality control.
"Discomfort and soreness can be debilitating and significantly
impact a person's quality of life," explains Maria Ángeles
Gutiérrez Montero, Marketing Director of SuanNutra.
"Developing a natural ingredient can help enhance quality of life
by reducing or alleviating pain. In today's sedentary,
stress-filled, and sleep-deprived lifestyles, discomfort and pain
are increasingly common. Prolonged sitting, repetitive activities,
occasional stress peaks, and lack of sleep can lead to issues like
muscle tension, joint pain, and headaches, which worsen over
time."
A recent randomized double-blind clinical study endorsed the
composition's ability to reduce the intensity of back aches. The
12-week trial led by Silvia Pérez-Piñero, PhD, published in the
Journal Frontiers of Nutrition in June 2024, involved 135 participants who
complained of varying levels of back and neck discomfort. By the
end of the study the two groups on BeRelief experienced significant
and sustained reduction in user-experienced discomfort compared to
the placebo group. The group on the low 400mg per day dose
experienced discomfort reduction by approximately 56%, while those
on the high 800mg dose saw a reduction in aches of about 59% as
recorded on a visual analogue scale (VAS).
Furthermore, BeRelief users reported improvements in
health-related quality of life including enhanced mood and sleep
quality.
"As a research-driven company, we are inspired by nature and
traditional herbal medicine to create botanical solutions that can
help people feel better," asserts Gutiérrez Montero. "We are
combining the wisdom of Eastern botanical medicine with modern
science and 'big data' to support this innovative solution and
provide a holistic approach to total well-being."
The traditional use of ashwagandha for relief is rooted in
Ayurvedic practice, the ancient Indian medical tradition. In
addition to its known uses for improving sleep and its role in
enhancing mood, its potential as a natural discomfort relief and
muscle relaxant is rapidly gaining recognition through clinical
research. Rosemary has been traditionally used in folk medicine for
multiple purposes. It has been used also as a home remedy to
alleviate muscle and joint discomfort, as well as to reduce
occasional headaches. Extracts of sesame have been used in
Traditional Chinese Medicine to help mitigate pain in inflammatory
conditions, while the oil is a traditional medicinal carrier in
Ayurvedic traditions.
About Monteloeder:
Monteloeder contributes cutting-edge innovation and scientific
rigor to the development of botanical health ingredients, featuring
proprietary patented products supported by clinical studies. The
company's portfolio has garnered international accolades in Health
& Wellness, Women's Health, and Beauty from Within.
Monteloeder is a subsidiary of SUANNUTRA, which boasts a rich
heritage of more than 125 years of combined experience in the
European nutraceutical sector.
For more information, contact:
Company contact
Monteloeder, S.L.,
a subsidiary of SuanNutra
Mariana Ortega
Product Manager
E-mail:
info@monteloeder.com
Website: www.suannutra.com
Press Contact
NutriPR
Liat Simha
Tel: +972-9-9742893
E-mail: liat@nutripr.com
Twitter: @NutriPR_
Website: www.nutripr.com
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SOURCE Monteloeder, S.L.