Waters Expands Microscale Separations Science Portfolio
August 17 2016 - 9:00AM
Business Wire
Extending the Practicality and Enhancing the
Value of Microscale Liquid Chromatography, Better Enabling
Scientists to Quantify Hard-to-Separate Analytes in Precious
Samples
Waters Corporation (NYSE: WAT) is unveiling a new line of
chromatographic fittings and a new microscale separations device at
the 21st International Mass Spectrometry Conference. The new
products enable research scientists doing nano-to-microscale liquid
chromatography (LC) to achieve greater levels of productivity for
peptide bioanalyses and for pharmacokinetic and endogenous peptide
biomarker validation studies.
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Waters ionKey/MS microscale
chromatography product portfolio now includes 150 micron i.d. and
300 micron i.d. iKey tiles. (Photo: Business Wire)
High Throughput Microflow LC-MS – Delivering Greater
Analytical Sensitivity in Three Minutes or Less
The Waters® 300-micron i.d. microfluidic device, the iKeyTM HT,
is a new addition to the company’s ionKey/MSTM microscale
chromatography product portfolio. The iKey HT device is a ceramic
tile that is etched with a 300-micron i.d. channel packed with 1.7
or 1.8 micron UPLC® particles, which takes the place of a
traditional capillary column. The larger i.d. microchannel etched
into the new device allows scientists to run separations at higher
flow rates as compared to the 150 micron i.d. tile, thereby
shortening run times to three minutes or less which is comparable
to the run time of a conventional LC separation performed on a 2.1
mm i.d. column.
In a new publication by Waters, the authors describe a study for
which 1,000 injections of a crashed plasma sample containing six
small molecule analytes were run on the same prototype BEH C18 iKey
HT device (300 micron x 50 mm, 1.7 micron). The results showed a
coefficient of variation (% CV) of less than 5%, at least a 2X gain
in sensitivity over UPLC/UHPLC, and a cycle time of less than three
minutes for each sample run.1
The Waters 300 µm I.D. X 50mm (L) iKey HT separation device will
be available with the following separations media: BEH 130Å PsT
C18, 1.7 micron, CSH 130Å PsT C18, 1.7 micron, and HSS T3 100Å, 1.8
micron.
IMSC 2016 attendees will get to hear more about Waters iKey HT
product line at a breakfast seminar on Wednesday, August 24 from 7
– 8 a.m. in Waters hospitality suite #715 at the Metro Toronto
Convention Centre.
The ionKey/MS system, introduced previously by Waters, and which
features a 150 micron iKey, won a top innovation award from The
Analytical Scientist magazine in 2014 and an R&D 100 Award in
2015.
For more information:
http://wvmc.waters.com/imsc/imsc-product-showcase/
New ZenFit Tubing Kits and Finger-Tightened Fittings for
Microscale Chromatography Feature
Good sample preparation is extremely important but never more so
than for nano and micro-scale separations. Despite the best of
intentions, connective tubing inside the UPLC system can clog and
when it does, the remedy is to replace the clogged tubing. For
those less experienced, overtightening of the connective fittings
is common and can lead to breakage or crushing of the tubing.
Waters new ZenFit™ Tubing Kits include finger-tight fittings
featuring ZenFit Connection Technology. Now, with a twist of the
wrist, replacing connective tubing has never been easier.
For more information:
http://wvmc.waters.com/imsc/imsc-product-showcase/
About Waters Corporation (www.waters.com)
Waters Corporation (NYSE:WAT) develops and
manufactures advanced analytical and material science technologies
for laboratory dependent organizations. For more than 50 years, the
company has pioneered a connected portfolio of separations science,
laboratory information management, mass spectrometry and thermal
analysis systems.
Waters, UPLC, ionKey/MS, iKey HT, iKey, ZenFit
and The Science of What’s Possible are trademarks of Waters
Corporation.
1. High Throughput Microflow LC-MS: Sensitivity
Gains on a Practical Timescale, White Paper, July 2016 Part #
720005765EN
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version on businesswire.com: http://www.businesswire.com/news/home/20160817005234/en/
Waters CorporationBrian J. Murphy, +1 508-482-2614Public
Relations Managerbrian_j_murphy@waters.com
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