News Summary:
- Reduces sample volume requirements by 25x through use of
advanced microfluidic technologies while increasing throughput up
to 24x compared with competitor capillary DSC
technologiesi.
- Streamlines thermal stability testing of biologics using
disposable microfluidic chips (MFCs) enabling analysis under actual
high-concentration drug dosing and use conditions.
- Delivers faster and more accurate measurements of
high-concentration biological drug formulationsii with
unique design that simplifies sample preparation and accelerates
drug development.
MILFORD,
Mass., July 23, 2024 /PRNewswire/ -- Waters
Corporation (NYSE: WAT) announced today the global release of the
TA Instruments™ Rapid Screening-Differential Scanning Calorimeter
(TA Instruments RS-DSC), designed for biopharmaceutical developers.
The TA Instruments RS-DSC is a high-throughput DSC for precise
thermal stability testing of high-concentration biologic
formulations specifically for antibody drugs and engineered
proteins.
The TA Instruments RS-DSC offers a more
convenient and accurate solution to assess biological drug
stability and quality
"Demand is increasing for higher concentration injectable drugs,
and biologic developers are looking for stability testing that is
fast and efficient," said Jianqing
Bennett, Waters Corporation Senior Vice President of the TA
Instruments Division. "Our new Rapid Screening-DSC meets these
needs by providing a high-throughput alternative to existing
capillary DSCs and a more reliable and accurate option to
differential scanning fluorescence (DSF) technologies."
The TA Instruments RS-DSC offers a more convenient and accurate
solution to assess biological drug stability and quality by
employing disposable, low sample volume microfluidic chips (MFCs)
that enable up to 24 simultaneous measurements. This reduces or
eliminates the need for sample dilution, repetitive instrument
cleaning, and lowers contamination risk. Its unique design avoids
the sensitivity challenges of DSF methods, enabling it to produce
more accurate dataiii on high-concentration samples.
Additionally, the TA Instruments RS-DSC features
state-of-the-art automated software that provides rapid,
effortless, precise, and in-depth insights about a sample's
thermodynamic properties.
The TA Instruments RS-DSC is now available globally to all
customers through the TA Instruments Division of Waters
Corporation.
Additional Resources
- Learn more about the TA Instruments Rapid
Screening-Differential Scanning Calorimeter
- TA Instruments Rapid Screening-DSC Application Notes:
- Rapid Thermal Stability Screening of High Concentration
Biologic Drugs
- Rapid Thermal Stability Screening and Selection of
Monoclonal Antibody Drug Products
- Follow and connect with the Waters TA Instruments Division via
LinkedIn, Twitter/X, and Facebook
About Waters Corporation (www.waters.com)
Waters Corporation (NYSE:WAT), a global leader in
analytical instruments and software, has pioneered chromatography,
mass spectrometry, and thermal analysis innovations serving the
life, materials, food, and environmental sciences for more than 65
years. With approximately 7,700 employees worldwide, Waters
operates directly in 35 countries, including 15 manufacturing
facilities, and with products available in more than 100
countries.
|
Waters and TA
Instruments are trademarks of Waters Technologies
Corporation.
|
Contact:
Laura Borland, TA Instruments
Corporate Communications
Waters Corporation
laura_borland@waters.com
+1.302.367.6958
|
i As
compared to capillary DSC offered by a leading in-market
competitor. Comparison based on published specifications – the
TA Instruments RS-DSC can perform 24 test runs for every one run on
the competing capillary DSC instrument, which also operates at a
nearly 25x higher sample volume (250 uL) over that of the TA
Instruments RS-DSC (11uL).
ii Compared to differential scanning fluorescence (DSF),
whose sensor can become saturated at high concentrations.
iii Compared to differential scanning fluorescence
(DSF), whose sensor can become saturated at high
concentrations.
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SOURCE Waters Corporation
