TIDMAMYT

RNS Number : 9132Z

Amryt Pharma PLC

22 May 2019

22 May 2019

AIM: AMYT

Euronext Growth: AYP

Amryt Pharma plc

("Amryt" or the "Company")

Grant of Options and Notification of Transactions by Persons Discharging Managerial Responsibilities

Amryt announces that the Remuneration Committee has approved the grant of 3,407,734 share options ("Options") to subscribe for ordinary shares of 1p each in the Company ("Shares") under the Employee Share Option Plan 2016 (the "Plan") to Joe Wiley, CEO, and Rory Nealon, CFO, details of which are set out in the table below.

The Options have an exercise price of 12.64p ("Exercise Price"). These options may be exercised as follows:

 
 --   25% of the total Options granted may be exercised 12 months 
       after the date of grant; 
 --   a further 25% of the total Options granted may be exercised 
       24 months after the date of grant; and 
 --   the balance of the Options may be exercised 36 months 
       after the date of grant. 
 

All Options are subject to change of control provisions and expire on the seventh anniversary of their grant.

Following the grants of these options, the following Directors have the following options:

 
   Director     Options granted   Total Options now 
                                         held 
 Joe Wiley         1,896,239          3,957,369 
               ----------------  ------------------ 
 Rory Nealon       1,511,495          2,335,947 
               ----------------  ------------------ 
 

PDMR Dealings

The notification of dealing forms for each Director can be found below. This announcement is made in accordance with Article 19 of the EU Market Abuse Regulation 596/2014.

 
 1.    Details of the person discharging managerial responsibilities 
        / person closely associated 
 a)    Name                                   Joe Wiley 
      -------------------------------------  ----------------------------------------------- 
 2.    Reason for the notification 
      -------------------------------------------------------------------------------------- 
 a)    Position / status                      Director 
      -------------------------------------  ----------------------------------------------- 
 b)    Initial notification                   Initial notification 
        / amendment 
      -------------------------------------  ----------------------------------------------- 
 3.    Details of the issuer, emission allowance market participant, 
        auction platform, auctioneer or auction monitor 
      -------------------------------------------------------------------------------------- 
 a)    Name                                   Amryt Pharma plc 
      -------------------------------------  ----------------------------------------------- 
 b)    Legal entity identifier                213800BOS8WAJO2BEQ38 
      -------------------------------------  ----------------------------------------------- 
 4.    Details of the transaction(s): section to be repeated 
        for (i) each type of instrument; (ii) each type of 
        transaction; (iii) each date; and (iv) each place 
        where transactions have been conducted 
      -------------------------------------------------------------------------------------- 
 a)    Description of the                     Ordinary shares of GBP0.01 each 
        financial instrument, 
        type of instrument 
       Identification code                    ISIN: GB00BDD1LS57 
      -------------------------------------  ----------------------------------------------- 
 b)    Nature of the transaction              Grant of options under the Employee 
                                               Share Option Plan 2016 with an exercise 
                                               price of 12.64p to purchase 1,896,239 
                                               ordinary shares. 
      -------------------------------------  ----------------------------------------------- 
 c)    Currency                               British Pounds 
      -------------------------------------  ----------------------------------------------- 
 d)    Price(s) and volume(s)                  Price(s)                Volume(s) 
      -------------------------------------   ----------------------  -------------------- 
    N/A                                                                1,896,239 
   -----------------------------------------------------------------  -------------------- 
 e)    Aggregated information 
         *    Aggregated volume                 1,896,239 
                                                N/A 
 
         *    Aggregated price 
      -------------------------------------  ----------------------------------------------- 
 f)    Date of the transaction                21 May 2019 
      -------------------------------------  ----------------------------------------------- 
 g)    Place of the transaction               Outside a trading venue 
      -------------------------------------  ----------------------------------------------- 
 
 
 1.    Details of the person discharging managerial responsibilities 
        / person closely associated 
 a)    Name                                   Rory Nealon 
      -------------------------------------  ----------------------------------------------- 
 2.    Reason for the notification 
      -------------------------------------------------------------------------------------- 
 a)    Position / status                      Director 
      -------------------------------------  ----------------------------------------------- 
 b)    Initial notification                   Initial notification 
        / amendment 
      -------------------------------------  ----------------------------------------------- 
 3.    Details of the issuer, emission allowance market participant, 
        auction platform, auctioneer or auction monitor 
      -------------------------------------------------------------------------------------- 
 a)    Name                                   Amryt Pharma plc 
      -------------------------------------  ----------------------------------------------- 
 b)    Legal entity identifier                213800BOS8WAJO2BEQ38 
      -------------------------------------  ----------------------------------------------- 
 4.    Details of the transaction(s): section to be repeated 
        for (i) each type of instrument; (ii) each type of 
        transaction; (iii) each date; and (iv) each place 
        where transactions have been conducted 
      -------------------------------------------------------------------------------------- 
 a)    Description of the                     Ordinary shares of GBP0.01 each 
        financial instrument, 
        type of instrument 
       Identification code                    ISIN: GB00BDD1LS57 
      -------------------------------------  ----------------------------------------------- 
 b)    Nature of the transaction              Grant of options under the Employee 
                                               Share Option Plan 2016 with an exercise 
                                               price of 12.64p to purchase 1,511,495 
                                               ordinary shares. 
      -------------------------------------  ----------------------------------------------- 
 c)    Currency                               British Pounds 
      -------------------------------------  ----------------------------------------------- 
 d)    Price(s) and volume(s)                  Price(s)                Volume(s) 
      -------------------------------------   ----------------------  -------------------- 
    N/A                                                                1,511,495 
   -----------------------------------------------------------------  -------------------- 
 e)    Aggregated information 
         *    Aggregated volume                 1,511,495 
                                                N/A 
 
         *    Aggregated price 
      -------------------------------------  ----------------------------------------------- 
 f)    Date of the transaction                21 May 2019 
      -------------------------------------  ----------------------------------------------- 
 g)    Place of the transaction               Outside a trading venue 
      -------------------------------------  ----------------------------------------------- 
 

Enquiries:

 
 Amryt Pharma plc                        +353 (1) 518 0200 
 Joe Wiley, CEO 
  Rory Nealon, CFO/COO 
 
   Shore Capital                         +44 (0) 20 7408 4090 
 Financial Advisor, NOMAD and Joint 
  Broker 
 Edward Mansfield, Mark Percy, Daniel 
  Bush 
 Stifel                                  +44 (0) 20 7710 7600 
 Joint Broker 
 Jonathan Senior, Ben Maddison 
 
   Davy                                  +353 (1) 679 6363 
 Euronext Growth Advisor and Joint 
  Broker 
 John Frain, Daragh O'Reilly 
 Consilium Strategic Communications      +44 (0) 20 3709 5700 
 Amber Fennell, Matthew Neal, David 
  Daley 
 

About Amryt

Amryt is a biopharmaceutical company focused on developing and delivering innovative new treatments to help improve the lives of patients with rare or orphan diseases.

Lojuxta(R) is an approved treatment for adult patients with the rare cholesterol disorder - Homozygous Familial Hypercholesterolaemia ("HoFH"). This disorder impairs the body's ability to remove low density lipoprotein ("LDL") cholesterol ("bad" cholesterol) from the blood, typically leading to abnormally high blood LDL cholesterol levels in the body from before birth - often ten times more than people without HoFH - and subsequent aggressive and premature narrowing and blocking of blood vessels. Lojuxta(R) is indicated as an adjunct to a low-fat diet and other lipid-lowering medicinal products with or without LDL apheresis in adult patients with HoFH.

Amryt is the marketing authorisation holder and has an exclusive licence to sell Lojuxta(R) (lomitapide) across the European Economic Area, Middle East and North Africa, Switzerland, Turkey, Israel, Russia, the Commonwealth of Independent States and the non-EU Balkan states.

Amryt's lead development candidate, AP101, is a potential treatment for Epidermolysis Bullosa ("EB"), a rare and distressing genetic skin disorder affecting young children and adults for which there is currently no treatment. It is currently in Phase 3 clinical trials and recently reported positive unblinded interim efficacy analysis results and is anticipated will be fully enrolled by end of H2 2019. The European and US market opportunity for EB is estimated to be in excess of $1 billion.

In March 2018, Amryt in-licenced a pre-clinical gene-therapy platform technology, AP103, which offers a potential treatment for patients with Recessive Dystrophic Epidermolysis Bullosa, a subset of EB, and is also potentially relevant to other genetic disorders.

In May 2019, Amryt announced the planned acquisition of Aegerion Pharmaceuticals. This Transaction will put Amryt on the path to creating a rare and orphan disease company with a diversified offering of multiple commercial and development stage assets and will provide it with scale to support further growth. The Transaction will give Amryt an expanded commercial footprint to market two US and EU approved products, lomitapide (Juxtapid(R) (US/ROW) / Lojuxta(R) (EU)) and metreleptin (Myalept(R) (US) / Myalepta(R) (EU)). Amryt's leadership team already has a deep knowledge of both these products and since December 2016 has successfully commercialized Lojuxta(R) across Europe and the Middle East.

For more information on Amryt, please visit www.amrytpharma.com.

This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact rns@lseg.com or visit www.rns.com.

END

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