RNS Number:6019L
Alizyme PLC
28 May 2003


Immediate Release                                                  28 May 2003


                                  ALIZYME PLC


                   NOTIFICATION OF MAJOR INTERESTS IN SHARES


Cambridge, UK, 28 May 2003: Alizyme plc (London Stock Exchange: AZM) announces
that it received, yesterday, the following notification under Companies Act 1985
ss.198-202 (as amended), from Hg Pooled Management Limited.


"Companies Act 1985 ss. 198-202

Disclosure Of Interests In Shares


Pursuant to the above provisions we hereby notify you on behalf of our client of
the following change of interest in shares of your Company.


As at 15th May 2003 the interest is as follows:

Name of Client:                                 HGT L.P.

Class of Shares:                                Ordinary

Sale/Purchase:                                  Transfer in

Holding:                                        8,824,575

Level of Interest:                              6.5%"



For further information, please contact:
Mr Tim McCarthy, Finance Director
Alizyme plc                                       Tel No: + 44(0)1223 896000

Lisa Baderoon
Buchanan Communications                           Tel No: + 44(0)20 7466 5000


Further information on Alizyme can be found on the Company's website:
www.alizyme.com







                      This information is provided by RNS
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