Exhibit A

JOINT FILING AGREEMENT

The undersigned agree that this Schedule 13G Amendment No. 4 dated February 14, 2025 relating to the Common Stock, $0.001 par value, of Syros Pharmaceuticals, Inc. shall be filed on behalf of the undersigned.

 

AVIDITY PARTNERS MANAGEMENT LP

By Avidity Partners Management (GP) LLC, its general partner

 

By: /s/ Michael Gregory

  Title: Managing Member

 

 

 

AVIDITY PARTNERS MANAGEMENT (GP) LLC

 

By: /s/ Michael Gregory

  Title: Managing Member

 

 

 

AVIDITY CAPITAL PARTNERS FUND (GP) LP

By Avidity Capital Partners (GP) LLC, its general partner

 

By: /s/ Michael Gregory

  Title: Managing Member

 

 

 

AVIDITY CAPITAL PARTNERS (GP) LLC

 

By: /s/ Michael Gregory

  Title: Managing Member

 

 

 

AVIDITY MASTER FUND LP

By Avidity Capital Partners Fund (GP) LP, its general partner

By: Avidity Capital Partners (GP) LLC, its general partner

 

By: /s/ Michael Gregory

  Title: Managing Member

 

 

 

AVIDITY PRIVATE MASTER FUND I LP

By Avidity Capital Partners Fund (GP) LP, its general partner

By: Avidity Capital Partners (GP) LLC, its general partner

 

By: /s/ Michael Gregory

  Title: Managing Member

 

 

 

DAVID WITZKE

 

By: /s/ David Witzke

 

 

 

MICHAEL GREGORY

 

By: /s/ Michael Gregory

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