BriaCell Adds Mary Crowley Cancer Research Center as a Clinical Trial Site for its Phase I/IIa Breast Cancer Study
November 18 2021 - 8:00AM
BriaCell Therapeutics Corp. (Nasdaq: BCTX, BCTXW)
(TSX-V:BCT) (“BriaCell” or the “Company”), a
clinical-stage biotechnology company specializing in targeted
immunotherapies for advanced breast cancer and other cancers,
announces that Mary Crowley Cancer Research center in Dallas, Texas
is now actively screening and enrolling advanced breast cancer
patients in the Phase I/IIa combination study of BriaCell’s lead
candidate, Bria-IMT™, with Incyte’s checkpoint inhibitors,
retifanlimab and epacadostat.
Dr. Minal Barve, the
Executive Medical Director and Chief Medical Officer for Mary
Crowley Cancer Research center and Board-Certified in medical
oncology and internal medicine, will act as the clinical site’s
Principal Investigator. Dr. Barve will work closely with Cancer
Insight, LLC to manage the clinical and regulatory aspects of the
Phase I/IIa clinical trial in advanced breast cancer on behalf of
BriaCell.
In addition to Mary
Crowley Cancer Research center, the clinical sites at St. Joseph
Health-Sonoma County, Santa Rosa, Calif. and the Cancer Center of
Kansas, Wichita, Kan. are open and actively enrolling patients for
BriaCell’s Phase I/IIa advanced breast cancer clinical trial.
“We look forward to
supporting BriaCell’s efforts to develop safe and effective
therapeutics for advanced breast cancer patients with few, if any,
treatment options,” stated Dr. Barve.
“We are delighted to
add Mary Crowley Cancer Research center with Dr. Barve as Principal
Investigators to our team. Dr. Barve’s leading knowledge and
experience in biological therapies and immunotherapies for cancer
will be highly valuable to us. We look forward to working with her
team in our advanced breast cancer clinical trial to accelerate
patient recruitment,” stated Dr. Williams, BriaCell’s President and
CEO.
BriaCell anticipates the addition of the Mary
Crowley Cancer Research center clinical sites may accelerate
patient enrolment to build on our existing patient data. BriaCell
had previously reported 12.0 months average overall survival in
advanced breast cancer patients in its Phase I/IIa combination
study including 13.4 months in patients with 2+ HLA matches and
12.5 months in patients with Grade I/II tumors, compared with
7.2-9.8 months survival in historical comparison treatment studies.
The top responder patient showed 21.4 months survival plus 100%
resolution of ‘eye-bulging’ orbital tumor.
Founded by Dallas
entrepreneur Mary C. Crowley and her fundamental belief that cancer
patients needed access to better cancer treatments, Mary Crowley
Cancer Research center was established in 1997 to provide
potentially curative treatments for adult cancer patients. Mary
Crowley Cancer Research center’s mission is to bring hope to cancer
patients through innovative clinical trials, while advancing
treatment for patients in the future.
About BriaCell
Therapeutics Corp.
BriaCell is an immuno-oncology focused
biotechnology company developing targeted and effective approaches
for the management of cancer. More information is available at
https://briacell.com/.
Safe Harbor
This press release contains “forward-looking
statements” that are subject to substantial risks and
uncertainties. All statements, other than statements of historical
fact, contained in this press release are forward-looking
statements. Forward-looking statements contained in this press
release may be identified by the use of words such as “anticipate,”
“believe,” “contemplate,” “could,” “estimate,” “expect,” “intend,”
“seek,” “may,” “might,” “plan,” “potential,” “predict,” “project,”
“target,” “aim,” “should,” "will” “would,” or the negative of these
words or other similar expressions, although not all
forward-looking statements contain these words. Forward-looking
statements are based on BriaCell’s current expectations and are
subject to inherent uncertainties, risks and assumptions that are
difficult to predict. Further, certain forward-looking statements
are based on assumptions as to future events that may not prove to
be accurate. These and other risks and uncertainties are described
more fully under the heading "Risks and Uncertainties" in the
Company's most recent Management’s Discussion and Analysis, under
“Risks and Uncertainties” in the Company's other filings with the
Canadian securities regulatory authorities and the U.S. Securities
and Exchange Commission, all of which are available under our
profiles on SEDAR at www.sedar.com and on EDGAR at
www.sec.gov. Forward-looking statements contained
in this announcement are made as of this date, and BriaCell
Therapeutics Corp. undertakes no duty to update such information
except as required under applicable law.
Neither TSX Venture Exchange nor its Regulation Services
Provider (as that term is defined in the policies of the TSX
Venture Exchange) accepts responsibility for the adequacy or
accuracy of this release.
Contact Information
Company Contact:William V. Williams,
MDPresident & CEO1-888-485-6340info@briacell.com
Media Relations:Jules AbrahamDirector of Public
RelationsCORE IR917-885-7378julesa@coreir.com
Investor Relations Contact:CORE
IRinvestors@briacell.com
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