FORM 3
        
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Bartel Ronnda

2. Date of Event Requiring Statement (MM/DD/YYYY)
8/25/2010 

3. Issuer Name and Ticker or Trading Symbol

AASTROM BIOSCIENCES INC [ASTM]

(Last)        (First)        (Middle)

PO BOX 376

4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                            _____ 10% Owner
___ X ___ Officer (give title below)          _____ Other (specify below)
Chief Scientific Officer /

(Street)

ANN ARBOR, MI 48106       

(City)              (State)              (Zip)
5. If Amendment, Date Original Filed (MM/DD/YYYY)

8/27/2010 

6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person


Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4) 		2. Amount of Securities Beneficially Owned
(Instr. 4) 		3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5) 		4. Nature of Indirect Beneficial Ownership
(Instr. 5)

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 4) 		2. Date Exercisable and Expiration Date
(MM/DD/YYYY) 		3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4) 		4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5) 		6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (right to buy)   (1)   (1) 10/16/2016   Common Stock   31250   $10.88   D    
Stock Option (right to buy)   (2)   (2) 9/6/2017   Common Stock   8787   $8.96   D    
Stock Option (right to buy)   (3)   (3) 11/30/2017   Common Stock   3350   $7.36   D    
Stock Option (right to buy)   (4)   (4) 10/31/2018   Common Stock   31250   $3.20   D    
Stock Option (right to buy)   (5)   (5) 7/31/2019   Common Stock   31250   $3.20   D    
Stock Option (right to buy)   (6)   (6) 4/23/2020   Common Stock   90000   $1.80   D    

Explanation of Responses:
( 1)  These options were omitted from the reporting person's original Form 3. These options were granted on October 16, 2006 and vest over a period of four years, with 25% vesting on the first anniversary of the date of grant and 6.25% vesting each quarter thereafter.
( 2)  These options were omitted from the reporting person's original Form 3. These options were granted on September 6, 2007 and vest over a period of four years, with 25% vesting on the first anniversary of the date of grant and 6.25% vesting each quarter thereafter.
( 3)  These options were omitted from the reporting person's original Form 3. These options were granted on November 30, 2007 and vest over a period of four years, with 25% vesting on the first anniversary of the date of grant and 6.25% vesting each quarter thereafter.
( 4)  These options were omitted from the reporting person's original Form 3. These options were granted on October 31, 2008 and vest over a period of four years, with 25% vesting on the first anniversary of the date of grant and 6.25% vesting each quarter thereafter.
( 5)  These options were omitted from the reporting person's original Form 3. These options were granted on July 31, 2009 and vest over a period of four years, with 25% vesting on the first anniversary of the date of grant and 6.25% vesting each quarter thereafter.
( 6)  These options were omitted from the reporting person's original Form 3. These options were granted on April 23, 2010 and vest quarterly over four years commencing on the date of grant.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
Bartel Ronnda
PO BOX 376
ANN ARBOR, MI 48106

Chief Scientific Officer

Signatures
/s/ Scott Durbin, attorney-in-fact 9/3/2010
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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