Bruker Announces Three New GHz NMR Systems Orders for Functional Structural Biology and Clinical Phenomics Research
July 11 2022 - 5:00AM
Business Wire
Three Labs in Japan and Spain to Receive
Novel Compact Ascend Evo 1.0 GHz Magnets
At the Euromar 2022 Conference, Bruker announced three new
customer orders for GHz systems, which will incorporate novel,
compact 1.0 GHz NMR magnets for structural biology applications and
clinical research in single-story laboratories. The new Ascend
Evo 1.0 GHz NMR magnet, operating at 4.2 Kelvin, allows
functional structural biology and clinical phenomics researchers to
dive deeper into the structural details, binding and dynamics of
molecular structures and complexes for fundamental cell biology and
pathobiology research. It complements Bruker’s Avance Neo 1.1 GHz
and 1.2 GHz NMR systems with two-story 2 Kelvin magnets, which
typically are used at shared national NMR facilities, such as the
1.2 GHz NMR at the Dutch Ultra-high Field Magnetic Resonance
Consortium, operating at Utrecht University.
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Compact 1.0 GHz NMR magnet Ascend Evo for
structural biology applications and clinical research in
single-story laboratories (Graphic: Business Wire)
A first new 1.0 GHz NMR order comes from the RIKEN Center for
Biosystems Dynamics Research in Yokohama, Japan. The RIKEN team
under Dr. Ichio Shimada will use GHz NMR to study dynamical
structures of biomolecules in solution and to investigate the
relationships between dynamical structures and biological function
or pathobiology.
Bruker also confirms two 1.0 GHz NMR orders from major research
centers and universities in Bilbao and Barcelona, both in Spain,
for clinical and biological research:
Professor Óscar Millet, Principal Investigator of the Precision
Medicine and Metabolism Lab at CIC bioGUNE stated: “The Ascend
Evo 1.0 GHz will advance our research in clinical metabolomics.
This novel magnet provides highest-resolution NMR to investigate
the molecular patterns and mechanism of action of prevalent and
rare diseases in precision medicine, all in a single-story lab and
with a smaller footprint.”
Professor Miquel Pons Valles, Group Leader of the BioNMR Group
at Universitat de Barcelona and his team use biophysical methods,
especially NMR, as well as chemical biology, molecular biology, and
computations to study proteins in regulatory processes, where
dynamics is essential for function. The Ascend Evo 1.0 GHz will
also advance their research on intrinsically disordered proteins
(IDPs).
The recently introduced, compact Ascend Evo 1.0 GHz NMR
magnet has significantly reduced footprint, weight, and ceiling
height requirements to fit into most single-story laboratories.
Along with a 65% reduction in helium consumption, this provides
more structural biology principal investigators, individual
universities and research centers, as well as advanced biopharma
companies access to the sensitivity and resolution of GHz NMR in
order to enable new research capabilities.
Another innovation is Bruker’s new Heliosmart Recovery, a
compact and easy-to-site system that collects helium boil-off from
NMR magnets. Helium gas is stored in high-pressure cylinders, which
can be used by cryogen suppliers for reliquification. The
Heliosmart Recovery system can collect the steady-state boil-off of
several NMR magnets in parallel with typical recovery rates of 80%
– 85%.
Dr. Falko Busse, President of the Bruker BioSpin Group,
commented: "We are excited to announce the three new GHz orders,
which will incorporate our innovative, single-story Ascend Evo 1.0
GHz magnet. This technological marvel brings the power of GHz NMR
to more laboratories due to its smaller footprint, reduced
maintenance requirements and lower Helium consumption.”
Please join Bruker at Euromar at our booth for interaction with
our NMR and EPR teams.
About Bruker Corporation (Nasdaq: BRKR)
Bruker is enabling scientists to make breakthrough discoveries
and develop new applications that improve the quality of human
life. Bruker’s high performance scientific instruments and high
value analytical and diagnostic solutions enable scientists to
explore life and materials at molecular, cellular and microscopic
levels. In close cooperation with our customers, Bruker is enabling
innovation, improved productivity and customer success in life
science molecular and cell biology research, in applied and pharma
applications, in microscopy and nanoanalysis, as well as in
industrial applications. Bruker offers differentiated, high-value
life science and diagnostics systems and solutions in preclinical
imaging, clinical phenomics research, proteomics and multiomics,
spatial and single-cell biology, functional structural and
condensate biology, as well as in clinical microbiology and
molecular diagnostics. For more information, please visit:
www.bruker.com.
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