Filed pursuant to Rule 424(b)(3)​

 Registration No. 333-278468

 

PROSPECTUS SUPPLEMENT

(To Prospectus Dated April 30, 2024)

 

Up to 5,497,506 Common Shares

 

Offered by the Selling Stockholders

 

 

 

This prospectus supplement supplements the information contained in the prospectus dated April 30, 2024 (the “Prospectus”), which forms a part of our Registration Statement on Form S-3 (Registration No. 333-278468) (the “Registration Statement”), relating to the offer and resale, from time to time, by the selling stockholders (the “Selling Stockholders”) named in the Prospectus of our common shares, no par value per share (our “common shares”).

 

This prospectus supplement should be read in conjunction with the Prospectus. If there is any inconsistency between the information in the Prospectus and this prospectus supplement, you should rely on the information in this prospectus supplement. This prospectus supplement is not complete without, and may not be delivered or utilized except in connection with, the Prospectus, including any amendments or supplements thereto. Capitalized terms used in this prospectus supplement and not otherwise defined herein have the meanings set forth in the Prospectus.

 

We are filing this prospectus supplement pursuant to that certain exchange agreement, dated October 17, 2024, by and among us and certain of the Selling Stockholders (the “Share Exchange”) to reflect the cancellation of certain of the common shares registered for resale under the Registration Statement, as well as to update the information contained in the section of the Prospectus entitled “Selling Stockholders” to reflect the Share Exchange. For more information regarding the Share Exchange, please see the Current Report on Form 8-K filed by us on October 17, 2024.

 

The following table has also been revised to update the holdings of the Selling Stockholders as of the date of this prospectus supplement. The table, including the footnotes, set forth under the caption “Selling Stockholders” in the Prospectus is hereby replaced in its entirety by the below table.

 

The number of common shares beneficially owned by each Selling Stockholder in the table below is based on information supplied to us by each such Selling Stockholder, with beneficial ownership determined in accordance with the rules and regulations of the SEC and includes voting or investment power with respect to the common shares. This information does not necessarily indicate beneficial ownership for any other purpose. The percentage of beneficial ownership is based on 73,331,690 common shares outstanding as of October 21, 2024.

 

  

Common Shares Beneficially
Owned
Prior to Offering

      

Common Shares Beneficially
Owned
After Offering

 
Selling Stockholder  Number of
Common
Shares		   Percentage of
Outstanding
Common
Shares		   Number of
Common Shares
Registered for
Sale Hereby		   Number of
Common
Shares		   Percentage of
Outstanding
Common
Shares		 
Deep Track Biotechnology Master Fund, LTD(1)   7,065,099    9.14%   2,666,667    4,398,432    5.69%
Commodore Capital Master LP(2)   7,694,963    9.99%   1,833,333    7,595,442    9.64%
K2 HealthVentures Equity Trust LLC(3)   997,506    1.34%   997,506    —    — 

 

 

 

 

 

(1)The number of shares beneficially owned prior to and after this offering includes 4,000,000 common shares underlying a warrant for common shares owned by this Selling Stockholder. Under the terms of such warrant, the holder may not exercise the warrant to the extent such exercise would cause such holder, together with its affiliates, to beneficially own a number of common shares which would exceed 9.99% of the number of common shares outstanding following such exercise (the “Ownership Cap”). Upon 61 days’ advance written notice to us, the holder of such warrant may from time to time increase or decrease the Ownership Cap percentage up to 19.99%. Deep Track Capital, LP (the “Deep Track Investment Manager”) serves as the investment manager to Deep Track Biotechnology Master Fund Ltd. (the “Deep Track Master Fund”) and may be deemed to beneficially own such shares. Deep Track Capital GP, LLC (the “Deep Track General Partner”) is the General Partner of the Deep Track Investment Manager. David Kroin is the Chief Investment Officer of the Deep Track Investment Manager and managing member of the Deep Track General Partner and may be deemed to beneficially own such shares. The business address of the Deep Track Master Fund, the Deep Track Investment Manager, the Deep Track General Partner and Mr. Kroin is 200 Greenwich Avenue, 3rd Floor, Greenwich, CT 06830.

 

(2)The number of shares beneficially owned prior to this offering includes 3,694,963 common shares underlying warrants for common shares owned by this Selling Stockholder. Under the terms of such warrants, the holder may not exercise the warrants to the extent such exercise would cause such holder, together with its affiliates, to beneficially own a number of common shares which would exceed the Ownership Cap. Upon 61 days’ advance written notice to us, the holder of such warrants may from time to time increase or decrease the Ownership Cap percentage up to 19.99%. The number of shares beneficially owned prior to this offering does not include 1,733,812 common shares underlying such warrants as a result of the Ownership Cap and the 61 days’ advance notice provision. The number of shares beneficially owned after this offering includes 5,428,775 common shares underlying such warrants for common shares owned by this Selling Stockholder. Commodore Capital LP is the investment manager to Commodore Capital Master LP and may be deemed to beneficially own the shares held by Commodore Capital Master LP. Michael Kramarz and Robert Egen Atkinson are the managing partners of Commodore Capital LP and exercise investment discretion with respect to these shares. Commodore Capital LP and Commodore Capital Master LP have shared voting and dispositive power with respect to these shares. The address of Commodore Capital LP and Commodore Capital Master LP is 444 Madison Avenue, 35th Floor, New York, NY 10022.

 

(3)Consists of up to 997,506 common shares issuable upon the conversion by the Lenders of any portion of the principal amount of the Term Loan up to an aggregate principal amount of $4.0 million, then outstanding under the Loan Agreement. Parag Shah and Anup Arora serve as the managing members of K2 HealthVentures LLC, the sole member of K2 HealthVentures Equity Trust LLC, and in such capacities may be deemed to indirectly beneficially own the shares beneficially owned by K2 HealthVentures Equity Trust LLC. The address of K2 HealthVentures LLC and K2 HealthVentures Equity Trust LLC is 855 Boylston Street, Suite 1000, Boston, MA 02116.

 

 

 

Investing in our common shares involves a high degree of risk. See “Risk Factors” on page 9 of the Prospectus and in the documents incorporated by reference into the Prospectus.

 

Neither the Securities and Exchange Commission nor any state or other securities commission has approved or disapproved of the common shares offered in the Prospectus or determined if the Prospectus or this prospectus supplement is truthful or complete. Any representation to the contrary is a criminal offense.

 

The date of this prospectus supplement is October 22, 2024.

 

 

 

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