In this free webinar, learn the methodological considerations
involved in using real-world comparator cohorts (RWCCs) in clinical
trials. Attendees will learn strategies for designing and
conducting robust RWCC studies that minimize bias and confounding.
The featured speaker will discuss how to leverage real-world data
to generate high-quality evidence for clinical decision-making.
TORONTO, July 31,
2024 /PRNewswire-PRWeb/ -- Real-world comparator
cohorts (RWCC) are increasingly being used in clinical trials as
synthetic controls particularly in rare and complex disease
populations and in settings where randomized controlled trials
(RCTs) are infeasible or unethical. While RWCCs offer potential
benefits such as increased efficiency, reduced costs and improved
generalizability, their use also raises methodological
challenges.
While RWCCs offer potential benefits such
as increased efficiency, reduced costs and improved
generalizability, their use also raises methodological
challenges.
This webinar will delve into methodological considerations
surrounding the use of RWCCs in clinical trials, covering topics
such as:
- Role in Clinical Research: Reviewing the
importance/applications of RWCCs in clinical research
- Study Design: How to select appropriate RWCCs, considering
factors such as data source, inclusion/exclusion criteria and
potential biases
- Data Sources: Understanding the strengths and limitations of
different real-world data sources, including electronic health
records, claims data and patient registries and explore approaches
for pooling data from various sources
- Statistical Analysis: Exploring appropriate statistical methods
for analyzing RWCC data, including propensity score matching,
regression adjustment and instrumental variable analysis
- Bias and Confounding: Identifying and addressing potential
sources of bias and confounding in RWCC studies such as selection
bias, measurement error and unmeasured confounding
- Case Example: Examine a real-world example of successful use of
RWCCs in clinical trials, highlighting best practices and lessons
learned
Register now for this webinar focusing on the use of real-world
comparator cohorts in clinical trials and their growing role in
research.
Join Kitty Rajagopalan, PhD,
President & Chief Scientific Officer, Anlitiks, for the live
webinar on Thursday, August 22, 2024,
at 12pm EDT (6pm CEST/EU-Central).
For more information, or to register for this event, visit
Leveraging Real-World Comparator Cohorts in Clinical Trials: A
Methodological Deep Dive.
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