AIM Doses First New Subject in Phase 2 Study of Ampligen and Imfinzi as a Potential Combination Therapy for Late-Stage Pancreatic Cancer
February 25 2025 - 7:30AM
AIM ImmunoTech Inc. (NYSE American:
AIM) (“AIM” or the “Company”) today announced that
the first new subject has been dosed in Phase 2 of the Phase 1b/2
clinical trial involving AIM’s Ampligen (rintatolimod) and
AstraZeneca’s anti-PD-L1 immune checkpoint inhibitor Imfinzi®
(durvalumab) in the treatment of late-stage pancreatic cancer
(“DURIPANC”). Several subjects from Phase 1 who received the
highest dose will also be included in Phase 2.
DURIPANC is an investigator-initiated,
exploratory, open-label, single-center study in the Netherlands at
the Erasmus Medical Center. Up to 25 patients are expected to be
enrolled in the Phase 2 portion of DURIPANC.
AIM CEO Thomas K. Equels stated: “Unlike with
many pancreatic cancer studies where accrual can be a major
obstacle, we expect to continue to enroll subjects in Phase 2 of
DURIPANC at a steady pace.”
Read more at about DURIPANC
at ClinicalTrials.gov NCT05927142 – “Combining anti-PD-L1
immune checkpoint inhibitor durvalumab with TLR-3 agonist
rintatolimod in patients with metastatic pancreatic ductal
adenocarcinoma for therapy efficacy (DURIPANC)“
About AIM ImmunoTech Inc.
AIM ImmunoTech Inc. is an immuno-pharma company
focused on the research and development of therapeutics to treat
multiple types of cancers, immune disorders and viral diseases,
including COVID-19. The Company’s lead product is a first-in-class
investigational drug called Ampligen® (rintatolimod), a dsRNA and
highly selective TLR3 agonist immuno-modulator with broad spectrum
activity in clinical trials for globally important cancers, viral
diseases and disorders of the immune system.
For more information, please
visit aimimmuno.com and connect with the Company
on X, LinkedIn, and Facebook.
Cautionary Statement
This press release contains forward-looking
statements within the meaning of the Private Securities Litigation
Reform Act of 1995 (the “PSLRA”). Words such as “may,” “will,”
“expect,” “plan,” “anticipate,” “continue,” “believe,” “potential,”
“upcoming” and other variations thereon and similar expressions (as
well as other words or expressions referencing future events or
circumstances) are intended to identify forward-looking statements.
Many of these forward-looking statements involve a number of risks
and uncertainties. Data, pre-clinical success and clinical success
seen to date do not guarantee that Ampligen will be approved as a
therapy for pancreatic cancer. The Company urges investors to
consider specifically the various risk factors identified in its
most recent Form 10-K, and any risk factors or cautionary
statements included in any subsequent Form 10-Q or Form 8-K, filed
with the U.S. Securities and Exchange Commission. You are cautioned
not to place undue reliance on these forward-looking statements,
which speak only as of the date of this press release. Among other
things, for those statements, the Company claims the protection of
the safe harbor for forward-looking statements contained in the
PSLRA. The Company does not undertake to update any of these
forward-looking statements to reflect events or circumstances that
occur after the date hereof.
Investor Contact:
JTC Team, LLC
Jenene Thomas
908.824.0775
AIM@jtcir.com
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