RNS Number:6406K
CeNeS Pharmaceuticals PLC
01 May 2003


                              CeNeS Pharmaceutical

                             Director Shareholding


The Company was today informed by Mr A G Goodman, a director of the Company,
that the following notifiable purchase of ordinary shares took place today.

Director/Shareholder          Number of Purchase price  % interest     Number of
                        Ordinary Shares   per Ordinary   following      interest
                            Purchased      Share (p)    purchase       following
                                                                      purchase

A G Goodman                 1,500,000           2.75        7.83    13,634,404*


*4,638,176 of these ordinary shares are held by ATM Global Investments Limited,
a company controlled by A G Goodman.


In addition, A G Goodman's interest also includes a non-beneficial holding of
1,600,000 ordinary shares held by a pension fund of which A G Goodman is a
trustee.


1 May 2003






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