FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

HAMILTON EDWARD ARTHUR
2. Issuer Name and Ticker or Trading Symbol

CombiMatrix Corp [ CBMX ]
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                      __ X __ 10% Owner
_____ Officer (give title below)      _____ Other (specify below)
(Last)          (First)          (Middle)

5925 CARNEGIE BLVD., SUITE 200
3. Date of Earliest Transaction (MM/DD/YYYY)

2/25/2015
(Street)

CHARLOTTE, NC 28210
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock, $0.001 par value   2/25/2015     P    19900   A $1.97   (1) 1292857   (2) D    
Common Stock, $0.001 par value   2/26/2015     P    146000   A $2.01   (3) 1438857   (4) D    
Common Stock, $0.001 par value   2/27/2015     P    76860   A $2.04   (5) 1515717   (6) D    
Common Stock, $0.001 par value   3/2/2015     P    28200   A $2.05   (7) 1543917   (6) D    
Common Stock, $0.001 par value   3/3/2015     P    39100   A $2.01   (8) 1583017   (9) D    
Common Stock, $0.001 par value   3/4/2015     P    46260   A $2.00   (10) 1629277   (11) D    
Common Stock, $0.001 par value   3/5/2015     S    1000   D $2.04   1628277   (11) D    
Common Stock, $0.001 par value   3/6/2015     S    16700   D $2.03   (12) 1611577   (13) D    
Common Stock, $0.001 par value   3/6/2015     P    700   A $2.04   (14) 1612277   (15) D    
Common Stock, $0.001 par value   3/9/2015     P    24400   A $1.98   (16) 1636677   (17) D    
Common Stock, $0.001 par value   3/10/2015     P    17300   A $1.93   (18) 1653977   (19) D    
Common Stock, $0.001 par value   3/10/2015     S    200   D $1.93   1653777   (20) D    
Common Stock, $0.001 par value   3/11/2015     P    7500   A $1.97   (21) 1661277   (22) D    
Common Stock, $0.001 par value   3/12/2015     P    8000   A $2.01   (23) 1669277   (24) D    
Common Stock, $0.001 par value   3/12/2015     P    2900   A $2.01   (25) 2900   I   By LLC   (26)
Common Stock, $0.001 par value   3/13/2015     P    3780   A $1.98   (27) 1673057   (28) D    
Common Stock, $0.001 par value   3/16/2015     P    25600   A $1.99   (29) 1698657   (30) D    
Common Stock, $0.001 par value   3/17/2015     P    7300   A $1.98   (31) 1705957   (32) D    
Common Stock, $0.001 par value   3/18/2015     P    6900   A $1.95   (33) 1712857   (34) D    
Common Stock, $0.001 par value   3/19/2015     S    6000   D $2.19   (35) 1706857   (36) D    
Common Stock, $0.001 par value   3/19/2015     S    2900   D $2.11   (37) 0   I   By LLC   (26)
Common Stock, $0.001 par value   3/20/2015     P    2100   A $2.12   (38) 1708957   (36) D    
Common Stock, $0.001 par value   3/27/2015     P    3500   A $1.95   (39) 1712457   (40) D    
Common Stock, $0.001 par value   3/30/2015     P    1700   A $1.92   (41) 1714157   (42) D    
Common Stock, $0.001 par value   4/1/2015     P    3000   A $1.88   (43) 1717157   (42) D    
Common Stock, $0.001 par value   4/2/2015     P    1200   A $1.90   (44) 1718357   (45) D    
Common Stock, $0.001 par value   4/8/2015     P    1000   A $1.86   (46) 1719357   (47) D    
Common Stock, $0.001 par value   4/9/2015     P    9100   A $1.89   (48) 1728457   (49) D    

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Explanation of Responses:
( 1)  The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $1.89 to $2.00, inclusive. The reporting person undertakes to provide to CombiMatrix Corporation, any security holder of CombiMatrix Corporation, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in any and all footnotes to this Form 4 that report weighted average prices. Certain of the transactions reported on this statement resulted in short swing profits under Section 16(b) of the Securities Exchange Act of 1934, as amended. The reporting person has remitted $5,184.91 to the issuer, representing the profit realized in connection with the short swing transactions.
( 2)  Includes 872,508 shares over which the reporting person shares voting power and dispositive power with his spouse.
( 3)  The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $1.97 to $2.06, inclusive.
( 4)  Includes 901,408 shares over which the reporting person shares voting power and dispositive power with his spouse.
( 5)  The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.00 to $2.08, inclusive.
( 6)  Includes 957,768 shares over which the reporting person shares voting power and dispositive power with his spouse.
( 7)  The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $1.98 to $2.08, inclusive.
( 8)  The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $1.97 to $2.03, inclusive.
( 9)  Includes 996,868 shares over which the reporting person shares voting power and dispositive power with his spouse.
( 10)  The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $1.95 to $2.05, inclusive.
( 11)  Includes 1,043,128 shares over which the reporting person shares voting power and dispositive power with his spouse.
( 12)  The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $2.02 to $2.05, inclusive.
( 13)  Includes 1,611,577 shares over which the reporting person shares voting power and dispositive power with his spouse.
( 14)  The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.02 to $2.03, inclusive.
( 15)  Includes 1,032,128 shares over which the reporting person shares voting power and dispositive power with his spouse.
( 16)  The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $1.95 to $1.99, inclusive.
( 17)  Includes 1,038,128 shares over which the reporting person shares voting power and dispositive power with his spouse.
( 18)  The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $1.89 to $1.94, inclusive.
( 19)  Includes1,055,328 shares over which the reporting person shares voting power and dispositive power with his spouse.
( 20)  Includes 1,055,128 shares over which the reporting person shares voting power and dispositive power with his spouse.
( 21)  The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $1.94 to $1.99, inclusive.
( 22)  Includes 1,062,628 shares over which the reporting person shares voting power and dispositive power with his spouse.
( 23)  The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $1.99 to $2.05, inclusive.
( 24)  Includes 1,070,228 shares over which the reporting person shares voting power and dispositive power with his spouse.
( 25)  The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $1.95 to $2.05, inclusive.
( 26)  These shares are held by a limited liability company of which the reporting person is sole member and sole manager.
( 27)  The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $1.94 to $1.99, inclusive.
( 28)  Includes 1,074,008 shares over which the reporting person shares voting power and dispositive power with his spouse.
( 29)  The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $1.97 to $2.00, inclusive.
( 30)  Includes 1,099,608 shares over which the reporting person shares voting power and dispositive power with his spouse.
( 31)  The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $1.95 to $2.01, inclusive.
( 32)  Includes 1,106,908 shares over which the reporting person shares voting power and dispositive power with his spouse.
( 33)  The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $1.93 to $2.00, inclusive.
( 34)  Includes 1,113,808 shares over which the reporting person shares voting power and dispositive power with his spouse.
( 35)  The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $2.10 to $2.28, inclusive.
( 36)  Includes 1,111,808 shares over which the reporting person shares voting power and dispositive power with his spouse.
( 37)  The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $2.09 to $2.14, inclusive.
( 38)  The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.11 to $2.12, inclusive.
( 39)  The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $1.94 to $1.95, inclusive.
( 40)  Includes 1,115,308 shares over which the reporting person shares voting power and dispositive power with his spouse.
( 41)  These shares were purchased in multiple transactions at the price reported in Column 4.
( 42)  Includes 1,117,008 shares over which the reporting person shares voting power and dispositive power with his spouse.
( 43)  The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $1.86 to $1.88, inclusive.
( 44)  The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $1.86 to $1.90, inclusive.
( 45)  Includes 1,118,208 shares over which the reporting person shares voting power and dispositive power with his spouse.
( 46)  These shares were purchased in multiple transactions at the price reported in Column 4.
( 47)  Includes 1,119,208 shares over which the reporting person shares voting power and dispositive power with his spouse.
( 48)  The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $1.85 to $1.91, inclusive.
( 49)  Includes 1,128,308 shares over which the reporting person shares voting power and dispositive power with his spouse.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
HAMILTON EDWARD ARTHUR
5925 CARNEGIE BLVD.
SUITE 200
CHARLOTTE, NC 28210

X


Signatures
/s/ Edward Arthur Hamilton 4/24/2015
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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