(2) |
Based on a Schedule 13D/A filed with the SEC on January 31, 2022 by Biotechnology Value Fund, L.P., or
BVF, BVF I GP LLC, or BVF GP, Biotechnology Value Fund II, L.P., or BVF2, BVF II GP LLC, or BVF2 GP, Biotechnology Value Trading Fund OS LP, or Trading Fund OS, BVF Partners OS Ltd., or Partners OS, BVF GP Holdings LLC, or BVF GPH, BVF Partners
L.P., or Partners, BVF Inc., Mark N. Lampert and Gorjan Hrustanovic, consists of (i) 1,900,272 shares of common stock held by BVF, (ii) 1,395,925 shares of common stock held by BVF2, (iii) 208,538 shares of common stock held by Trading Fund OS and
(iv) 81,923 shares of common stock held by a certain managed account, or the Partners Managed Account. BVF GP, as the general partner of BVF, may be deemed to beneficially own the 1,900,272 shares of common stock beneficially owned by BVF. BVF2 GP,
as the general partner of BVF2, may be deemed to beneficially own the 1,395,925 shares of common stock beneficially owned by BVF2. Partners OS, as the general partner of Trading Fund OS, may be deemed to beneficially own the 208,538 shares of common
stock beneficially owned by Trading Fund OS. BVF GPH, as the sole member of each of BVF GP and BVF2 GP, may be deemed to beneficially own the 3,296,197 shares of common stock beneficially owned in the aggregate by BVF and BVF2. Partners, as the
general partner of BVF, BVF2, the investment manager of Trading Fund OS, and the sole member of Partners OS, may be deemed to beneficially own the 3,586,658 shares of common stock beneficially owned in the aggregate by BVF, BVF2, Trading Fund OS and
held in the Partners Managed Account. BVF Inc., as the general partner of Partners, may be deemed to beneficially own the 3,586,658 shares of common stock beneficially owned by Partners. Mr. Lampert, as a director and officer of BVF Inc., may
be deemed to beneficially own the 3,586,658 shares of common stock beneficially owned by BVF Inc. As of March 31, 2022, Dr. Hrustanovic beneficially owned 23,407 shares of common stock underlying certain call options which will vest within
60 days of March 31, 2022. Dr. Hrustanovic is also a member of our board of directors. Dr. Hrustanovic disclaims beneficial ownership of such shares, except to the extent of his pecuniary interest therein, if any. The business address
of BVF, BVF GP, BVF2, BVF2 GP, BVF GPH, Partners, BVF Inc., Mr. Lampert and Dr. Hrustanovic is 44 Montgomery St., 40th Floor, San Francisco, California 94104. The business address of Trading Fund OS and Partners OS is PO Box 309 Ugland
House, Grand Cayman, KY1-1104, Cayman Islands. |