Roche Holding AG (RHHBY) Monday issued a 4 billion Swiss francs ($3.4 billion) bond as part of its efforts to take over the remaining part of its U.S. unit Genetech Inc. (DNA).

The bond, which has been launched by UBS AG (UBS), has been issued at par value, or 100%, and will pay an annual coupon of 1.2%.

The bond, which is rated at Double-A-minus by Standard & Poor's, has a reopening clause, meaning that the bond's principal can be increased.

Roche has so far issued almost $40 billion in bonds for its planned takeover.

Web Sites: www.roche.com ; www.ubs.com

-By Goran Mijuk, Dow Jones Newswires, +41 43 443 80 47; goran.mijuk@dowjones.com