Canopus BioPharma Strengthens its CB1400 Platform Technology for Mucositis and Oncology Treatments Through License Agreement Wit
June 18 2008 - 7:00AM
PR Newswire (US)
LOS ANGELES, California, June 18 /PRNewswire-FirstCall/ -- Canopus
BioPharma, Inc. (OTC:CBIA), a biotechnology company developing
pharmaceutical products and assay methods for patients suffering
from infectious disease, radiation sickness, cancer and addiction,
today announced the signing of a licensing agreement with the
Wisconsin Alumni Research Foundation (WARF), an organization
serving the University of Wisconsin-Madison scientific community by
patenting the discoveries of UW-Madison researchers and licensing
these technologies to leading companies in Wisconsin, the United
States and worldwide. The agreement provides comprehensive
licensing rights and patent protection relating to Canopus' Phase
II oncology drug candidate, CB1400. "Securing the rights to the
WARF patents strengthens Canopus BioPharma's intellectual property
position for future licensing opportunities of CB1400, one of our
most exciting products," said Patrick Prendergast, Chairman and
Chief Executive Officer of Canopus BioPharma. "In the near future,
we expect to announce important results from our studies using
CB1400, which will further validate the potential significance of
our drug for oncology and related indications." Canopus BioPharma
expects to develop CB1400 as a method for preventing and reducing
mucositis (lesions in the gastrointestinal and oral mucosa caused
by chemo- and/or radiotherapy). The domestic market alone for a
preventative anti-mucositis agent is estimated to be over $1
billion per annum. The compound underlying CB1400 had been
previously developed and patented by a major pharmaceutical company
as an anti-parasitic agent. Canopus discovered that this approved
drug was highly effective for an alternative indication,
specifically for use in preventing mucositis. Canopus BioPharma's
market opportunity with CB1400 includes various applications
associated with cancer therapy and cancer treatment side effects.
CB1400, a former anti-schistosomal drug, is currently in phase II
clinical development by Canopus as an anti-mucositis preventative
agent in patients receiving radio- and/or chemotherapy treatment.
CB1400 alone and in combination with both cisplatin and cetuximab
(Erbitux), has also been shown to inhibit tumor growth in two mice
models of lung cancer, thus demonstrating the broad capabilities of
this compound in the treatment of cancer. About the Wisconsin
Alumni Research Foundation: The Wisconsin Alumni Research
Foundation (WARF) supports research at the University of
Wisconsin-Madison by protecting the intellectual property of
University faculty, staff and students, and licensing inventions
resulting from their work. Through these efforts, university ideas
benefit the public by bringing resources back to the university to
continue the cycle of investment, research and invention. WARF
(http://www.warf.org/) was established in 1925 as the first
university-based technology transfer office in the world. About
Canopus BioPharma, Inc.: Canopus BioPharma, Inc. (OTC:CBIA) is
dedicated to providing the safest, most cost effective and
efficacious pharmaceutical products and assay methods in the areas
of infectious disease, radiation protection, cancer, and addiction.
With innovative science, proven research and development
leadership, and superior products and compounds, Canopus BioPharma
has, since 2001, been committed to becoming a market trend setter
in a new era of healthcare. In addition, the Company is a world
leader in the development of novel camelid antibody products to
provide unique avenues of progress and improvement in assay methods
and monitoring capabilities for physicians, patients and
researchers, initially for food chain protection applications.
Canopus maintains staff in Australia, South Africa, Ireland, Panama
and the USA. Additional information on the Company is available at
http://www.canopusbiopharma.com/. DATASOURCE: Canopus BioPharma,
Inc. CONTACT: Canopus BioPharma Contact: Len Rothstein, President,
Tel: +1-818-980-5008, Fax: +1-818-980-5088,
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