Canopus BioPharma Announces Positive Results in Human Study of Novel Peptide Cancer Vaccine
November 03 2008 - 7:01AM
Business Wire
Canopus BioPharma, Inc. (OTC:CBIA); (www.canopusbiopharma.com)
today announced that it has successfully completed the second phase
of its cancer vaccine development. The specialized laboratory study
was analyzed at the Southern Research Institute in Birmingham,
Alabama. The study used the blood of healthy human volunteers,
vaccinated with Canopus Biopharma�s cancer vaccine peptides, which
then demonstrated anti-cancer properties against�a panel of 12
human cancer cell lines in tissue culture. For the first time,
successful human testing confirms that Canopus BioPharma�s
proprietary, patented�use of these cancer-targeted peptide antigens
is effective as a vaccine against human cancer cells. When used as
a vaccine in healthy volunteers, the peptide antigens generate
antibodies that are non-toxic to normal cells, but significantly
effective in destroying human cancer cells in-vitro. In effect, the
peptide antigens work by stimulating a person�s own immune system,
to protect the individual from developing certain forms of cancer.
�Successful results from this series of laboratory tests, using
vaccinated,�healthy volunteers, confirms proof of principle in
humans,� said Elizabeth Shanahan-Prendergast, President of Oncology
at Canopus BioPharma. �In the laboratory, the vaccinated human
blood demonstrated that it can significantly inhibit the growth of
a broad range of human cancer cells -- including�colorectal,
prostate, small-cell lung, pancreatic, ovarian and breast -- when
compared to a control sample of non-vaccinated human blood.�
�Southern Research Institute is a recognized leader in scientific
research, serving clients throughout the biotechnology industry,
including the National Institutes of Health and the U.S.
Environmental Protection Agency,� said Patrick T. Prendergast,
Chairman and CEO, Canopus BioPharma. �According to Kalorama
Information�s 2007 report, the cancer vaccine market will generate
up to $700 million in potential new revenue this year and $8.4
billion by 2012. Now that we have proof of principle, in a human
in-vivo study, we will be actively looking for a co-development
partner to bring this novel vaccine to market as soon as possible.�
About Canopus BioPharma, Inc. Canopus BioPharma, Inc. (OTC:CBIA) is
dedicated to providing the safest, most cost effective and
efficacious pharmaceutical products and assay methods in the areas
of infectious disease, radiation protection, cancer, and addiction.
With innovative science, proven research and development
leadership, and superior products and compounds, Canopus BioPharma
has, since 2001, been committed to becoming a market trend setter
in a new era of healthcare. In addition, the Company is a world
leader in the development of novel camelid antibody products to
provide unique avenues of progress and improvement in assay methods
and monitoring capabilities for physicians, patients and
researchers, initially for food chain protection applications.
Canopus maintains staff in Australia, South Africa, Ireland, and
the USA. Additional information on the company is available at
www.canopusbiopharma.com.
Canopus Biopharma (PK) (USOTC:CBIA)
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